AR051742A1 - Capsulas de lercanidipino - Google Patents
Capsulas de lercanidipinoInfo
- Publication number
- AR051742A1 AR051742A1 ARP050104209A ARP050104209A AR051742A1 AR 051742 A1 AR051742 A1 AR 051742A1 AR P050104209 A ARP050104209 A AR P050104209A AR P050104209 A ARP050104209 A AR P050104209A AR 051742 A1 AR051742 A1 AR 051742A1
- Authority
- AR
- Argentina
- Prior art keywords
- polyalcoholic
- fatty acid
- acid ester
- ester
- lercanidipine
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/455—Nicotinic acids, e.g. niacin; Derivatives thereof, e.g. esters, amides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4422—1,4-Dihydropyridines, e.g. nifedipine, nicardipine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4866—Organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Hydrogenated Pyridines (AREA)
Abstract
Una composicion farmacéutica de liberacion modificada comprende lercanidipino disuelto en una sustancia cérea que comprende un éster polialcoholico de ácidos grasos, encontrándose la disolucion contenida en una cápsula farmacéuticamente aceptable. Preferentemente, el éster polialcoholico de ácidos grasos es un éster del macrogol, un éster del polipropilenglicol, un glicérido de ácidos grasos o una mezcla de dos o más de los mismos. Más preferentemente, el éster polialcoholico de ácidos grasos es una mezcla de mono-, di- y triglicéridos con mono- y diésteres del macrogol. Se ha demostrado que la administracion oral a un paciente de las composiciones farmacéuticas de liberacion modificada produce una concentracion media de lercanidipino en plasma superior a los 0,5 mg/ml durante las 24 horas posteriores a la administracion.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US61591904P | 2004-10-05 | 2004-10-05 | |
US65679205P | 2005-02-25 | 2005-02-25 |
Publications (1)
Publication Number | Publication Date |
---|---|
AR051742A1 true AR051742A1 (es) | 2007-02-07 |
Family
ID=35455723
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP050104209A AR051742A1 (es) | 2004-10-05 | 2005-10-05 | Capsulas de lercanidipino |
Country Status (16)
Country | Link |
---|---|
US (1) | US20060073200A1 (es) |
EP (1) | EP1807059A1 (es) |
JP (1) | JP2008515839A (es) |
KR (1) | KR20070058632A (es) |
AR (1) | AR051742A1 (es) |
AU (1) | AU2005291354A1 (es) |
BR (1) | BRPI0516179A (es) |
CA (1) | CA2580525A1 (es) |
EA (1) | EA200700735A1 (es) |
IL (1) | IL181938A0 (es) |
MX (1) | MX2007004105A (es) |
NO (1) | NO20072332L (es) |
PE (1) | PE20060946A1 (es) |
TW (1) | TW200616681A (es) |
UY (1) | UY29150A1 (es) |
WO (1) | WO2006037650A1 (es) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AR052918A1 (es) * | 2005-02-25 | 2007-04-11 | Recordati Ireland Ltd | Clorhidrato de lercanidipina amorfo |
AR053023A1 (es) * | 2005-02-25 | 2007-04-18 | Recordati Ireland Ltd | Base libre de lercanidipina, metodos para su preparacion y composiciones farmaceuticas que las contienen |
WO2008040367A1 (en) * | 2006-08-01 | 2008-04-10 | Union Quimico-Farmaceutica S.A. | Lercanidipine hydrobromide, a process for its preparation, crystalline forms and compositions thereof |
NZ575171A (en) * | 2006-08-31 | 2012-04-27 | Aptalis Pharmatech Inc | Drug delivery systems comprising solid solutions of weakly basic drugs |
US20080175872A1 (en) * | 2006-09-28 | 2008-07-24 | Osmotica Corp. | Controlled Release Dosage Form Containing Lercanidipine and a Performance-enhancing Acid |
DE102010005124A1 (de) * | 2010-01-19 | 2012-03-01 | Stada Arzneimittel Ag | Feste pharmazeutische Zusammensetzung umfassend Lercanidipin |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8403866D0 (en) * | 1984-02-14 | 1984-03-21 | Recordati Chem Pharm | Diphenylalkylaminoalkyl esters |
HU197201B (en) * | 1985-10-01 | 1989-03-28 | Sandoz Ag | Process for producing oral pharmaceutical compositions of controlled solubility of the active components |
DE4322826A1 (de) * | 1993-07-08 | 1995-01-12 | Galenik Labor Freiburg Gmbh | Pharmazeutisches Präparat |
US5767136A (en) * | 1995-05-12 | 1998-06-16 | Recordati, S.A. Chemical And Pharmaceutical Company | 1,4-Dihydropyridines useful for prevention or reduction of atherosclerotic lesions on arterial walls |
US5696139A (en) * | 1995-05-12 | 1997-12-09 | Recordati S.A., Chemical And Pharmaceutical Company | Use of S-enantiomers of 1,4-dihydropyridine derivatives for treating heart failure |
ATE232087T1 (de) * | 1997-10-27 | 2003-02-15 | Merck Patent Gmbh | Feste lösungen und dispersionen von eines schlecht wasserlöslichen wirkstoffes |
US20030235595A1 (en) * | 1999-06-30 | 2003-12-25 | Feng-Jing Chen | Oil-containing, orally administrable pharmaceutical composition for improved delivery of a therapeutic agent |
GB2355656B (en) * | 1999-08-17 | 2004-04-07 | Galena As | Pharmaceutical compositions for oral and topical administration |
US6852737B2 (en) * | 2001-08-06 | 2005-02-08 | Recordati Ireland Limited | Crude and crystalline forms of lercanidipine hydrochloride |
US20030069285A1 (en) * | 2001-08-06 | 2003-04-10 | Recordati Ireland Limited | Novel solvate and crystalline forms of lercanidipine hydrochloride |
-
2005
- 2005-09-30 TW TW094134236A patent/TW200616681A/zh unknown
- 2005-10-03 PE PE2005001168A patent/PE20060946A1/es not_active Application Discontinuation
- 2005-10-04 UY UY29150A patent/UY29150A1/es unknown
- 2005-10-04 US US11/244,315 patent/US20060073200A1/en not_active Abandoned
- 2005-10-05 EP EP05794809A patent/EP1807059A1/en not_active Withdrawn
- 2005-10-05 KR KR1020077008950A patent/KR20070058632A/ko not_active Application Discontinuation
- 2005-10-05 AU AU2005291354A patent/AU2005291354A1/en not_active Abandoned
- 2005-10-05 JP JP2007535101A patent/JP2008515839A/ja not_active Withdrawn
- 2005-10-05 AR ARP050104209A patent/AR051742A1/es unknown
- 2005-10-05 EA EA200700735A patent/EA200700735A1/ru unknown
- 2005-10-05 WO PCT/EP2005/010813 patent/WO2006037650A1/en not_active Application Discontinuation
- 2005-10-05 BR BRPI0516179-7A patent/BRPI0516179A/pt not_active Application Discontinuation
- 2005-10-05 CA CA002580525A patent/CA2580525A1/en not_active Abandoned
- 2005-10-05 MX MX2007004105A patent/MX2007004105A/es not_active Application Discontinuation
-
2007
- 2007-03-15 IL IL181938A patent/IL181938A0/en unknown
- 2007-05-04 NO NO20072332A patent/NO20072332L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
TW200616681A (en) | 2006-06-01 |
NO20072332L (no) | 2007-05-04 |
MX2007004105A (es) | 2007-06-15 |
BRPI0516179A (pt) | 2008-08-26 |
KR20070058632A (ko) | 2007-06-08 |
IL181938A0 (en) | 2007-07-04 |
AU2005291354A1 (en) | 2006-04-13 |
US20060073200A1 (en) | 2006-04-06 |
UY29150A1 (es) | 2005-11-30 |
EA200700735A1 (ru) | 2007-10-26 |
PE20060946A1 (es) | 2006-10-02 |
JP2008515839A (ja) | 2008-05-15 |
WO2006037650A1 (en) | 2006-04-13 |
EP1807059A1 (en) | 2007-07-18 |
CA2580525A1 (en) | 2006-04-13 |
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Legal Events
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FB | Suspension of granting procedure |