AR070368A2 - PROCEDURE FOR THE PREPARATION OF A VACCINE COMPOSITION THAT INCLUDES AN IMMUNOSTIMULATING AN ANTIGEN AND A METAL SALT AND USE OF SUCH COMPOSITION TO PREPARE A MEDICINAL PRODUCT. VACCINE COMPOSITION - Google Patents

PROCEDURE FOR THE PREPARATION OF A VACCINE COMPOSITION THAT INCLUDES AN IMMUNOSTIMULATING AN ANTIGEN AND A METAL SALT AND USE OF SUCH COMPOSITION TO PREPARE A MEDICINAL PRODUCT. VACCINE COMPOSITION

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Publication number
AR070368A2
AR070368A2 ARP090100505A AR070368A2 AR 070368 A2 AR070368 A2 AR 070368A2 AR P090100505 A ARP090100505 A AR P090100505A AR 070368 A2 AR070368 A2 AR 070368A2
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AR
Argentina
Prior art keywords
vaccine composition
composition
metal salt
antigen
preparation
Prior art date
Application number
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Spanish (es)
Original Assignee
Smithkline Beecham Biolog
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Smithkline Beecham Biolog filed Critical Smithkline Beecham Biolog
Priority to ARP090100505 priority Critical patent/AR070368A2/en
Publication of AR070368A2 publication Critical patent/AR070368A2/en

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  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Reivindicacion 1: Un procedimiento para la preparacion de una composicion de vacuna que comprende un inmunoestimulante que es monofosforil lípido A o un derivado del mismo o un oligonucleotido que contiene un CpG, un antígeno y una sal metálica, dicho proceso caracterizado porque comprende: a) absorber el antígeno sobre una primera partícula de sal metálica; b) absorber el inmunoestimulante sobre una segunda partícula de sal metálica; y c) mezclar los productos de los pasos (a) y (b). Reivindicacion 6: Una composicion de vacuna caracterizada porque se obtiene mediante el proceso de cualquiera de las reivindicaciones 1 a 5. Reivindicacion 7: Uso de una composicion de vacuna de acuerdo con cualquiera de las reivindicaciones 1 a 5, caracterizado porque es para preparar un medicamento util para el tratamiento inmunoterapéutico de infecciones virales, bacterianas, de parásitos, alergia o cáncer.Claim 1: A process for the preparation of a vaccine composition comprising an immunostimulant that is monophosphoryl lipid A or a derivative thereof or an oligonucleotide containing a CpG, an antigen and a metal salt, said process characterized in that it comprises: a) absorb the antigen on a first metal salt particle; b) absorb the immunostimulant on a second metal salt particle; and c) mix the products of steps (a) and (b). Claim 6: A vaccine composition characterized in that it is obtained by the process of any of claims 1 to 5. Claim 7: Use of a vaccine composition according to any of claims 1 to 5, characterized in that it is for preparing a medicament Useful for the immunotherapeutic treatment of viral, bacterial, parasite, allergy or cancer infections.

ARP090100505 2009-02-12 2009-02-12 PROCEDURE FOR THE PREPARATION OF A VACCINE COMPOSITION THAT INCLUDES AN IMMUNOSTIMULATING AN ANTIGEN AND A METAL SALT AND USE OF SUCH COMPOSITION TO PREPARE A MEDICINAL PRODUCT. VACCINE COMPOSITION AR070368A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
ARP090100505 AR070368A2 (en) 2009-02-12 2009-02-12 PROCEDURE FOR THE PREPARATION OF A VACCINE COMPOSITION THAT INCLUDES AN IMMUNOSTIMULATING AN ANTIGEN AND A METAL SALT AND USE OF SUCH COMPOSITION TO PREPARE A MEDICINAL PRODUCT. VACCINE COMPOSITION

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ARP090100505 AR070368A2 (en) 2009-02-12 2009-02-12 PROCEDURE FOR THE PREPARATION OF A VACCINE COMPOSITION THAT INCLUDES AN IMMUNOSTIMULATING AN ANTIGEN AND A METAL SALT AND USE OF SUCH COMPOSITION TO PREPARE A MEDICINAL PRODUCT. VACCINE COMPOSITION

Publications (1)

Publication Number Publication Date
AR070368A2 true AR070368A2 (en) 2010-03-31

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ARP090100505 AR070368A2 (en) 2009-02-12 2009-02-12 PROCEDURE FOR THE PREPARATION OF A VACCINE COMPOSITION THAT INCLUDES AN IMMUNOSTIMULATING AN ANTIGEN AND A METAL SALT AND USE OF SUCH COMPOSITION TO PREPARE A MEDICINAL PRODUCT. VACCINE COMPOSITION

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AR (1) AR070368A2 (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10837018B2 (en) 2013-07-25 2020-11-17 Exicure, Inc. Spherical nucleic acid-based constructs as immunostimulatory agents for prophylactic and therapeutic use
US11123294B2 (en) 2014-06-04 2021-09-21 Exicure Operating Company Multivalent delivery of immune modulators by liposomal spherical nucleic acids for prophylactic or therapeutic applications
US11364304B2 (en) 2016-08-25 2022-06-21 Northwestern University Crosslinked micellar spherical nucleic acids

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10837018B2 (en) 2013-07-25 2020-11-17 Exicure, Inc. Spherical nucleic acid-based constructs as immunostimulatory agents for prophylactic and therapeutic use
US10894963B2 (en) 2013-07-25 2021-01-19 Exicure, Inc. Spherical nucleic acid-based constructs as immunostimulatory agents for prophylactic and therapeutic use
US11123294B2 (en) 2014-06-04 2021-09-21 Exicure Operating Company Multivalent delivery of immune modulators by liposomal spherical nucleic acids for prophylactic or therapeutic applications
US11957788B2 (en) 2014-06-04 2024-04-16 Exicure Operating Company Multivalent delivery of immune modulators by liposomal spherical nucleic acids for prophylactic or therapeutic applications
US11364304B2 (en) 2016-08-25 2022-06-21 Northwestern University Crosslinked micellar spherical nucleic acids

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