AR031349A1 - Derivados de ariloxipiperidinilo para el tratamiento de la depresion - Google Patents

Derivados de ariloxipiperidinilo para el tratamiento de la depresion

Info

Publication number
AR031349A1
AR031349A1 ARP010105332A ARP010105332A AR031349A1 AR 031349 A1 AR031349 A1 AR 031349A1 AR P010105332 A ARP010105332 A AR P010105332A AR P010105332 A ARP010105332 A AR P010105332A AR 031349 A1 AR031349 A1 AR 031349A1
Authority
AR
Argentina
Prior art keywords
treatment
disease
disorder
aryloxipiperidinyl
depression
Prior art date
Application number
ARP010105332A
Other languages
English (en)
Original Assignee
Wyeth Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth Corp filed Critical Wyeth Corp
Publication of AR031349A1 publication Critical patent/AR031349A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Esta invencion provee compuestos utiles para el tratamiento de trastornos del sistema nervioso central relacionados con la serotonina, incluyendo la ansiedad, trastorno de la ansiedad generalizado, trastorno de pánico, trastorno obsesivo-compulsivo, trastornos del sueno, disfuncion sexual, adicion a las drogas y al alcohol, enfermedad de Alzheimer, enfermedad de Parkinson, obesidad y migrana, teniendo los compuestos la formula general (1) en la cual R1 y R2 cada uno puede ser H o un grupo alquilo o alcoxi, o R1 y R2 pueden ser concatenados para formar un sistema de anillos bicíclicos con el anillo de fenilo, al cual están unidos ; X es seleccionado entre hidrogeno, halogeno, ciano, alcoxi C1-6; Z es (CH2)n o carbonilo; n es 0, 1 o 2, la línea de rayas indica un enlace doble opcional; o su sal farmacéuticamente aceptable.
ARP010105332A 2000-11-16 2001-11-15 Derivados de ariloxipiperidinilo para el tratamiento de la depresion AR031349A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US25214000P 2000-11-16 2000-11-16

Publications (1)

Publication Number Publication Date
AR031349A1 true AR031349A1 (es) 2003-09-17

Family

ID=22954764

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP010105332A AR031349A1 (es) 2000-11-16 2001-11-15 Derivados de ariloxipiperidinilo para el tratamiento de la depresion

Country Status (4)

Country Link
US (1) US6610712B2 (es)
AR (1) AR031349A1 (es)
AU (1) AU2002243394A1 (es)
WO (1) WO2002048105A2 (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0203778D0 (en) * 2002-02-18 2002-04-03 Glaxo Group Ltd Compounds
US7160888B2 (en) 2003-08-22 2007-01-09 Warner Lambert Company Llc [1,8]naphthyridin-2-ones and related compounds for the treatment of schizophrenia
DE602005016836D1 (de) 2004-11-26 2009-11-05 Janssen Pharmaceutica Nv Chotischer und anxiolytischer aktivität
CN110498789B (zh) * 2018-05-17 2022-04-05 上海医药工业研究院 芳烷哌啶类衍生物及其在多靶点抗抑郁症中的应用

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2567884B1 (fr) * 1984-07-19 1987-03-06 Roussel Uclaf Nouveaux derives de l'indole, leur preparation, leur application comme medicaments et les compositions les renfermant
EP0429341A3 (en) 1989-11-20 1991-11-13 Rhone-Poulenc Sante Heterocyclic derivatives, their preparation and pharmaceuticals containing them
US5521197A (en) * 1994-12-01 1996-05-28 Eli Lilly And Company 3-<1-alkylenearyl>-4-<1,2,3,6-tetrahydropyridinyl>-and 3-<1-alkylenearyl>-4-piperidinyl-1h-indoles: new 5-HT1F agonists
US5576321A (en) 1995-01-17 1996-11-19 Eli Lilly And Company Compounds having effects on serotonin-related systems
AU736596B2 (en) * 1997-07-25 2001-08-02 H. Lundbeck A/S Indole and 2,3-dihydroindole derivatives, their preparation and use
AU3667899A (en) * 1998-04-29 1999-11-16 American Home Products Corporation Antipsychotic indolyl derivatives
CN1307576A (zh) * 1998-04-29 2001-08-08 美国家用产品公司 5－羟色胺能药物
ES2165274B1 (es) * 1999-06-04 2003-04-01 Almirall Prodesfarma Sa Nuevos derivados de indolilpiperidina como agentes antihistaminicos y antialergicos.
WO2001043740A1 (en) * 1999-12-17 2001-06-21 Bristol-Myers Squibb Company Antipsychotic heterocycle compounds
AR027134A1 (es) * 1999-12-30 2003-03-12 Lundbeck & Co As H Derivados de indol.

Also Published As

Publication number Publication date
US20020091141A1 (en) 2002-07-11
AU2002243394A1 (en) 2002-06-24
US6610712B2 (en) 2003-08-26
WO2002048105A2 (en) 2002-06-20
WO2002048105A3 (en) 2002-10-31

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