AR029189A1 - USE OF A PHOSPHODIESTERASE 4 INHIBITOR AND AN ANTI-INFLAMMATORY CORTICOESTEROID IN COMBINED FORM, SEPARATELY OR SEPARATELY SEQUENTIALLY FOR THE PREPARATION OF A MEDICINAL PRODUCT - Google Patents

USE OF A PHOSPHODIESTERASE 4 INHIBITOR AND AN ANTI-INFLAMMATORY CORTICOESTEROID IN COMBINED FORM, SEPARATELY OR SEPARATELY SEQUENTIALLY FOR THE PREPARATION OF A MEDICINAL PRODUCT

Info

Publication number
AR029189A1
AR029189A1 ARP000105742A ARP000105742A AR029189A1 AR 029189 A1 AR029189 A1 AR 029189A1 AR P000105742 A ARP000105742 A AR P000105742A AR P000105742 A ARP000105742 A AR P000105742A AR 029189 A1 AR029189 A1 AR 029189A1
Authority
AR
Argentina
Prior art keywords
separately
inhibitor
phosphodiesterase
preparation
inflammatory
Prior art date
Application number
ARP000105742A
Other languages
Spanish (es)
Original Assignee
Smithkline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Corp filed Critical Smithkline Beecham Corp
Publication of AR029189A1 publication Critical patent/AR029189A1/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Abstract

Uso de un inhibidor de la PDE4 y de un corticosteroide anti-inflamatorio en forma combinada, separadamente, o separadamente y secuencialmente que es para la preparacion de un medicamento para tratar una enfermedad pulmonar en donde la administracion secuencial está proxima en el tiempo o remota en el tiempo, particularmente se administra un inhibidor de la fosfodiesterasa 4 tal como ácido cis-4-ciano-4-(3-ciclopentiloxi-4-metoxifenil)ciclohexan-1-carboxílico en combinacion con un corticoesteroide antiinflamatorio tal como fluticasona.Use of a PDE4 inhibitor and an anti-inflammatory corticosteroid in combination, separately, or separately and sequentially that is for the preparation of a medicament to treat a lung disease where sequential administration is time or remote in In particular, a phosphodiesterase 4 inhibitor such as cis-4-cyano-4- (3-cyclopentyloxy-4-methoxyphenyl) cyclohexane-1-carboxylic acid in combination with an anti-inflammatory corticosteroid such as fluticasone is administered.

ARP000105742A 1999-11-02 2000-10-31 USE OF A PHOSPHODIESTERASE 4 INHIBITOR AND AN ANTI-INFLAMMATORY CORTICOESTEROID IN COMBINED FORM, SEPARATELY OR SEPARATELY SEQUENTIALLY FOR THE PREPARATION OF A MEDICINAL PRODUCT AR029189A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US16315899P 1999-11-02 1999-11-02

Publications (1)

Publication Number Publication Date
AR029189A1 true AR029189A1 (en) 2003-06-18

Family

ID=22588737

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP000105742A AR029189A1 (en) 1999-11-02 2000-10-31 USE OF A PHOSPHODIESTERASE 4 INHIBITOR AND AN ANTI-INFLAMMATORY CORTICOESTEROID IN COMBINED FORM, SEPARATELY OR SEPARATELY SEQUENTIALLY FOR THE PREPARATION OF A MEDICINAL PRODUCT

Country Status (29)

Country Link
EP (1) EP1225866A4 (en)
JP (1) JP2003513028A (en)
KR (1) KR20020057988A (en)
CN (1) CN1387404A (en)
AP (1) AP2002002496A0 (en)
AR (1) AR029189A1 (en)
AU (1) AU1357501A (en)
BG (1) BG106748A (en)
BR (1) BR0015270A (en)
CA (1) CA2388333A1 (en)
CO (1) CO5261512A1 (en)
CZ (1) CZ20021512A3 (en)
DZ (1) DZ3225A1 (en)
EA (1) EA200200518A1 (en)
EC (1) ECSP003747A (en)
HK (1) HK1049107A1 (en)
HU (1) HUP0203152A3 (en)
IL (1) IL149367A0 (en)
MA (1) MA26841A1 (en)
MX (1) MXPA02004350A (en)
NO (1) NO20022057L (en)
OA (1) OA12076A (en)
PE (1) PE20011005A1 (en)
PL (1) PL355261A1 (en)
SK (1) SK7592002A3 (en)
TR (1) TR200201211T2 (en)
TW (1) TWI242431B (en)
WO (1) WO2001032127A2 (en)
ZA (1) ZA200203435B (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040242597A1 (en) * 2001-09-19 2004-12-02 Thomas Klein Combination
JP2005515975A (en) * 2001-10-31 2005-06-02 メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフトング Type 4 phosphodiesterase inhibitors and uses thereof
UA82323C2 (en) * 2002-08-09 2008-04-10 Меда Фарма Гмбх & Ко. Кг Novel combination of a glucocorticoid and pde-inhibitor for the treatment of respiratory diseases, allergic diseases, asthma and chronic obstructive pulmonary diseases
TW200410923A (en) * 2002-10-17 2004-07-01 Ono Pharmaceutical Co Therapeutic agent for chronic obstructive pulmonary disease
US20060199789A1 (en) * 2003-03-31 2006-09-07 Kyowa Hakko Kogyo Co., Ltd. medical composition
US20050026883A1 (en) * 2003-07-31 2005-02-03 Robinson Cynthia B. Combination of dehydroepiandrosterone or dehydroepiandrosterone-sulfate with a PDE-4 inhibitor for treatment of asthma or chronic obstructive pulmonary disease
JPWO2006041121A1 (en) * 2004-10-13 2008-05-15 協和醗酵工業株式会社 Treatment and / or prevention agent for chronic skin diseases
BRPI0617673C1 (en) * 2005-10-19 2012-05-22 Ranbaxy Lab Ltd phosphodiesterase type iv inhibitor compositions
TWI589313B (en) 2010-01-05 2017-07-01 麥可朵斯斯若波特公司 Pharmaceutical delivery package and inhaler
WO2015063669A1 (en) 2013-10-30 2015-05-07 Wockhardt Limited Pharmaceutical compositions comprising combination of roflumilast and acebrophylline or pharmaceutically acceptable salts thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1466598A3 (en) * 1993-06-18 2007-06-27 Smithkline Beecham Corporation PDE-IV inhibitors
DE4332041C2 (en) * 1993-09-21 1997-12-11 Rentschler Arzneimittel Use of pentoxifylline in certain lung diseases
PE44995A1 (en) * 1994-01-27 1995-12-18 Schering Corp MOMETASONE FUROATE FOR THE TREATMENT OF LUNG DISEASES AND RESPIRATORY TRACT
SE9801368D0 (en) * 1998-04-20 1998-04-20 Astra Ab New use

Also Published As

Publication number Publication date
NO20022057L (en) 2002-06-27
OA12076A (en) 2006-05-04
NO20022057D0 (en) 2002-04-30
WO2001032127A2 (en) 2001-05-10
PL355261A1 (en) 2004-04-05
CZ20021512A3 (en) 2003-04-16
ZA200203435B (en) 2003-06-25
IL149367A0 (en) 2002-11-10
BG106748A (en) 2003-02-28
PE20011005A1 (en) 2001-09-28
ECSP003747A (en) 2002-05-23
SK7592002A3 (en) 2002-11-06
EP1225866A2 (en) 2002-07-31
AU1357501A (en) 2001-05-14
CO5261512A1 (en) 2003-03-31
CA2388333A1 (en) 2001-05-10
HUP0203152A2 (en) 2003-01-28
HUP0203152A3 (en) 2004-06-28
CN1387404A (en) 2002-12-25
MXPA02004350A (en) 2002-11-07
KR20020057988A (en) 2002-07-12
BR0015270A (en) 2002-06-18
JP2003513028A (en) 2003-04-08
TWI242431B (en) 2005-11-01
EP1225866A4 (en) 2004-04-21
EA200200518A1 (en) 2002-10-31
AP2002002496A0 (en) 2002-06-30
HK1049107A1 (en) 2003-05-02
WO2001032127A3 (en) 2001-12-06
DZ3225A1 (en) 2001-05-10
MA26841A1 (en) 2004-12-20
TR200201211T2 (en) 2002-08-21

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Legal Events

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