AR079032A1 - PREPARATION OF A FACTOR CONCENTRATE H - Google Patents
PREPARATION OF A FACTOR CONCENTRATE HInfo
- Publication number
- AR079032A1 AR079032A1 ARP100104215A AR079032A1 AR 079032 A1 AR079032 A1 AR 079032A1 AR P100104215 A ARP100104215 A AR P100104215A AR 079032 A1 AR079032 A1 AR 079032A1
- Authority
- AR
- Argentina
- Prior art keywords
- factor
- concentration
- preparation
- salts
- obtaining
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/472—Complement proteins, e.g. anaphylatoxin, C3a, C5a
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Toxicology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
Abstract
Procedimiento de obtencion de una composicion líquida inyectable del factor H, que comprende (a) la obtencion de una composicion solida obtenida por liofilizacion de un volumen V de una formulacion líquida que comprende el factor H de concentracion C1, arginina o una de sus sales, de concentracion C2, citrato de sodio, de concentracion C3, luego (b) la adicion de un volumen V/n de agua, con n>1, por lo cual se obtiene una composicion líquida inyectable que contiene el factor H en una concentracion C=Clxn. Reivindicacion 2: Procedimiento de acuerdo con la reivindicacion 1, en el que n es igual a 2. Reivindicacion 3: Procedimiento de acuerdo con la reivindicacion 1 o 2, en el que el factor H proviene de plasma humano. Reivindicacion 8: Procedimiento de acuerdo con una de las reivindicaciones 1 a 7, en el que la formulacion líquida del factor H antes de la liofilizacion comprende arginina, con preferencia, en forma de su clorhidrato, citrato de sodio, con preferencia, en forma dihidratada, isoleucina, glicina y lisina o una de sus sales.Method of obtaining an injectable liquid composition of factor H, comprising (a) obtaining a solid composition obtained by lyophilization of a volume V of a liquid formulation comprising the concentration factor H C1, arginine or one of its salts, of concentration C2, sodium citrate, of concentration C3, then (b) the addition of a volume V / n of water, with n> 1, whereby an injectable liquid composition containing factor H in a concentration C is obtained = Clxn. Claim 2: Procedure according to claim 1, wherein n is equal to 2. Claim 3: Procedure according to claim 1 or 2, wherein factor H comes from human plasma. Claim 8: Method according to one of claims 1 to 7, wherein the liquid formulation of factor H before lyophilization comprises arginine, preferably, in the form of its hydrochloride, sodium citrate, preferably, in dihydrate form , isoleucine, glycine and lysine or one of its salts.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0958046A FR2952539B1 (en) | 2009-11-16 | 2009-11-16 | PREPARATION OF H-FACTOR CONCENTRATE |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR079032A1 true AR079032A1 (en) | 2011-12-21 |
Family
ID=42483955
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP100104215 AR079032A1 (en) | 2009-11-16 | 2010-11-15 | PREPARATION OF A FACTOR CONCENTRATE H |
Country Status (3)
| Country | Link |
|---|---|
| AR (1) | AR079032A1 (en) |
| FR (1) | FR2952539B1 (en) |
| WO (1) | WO2011058284A1 (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5711369B2 (en) | 2011-06-24 | 2015-04-30 | 旭化成メディカル株式会社 | Method for producing protein preparation |
| FR2983212A1 (en) | 2011-11-28 | 2013-05-31 | Lfb Biotechnologies | ANTI-FH APTAMERS, PROCESS FOR OBTAINING THEM AND USES THEREOF |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0742235B2 (en) * | 1985-11-08 | 1995-05-10 | 三共株式会社 | Prophylactic / therapeutic agent for autoimmune diseases |
| NZ595305A (en) * | 2005-02-14 | 2013-06-28 | Univ Iowa Res Found | Methods and reagents for treatment and diagnosis of age-related macular degeneration |
| EP1928483B1 (en) | 2005-09-19 | 2016-12-28 | CSL Behring GmbH | Factor h for the treatment of tubulointerstitial fibrosis and progressive renal failure |
| FR2894145B1 (en) | 2005-12-07 | 2008-10-17 | Lab Francais Du Fractionnement | USE OF FACTOR H OF THE COMPLEMENT AS A MEDICINAL PRODUCT |
| ES2595059T3 (en) * | 2007-03-20 | 2016-12-27 | Csl Behring Gmbh | Methods for the industrial scale production of therapeutic preparations of complement factor H from human plasma |
-
2009
- 2009-11-16 FR FR0958046A patent/FR2952539B1/en not_active Expired - Fee Related
-
2010
- 2010-11-15 WO PCT/FR2010/052424 patent/WO2011058284A1/en active Application Filing
- 2010-11-15 AR ARP100104215 patent/AR079032A1/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2011058284A1 (en) | 2011-05-19 |
| FR2952539A1 (en) | 2011-05-20 |
| FR2952539B1 (en) | 2012-01-13 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FB | Suspension of granting procedure |