AR069960A1 - Formulacion farmaceutica de liberacion controlada y procedimiento para su preparacion - Google Patents

Formulacion farmaceutica de liberacion controlada y procedimiento para su preparacion

Info

Publication number
AR069960A1
AR069960A1 ARP080105697A ARP080105697A AR069960A1 AR 069960 A1 AR069960 A1 AR 069960A1 AR P080105697 A ARP080105697 A AR P080105697A AR P080105697 A ARP080105697 A AR P080105697A AR 069960 A1 AR069960 A1 AR 069960A1
Authority
AR
Argentina
Prior art keywords
pharmaceutical formulation
formulation according
preparation
alginate
glycogen
Prior art date
Application number
ARP080105697A
Other languages
English (en)
Inventor
Nicola Cazzolla
Leonardo Marchitto
Vincenzo Russo
Lorella Ragni
Elisa Liberati
Original Assignee
Acraf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Acraf filed Critical Acraf
Publication of AR069960A1 publication Critical patent/AR069960A1/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2009Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1611Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1629Organic macromolecular compounds
    • A61K9/1652Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/02Nasal agents, e.g. decongestants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Inorganic Chemistry (AREA)
  • Diabetes (AREA)
  • Pulmonology (AREA)
  • Otolaryngology (AREA)
  • Hematology (AREA)
  • Emergency Medicine (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Hospice & Palliative Care (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

La presente se refiere a una formulacion farmacéutica de liberacion controlada que comprende por lo menos un principio activo disperso en una matriz que comprende por lo menos un excipiente de liberacion retardada que comprende una asociacion de por lo menos un glucogeno y por lo menos un alginato con sales de metal alcalinotérreo y a un procedimiento para su preparacion. La solicitud se refiere asimismo a un excipiente de liberacion retardada que comprende una asociacion de por lo menos un glucogeno y por lo menos un alginato con sales de metal alcalinotérreo y al procedimiento para su preparacion, y a su utilizacion para la preparacion de formulaciones farmacéuticas de liberacion retardada. Reivindicacion 2: Formulacion farmacéutica segun la reivindicacion 1, en la que dicho glucogeno comprende menos del 1% en peso de azucares reductores. Reivindicacion 7: Formulacion farmacéutica segun cualquiera de las reivindicaciones anteriores, en la que una disolucion acuosa al 1% en peso de dicho alginato presenta una viscosidad dentro del intervalo comprendido entre 50 y 1500 cPs. Reivindicacion 12: Formulacion farmacéutica segun cualquiera de las reivindicaciones anteriores, en la que dicha sal de metal alcalinotérreo se selecciona de entre el grupo constituido por las sales solubles en agua de magnesio, calcio, estroncio y bario. Reivindicacion 18: Formulacion farmacéutica segun cualquiera de las reivindicaciones anteriores, en la que dicho principio activo se selecciona de entre el grupo constituido por analgésicos, antipiréticos, antibioticos, antihistamínicos, ansiolíticos, antiinflamatorios, antiácidos, vasodilatadores, vasoconstrictores, estimulantes, descongestionantes, anticoagulantes, antiarrítmicos, agentes hipoglucémicos, diuréticos, antidepresivos, antiasmáticos, antieméticos y agentes antihipotensores y antiespasmodicos. Reivindicacion 23: Formulacion farmacéutica segun la reivindicacion 22, en la que dicha forma farmacéutica comprende un recubrimiento entérico.
ARP080105697A 2007-12-28 2008-12-23 Formulacion farmaceutica de liberacion controlada y procedimiento para su preparacion AR069960A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP07425828 2007-12-28

Publications (1)

Publication Number Publication Date
AR069960A1 true AR069960A1 (es) 2010-03-03

Family

ID=39522216

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP080105697A AR069960A1 (es) 2007-12-28 2008-12-23 Formulacion farmaceutica de liberacion controlada y procedimiento para su preparacion

Country Status (21)

Country Link
US (1) US8840923B2 (es)
EP (1) EP2234607B1 (es)
JP (1) JP5416716B2 (es)
KR (1) KR101561571B1 (es)
CN (1) CN101909608B (es)
AR (1) AR069960A1 (es)
AT (1) ATE518530T1 (es)
AU (1) AU2008342571B2 (es)
BR (1) BRPI0821454B8 (es)
CA (1) CA2708400C (es)
DK (1) DK2234607T3 (es)
EA (1) EA018975B1 (es)
ES (1) ES2369868T3 (es)
GE (1) GEP20125636B (es)
HK (1) HK1145284A1 (es)
IL (1) IL206124A (es)
PL (1) PL2234607T3 (es)
PT (1) PT2234607E (es)
SI (1) SI2234607T1 (es)
UA (1) UA98684C2 (es)
WO (1) WO2009083561A1 (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2010206221B2 (en) 2009-01-23 2016-07-14 Aziende Chimiche Riunite Angelini Francesco A.C.R.A.F. S.P.A. Controlled release pharmaceutical or food formulation and process for its preparation
WO2011015509A1 (en) * 2009-08-03 2011-02-10 Aziende Chimiche Riunite Angelini Francesco A.C.R.A.F. S.P.A. Food formulation comprising glycogen
WO2014172785A1 (en) * 2013-04-26 2014-10-30 Mirexus Biotechnologies Inc. Monodisperse glycogen and phytoglycogen nanoparticles and use thereof as additives in cosmetics, pharmaceuticals, and food products
CN106137977B (zh) * 2015-04-28 2019-12-13 浙江普利药业有限公司 海参多糖肠溶微丸及其制备方法
ITUB20152290A1 (it) * 2015-07-17 2017-01-17 Laboratori Baldacci Spa Prodotto a base di ferro bisglicinato chelato e acido alginico e/o suoi sali idrosolubili, sue formulazioni ed suoi usi farmaceutici
US11865099B2 (en) 2015-07-17 2024-01-09 Laboratori Baldacci S.P.A. Product based on iron bis-glycinate chelate and alginic acid and/or water-soluble salts thereof, formulations thereof, and pharmaceutical uses thereof
US20190038542A1 (en) * 2016-02-08 2019-02-07 Mirexus Biotechnologies Inc. Moisturizing personal care compositions comprising monodisperse phytoglycogen nanoparticles and a further polysaccharide

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3640741A (en) * 1970-02-24 1972-02-08 Hollister Inc Composition containing gel
DE2062715C3 (de) * 1970-12-19 1974-03-21 Efeka Friedrich & Kaufmann Arzneimittelfabrik, 3000 Hannover Verfahren zur Herstellung von oral applizierbaren Arzneimittelzubereitungen mit protrahierter Wirkstoffabgabe und Arzneimittelzubereitung
DE3583799D1 (de) * 1985-01-11 1991-09-19 Abbott Lab Ltd Feste zubereitung mit langsamer freisetzung.
JPS62178505A (ja) 1986-02-03 1987-08-05 Maruzen Kasei Kk 化粧料
JPS63290809A (ja) 1987-05-25 1988-11-28 Noebia:Kk ***用化粧料
CA2041774C (en) * 1990-11-27 1994-04-19 Mircea A. Mateescu Use of cross-linked amylose as a matrix for the slow release of biologically active compounds
IT1255488B (it) * 1992-08-04 1995-11-06 Angelini Francesco Ist Ricerca Polisaccaridi del glicogeno
US5705190A (en) * 1995-12-19 1998-01-06 Abbott Laboratories Controlled release formulation for poorly soluble basic drugs
US5807575A (en) 1997-02-14 1998-09-15 Rougier Inc. Manufacture of cross-linked amylose useful as a excipient for control release of active compounds
IT1298758B1 (it) 1998-03-19 2000-02-02 Angelini Ricerche Spa Soluzione umettante e lubrificante per uso oftalmico
US6607748B1 (en) * 2000-06-29 2003-08-19 Vincent Lenaerts Cross-linked high amylose starch for use in controlled-release pharmaceutical formulations and processes for its manufacture
AU2001227030A1 (en) * 2000-11-22 2002-06-03 Lupin Laboratories Limited Pharmaceutical composition for controlled release of an active ingredient
WO2004096127A2 (en) * 2003-04-25 2004-11-11 Kos Life Sciences, Inc. Formation of strong superporous hydrogels
US20060067917A1 (en) * 2004-09-20 2006-03-30 Athanassios Sambanis Insulin delivery system
US7687608B2 (en) * 2005-10-19 2010-03-30 Smartcells, Inc. Methods for reducing the mitogenicity of lectin compositions

Also Published As

Publication number Publication date
SI2234607T1 (sl) 2011-11-30
HK1145284A1 (en) 2011-04-15
DK2234607T3 (da) 2011-11-21
AU2008342571A1 (en) 2009-07-09
IL206124A0 (en) 2010-11-30
CN101909608B (zh) 2013-01-23
EA018975B1 (ru) 2013-12-30
US8840923B2 (en) 2014-09-23
BRPI0821454A2 (pt) 2015-06-16
PL2234607T3 (pl) 2011-12-30
BRPI0821454B1 (pt) 2020-01-28
ES2369868T3 (es) 2011-12-07
EA201070806A1 (ru) 2010-12-30
WO2009083561A1 (en) 2009-07-09
ATE518530T1 (de) 2011-08-15
CN101909608A (zh) 2010-12-08
IL206124A (en) 2013-01-31
UA98684C2 (uk) 2012-06-11
JP5416716B2 (ja) 2014-02-12
KR101561571B1 (ko) 2015-10-19
BRPI0821454B8 (pt) 2021-05-25
GEP20125636B (en) 2012-09-10
CA2708400A1 (en) 2009-07-09
AU2008342571B2 (en) 2014-03-13
EP2234607A1 (en) 2010-10-06
JP2011519820A (ja) 2011-07-14
CA2708400C (en) 2016-02-02
PT2234607E (pt) 2011-09-30
KR20100099728A (ko) 2010-09-13
EP2234607B1 (en) 2011-08-03
US20100255083A1 (en) 2010-10-07

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