AR084169A1 - COMBINATION THAT INCLUDES A FAMILY DERIVATIVE OF COMBRETASTATINAS AND CETUXIMAB - Google Patents

COMBINATION THAT INCLUDES A FAMILY DERIVATIVE OF COMBRETASTATINAS AND CETUXIMAB

Info

Publication number
AR084169A1
AR084169A1 ARP110104553A ARP110104553A AR084169A1 AR 084169 A1 AR084169 A1 AR 084169A1 AR P110104553 A ARP110104553 A AR P110104553A AR P110104553 A ARP110104553 A AR P110104553A AR 084169 A1 AR084169 A1 AR 084169A1
Authority
AR
Argentina
Prior art keywords
cetuximab
combination
combretastatinas
family derivative
family
Prior art date
Application number
ARP110104553A
Other languages
Spanish (es)
Inventor
Chantal Carrez
Brigitte Demers
Yvette Ruffin
Patricia Vrignaud
Original Assignee
Sanofi Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Sa filed Critical Sanofi Sa
Publication of AR084169A1 publication Critical patent/AR084169A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2863—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators

Abstract

Combinación farmacéutica que comprende un derivado de la familia de las combretastatinas, tal como la ombrabulina, que puede estar en forma de base o en forma de una sal farmacéuticamente aceptable, y cetuximab.Reivindicación 2: Combinación según la reivindicación 1 en la que el derivado de la familia de las combretastatinas es AVE8062 de fórmula (1), que puede estar en forma de base o en forma de sal farmacéuticamente aceptable.Pharmaceutical combination comprising a derivative of the family of combretastatins, such as ombrabulin, which may be in the form of a base or in the form of a pharmaceutically acceptable salt, and cetuximab. Claim 2: Combination according to claim 1 wherein the derivative of the family of combretastatins is AVE8062 of formula (1), which may be in the form of a base or in the form of a pharmaceutically acceptable salt.

ARP110104553A 2010-12-09 2011-12-06 COMBINATION THAT INCLUDES A FAMILY DERIVATIVE OF COMBRETASTATINAS AND CETUXIMAB AR084169A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR1060293A FR2968557A1 (en) 2010-12-09 2010-12-09 ANTITUMOR COMBINATION COMPRISING A DRIFT OF THE COMBRETASTATIN FAMILY AND THE CETUXIMAB

Publications (1)

Publication Number Publication Date
AR084169A1 true AR084169A1 (en) 2013-04-24

Family

ID=43837735

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP110104553A AR084169A1 (en) 2010-12-09 2011-12-06 COMBINATION THAT INCLUDES A FAMILY DERIVATIVE OF COMBRETASTATINAS AND CETUXIMAB

Country Status (5)

Country Link
AR (1) AR084169A1 (en)
FR (1) FR2968557A1 (en)
TW (1) TW201306833A (en)
UY (1) UY33789A (en)
WO (1) WO2012076688A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2016503399A (en) * 2012-10-25 2016-02-04 ノバルティス アーゲー combination
US20170128592A1 (en) * 2015-10-01 2017-05-11 Indian Institute Of Technology, Bombay Targeted polymeric nano-complexes as drug delivery system
CN112225673B (en) * 2020-11-13 2022-08-02 义乌市华耀医药科技有限公司 Amino combretastatin derivative and application thereof

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4996237A (en) 1987-01-06 1991-02-26 Arizona Board Of Regents Combretastatin A-4
TW325458B (en) 1993-09-08 1998-01-21 Ajinomoto Kk Stilbene derivatives and pharmaceutical compositions comprising the same for anti-cancer
US5731353A (en) 1993-09-08 1998-03-24 Ajinomoto Co., Inc. Stilbene derivatives and pharmaceutical compositions containing them
TW334418B (en) 1995-03-07 1998-06-21 Ajinomoto Kk Stilbene derivatives and pharmaceutical compositions
EP1068870B1 (en) 1998-04-03 2006-06-07 Ajinomoto Co., Inc. Antitumor agents
US20020183266A1 (en) 2001-03-15 2002-12-05 Aventis Pharma, S.A. Combination comprising combretastatin and anticancer agents
DK1407784T3 (en) 2001-06-25 2011-02-28 Ajinomoto Kk Antitumor agents
FR2838437B1 (en) 2002-04-11 2004-06-04 Aventis Pharma Sa PROCESSES FOR THE PREPARATION OF COMBRETASTATINS
GB0410817D0 (en) * 2004-05-14 2004-06-16 Angiogene Pharm Ltd Vascular damaging therapy
FR2895258B1 (en) 2005-12-22 2008-03-21 Aventis Pharma Sa COMBINATION COMPRISING COMBRETASTATIN AND ANTICANCER AGENTS
CA2708149A1 (en) * 2007-12-13 2009-06-18 Novartis Ag Combinations of therapeutic agents for treating cancer
WO2009103076A1 (en) * 2008-02-15 2009-08-20 Oxigene, Inc. Methods and compositions for enhancing the efficacy of rtk inhibitors
FR2945210B1 (en) * 2009-05-07 2011-07-01 Sanofi Aventis ANTITUMOR COMBINATION COMPRISING AVE8062 AND SORAFENIB

Also Published As

Publication number Publication date
FR2968557A1 (en) 2012-06-15
TW201306833A (en) 2013-02-16
WO2012076688A1 (en) 2012-06-14
UY33789A (en) 2012-07-31

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Legal Events

Date Code Title Description
FA Abandonment or withdrawal