AR052142A1 - Perla recubierta enterica que comprende ixabepilona, y preparacion y administracion de la misma - Google Patents
Perla recubierta enterica que comprende ixabepilona, y preparacion y administracion de la mismaInfo
- Publication number
- AR052142A1 AR052142A1 ARP050104839A ARP050104839A AR052142A1 AR 052142 A1 AR052142 A1 AR 052142A1 AR P050104839 A ARP050104839 A AR P050104839A AR P050104839 A ARP050104839 A AR P050104839A AR 052142 A1 AR052142 A1 AR 052142A1
- Authority
- AR
- Argentina
- Prior art keywords
- enteric coated
- ixabepilona
- administration
- preparation
- same
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
- A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Abstract
Una perla recubierta entérica que comprende Ixabepilona, un compuesto que tiene una estructura de formula (1). También una cápsula que comprende una multitud de perlas recubiertas entéricas. Además, se describe un método de preparacion de la perla recubierta entérica y un método de tratamiento de cáncer u otras enfermedades proliferativas que usa la perla recubierta entérica.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US62897004P | 2004-11-18 | 2004-11-18 |
Publications (1)
Publication Number | Publication Date |
---|---|
AR052142A1 true AR052142A1 (es) | 2007-03-07 |
Family
ID=35976527
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP050104839A AR052142A1 (es) | 2004-11-18 | 2005-11-17 | Perla recubierta enterica que comprende ixabepilona, y preparacion y administracion de la misma |
Country Status (26)
Country | Link |
---|---|
US (1) | US20060153917A1 (es) |
EP (2) | EP1817013B1 (es) |
JP (1) | JP2008520696A (es) |
KR (1) | KR20070084325A (es) |
CN (1) | CN101083978A (es) |
AR (1) | AR052142A1 (es) |
AT (1) | ATE397442T1 (es) |
AU (1) | AU2005306464A1 (es) |
BR (1) | BRPI0518286A2 (es) |
CA (1) | CA2588400A1 (es) |
DE (1) | DE602005007376D1 (es) |
DK (1) | DK1817013T3 (es) |
ES (1) | ES2306278T3 (es) |
HK (1) | HK1106713A1 (es) |
HR (1) | HRP20080349T3 (es) |
IL (1) | IL183116A0 (es) |
MX (1) | MX2007005763A (es) |
NO (1) | NO20072388L (es) |
PE (1) | PE20061058A1 (es) |
PL (1) | PL1817013T3 (es) |
PT (1) | PT1817013E (es) |
RU (1) | RU2349319C1 (es) |
SI (1) | SI1817013T1 (es) |
TW (1) | TW200631609A (es) |
WO (1) | WO2006055740A1 (es) |
ZA (1) | ZA200703955B (es) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101091725A (zh) * | 2006-06-23 | 2007-12-26 | 天津天士力制药股份有限公司 | 一种中药颗粒及其制备方法 |
US20110217426A1 (en) * | 2010-03-04 | 2011-09-08 | Perry Stephen C | Enteric coating composition |
EP2544541B1 (en) * | 2010-03-12 | 2014-10-08 | Genzyme Corporation | Combination therapy for treating breast cancer |
WO2012047802A2 (en) * | 2010-10-01 | 2012-04-12 | The Johns Hopkins University | Systems and methods for high-throughput microfluidic bead production |
US8808736B2 (en) | 2011-02-11 | 2014-08-19 | Zx Pharma, Llc | Enteric coated multiparticulate controlled release peppermint oil composition and related methods |
KR101809305B1 (ko) | 2011-02-11 | 2017-12-14 | 제트엑스 파마 엘엘씨 | 다중미립자 l-멘톨 제제 및 관련 방법 |
US8911780B2 (en) | 2011-02-11 | 2014-12-16 | Zx Pharma, Llc | Multiparticulate L-menthol formulations and related methods |
RS58325B1 (sr) | 2013-04-23 | 2019-03-29 | Zx Pharma Llc | Enterosolventno obloženi višečestični preparat sa proteinskom sub-oblogom |
Family Cites Families (46)
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US4713246A (en) * | 1984-03-19 | 1987-12-15 | Bristol-Myers Company | Etoposide oral dosage form |
US6537579B1 (en) * | 1993-02-22 | 2003-03-25 | American Bioscience, Inc. | Compositions and methods for administration of pharmacologically active compounds |
DE59609305D1 (de) * | 1995-11-17 | 2002-07-11 | Biotechnolog Forschung Gmbh | Epothilon-Derivate und deren Herstellung |
JP4090529B2 (ja) * | 1996-01-24 | 2008-05-28 | フロイント産業株式会社 | 乳糖の球形粒及びその製造方法 |
US6011029A (en) | 1996-02-26 | 2000-01-04 | Bristol-Myers Squibb Company | Inhibitors of farnesyl protein transferase |
CA2266519C (en) * | 1996-10-02 | 2007-01-23 | Novartis Ag | Pyrimidine derivatives and processes for the preparation thereof |
EP0941227B2 (de) * | 1996-11-18 | 2009-10-14 | Gesellschaft für biotechnologische Forschung mbH (GBF) | Epothilon d, dessen herstellung und dessen verwendung als cytostatisches mittel bzw. als pflanzenschutzmittel |
FR2759293B1 (fr) * | 1997-02-11 | 1999-04-30 | Ethypharm Lab Prod Ethiques | Microgranules contenant du cisplatine, procede de fabrication, preparation pharmaceutique et utilisation en polychimiotherapie ou en association avec une radiotherapie |
EP1201666A3 (de) * | 1997-02-25 | 2003-03-05 | Gesellschaft für biotechnologische Forschung mbH (GBF) | Seitenkettenmodifizierte Epothilone |
GB9801231D0 (en) | 1997-06-05 | 1998-03-18 | Merck & Co Inc | A method of treating cancer |
US6605599B1 (en) | 1997-07-08 | 2003-08-12 | Bristol-Myers Squibb Company | Epothilone derivatives |
US6040321A (en) | 1997-11-12 | 2000-03-21 | Bristol-Myers Squibb Company | Aminothiazole inhibitors of cyclin dependent kinases |
US6365749B1 (en) | 1997-12-04 | 2002-04-02 | Bristol-Myers Squibb Company | Process for the preparation of ring-opened epothilone intermediates which are useful for the preparation of epothilone analogs |
FR2775187B1 (fr) * | 1998-02-25 | 2003-02-21 | Novartis Ag | Utilisation de l'epothilone b pour la fabrication d'une preparation pharmaceutique antiproliferative et d'une composition comprenant l'epothilone b comme agent antiproliferatif in vivo |
US6380395B1 (en) * | 1998-04-21 | 2002-04-30 | Bristol-Myers Squibb Company | 12, 13-cyclopropane epothilone derivatives |
US6498257B1 (en) * | 1998-04-21 | 2002-12-24 | Bristol-Myers Squibb Company | 2,3-olefinic epothilone derivatives |
UA69413C2 (uk) * | 1998-05-22 | 2004-09-15 | Брістол-Майерс Сквібб Компані | Фармацевтична композиція, яка містить серцевину та ентеросолюбільну оболонку, фармацевтична композиція у вигляді сфероїдальних гранул, спосіб одержання сфероїдальних гранул та спосіб одержання фармацевтичної композиції |
US7122207B2 (en) * | 1998-05-22 | 2006-10-17 | Bristol-Myers Squibb Company | High drug load acid labile pharmaceutical composition |
DE19826988A1 (de) * | 1998-06-18 | 1999-12-23 | Biotechnolog Forschung Gmbh | Epothilon-Nebenkomponenten |
UA73092C2 (uk) * | 1998-07-17 | 2005-06-15 | Брістол-Майерс Сквібб Компані | Таблетка з ентеросолюбільним покриттям і спосіб її приготування |
US5997905A (en) * | 1998-09-04 | 1999-12-07 | Mcneil-Ppc | Preparation of pharmaceutically active particles |
ATE295151T1 (de) * | 1998-10-01 | 2005-05-15 | Powderject Res Ltd | Sprühbeschichtete mikropartikel für nadellose spritzen |
EE200100431A (et) * | 1999-02-18 | 2002-12-16 | Schering Aktiengesellschaft | 16-halogenoepotilooni derivaadid, nende valmistamismeetod ja farmatseutiline kasutamine |
HUP0200076A3 (en) * | 1999-02-22 | 2003-01-28 | Bristol Myers Squibb Co | C-21 modified epothilones, process for their preparation, pharmaceutical compositions containing them |
US6518421B1 (en) * | 2000-03-20 | 2003-02-11 | Bristol-Myers Squibb Company | Process for the preparation of epothilone analogs |
YU26102A (sh) * | 2000-08-09 | 2004-12-31 | Panacea Biotec Limited | Nove farmaceutske smese antituberkuloznih lekova i postupak za njihovo dobijanje |
UA75365C2 (en) * | 2000-08-16 | 2006-04-17 | Bristol Myers Squibb Co | Epothilone analog polymorph modifications, a method for obtaining thereof (variants), a pharmaceutical composition based thereon |
PL362225A1 (en) * | 2000-09-22 | 2004-10-18 | GESELLSCHAFT FüR BIOTECHNOLOGISCHE FORSCHUNG MBH (GBF) | Triazolo-epothilones |
ATE279552T1 (de) | 2000-09-26 | 2004-10-15 | Enthone Omi Deutschland Gmbh | Verfahren zur selektiven metallisierung dielektrischer materialien |
BRPI0206509B8 (pt) * | 2001-01-25 | 2021-05-25 | R Pharm Us Operating Llc | processo para formular, para administração parenteral, um análogo de epotilona, preparação farmacêutica, processo para formar uma composição farmacêutica para administração parental, composição farmacêutica e uso de um análogo de epotilona na preparação de uma composição farmacêutica para o tratamento de câncer |
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CA2440555A1 (en) * | 2001-03-14 | 2002-09-19 | Bristol-Myers Squibb Company | Combination of epothilone analogs and chemotherapeutic agents for the treatment of proliferative diseases |
EP1392664A4 (en) * | 2001-06-01 | 2005-01-26 | Bristol Myers Squibb Co | EPOTHILONE DERIVATIVES |
JP4645789B2 (ja) * | 2001-06-18 | 2011-03-09 | Jsr株式会社 | ネガ型感放射線性樹脂組成物 |
WO2003077903A1 (en) * | 2002-03-12 | 2003-09-25 | Bristol-Myers Squibb Company | C12-cyano epothilone derivatives |
ES2337134T3 (es) * | 2002-03-12 | 2010-04-21 | Bristol-Myers Squibb Company | Derivados de c3-ciano-epotilona. |
TW200403994A (en) * | 2002-04-04 | 2004-03-16 | Bristol Myers Squibb Co | Oral administration of EPOTHILONES |
TW200400191A (en) * | 2002-05-15 | 2004-01-01 | Bristol Myers Squibb Co | Pharmaceutical compositions and methods of using C-21 modified epothilone derivatives |
WO2003105828A1 (en) * | 2002-06-14 | 2003-12-24 | Bristol-Myers Squibb Company | Combination of epothilone analogs and chemotherapeutic agents for the treatment of proliferative diseases |
AU2003256157A1 (en) * | 2002-08-05 | 2004-02-23 | Dsm Ip Assets B.V. | Oral dosage forms of water insoluble drugs and methods of making the same |
EP1551425A4 (en) * | 2002-10-09 | 2006-09-20 | Kosan Biosciences Inc | THERAPEUTIC FORMULATIONS |
US20050171167A1 (en) * | 2003-11-04 | 2005-08-04 | Haby Thomas A. | Process and formulation containing epothilones and analogs thereof |
EP1824458A1 (en) * | 2004-11-18 | 2007-08-29 | Bristol-Myers Squibb Company | Enteric coated bead comprising epothilone or an epothilone analog, and preparation and administration thereof |
-
2005
- 2005-11-17 CN CNA2005800393851A patent/CN101083978A/zh active Pending
- 2005-11-17 US US11/281,855 patent/US20060153917A1/en not_active Abandoned
- 2005-11-17 EP EP05824194A patent/EP1817013B1/en active Active
- 2005-11-17 PT PT05824194T patent/PT1817013E/pt unknown
- 2005-11-17 CA CA002588400A patent/CA2588400A1/en not_active Abandoned
- 2005-11-17 DK DK05824194T patent/DK1817013T3/da active
- 2005-11-17 PE PE2005001348A patent/PE20061058A1/es not_active Application Discontinuation
- 2005-11-17 BR BRPI0518286-7A patent/BRPI0518286A2/pt not_active IP Right Cessation
- 2005-11-17 AR ARP050104839A patent/AR052142A1/es unknown
- 2005-11-17 PL PL05824194T patent/PL1817013T3/pl unknown
- 2005-11-17 JP JP2007543252A patent/JP2008520696A/ja not_active Withdrawn
- 2005-11-17 SI SI200530318T patent/SI1817013T1/sl unknown
- 2005-11-17 WO PCT/US2005/041736 patent/WO2006055740A1/en active Application Filing
- 2005-11-17 ES ES05824194T patent/ES2306278T3/es active Active
- 2005-11-17 MX MX2007005763A patent/MX2007005763A/es active IP Right Grant
- 2005-11-17 AU AU2005306464A patent/AU2005306464A1/en not_active Abandoned
- 2005-11-17 AT AT05824194T patent/ATE397442T1/de not_active IP Right Cessation
- 2005-11-17 DE DE602005007376T patent/DE602005007376D1/de not_active Expired - Fee Related
- 2005-11-17 EP EP08008815A patent/EP1958625A1/en not_active Withdrawn
- 2005-11-17 TW TW094140483A patent/TW200631609A/zh unknown
- 2005-11-17 KR KR1020077011236A patent/KR20070084325A/ko not_active Application Discontinuation
- 2005-11-17 RU RU2007122627/15A patent/RU2349319C1/ru not_active IP Right Cessation
-
2007
- 2007-05-09 NO NO20072388A patent/NO20072388L/no not_active Application Discontinuation
- 2007-05-10 IL IL183116A patent/IL183116A0/en unknown
- 2007-05-16 ZA ZA200703955A patent/ZA200703955B/xx unknown
-
2008
- 2008-01-10 HK HK08100342A patent/HK1106713A1/xx not_active IP Right Cessation
- 2008-07-31 HR HR20080349T patent/HRP20080349T3/xx unknown
Also Published As
Publication number | Publication date |
---|---|
DK1817013T3 (da) | 2008-10-13 |
KR20070084325A (ko) | 2007-08-24 |
WO2006055740A1 (en) | 2006-05-26 |
ZA200703955B (en) | 2008-08-27 |
NO20072388L (no) | 2007-06-14 |
PT1817013E (pt) | 2008-08-07 |
MX2007005763A (es) | 2007-07-20 |
HK1106713A1 (en) | 2008-03-20 |
PL1817013T3 (pl) | 2009-01-30 |
US20060153917A1 (en) | 2006-07-13 |
EP1817013A1 (en) | 2007-08-15 |
ES2306278T3 (es) | 2008-11-01 |
ATE397442T1 (de) | 2008-06-15 |
BRPI0518286A2 (pt) | 2008-11-11 |
JP2008520696A (ja) | 2008-06-19 |
EP1817013B1 (en) | 2008-06-04 |
DE602005007376D1 (de) | 2008-07-17 |
CA2588400A1 (en) | 2006-05-26 |
CN101083978A (zh) | 2007-12-05 |
SI1817013T1 (sl) | 2008-12-31 |
PE20061058A1 (es) | 2006-10-13 |
AU2005306464A1 (en) | 2006-05-26 |
HRP20080349T3 (en) | 2009-01-31 |
RU2349319C1 (ru) | 2009-03-20 |
IL183116A0 (en) | 2007-09-20 |
EP1958625A1 (en) | 2008-08-20 |
TW200631609A (en) | 2006-09-16 |
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Legal Events
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