AR068187A1 - Forma cristalina de un intermediario sintetico para la preparacion de un inhibidor de dpp-iv - Google Patents

Forma cristalina de un intermediario sintetico para la preparacion de un inhibidor de dpp-iv

Info

Publication number
AR068187A1
AR068187A1 ARP080102995A ARP080102995A AR068187A1 AR 068187 A1 AR068187 A1 AR 068187A1 AR P080102995 A ARP080102995 A AR P080102995A AR P080102995 A ARP080102995 A AR P080102995A AR 068187 A1 AR068187 A1 AR 068187A1
Authority
AR
Argentina
Prior art keywords
inhibitor
preparation
dpp
crystal form
crystalline form
Prior art date
Application number
ARP080102995A
Other languages
English (en)
Inventor
Zhen-Ping Wu
Original Assignee
Phenomix Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Phenomix Corp filed Critical Phenomix Corp
Publication of AR068187A1 publication Critical patent/AR068187A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
    • C07F5/02—Boron compounds
    • C07F5/025—Boronic and borinic acid compounds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

La invencion provee una forma cristalina de un intermediario sintético de utilidad en la preparacion de un inhibidor de DPP-IV, un método de preparacion de la forma cristalina del intermediario y un método de uso de la forma cristalina del intermediario en la preparacion del inhibidor. Utiles para el tratamiento de la diabetes mellitus. Reivindicacion 1: Una forma cristalina de un compuesto de la formula (1).
ARP080102995A 2007-07-12 2008-07-11 Forma cristalina de un intermediario sintetico para la preparacion de un inhibidor de dpp-iv AR068187A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US95922607P 2007-07-12 2007-07-12

Publications (1)

Publication Number Publication Date
AR068187A1 true AR068187A1 (es) 2009-11-11

Family

ID=40229094

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP080102995A AR068187A1 (es) 2007-07-12 2008-07-11 Forma cristalina de un intermediario sintetico para la preparacion de un inhibidor de dpp-iv

Country Status (8)

Country Link
US (1) US20100204484A1 (es)
EP (1) EP2175727A4 (es)
AR (1) AR068187A1 (es)
CA (1) CA2692758A1 (es)
CL (1) CL2008002044A1 (es)
MX (1) MX2010000501A (es)
TW (1) TW200927144A (es)
WO (1) WO2009009751A1 (es)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UY32030A (es) 2008-08-06 2010-03-26 Boehringer Ingelheim Int "tratamiento para diabetes en pacientes inapropiados para terapia con metformina"
JP5906086B2 (ja) 2008-08-15 2016-04-20 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング Ｆａｂ関連疾患の治療に用いるためのプリン誘導体
TW201036975A (en) 2009-01-07 2010-10-16 Boehringer Ingelheim Int Treatment for diabetes in patients with inadequate glycemic control despite metformin therapy
TWI466672B (zh) 2009-01-29 2015-01-01 Boehringer Ingelheim Int 小兒科病人糖尿病之治療
CN106177958A (zh) 2009-02-13 2016-12-07 勃林格殷格翰国际有限公司 包含dpp‑4抑制剂(利拉列汀)任选地组合其它抗糖尿病药的抗糖尿病药物
JP2013512229A (ja) 2009-11-27 2013-04-11 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 遺伝子型が同定された糖尿病患者のリナグリプチン等のｄｄｐ−ｉｖ阻害薬による治療
WO2011113947A1 (en) 2010-03-18 2011-09-22 Boehringer Ingelheim International Gmbh Combination of a gpr119 agonist and the dpp-iv inhibitor linagliptin for use in the treatment of diabetes and related conditions
NZ602921A (en) 2010-05-05 2016-01-29 Boehringer Ingelheim Int Combination therapy comprising the administration of a glp-1 receptor agonist and a ddp-4 inhibitor
MX2012014247A (es) 2010-06-24 2013-01-18 Boehringer Ingelheim Int Terapia para la diabetes.
WO2012170702A1 (en) 2011-06-08 2012-12-13 Arena Pharmaceuticals, Inc. Modulators of the gpr119 receptor and the treatment of disorders related thereto
WO2013174767A1 (en) 2012-05-24 2013-11-28 Boehringer Ingelheim International Gmbh A xanthine derivative as dpp -4 inhibitor for use in modifying food intake and regulating food preference

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3496163A (en) * 1965-02-08 1970-02-17 Upjohn Co 7-halo-7-deoxylincomycins and process for preparing the same
US5329012A (en) * 1987-10-29 1994-07-12 The Research Foundation Of State University Of New York Bis(acyloxmethyl)imidazole compounds
US20100087658A1 (en) * 1996-08-06 2010-04-08 Phenomix Corporation Methods and intermediates for synthesis of selective dpp-iv inhibitors
US20040077605A1 (en) * 2001-06-20 2004-04-22 Salvati Mark E. Fused heterocyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function
US7317109B2 (en) * 2003-11-12 2008-01-08 Phenomix Corporation Pyrrolidine compounds and methods for selective inhibition of dipeptidyl peptidase-IV
US7576121B2 (en) * 2003-11-12 2009-08-18 Phenomix Corporation Pyrrolidine compounds and methods for selective inhibition of dipeptidyl peptidase-IV
EP1919485A4 (en) * 2005-08-01 2011-03-23 Phenomix Corp METHOD FOR PRODUCING HETEROCYCLIC BORONIC ACIDS AND ITS DERIVATIVES
WO2007038676A2 (en) * 2005-09-28 2007-04-05 Teva Pharmaceutical Industries Ltd. Polymorphic forms of ladostigil tartrate

Also Published As

Publication number Publication date
US20100204484A1 (en) 2010-08-12
TW200927144A (en) 2009-07-01
EP2175727A1 (en) 2010-04-21
MX2010000501A (es) 2011-05-25
WO2009009751A1 (en) 2009-01-15
CL2008002044A1 (es) 2009-01-16
EP2175727A4 (en) 2011-05-25
CA2692758A1 (en) 2009-01-15

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