AR070731A1 - Composicion farmaceutica para farmacos poco solubles - Google Patents
Composicion farmaceutica para farmacos poco solublesInfo
- Publication number
- AR070731A1 AR070731A1 ARP090100726A ARP090100726A AR070731A1 AR 070731 A1 AR070731 A1 AR 070731A1 AR P090100726 A ARP090100726 A AR P090100726A AR P090100726 A ARP090100726 A AR P090100726A AR 070731 A1 AR070731 A1 AR 070731A1
- Authority
- AR
- Argentina
- Prior art keywords
- dosage form
- solid dosage
- active pharmaceutical
- pharmaceutical ingredient
- solid
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Neurology (AREA)
- Epidemiology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Hospice & Palliative Care (AREA)
- Rheumatology (AREA)
- Psychology (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Otolaryngology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Reivindicacion 1: Una forma de dosificacion solida, para la liberacion de un ingrediente farmacéutico activo poco soluble (IFA), comprendiendo la forma de dosificacion solida una dispersion solida, caracterizada porque la dispersion solida comprende un ingrediente farmacéutico activo perteneciente a la Clase II de BCS, un vehículo amorfo y un surfactante, en la que la cantidad de surfactante es de 0,5 a 30% del peso total de la dispersion solida, y en la que al menos el 30% del ingrediente farmacéutico activo está en una forma amorfa. Reivindicacion 2: Una forma de dosificacion solida de acuerdo con la reivindicacion 1, caracterizado porque la forma de dosificacion es para la liberacion rápida del IFA. Reivindicacion 5: Una forma de dosificacion solida de acuerdo con la reivindicacion 1, caracterizado porque la forma de dosificacion es para la liberacion sostenida del IFA. Reivindicacion 7: Una forma de dosificacion solida de acuerdo con cualquiera de las reivindicaciones anteriores, caracterizado porque la forma de dosificacion es una formulacion de cápsula, estando contenida la dispersion solida en una envoltura externa de un material farmacéuticamente aceptable. Reivindicacion 9: Una forma de dosificacion solida de acuerdo con la reivindicacion 8, caracterizado porque la forma de dosificacion es un comprimido. Reivindicacion 25: Una forma de dosificacion solida de acuerdo con la reivindicacion 24, caracterizado porque el ingrediente farmacéutico activo se selecciona de fármacos analgésicos, antipiréticos, antimigranosos, antidepresivos, relajantes musculares, antiepilépticos, anticonvulsivos, antiparkinsonianos, antieméticos, ansiolíticos, fármacos usados en el tratamiento de trastornos afectivos como trastorno bipolar, antipsicoticos y fármacos contra el Alzheimer. Reivindicacion 26: Una forma de dosificacion solida de acuerdo con cualquiera de las reivindicaciones 1 a 23, caracterizado porque el ingrediente farmacéutico activo es un inhibidor de COMT, un inhibidor de FAAH, un inhibidor de dopamina beta-hidroxilasa o un antagonista del canal del sodio. Reivindicacion 45: Una forma de dosificacion solida de acuerdo con cualquiera de las reivindicaciones anteriores, caracterizado porque el ingrediente farmacéutico activo no se disuelve en 250 ml de tampones acuosos con un pH entre 1-7,5.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US3219008P | 2008-02-28 | 2008-02-28 |
Publications (1)
Publication Number | Publication Date |
---|---|
AR070731A1 true AR070731A1 (es) | 2010-04-28 |
Family
ID=40577908
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP090100726A AR070731A1 (es) | 2008-02-28 | 2009-03-02 | Composicion farmaceutica para farmacos poco solubles |
Country Status (12)
Country | Link |
---|---|
US (1) | US20110014282A1 (es) |
EP (1) | EP2259777A2 (es) |
JP (1) | JP2011513301A (es) |
KR (1) | KR20100126452A (es) |
CN (1) | CN101959504A (es) |
AR (1) | AR070731A1 (es) |
AU (1) | AU2009217865A1 (es) |
BR (1) | BRPI0908340A2 (es) |
CA (1) | CA2715802A1 (es) |
IL (1) | IL207512A0 (es) |
MX (1) | MX2010009043A (es) |
WO (1) | WO2009108077A2 (es) |
Families Citing this family (42)
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IL169855A (en) * | 2005-07-25 | 2014-05-28 | Elta Systems Ltd | A system and method for locating a receiver location |
EP1907382B1 (en) | 2005-07-26 | 2015-05-27 | Bial-Portela & CA, S.A. | Nitrocatechol derivatives as comt inhibitors |
EP1845097A1 (en) * | 2006-04-10 | 2007-10-17 | Portela & Ca., S.A. | Oxadiazole derivatives as COMT inhibitors |
DK2481410T3 (en) | 2007-01-31 | 2016-10-24 | Bial - Portela & Ca S A | Nitrocatecholderivater as COMT inhibitors administered in a specific dosage regimen |
CA2718772C (en) * | 2008-03-17 | 2017-05-02 | David Alexander Learmonth | Crystal forms of 5-[3-(2,5-dichloro-4,6-dimethyl-1-oxy-pyridine-3-yl)[1,2,4]oxadiazol-5-yl]-3-nit robenzene-1,2-diol |
PL2413912T3 (pl) | 2009-04-01 | 2019-09-30 | Bial-Portela & Ca, S.A. | Preparaty farmaceutyczne zawierające pochodne nitrokatecholu oraz metody ich wytwarzania |
JP5499703B2 (ja) * | 2009-12-28 | 2014-05-21 | ライオン株式会社 | イブプロフェン含有製剤 |
WO2011107653A2 (en) | 2010-03-04 | 2011-09-09 | Orion Corporation | Method for treating parkinson's disease |
US9044394B2 (en) * | 2010-10-18 | 2015-06-02 | PruGen IP Holdings, Inc. | Bioavailability enhancement delivery composition |
US20140045900A1 (en) | 2011-02-11 | 2014-02-13 | Bial-Portela & Ca, S.A. | Administration regime for nitrocatechols |
CN102716493B (zh) * | 2011-03-31 | 2014-05-28 | 天津药物研究院 | 含无定型态阿戈美拉汀的共聚物、其制备方法、其药物组合物及用途 |
KR20130106456A (ko) * | 2011-04-29 | 2013-09-30 | 한국유나이티드제약 주식회사 | 약물 방출제어용 조성물 |
CN102178642A (zh) * | 2011-04-29 | 2011-09-14 | 苏州大学 | 一种替米沙坦固体分散体及其制备方法 |
US20150011525A1 (en) | 2011-09-13 | 2015-01-08 | Isp Investments Inc. | Solid dispersion of poorly soluble compounds comprising crospovidone and at least one water-soluble polymer |
KR101332223B1 (ko) * | 2011-09-19 | 2013-11-25 | 충남대학교산학협력단 | 프란루카스트 나노 고체 분산체의 제조방법 및 이로써 제조된 나노 고체 분산체 |
EP2589376B1 (en) * | 2011-11-01 | 2016-09-21 | Inopharm Limited | Oral disintegrating composition of anti-histamine agents |
CN102641245B (zh) * | 2011-11-02 | 2014-02-26 | 中国科学院过程工程研究所 | 一种装载难溶性药物的壳聚糖-壳聚糖衍生物纳米球、制备方法及其作为口服制剂的应用 |
EP3604299B1 (en) | 2011-12-13 | 2023-07-26 | Bial-Portela & CA, S.A. | Chemical compound useful as intermediate for preparing a catechol-0-methyl transferase inhibitor |
US20130172375A1 (en) | 2011-12-13 | 2013-07-04 | Hoffmann-La Roche Inc. | Pharmaceutical composition |
WO2013117963A1 (en) * | 2012-02-09 | 2013-08-15 | Piramal Enterprises Limited | Stable oral tablet dosage form of an antidiabetic compound |
AR090245A1 (es) * | 2012-03-06 | 2014-10-29 | Otsuka Pharma Co Ltd | Preparacion solida oral de liberacion sostenida, metodo de preparacion |
IN2012DE00674A (es) * | 2012-03-07 | 2015-08-21 | Nat Inst Of Pharmaceutical Education And Res Niper | |
KR101280005B1 (ko) * | 2012-03-16 | 2013-07-05 | 유우영 | 무수무복계물질 |
CN102988297A (zh) * | 2012-12-21 | 2013-03-27 | 无锡泓兴生物医药科技有限公司 | 罗氟司特固体分散体及含有其的药物组合物 |
CA2899032A1 (en) | 2013-02-01 | 2014-08-07 | Glialogix, Inc. | Compositions and methods for the treatment of neurodegenerative and other diseases |
CN103360357B (zh) * | 2013-08-07 | 2015-07-22 | 中国药科大学 | 辛伐他丁格列齐特共无定型物 |
RU2017120184A (ru) | 2014-11-28 | 2018-12-28 | БИАЛ - ПОРТЕЛА ЭНД Ка, С.А. | Лекарства для замедления течения болезни паркинсона |
US10596118B2 (en) | 2015-03-10 | 2020-03-24 | Shionogi, Inc. | Solid dispersions |
KR20170039347A (ko) | 2015-10-01 | 2017-04-11 | 삼진제약주식회사 | 레바미피드를 함유하는 신규한 점안 조성물 및 이의 제조방법 |
CN109069460A (zh) * | 2016-05-09 | 2018-12-21 | 分散技术有限责任公司 | 改进的药物制剂 |
CN105853383B (zh) * | 2016-05-23 | 2019-04-30 | 苏州中化药品工业有限公司 | 一种治疗糖尿病性神经病变的药物组合物及其制备方法 |
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CN106727388A (zh) * | 2017-03-27 | 2017-05-31 | 华益药业科技(安徽)有限公司 | 乙酰唑胺片及其制备方法 |
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WO2021202928A1 (en) * | 2020-04-01 | 2021-10-07 | Board Of Regents, The University Of Texas System | Pharmaceutical compositions of niclosamide |
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KR102378590B1 (ko) * | 2020-09-28 | 2022-03-24 | (주)위바이오트리 | 난용성 약물을 포함하는 금속 (수)산화물 복합체, 이의 제조 방법 및 이를 포함하는 약학적 조성물 |
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WO2005006945A2 (en) * | 2003-07-03 | 2005-01-27 | The Salk Institute For Biological Studies | Methods for treating neural disorders and compounds useful therefor |
KR20050031847A (ko) * | 2003-09-30 | 2005-04-06 | 삼성전자주식회사 | 복수의 재생경로를 가지는 동영상 데이터에 대한 텍스트기반의 자막 정보가 기록된 저장 매체, 재생 장치 및 그재생 방법 |
GB0325956D0 (en) * | 2003-11-06 | 2003-12-10 | Addex Pharmaceuticals Sa | Novel compounds |
WO2005105780A2 (en) * | 2004-04-28 | 2005-11-10 | Vertex Pharmaceuticals Incorporated | Compositions useful as inhibitors of rock and other protein kinases |
WO2007001451A2 (en) * | 2004-11-09 | 2007-01-04 | Board Of Regents, The University Of Texas System | Stabilized hme composition with small drug particles |
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KR100678824B1 (ko) * | 2005-02-04 | 2007-02-05 | 한미약품 주식회사 | 용해성이 증가된 무정형 타크로리무스 고체분산체 및 이를포함하는 약제학적 조성물 |
CA2606087A1 (en) * | 2005-04-26 | 2006-11-02 | Neurosearch A/S | Novel oxadiazole derivatives and their medical use |
GB0510139D0 (en) * | 2005-05-18 | 2005-06-22 | Addex Pharmaceuticals Sa | Novel compounds B1 |
CA2610655A1 (en) * | 2005-06-03 | 2006-12-14 | Abbott Laboratories | Cyclobutyl amine derivatives |
FR2889525A1 (fr) * | 2005-08-04 | 2007-02-09 | Palumed Sa | Nouveaux derives de polyquinoleines et leur utilisation therapeutique. |
US20070048384A1 (en) * | 2005-08-26 | 2007-03-01 | Joerg Rosenberg | Pharmaceutical compositions |
US20090111778A1 (en) * | 2005-11-18 | 2009-04-30 | Richard Apodaca | 2-Keto-Oxazoles as Modulators of Fatty Acid Amide Hydrolase |
EP1956013B1 (en) * | 2005-11-30 | 2016-04-13 | Fujifilm RI Pharma Co., Ltd. | Diagnostic and remedy for disease caused by amyloid aggregation and/or deposition |
EP1845097A1 (en) * | 2006-04-10 | 2007-10-17 | Portela & Ca., S.A. | Oxadiazole derivatives as COMT inhibitors |
KR20080022452A (ko) * | 2006-09-06 | 2008-03-11 | 삼성전자주식회사 | Pop 패키지 및 그의 제조 방법 |
US8486979B2 (en) * | 2006-12-12 | 2013-07-16 | Abbvie Inc. | 1,2,4 oxadiazole compounds and methods of use thereof |
DK2481410T3 (en) * | 2007-01-31 | 2016-10-24 | Bial - Portela & Ca S A | Nitrocatecholderivater as COMT inhibitors administered in a specific dosage regimen |
-
2009
- 2009-02-27 EP EP09714442A patent/EP2259777A2/en not_active Withdrawn
- 2009-02-27 CN CN200980107030XA patent/CN101959504A/zh active Pending
- 2009-02-27 MX MX2010009043A patent/MX2010009043A/es not_active Application Discontinuation
- 2009-02-27 KR KR1020107021639A patent/KR20100126452A/ko not_active Application Discontinuation
- 2009-02-27 AU AU2009217865A patent/AU2009217865A1/en not_active Abandoned
- 2009-02-27 JP JP2010548634A patent/JP2011513301A/ja not_active Withdrawn
- 2009-02-27 BR BRPI0908340A patent/BRPI0908340A2/pt not_active IP Right Cessation
- 2009-02-27 US US12/920,025 patent/US20110014282A1/en not_active Abandoned
- 2009-02-27 WO PCT/PT2009/000009 patent/WO2009108077A2/en active Application Filing
- 2009-02-27 CA CA2715802A patent/CA2715802A1/en not_active Abandoned
- 2009-03-02 AR ARP090100726A patent/AR070731A1/es unknown
-
2010
- 2010-08-09 IL IL207512A patent/IL207512A0/en unknown
Also Published As
Publication number | Publication date |
---|---|
AU2009217865A1 (en) | 2009-09-03 |
US20110014282A1 (en) | 2011-01-20 |
KR20100126452A (ko) | 2010-12-01 |
WO2009108077A3 (en) | 2010-04-29 |
CA2715802A1 (en) | 2009-09-03 |
CN101959504A (zh) | 2011-01-26 |
BRPI0908340A2 (pt) | 2018-12-26 |
IL207512A0 (en) | 2010-12-30 |
EP2259777A2 (en) | 2010-12-15 |
WO2009108077A2 (en) | 2009-09-03 |
JP2011513301A (ja) | 2011-04-28 |
MX2010009043A (es) | 2010-10-25 |
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