AR090318A1 - Lotes de adenovirus recombinantes con extremos terminales alterados - Google Patents
Lotes de adenovirus recombinantes con extremos terminales alteradosInfo
- Publication number
- AR090318A1 AR090318A1 ARP130100798A ARP130100798A AR090318A1 AR 090318 A1 AR090318 A1 AR 090318A1 AR P130100798 A ARP130100798 A AR P130100798A AR P130100798 A ARP130100798 A AR P130100798A AR 090318 A1 AR090318 A1 AR 090318A1
- Authority
- AR
- Argentina
- Prior art keywords
- batches
- altered
- adenovirus
- extreme terminals
- adenovirus recombinants
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
- C12N7/02—Recovery or purification
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/10011—Adenoviridae
- C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
- C12N2710/10322—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/10011—Adenoviridae
- C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
- C12N2710/10341—Use of virus, viral particle or viral elements as a vector
- C12N2710/10343—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/10011—Adenoviridae
- C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
- C12N2710/10351—Methods of production or purification of viral material
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Virology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Plant Pathology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Una composición que comprende una pluralidad de partículas de adenovirus recombinantes, que pueden ser adenovirus humanos recombinantes de los serotipos 5, 26, 34, 35, 48, 49 ó 50 o un adenovirus simio recombinante, donde los genomas de esencialmente todas las partículas de adenovirus en dicha composición comprende la secuencia de nucleótidos CTATCTAT como nucleótidos 5 terminales, y métodos para producir dichas composiciones.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP12159009 | 2012-03-12 |
Publications (1)
Publication Number | Publication Date |
---|---|
AR090318A1 true AR090318A1 (es) | 2014-11-05 |
Family
ID=49160272
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP130100798A AR090318A1 (es) | 2012-03-12 | 2013-03-12 | Lotes de adenovirus recombinantes con extremos terminales alterados |
Country Status (17)
Country | Link |
---|---|
EP (1) | EP2825640B1 (es) |
JP (1) | JP5770952B2 (es) |
KR (1) | KR102044051B1 (es) |
CN (1) | CN104379733B (es) |
AR (1) | AR090318A1 (es) |
AU (1) | AU2013231423B2 (es) |
CA (1) | CA2864956C (es) |
DK (1) | DK2825640T3 (es) |
EA (1) | EA034284B1 (es) |
ES (1) | ES2582504T3 (es) |
HU (1) | HUE027839T2 (es) |
NZ (1) | NZ628385A (es) |
PL (1) | PL2825640T3 (es) |
SG (1) | SG11201405228VA (es) |
SI (1) | SI2825640T1 (es) |
TW (1) | TWI633188B (es) |
WO (1) | WO2013135615A1 (es) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2971008B1 (en) | 2013-03-14 | 2018-07-25 | Salk Institute for Biological Studies | Oncolytic adenovirus compositions |
KR102236497B1 (ko) | 2013-04-25 | 2021-04-06 | 얀센 백신스 앤드 프리벤션 비.브이. | 안정화된 가용성 예비융합 rsv f 폴리펩타이드 |
AP2015008893A0 (en) | 2013-06-17 | 2015-12-31 | Crucell Holland Bv | Stabilized soluble pre-fusion rsv f polypeptides |
CN107847581B (zh) | 2015-07-07 | 2022-03-22 | 扬森疫苗与预防公司 | 稳定化的可溶性融合前rsv f多肽 |
US10456462B2 (en) | 2015-07-07 | 2019-10-29 | Janssen Vaccines & Preventions B.V. | Vaccine against RSV |
GB201513010D0 (en) * | 2015-07-23 | 2015-09-09 | Glaxosmithkline Biolog Sa | Novel formulation |
JP7054527B2 (ja) * | 2016-02-23 | 2022-04-14 | ソーク インスティテュート フォー バイオロジカル スタディーズ | アデノウイルスの複製動態を測定するための高スループットアッセイ |
JP7015551B2 (ja) | 2016-02-23 | 2022-02-15 | ソーク インスティテュート フォー バイオロジカル スタディーズ | ウイルス動態への影響を最小限にするための治療用アデノウイルスにおける外因性遺伝子発現 |
PT3439672T (pt) | 2016-04-05 | 2021-02-24 | Janssen Vaccines & Prevention Bv | Proteína f do rsv pré-fusão solúvel e estabilizada para uso na profilaxia de infeção por rsv |
WO2017174564A1 (en) | 2016-04-05 | 2017-10-12 | Janssen Vaccines & Prevention B.V. | Vaccine against rsv |
BR112018072865A2 (pt) * | 2016-05-12 | 2019-04-30 | Janssen Vaccines & Prevention B.V. | promotor bidirecional potente e equilibrado |
PL3464331T3 (pl) | 2016-05-30 | 2021-04-19 | Janssen Vaccines & Prevention B.V. | Stabilizowane przedfuzyjne białka F RSV |
WO2018011196A1 (en) | 2016-07-14 | 2018-01-18 | Janssen Vaccines & Prevention B.V. | Hpv vaccines |
CA3045892A1 (en) | 2016-12-12 | 2018-06-21 | Salk Institute For Biological Studies | Tumor-targeting synthetic adenoviruses and uses thereof |
CA3061278A1 (en) | 2017-05-17 | 2018-11-22 | Janssen Vaccines & Prevention B.V. | Methods and compositions for inducing protective immunity against rsv infection |
BR112020004143A2 (pt) | 2017-09-15 | 2020-09-01 | Janssen Vaccines & Prevention B.V. | método para a indução segura de imunidade contra vírus sincicial respiratório (rsv) |
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US5057540A (en) | 1987-05-29 | 1991-10-15 | Cambridge Biotech Corporation | Saponin adjuvant |
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US20030180936A1 (en) | 2002-03-15 | 2003-09-25 | Memarzadeh Bahram Eric | Method for the purification, production and formulation of oncolytic adenoviruses |
US7285265B2 (en) | 2002-04-25 | 2007-10-23 | Crucell Holland B.V. | Stable adenoviral vectors and methods for propagation thereof |
PL215165B1 (pl) | 2002-04-25 | 2013-10-31 | Crucell Holland Bv | Rekombinowany wektor adenowirusowy oraz sposób wytwarzania rekombinowanego wektora adenowirusowego |
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CA2742474C (en) | 2008-11-03 | 2016-05-31 | Crucell Holland B.V. | Method for the production of adenoviral vectors |
WO2010085984A1 (en) | 2009-02-02 | 2010-08-05 | Okairos Ag | Simian adenovirus nucleic acid- and amino acid-sequences, vectors containing same, and uses thereof |
AU2010209938A1 (en) | 2009-02-02 | 2011-08-25 | Glaxosmithkline Biologicals Sa | Simian adenovirus nucleic acid- and amino acid-sequences, vectors containing same, and uses thereof |
WO2010096561A1 (en) | 2009-02-18 | 2010-08-26 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Synthetic hiv/siv gag proteins and uses thereof |
CA2776461C (en) | 2009-10-15 | 2020-08-25 | Crucell Holland B.V. | Method for the purification of adenovirus particles. |
JP5465331B2 (ja) | 2009-10-15 | 2014-04-09 | クルセル ホランド ベー ヴェー | 高細胞密度の培養物からのアデノウイルスの精製方法 |
DK2536829T3 (en) | 2010-02-15 | 2016-07-04 | Crucell Holland Bv | A process for the production of Ad26-adenovirus vectors |
-
2013
- 2013-03-11 SI SI201330239A patent/SI2825640T1/sl unknown
- 2013-03-11 JP JP2014561393A patent/JP5770952B2/ja active Active
- 2013-03-11 HU HUE13708445A patent/HUE027839T2/en unknown
- 2013-03-11 EP EP13708445.5A patent/EP2825640B1/en active Active
- 2013-03-11 AU AU2013231423A patent/AU2013231423B2/en active Active
- 2013-03-11 ES ES13708445.5T patent/ES2582504T3/es active Active
- 2013-03-11 PL PL13708445.5T patent/PL2825640T3/pl unknown
- 2013-03-11 EA EA201491676A patent/EA034284B1/ru not_active IP Right Cessation
- 2013-03-11 WO PCT/EP2013/054846 patent/WO2013135615A1/en active Application Filing
- 2013-03-11 KR KR1020147026543A patent/KR102044051B1/ko active IP Right Grant
- 2013-03-11 DK DK13708445.5T patent/DK2825640T3/en active
- 2013-03-11 CA CA2864956A patent/CA2864956C/en active Active
- 2013-03-11 CN CN201380013551.5A patent/CN104379733B/zh active Active
- 2013-03-11 NZ NZ628385A patent/NZ628385A/en unknown
- 2013-03-11 SG SG11201405228VA patent/SG11201405228VA/en unknown
- 2013-03-12 TW TW102108773A patent/TWI633188B/zh not_active IP Right Cessation
- 2013-03-12 AR ARP130100798A patent/AR090318A1/es active IP Right Grant
Also Published As
Publication number | Publication date |
---|---|
CA2864956C (en) | 2021-11-09 |
WO2013135615A1 (en) | 2013-09-19 |
AU2013231423A1 (en) | 2014-08-28 |
SI2825640T1 (sl) | 2016-08-31 |
TWI633188B (zh) | 2018-08-21 |
TW201336993A (zh) | 2013-09-16 |
EA034284B1 (ru) | 2020-01-24 |
CN104379733B (zh) | 2016-01-20 |
PL2825640T3 (pl) | 2016-10-31 |
EP2825640A1 (en) | 2015-01-21 |
NZ628385A (en) | 2016-09-30 |
CA2864956A1 (en) | 2013-09-19 |
ES2582504T3 (es) | 2016-09-13 |
KR20140139509A (ko) | 2014-12-05 |
SG11201405228VA (en) | 2014-11-27 |
JP5770952B2 (ja) | 2015-08-26 |
EP2825640B1 (en) | 2016-04-27 |
KR102044051B1 (ko) | 2019-11-12 |
CN104379733A (zh) | 2015-02-25 |
HUE027839T2 (en) | 2016-11-28 |
EA201491676A1 (ru) | 2014-12-30 |
AU2013231423B2 (en) | 2018-10-04 |
JP2015511597A (ja) | 2015-04-20 |
DK2825640T3 (en) | 2016-08-01 |
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