AR035881A1 - Un metodo para determinar la predisposicion de un individuo a una condicion de piel, un sistema para determinar dicha predisposicion, uso de un polipeptido que comprende la secuencia de un alelo de profilagrina, o una de sus variantes o fragmentos o un polinucleotido que codifica cualquiera de estos - Google Patents

Un metodo para determinar la predisposicion de un individuo a una condicion de piel, un sistema para determinar dicha predisposicion, uso de un polipeptido que comprende la secuencia de un alelo de profilagrina, o una de sus variantes o fragmentos o un polinucleotido que codifica cualquiera de estos

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Publication number
AR035881A1
AR035881A1 ARP020101689A ARP020101689A AR035881A1 AR 035881 A1 AR035881 A1 AR 035881A1 AR P020101689 A ARP020101689 A AR P020101689A AR P020101689 A ARP020101689 A AR P020101689A AR 035881 A1 AR035881 A1 AR 035881A1
Authority
AR
Argentina
Prior art keywords
individual
predisposition
determining
profilagrin
skin condition
Prior art date
Application number
ARP020101689A
Other languages
English (en)
Inventor
Rebecca Susan Ginger
Original Assignee
Unilever Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Unilever Nv filed Critical Unilever Nv
Publication of AR035881A1 publication Critical patent/AR035881A1/es

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/16Emollients or protectives, e.g. against radiation
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/156Polymorphic or mutational markers

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pathology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Toxicology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Cosmetics (AREA)

Abstract

Un método para determinar la predisposición de un individuo a una condición de piel que comprende identificar los alelos de profilagrina presentes en el genoma de una muestra ex vivo tomada del individuo. Las condiciones de la piel incluyen la capacidad de un individuo de producir Factores Humectantes Naturales (FHN), piel seca y/o predisposición a eritema inducido por detergente. Típicamente, los alelos de profilagrina se identifican determinando la cantidad de repeticiones de filagrina codificada. En una forma de realización preferida, la identificación de alelos se realiza usando PCR. Un sistema para determinar la predisposición de un individuo a una condición de la piel que comprende medios para identificar los alelos de profilagrina presentes en el genoma de una muestra tomada del individuo. Uso de un polipéptido que comprende la secuencia de un alelo de profilagrina, o una de sus variantes o fragmentos o un polinucléotido que codifica cualquiera de éstos en la fabricación de una composición para tratar a un individuo con una condición de piel. Un polinucléotido que comprende la secuencia 5'GGA TGA AGC CTA TGA CACCAC 3' ó 5' GA CAG GAA AAG ATA ACT TCC C 3', y su uso para determinar la predisposición de un individuo a una condición de piel. Un método para identificar productos para el cuidado personal adecuados para el uso por un individuo que comprende la identificación del genotipo de profilagrina de un individuo y la selección de productos para el cuidado personal reconocidamente adecuados para usar con el genotipo de profilagrina así determinado. Estos métodos son particularmente útiles para agrupar individuos para los fines de participación en pruebas clínicas o para determinar si una preparación cosmética es adecuada para un individuo.
ARP020101689A 2001-05-09 2002-05-09 Un metodo para determinar la predisposicion de un individuo a una condicion de piel, un sistema para determinar dicha predisposicion, uso de un polipeptido que comprende la secuencia de un alelo de profilagrina, o una de sus variantes o fragmentos o un polinucleotido que codifica cualquiera de estos AR035881A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0111324.0A GB0111324D0 (en) 2001-05-09 2001-05-09 Ambient stable beverage

Publications (1)

Publication Number Publication Date
AR035881A1 true AR035881A1 (es) 2004-07-21

Family

ID=9914289

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP020101689A AR035881A1 (es) 2001-05-09 2002-05-09 Un metodo para determinar la predisposicion de un individuo a una condicion de piel, un sistema para determinar dicha predisposicion, uso de un polipeptido que comprende la secuencia de un alelo de profilagrina, o una de sus variantes o fragmentos o un polinucleotido que codifica cualquiera de estos

Country Status (11)

Country Link
US (2) US7897334B2 (es)
EP (1) EP1386007B1 (es)
JP (1) JP4099068B2 (es)
KR (1) KR20030092127A (es)
CN (1) CN100379881C (es)
AR (1) AR035881A1 (es)
CA (1) CA2444736A1 (es)
GB (1) GB0111324D0 (es)
MX (1) MXPA03010100A (es)
WO (1) WO2002090583A2 (es)
ZA (1) ZA200308137B (es)

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CA2623405C (en) 2005-09-20 2014-11-25 Immunivest Corporation Methods and composition to generate unique sequence dna probes labeling of dna probes and the use of these probes
US9134237B2 (en) * 2005-09-20 2015-09-15 Janssen Diagnotics, LLC High sensitivity multiparameter method for rare event analysis in a biological sample
GB0525492D0 (en) * 2005-12-15 2006-01-25 Univ Dundee Filaggrin
GB0600948D0 (en) * 2006-01-18 2006-02-22 Univ Dundee Prevention/Treatment Of Ichthyosis Vulgaris, Atopy And Other Disorders
EP2175778B1 (en) * 2007-06-28 2019-05-15 Erasmus University Medical Center Rotterdam Method for determination of a potential mutation
WO2010114361A1 (en) 2009-04-01 2010-10-07 River Diagnostic B.V. Method for determination of one or more mutations
EP2504357B1 (en) 2009-11-23 2017-08-02 Research Development Foundation Recombinant filaggrin polypeptides for cell importation
GB2493141A (en) * 2011-07-19 2013-01-30 Gene Onyx Ltd Method of selecting a product using a DNA sample
KR101763950B1 (ko) * 2011-08-03 2017-08-03 주식회사 엘지생활건강 주름 피부 타입 유전자 다형성 마커 및 이의 용도
WO2014108758A1 (en) 2013-01-14 2014-07-17 Itc Limited Nanoparticles dispersion for detection of skin health conditions and a diagnostic kit thereof
CN105358975B (zh) * 2013-03-15 2018-10-23 宝洁公司 用于测量皮肤健康代谢物的非侵入性方法
JP5943945B2 (ja) * 2014-01-29 2016-07-05 株式会社 資生堂 プロフィラグリンc末端ドメイン特異的抗体及びその用途
US10381105B1 (en) 2017-01-24 2019-08-13 Bao Personalized beauty system
CN111278447A (zh) * 2017-09-05 2020-06-12 阿兹特拉公司 用重组微生物治疗炎性皮肤疾病的方法和组合物
WO2022122167A1 (en) 2020-12-11 2022-06-16 Symrise Ag Medicament for preventing or treating pathologic conditions of human skin (i)

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US4302386A (en) * 1978-08-25 1981-11-24 The Ohio State University Antigenic modification of polypeptides
US4290944A (en) * 1980-07-31 1981-09-22 Northwestern University Antigenic peptide compound
US4998617A (en) 1986-09-15 1991-03-12 Laura Lupton Inc Facial cosmetic liquid make up kit
US5541308A (en) * 1986-11-24 1996-07-30 Gen-Probe Incorporated Nucleic acid probes for detection and/or quantitation of non-viral organisms
US5459039A (en) * 1989-05-12 1995-10-17 Duke University Methods for mapping genetic mutations
US4998671A (en) * 1989-10-20 1991-03-12 The Drackett Company Multiple compartment flexible package
GB9223084D0 (en) 1992-11-04 1992-12-16 Imp Cancer Res Tech Compounds to target cells
EP1262564A3 (en) 1993-01-07 2004-03-31 Sequenom, Inc. Dna sequencing by mass spectrometry
DE69310339T2 (de) 1993-02-19 1997-08-21 Howard Green Präparate, die Corneozyt Proteine enthalten
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US7625697B2 (en) * 1994-06-17 2009-12-01 The Board Of Trustees Of The Leland Stanford Junior University Methods for constructing subarrays and subarrays made thereby

Also Published As

Publication number Publication date
WO2002090583A3 (en) 2003-10-23
EP1386007B1 (en) 2016-04-27
MXPA03010100A (es) 2004-03-10
WO2002090583A2 (en) 2002-11-14
GB0111324D0 (en) 2001-07-04
CN100379881C (zh) 2008-04-09
KR20030092127A (ko) 2003-12-03
JP4099068B2 (ja) 2008-06-11
EP1386007A2 (en) 2004-02-04
ZA200308137B (en) 2004-10-20
CN1551923A (zh) 2004-12-01
JP2004531261A (ja) 2004-10-14
US20030124553A1 (en) 2003-07-03
US20110268673A1 (en) 2011-11-03
CA2444736A1 (en) 2002-11-14
US7897334B2 (en) 2011-03-01

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