AR047093A1 - Derivados de diarilmetiliden piperidina, sus preparaciones y sus usos - Google Patents
Derivados de diarilmetiliden piperidina, sus preparaciones y sus usosInfo
- Publication number
- AR047093A1 AR047093A1 ARP050100058A ARP050100058A AR047093A1 AR 047093 A1 AR047093 A1 AR 047093A1 AR P050100058 A ARP050100058 A AR P050100058A AR P050100058 A ARP050100058 A AR P050100058A AR 047093 A1 AR047093 A1 AR 047093A1
- Authority
- AR
- Argentina
- Prior art keywords
- alkyl
- cycloalkyl
- nrc
- diarilmetiliden
- piperidina
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D211/70—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Reivindicacion 1: Un compuesto de formula (1), una sal aceptable para uso farmacéutico del mismo, diastereomeros, enantiomeros, o mezclas de los mismos: en la cual R1 y R3 se seleccionan independientemente de H, alquilo C1-6, y cicloalquilo C3-6, donde dichos alquilo C1-6 y cicloalquilo C3-6 se sustituyen opcionalmente con uno o más grupos seleccionados de -R, -NO2, -OR, -Cl, -Br, -I, -F, -CF3, -C(=O)R, -C(=O)OH, -NH2, -SH, -NHR, -NR2, -SR, -SO3H, -SO2R, -S(=O)R, -CN, -OH, -C(=O)OR, - C(=O)NR2, -NRC(=O)R y -NRC(=O)-OR, donde R es, independientemente, un H o alquilo C1-6; y R2 se selecciona de alquilo C1-6, alquenilo C2-6, cicloalquilo C3-6 y cicloalquil C3-6-alquilo C1-4, donde dichos alquilo C1-6, alquenilo C2-6, cicloalquilo C3- 6, y cicloalquil C3-6-alquilo C1-4 se sustituyen opcionalmente con uno o más grupos seleccionados de -R, -NO2, -OR, -Cl, -Br, -I, -F, -CF3, -C(=O)R, -C(=O)OH, -NH2, -SH, -NHR, -NR2, -SR, -SO3H, -SO2R, -S(=O)R, -CN, -OH, -C(=O)OR, -C(=O)NR2, - NRC(=O)R y -NRC(=O)-OR, donde R es, independientemente, un H, cicloalquilo C3-6 o alquilo C1-6.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE0400026A SE0400026D0 (sv) | 2004-01-09 | 2004-01-09 | Diarylmethylidene piperidine derivatives, preparations thereof and uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR047093A1 true AR047093A1 (es) | 2006-01-04 |
Family
ID=31493011
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP050100058A AR047093A1 (es) | 2004-01-09 | 2005-01-07 | Derivados de diarilmetiliden piperidina, sus preparaciones y sus usos |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US20070219249A1 (es) |
| EP (1) | EP1706379A1 (es) |
| JP (1) | JP2007517871A (es) |
| KR (1) | KR20060123447A (es) |
| CN (1) | CN1926106A (es) |
| AR (1) | AR047093A1 (es) |
| AU (1) | AU2005204008B2 (es) |
| BR (1) | BRPI0506695A (es) |
| CA (1) | CA2552946A1 (es) |
| IL (1) | IL176509A0 (es) |
| MX (1) | MXPA06007663A (es) |
| NO (1) | NO20063618L (es) |
| SE (1) | SE0400026D0 (es) |
| TW (1) | TW200528431A (es) |
| UY (1) | UY28713A1 (es) |
| WO (1) | WO2005066127A1 (es) |
| ZA (1) | ZA200605533B (es) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE0203301D0 (sv) * | 2002-11-07 | 2002-11-07 | Astrazeneca Ab | Novel Compounds |
| RU2005136524A (ru) * | 2003-05-16 | 2006-06-27 | Астразенека Аб (Se) | Производные диарилметилиденпиперидина, способы их получения и их применение |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2898339A (en) * | 1957-07-29 | 1959-08-04 | Wm S Merrell Co | N-substituted benzhydrol, benzhydryl, and benzhydrylidene piperidine |
| US4581171A (en) * | 1983-07-27 | 1986-04-08 | Janssen Pharmaceutica, N.V. | [[Bis(aryl)methylene]-1-piperidinyl]alkyl-pyrimidinones useful for treating psychotropic disorders |
| US4816586A (en) * | 1987-07-29 | 1989-03-28 | Regents Of The University Of Minnesota | Delta opioid receptor antagonists |
| US5140029A (en) * | 1989-01-09 | 1992-08-18 | Janssen Pharmaceutica N.V. | 2-aminopyrimidinone derivatives |
| US4939137A (en) * | 1989-06-28 | 1990-07-03 | Ortho Pharmaceutical Corporation | Ring-fused thienopyrimidinedione derivatives |
| US5683998A (en) * | 1991-04-23 | 1997-11-04 | Toray Industries, Inc. | Tricyclic triazolo derivatives, processes for producing the same and the uses of the same |
| US5574159A (en) * | 1992-02-03 | 1996-11-12 | Delta Pharmaceuticals, Inc. | Opioid compounds and methods for making therefor |
| TW548271B (en) * | 1996-12-20 | 2003-08-21 | Astra Pharma Inc | Novel piperidine derivatives having an exocyclic double bond with analgesic effects |
| BR0108965A (pt) * | 2000-03-03 | 2002-11-26 | Ortho Mcneil Pharm Inc | Derivados de 3-(diarilmetileno)-8-azabiciclo[3,2,1]octano |
| US6556387B1 (en) * | 2000-03-31 | 2003-04-29 | Seagate Technology Llc | Controlling mechanical response characteristics of a disc drive actuator by adjusting a fastener engaging the actuator shaft to vary axial force on the bearing assembly |
| SE0001208D0 (sv) * | 2000-04-04 | 2000-04-04 | Astrazeneca Canada Inc | Novel compounds |
| SE0001207D0 (sv) * | 2000-04-04 | 2000-04-04 | Astrazeneca Canada Inc | Novel compounds |
| SE0101766D0 (sv) * | 2001-05-18 | 2001-05-18 | Astrazeneca Ab | Novel compounds |
| SE0101768D0 (sv) * | 2001-05-18 | 2001-05-18 | Astrazeneca Ab | Novel compounds |
| SE0101765D0 (sv) * | 2001-05-18 | 2001-05-18 | Astrazeneca Ab | Novel compounds |
-
2004
- 2004-01-09 SE SE0400026A patent/SE0400026D0/xx unknown
- 2004-12-29 TW TW093141146A patent/TW200528431A/zh unknown
-
2005
- 2005-01-05 CN CNA2005800063315A patent/CN1926106A/zh active Pending
- 2005-01-05 KR KR1020067013698A patent/KR20060123447A/ko not_active Application Discontinuation
- 2005-01-05 AU AU2005204008A patent/AU2005204008B2/en not_active Expired - Fee Related
- 2005-01-05 MX MXPA06007663A patent/MXPA06007663A/es not_active Application Discontinuation
- 2005-01-05 WO PCT/SE2005/000012 patent/WO2005066127A1/en active Application Filing
- 2005-01-05 JP JP2006549188A patent/JP2007517871A/ja not_active Abandoned
- 2005-01-05 CA CA002552946A patent/CA2552946A1/en not_active Abandoned
- 2005-01-05 US US10/596,850 patent/US20070219249A1/en not_active Abandoned
- 2005-01-05 BR BRPI0506695-6A patent/BRPI0506695A/pt not_active IP Right Cessation
- 2005-01-05 EP EP05704686A patent/EP1706379A1/en not_active Withdrawn
- 2005-01-07 AR ARP050100058A patent/AR047093A1/es unknown
- 2005-01-07 UY UY28713A patent/UY28713A1/es unknown
-
2006
- 2006-06-22 IL IL176509A patent/IL176509A0/en unknown
- 2006-07-04 ZA ZA200605533A patent/ZA200605533B/xx unknown
- 2006-08-09 NO NO20063618A patent/NO20063618L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| MXPA06007663A (es) | 2006-09-04 |
| TW200528431A (en) | 2005-09-01 |
| SE0400026D0 (sv) | 2004-01-09 |
| US20070219249A1 (en) | 2007-09-20 |
| BRPI0506695A (pt) | 2007-05-02 |
| JP2007517871A (ja) | 2007-07-05 |
| AU2005204008A1 (en) | 2005-07-21 |
| UY28713A1 (es) | 2005-08-31 |
| NO20063618L (no) | 2006-10-09 |
| ZA200605533B (en) | 2007-04-25 |
| IL176509A0 (en) | 2006-10-05 |
| EP1706379A1 (en) | 2006-10-04 |
| WO2005066127A1 (en) | 2005-07-21 |
| KR20060123447A (ko) | 2006-12-01 |
| AU2005204008B2 (en) | 2008-04-24 |
| CA2552946A1 (en) | 2005-07-21 |
| CN1926106A (zh) | 2007-03-07 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FB | Suspension of granting procedure |