AR069885A1 - Metodos para producir el virus de estomatitis vesicular (vsv) atenuado en un cultivo celular y para mejorar el empaque del vsv de propagacion defectuosa, composicion inmunogenica, celula aislada y secuencia de control transcripcional - Google Patents
Metodos para producir el virus de estomatitis vesicular (vsv) atenuado en un cultivo celular y para mejorar el empaque del vsv de propagacion defectuosa, composicion inmunogenica, celula aislada y secuencia de control transcripcionalInfo
- Publication number
- AR069885A1 AR069885A1 ARP080105638A ARP080105638A AR069885A1 AR 069885 A1 AR069885 A1 AR 069885A1 AR P080105638 A ARP080105638 A AR P080105638A AR P080105638 A ARP080105638 A AR P080105638A AR 069885 A1 AR069885 A1 AR 069885A1
- Authority
- AR
- Argentina
- Prior art keywords
- vsv
- cell
- produce
- pack
- vesicular stomatitis
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2510/00—Genetically modified cells
- C12N2510/02—Cells for production
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/20011—Rhabdoviridae
- C12N2760/20211—Vesiculovirus, e.g. vesicular stomatitis Indiana virus
- C12N2760/20251—Methods of production or purification of viral material
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/20011—Rhabdoviridae
- C12N2760/20211—Vesiculovirus, e.g. vesicular stomatitis Indiana virus
- C12N2760/20251—Methods of production or purification of viral material
- C12N2760/20252—Methods of production or purification of viral material relating to complementing cells and packaging systems for producing virus or viral particles
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Immunology (AREA)
- Virology (AREA)
- General Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
Un método para producir el virus de estomatitis vesicular de propagacion defectuosa (VSV). El método involucra proporcionar una célula que incluye un gen G VSV optimizado, en donde la expresion de la proteína G VSV del gen G VSV optimizado es inducible; e inducir la célula para expresar la proteína G VSV del gen G VSV optimizado. El método también involucra infectar la célula inducida con un VSV atenuado; hacer crecer las células en el cultivo; y recuperar el VSV atenuado del cultivo.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US1535307P | 2007-12-20 | 2007-12-20 |
Publications (1)
Publication Number | Publication Date |
---|---|
AR069885A1 true AR069885A1 (es) | 2010-02-24 |
Family
ID=40418917
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP080105638A AR069885A1 (es) | 2007-12-20 | 2008-12-19 | Metodos para producir el virus de estomatitis vesicular (vsv) atenuado en un cultivo celular y para mejorar el empaque del vsv de propagacion defectuosa, composicion inmunogenica, celula aislada y secuencia de control transcripcional |
Country Status (8)
Country | Link |
---|---|
US (1) | US20090162321A1 (es) |
EP (1) | EP2225264A1 (es) |
JP (1) | JP2011507514A (es) |
AR (1) | AR069885A1 (es) |
AU (1) | AU2008343919B2 (es) |
CA (1) | CA2710166A1 (es) |
CL (1) | CL2008003821A1 (es) |
WO (1) | WO2009085172A1 (es) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2533345T3 (es) | 2009-06-08 | 2015-04-09 | The University Of Western Ontario | Diferentes serotipos del virus de la estomatitis vesicular como vectores de expresión para regímenes de inmunización |
US9610346B2 (en) | 2012-03-23 | 2017-04-04 | International Aids Vaccine Initiative | Recombinant viral vectors |
EP3681523A4 (en) * | 2017-09-15 | 2021-12-29 | The Ohio State Innovation Foundation | Vaccines and methods of making and using vaccines for prevention of respiratory syncytial virus (rsv) infections |
US20200299686A1 (en) * | 2017-10-02 | 2020-09-24 | Georgia Tech Research Corporation | Methods and Compositions for Engineering Synthetic Bioswitches for Remote Control of Biological Activity |
CN109750006A (zh) * | 2019-01-14 | 2019-05-14 | 青岛农业大学 | 一种犬瘟热病毒复制缺陷毒株及其构建方法 |
CN115725657B (zh) * | 2022-09-16 | 2024-06-04 | 中国科学院广州生物医药与健康研究院 | 一种节段化的水泡性口炎病毒载体及其制备方法和应用 |
CN117051040A (zh) * | 2023-08-15 | 2023-11-14 | 北京百普赛斯生物科技股份有限公司 | Vsv△g复制缺陷型病毒制备及应用 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5168062A (en) * | 1985-01-30 | 1992-12-01 | University Of Iowa Research Foundation | Transfer vectors and microorganisms containing human cytomegalovirus immediate-early promoter-regulatory DNA sequence |
EP1005535B1 (en) * | 1997-05-02 | 2015-11-11 | The Uab Research Foundation | Attenuation of negative stranded rna viruses by rearrangement of their genes and uses thereof |
US6596529B1 (en) * | 1997-05-02 | 2003-07-22 | Uab Research Foundation | Manipulation of negative stranded RNA viruses by rearrangement of their genes and uses thereof |
WO2001038488A2 (en) * | 1999-11-23 | 2001-05-31 | Mayo Foundation For Medical Education And Research | Gene expression by positive feedback activation of a cell type-specific promoter |
JP2007500017A (ja) * | 2003-06-09 | 2007-01-11 | ワイス | cDNAからの非分節型、ネガティブ鎖RNAウイルスの回収のための改良方法 |
US8008268B2 (en) * | 2006-07-25 | 2011-08-30 | Merial Limited | Vaccines against vesicular stomatitis |
-
2008
- 2008-12-16 US US12/335,778 patent/US20090162321A1/en not_active Abandoned
- 2008-12-18 JP JP2010539474A patent/JP2011507514A/ja active Pending
- 2008-12-18 AU AU2008343919A patent/AU2008343919B2/en not_active Ceased
- 2008-12-18 EP EP08867848A patent/EP2225264A1/en not_active Withdrawn
- 2008-12-18 CA CA2710166A patent/CA2710166A1/en not_active Abandoned
- 2008-12-18 WO PCT/US2008/013817 patent/WO2009085172A1/en active Application Filing
- 2008-12-19 AR ARP080105638A patent/AR069885A1/es unknown
- 2008-12-19 CL CL2008003821A patent/CL2008003821A1/es unknown
Also Published As
Publication number | Publication date |
---|---|
WO2009085172A1 (en) | 2009-07-09 |
CA2710166A1 (en) | 2009-07-09 |
CL2008003821A1 (es) | 2009-04-03 |
US20090162321A1 (en) | 2009-06-25 |
AU2008343919A1 (en) | 2009-07-09 |
JP2011507514A (ja) | 2011-03-10 |
AU2008343919B2 (en) | 2013-01-17 |
EP2225264A1 (en) | 2010-09-08 |
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