AR055054A1 - Cristales formados de clorhidrato de (((2r)-7-(2,6-diclorofenil)-5-fluoro-2,3- dihidro-1-benzofurano-2-il) metil ) amina - Google Patents
Cristales formados de clorhidrato de (((2r)-7-(2,6-diclorofenil)-5-fluoro-2,3- dihidro-1-benzofurano-2-il) metil ) aminaInfo
- Publication number
- AR055054A1 AR055054A1 ARP060101596A ARP060101596A AR055054A1 AR 055054 A1 AR055054 A1 AR 055054A1 AR P060101596 A ARP060101596 A AR P060101596A AR P060101596 A ARP060101596 A AR P060101596A AR 055054 A1 AR055054 A1 AR 055054A1
- Authority
- AR
- Argentina
- Prior art keywords
- dihydro
- fluoro
- methyl
- diclorophenyl
- amina
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- C07D307/81—Radicals substituted by nitrogen atoms not forming part of a nitro radical
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Psychiatry (AREA)
- Addiction (AREA)
- Pain & Pain Management (AREA)
- Child & Adolescent Psychology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Hospice & Palliative Care (AREA)
- Anesthesiology (AREA)
- Gynecology & Obstetrics (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Furan Compounds (AREA)
Abstract
Así como las composiciones, los procesos de preparacion, y las aplicaciones de estas. Reivindicacion 1: Un polimorfo cristalina (Forma I) de clorhidrato de {[(2R)-7-(2,6-diclorofenil)-5-fluoro-2,3-dihidro-1-benzo-furano-2-il]metil} amina, caracterizado porque tiene un patron de difraccion de polvo de rayos X comprendiendo un peak característico, en términos de 2 theta, en alrededor 10,2° y por lo menos un peak característico, en términos de 2 theta, seleccionado alrededor de 27,0° y sobre 25,8°.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US67431805P | 2005-04-22 | 2005-04-22 |
Publications (1)
Publication Number | Publication Date |
---|---|
AR055054A1 true AR055054A1 (es) | 2007-08-01 |
Family
ID=36609610
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP060101596A AR055054A1 (es) | 2005-04-22 | 2006-04-21 | Cristales formados de clorhidrato de (((2r)-7-(2,6-diclorofenil)-5-fluoro-2,3- dihidro-1-benzofurano-2-il) metil ) amina |
Country Status (13)
Country | Link |
---|---|
US (1) | US20060252825A1 (es) |
EP (1) | EP1879875A1 (es) |
JP (1) | JP2008538581A (es) |
CN (1) | CN101163689A (es) |
AR (1) | AR055054A1 (es) |
AU (1) | AU2006239897A1 (es) |
BR (1) | BRPI0610785A2 (es) |
CA (1) | CA2603900A1 (es) |
GT (1) | GT200600158A (es) |
MX (1) | MX2007013179A (es) |
PE (1) | PE20061319A1 (es) |
TW (1) | TW200716583A (es) |
WO (1) | WO2006116218A1 (es) |
Families Citing this family (23)
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US7435837B2 (en) * | 2003-10-24 | 2008-10-14 | Wyeth | Dihydrobenzofuranyl alkanamine derivatives and methods for using same |
US20050261347A1 (en) * | 2003-10-24 | 2005-11-24 | Wyeth | Dihydrobenzofuranyl alkanamine derivatives and methods for using same |
GT200500296A (es) * | 2004-10-21 | 2006-10-02 | Sintesis asimetrica de derivados del dehidrobenzofurano | |
GT200500297A (es) * | 2004-10-21 | 2006-10-27 | Sintesis asimetrica de dehidrobenzofuranos sustituidos | |
BRPI0610037A2 (pt) * | 2005-04-22 | 2010-05-25 | Wyeth Corp | derivados de dihidrobenzofurano e uso dos mesmos |
WO2006116150A1 (en) * | 2005-04-22 | 2006-11-02 | Wyeth | Dihydrobenzofuran derivatives and uses thereof |
MX2007013026A (es) * | 2005-04-22 | 2008-01-11 | Wyeth Corp | Combinaciones terapeuticas para el tratamiento o prevencion de trastornos psicoticos. |
CN101218223A (zh) * | 2005-04-22 | 2008-07-09 | 惠氏公司 | 苯并二烷和苯并二氧戊环衍生物及其应用 |
CA2605117A1 (en) * | 2005-04-22 | 2006-11-02 | Wyeth | Treatment of pain |
EP1871355A1 (en) * | 2005-04-22 | 2008-01-02 | Wyeth | New therapeutic combianations for the treatment or prevention of depression |
EP1871358A1 (en) * | 2005-04-22 | 2008-01-02 | Wyeth | Benzofuranyl alkanamine derivatives and uses thereof as 5-ht2c agonists |
WO2006116136A1 (en) * | 2005-04-22 | 2006-11-02 | Wyeth | Dihydrobenzofuran derivatives and uses thereof |
RU2007139541A (ru) * | 2005-04-22 | 2009-05-27 | Вайет (Us) | Производные хромана и хромена и их применение |
AU2006239941A1 (en) * | 2005-04-24 | 2006-11-02 | Wyeth | Methods for modulating bladder function |
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RS55559B1 (sr) | 2007-12-07 | 2017-05-31 | Vertex Pharma | Čvrste forme 3-(6-(1-(2,2-difluorobenzo[d][1,3]dioksol-5-il)ciklopropankarboksamido)-3-metilpiridin-2-il) benzoeve kiseline |
IT1397912B1 (it) * | 2010-01-28 | 2013-02-04 | Chemi Spa | Nuovo polimorfo dell'estere 6-dietilamminometil-2-naftilico dell'acido 4-idrossicarbamoil-fenil-carbammico cloridrato. |
NZ602838A (en) | 2010-04-07 | 2015-06-26 | Vertex Pharma | Pharmaceutical compositions of 3-(6-(1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl) cyclopropanecarboxamido)-3-methylpyridin-2-yl)benzoic acid and administration thereof |
JP6963896B2 (ja) | 2013-11-12 | 2021-11-10 | バーテックス ファーマシューティカルズ インコーポレイテッドVertex Pharmaceuticals Incorporated | Cftr媒介性疾患の処置のための医薬組成物を調製する方法 |
JPWO2019131902A1 (ja) | 2017-12-27 | 2020-12-10 | 武田薬品工業株式会社 | 腹圧性尿失禁および便失禁の治療薬 |
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-
2006
- 2006-04-21 MX MX2007013179A patent/MX2007013179A/es unknown
- 2006-04-21 CA CA002603900A patent/CA2603900A1/en not_active Abandoned
- 2006-04-21 WO PCT/US2006/015309 patent/WO2006116218A1/en active Application Filing
- 2006-04-21 AU AU2006239897A patent/AU2006239897A1/en not_active Abandoned
- 2006-04-21 BR BRPI0610785A patent/BRPI0610785A2/pt not_active IP Right Cessation
- 2006-04-21 GT GT200600158A patent/GT200600158A/es unknown
- 2006-04-21 US US11/409,303 patent/US20060252825A1/en not_active Abandoned
- 2006-04-21 TW TW095114307A patent/TW200716583A/zh unknown
- 2006-04-21 JP JP2008507967A patent/JP2008538581A/ja active Pending
- 2006-04-21 AR ARP060101596A patent/AR055054A1/es not_active Application Discontinuation
- 2006-04-21 CN CNA2006800134372A patent/CN101163689A/zh active Pending
- 2006-04-21 PE PE2006000421A patent/PE20061319A1/es not_active Application Discontinuation
- 2006-04-21 EP EP06758520A patent/EP1879875A1/en not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
CA2603900A1 (en) | 2006-11-02 |
GT200600158A (es) | 2006-11-28 |
MX2007013179A (es) | 2008-01-16 |
AU2006239897A1 (en) | 2006-11-02 |
WO2006116218A1 (en) | 2006-11-02 |
EP1879875A1 (en) | 2008-01-23 |
TW200716583A (en) | 2007-05-01 |
CN101163689A (zh) | 2008-04-16 |
US20060252825A1 (en) | 2006-11-09 |
JP2008538581A (ja) | 2008-10-30 |
PE20061319A1 (es) | 2006-12-28 |
BRPI0610785A2 (pt) | 2016-09-13 |
WO2006116218A8 (en) | 2007-02-22 |
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