AR068925A1 - Un proceso mejorado para preparar un derivado de 2,4. - tiazolidindiona - Google Patents
Un proceso mejorado para preparar un derivado de 2,4. - tiazolidindionaInfo
- Publication number
- AR068925A1 AR068925A1 ARP080104553A ARP080104553A AR068925A1 AR 068925 A1 AR068925 A1 AR 068925A1 AR P080104553 A ARP080104553 A AR P080104553A AR P080104553 A ARP080104553 A AR P080104553A AR 068925 A1 AR068925 A1 AR 068925A1
- Authority
- AR
- Argentina
- Prior art keywords
- solvates
- rosiglitazone
- prepare
- maleate
- rosiglitazone maleate
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Diabetes (AREA)
- General Chemical & Material Sciences (AREA)
- Emergency Medicine (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Endocrinology (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
La presente se refiere a un proceso para preparar maleato de rosifglitazona con un bajo contenido de subproductos no deseados, el compuesto y su uso para preparar medicamentos para el tratamiento de la diabetes. Reivindicacion 1: Un proceso para preparar maleato de rosiglitazona y/o sus solvatos, el cual proporciona maleato de rosiglitazona y/o sus solvatos con una cantidad mínima de compuesto de Formula 2, comprendiendo dicho proceso las etapas de: (i) hacer reaccionar la rosiglitazona con ácido maleico en un solvente de alcohol C2-5 o mezclas de los mismos a una temperatura no superior a 78°C, (ii) opcionalmente, purificar el maleato de rosiglitazona obtenido y/o sus solvatos, y (iii) secar el maleato de rosiglitazona obtenido y/o sus solvatos.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US98046607P | 2007-10-17 | 2007-10-17 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR068925A1 true AR068925A1 (es) | 2009-12-16 |
Family
ID=40567867
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP080104553A AR068925A1 (es) | 2007-10-17 | 2008-10-17 | Un proceso mejorado para preparar un derivado de 2,4. - tiazolidindiona |
Country Status (2)
| Country | Link |
|---|---|
| AR (1) | AR068925A1 (es) |
| WO (1) | WO2009050595A2 (es) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102863436B (zh) * | 2012-06-19 | 2018-02-09 | 重庆医科大学 | 噻唑烷二酮类衍生物及其制备和用途 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5741803A (en) * | 1992-09-05 | 1998-04-21 | Smithkline Beecham Plc | Substituted thiazolidinedionle derivatives |
| DE06252444T8 (de) * | 2006-05-09 | 2009-03-19 | Teva Pharmaceutical Industries Ltd. | 2-N-{5-[[4-[2-(Methyl-2-pyridinylamino)-ethoxy]-phenyl]-methyl]-2,4-thiazolidindion}-bernsteinsäure, Verfahren zur Herstellung und Zusammensetzungen mit Rosiglitazonmaleat |
| US20070293546A1 (en) * | 2006-06-15 | 2007-12-20 | Srinivasula Reddy Maddula | Preparation of rosiglitazone and its salts |
-
2008
- 2008-10-17 WO PCT/IB2008/003821 patent/WO2009050595A2/en active Application Filing
- 2008-10-17 AR ARP080104553A patent/AR068925A1/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2009050595A3 (en) | 2009-07-30 |
| WO2009050595A2 (en) | 2009-04-23 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FB | Suspension of granting procedure |