AR028986A1 - USO DE UN INHIBIDOR DE PDE4 EN LA FABRICACIoN DE UNA PREPARACIoN DE LIBERACIoN CONTROLADA; FORMULACION DE LIBERACION CONTROLADA PARA EL TRATAMIENTO DE COPD, UN PROCEDIMIENTO PARA SU PREPARACIoN Y COMPOSICIoN FARMACÉUTICA - Google Patents
USO DE UN INHIBIDOR DE PDE4 EN LA FABRICACIoN DE UNA PREPARACIoN DE LIBERACIoN CONTROLADA; FORMULACION DE LIBERACION CONTROLADA PARA EL TRATAMIENTO DE COPD, UN PROCEDIMIENTO PARA SU PREPARACIoN Y COMPOSICIoN FARMACÉUTICAInfo
- Publication number
- AR028986A1 AR028986A1 ARP000100730A ARP000100730A AR028986A1 AR 028986 A1 AR028986 A1 AR 028986A1 AR P000100730 A ARP000100730 A AR P000100730A AR P000100730 A ARP000100730 A AR P000100730A AR 028986 A1 AR028986 A1 AR 028986A1
- Authority
- AR
- Argentina
- Prior art keywords
- preparation
- controlled
- pde4 inhibitor
- copd
- procedure
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/275—Nitriles; Isonitriles
- A61K31/277—Nitriles; Isonitriles having a ring, e.g. verapamil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2009—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pulmonology (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Inorganic Chemistry (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
El uso de un inhibidor de PDE4 en la fabricacion de una preparacion de liberacion controlada para tratar eficazmente inflamacion en un mamífero con dicho inhibidor al tiempo que se evitan efectos adversos, que comprende mezclar un excipiente farmacéuticamente aceptable capaz de formar una formulacion de liberacion controlada con una cantidad terapéuticamente eficaz de un inhibidor de PDE4, cantidad que, si se administrara como un preparado de liberacion inmediata, causaría diversos efectos adversos, una formulacion de liberacion controlada o sostenida disenada para liberar un inhibidor de PDE4 para tratar una enfermedad inflamatoria tal como asma o COPD y similares, un procedimiento para su preparacion y una composicion farmacéutica de liberacion estable.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US12129199P | 1999-02-23 | 1999-02-23 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR028986A1 true AR028986A1 (es) | 2003-06-04 |
Family
ID=22395738
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP000100730A AR028986A1 (es) | 1999-02-23 | 2000-02-21 | USO DE UN INHIBIDOR DE PDE4 EN LA FABRICACIoN DE UNA PREPARACIoN DE LIBERACIoN CONTROLADA; FORMULACION DE LIBERACION CONTROLADA PARA EL TRATAMIENTO DE COPD, UN PROCEDIMIENTO PARA SU PREPARACIoN Y COMPOSICIoN FARMACÉUTICA |
Country Status (29)
| Country | Link |
|---|---|
| US (1) | US20030211152A1 (es) |
| EP (1) | EP1154758A4 (es) |
| JP (1) | JP2002537320A (es) |
| KR (1) | KR20010112279A (es) |
| CN (1) | CN1195496C (es) |
| AR (1) | AR028986A1 (es) |
| AU (1) | AU3501500A (es) |
| BG (1) | BG105905A (es) |
| BR (1) | BR0008382A (es) |
| CA (1) | CA2366747A1 (es) |
| CO (1) | CO5150233A1 (es) |
| CZ (1) | CZ20013025A3 (es) |
| EA (1) | EA200100906A1 (es) |
| HK (1) | HK1043045A1 (es) |
| HU (1) | HUP0200134A3 (es) |
| ID (1) | ID29792A (es) |
| IL (1) | IL144603A0 (es) |
| MA (1) | MA25386A1 (es) |
| MY (1) | MY121142A (es) |
| NO (1) | NO20014049L (es) |
| NZ (1) | NZ527716A (es) |
| OA (1) | OA11836A (es) |
| PE (1) | PE20001496A1 (es) |
| PL (1) | PL350287A1 (es) |
| SK (1) | SK12072001A3 (es) |
| TR (1) | TR200102448T2 (es) |
| TW (1) | TWI224013B (es) |
| WO (1) | WO2000050011A1 (es) |
| ZA (1) | ZA200106803B (es) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2389293A1 (en) * | 1999-10-29 | 2001-05-10 | Smithkline Beecham Corporation | Method for administering a phosphodiesterase 4 inhibitor |
| JP4510384B2 (ja) * | 2001-05-23 | 2010-07-21 | 田辺三菱製薬株式会社 | 骨折治癒促進用組成物 |
| JP4510383B2 (ja) * | 2001-05-23 | 2010-07-21 | 田辺三菱製薬株式会社 | 軟骨疾患修復治療用組成物 |
| WO2003024488A2 (en) * | 2001-09-19 | 2003-03-27 | Altana Pharma Ag | Combination of a pde inhibitor and a leukotriene receptor antagonist |
| MY140561A (en) | 2002-02-20 | 2009-12-31 | Nycomed Gmbh | Dosage form containing pde 4 inhibitor as active ingredient |
| TWI328009B (en) | 2003-05-21 | 2010-08-01 | Glaxo Group Ltd | Quinoline derivatives as phosphodiesterase inhibitors |
| AU2003290394A1 (en) * | 2003-09-30 | 2005-04-14 | Lupin Ltd. | Extended release formulation of beta-lactam antibiotics |
| PE20060272A1 (es) | 2004-05-24 | 2006-05-22 | Glaxo Group Ltd | (2r,3r,4s,5r,2'r,3'r,4's,5's)-2,2'-{trans-1,4-ciclohexanodiilbis-[imino(2-{[2-(1-metil-1h-imidazol-4-il)etil]amino}-9h-purin-6,9-diil)]}bis[5-(2-etil-2h-tetrazol-5-il)tetrahidro-3,4-furanodiol] como agonista a2a |
| EP2135602A1 (en) * | 2004-08-13 | 2009-12-23 | Boehringer Ingelheim International GmbH | Extended release tablet formulation containing pramipexole or a pharmaceutically acceptable salt thereof, method for manufacturing the same and use thereof |
| GB0511066D0 (en) * | 2005-05-31 | 2005-07-06 | Novartis Ag | Organic compounds |
| GB0514809D0 (en) | 2005-07-19 | 2005-08-24 | Glaxo Group Ltd | Compounds |
| CN109908139B (zh) * | 2018-12-28 | 2022-02-22 | 南京市儿童医院 | 西洛司特在制备用于治疗急性肾损伤相关病症的药物中的用途 |
| EP3911304B1 (en) * | 2019-01-15 | 2023-09-06 | UNION therapeutics A/S | Modified release tablet formulations containing phosphodiesterase inhibitors |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE636568A (es) * | 1961-01-31 | |||
| IL78017A (en) * | 1986-03-03 | 1989-06-30 | Yissum Res Dev Co | Sustained release tablets of theophylline |
| US5286494A (en) * | 1986-07-02 | 1994-02-15 | Schering Aktiengesellschaft | Medicinal agents with sustained action |
| AU677776B2 (en) * | 1992-04-02 | 1997-05-08 | Smithkline Beecham Corporation | Compounds useful for treating allergic and inflammatory diseases |
| GB9222253D0 (en) * | 1992-10-23 | 1992-12-09 | Celltech Ltd | Chemical compounds |
| US5672622A (en) * | 1994-04-21 | 1997-09-30 | Berlex Laboratories, Inc. | Treatment of multiple sclerosis |
| US5998428A (en) * | 1995-05-31 | 1999-12-07 | Smithkline Beecham Corporation | Compounds and methods for treating PDE IV-related diseases |
| US6210710B1 (en) * | 1997-04-28 | 2001-04-03 | Hercules Incorporated | Sustained release polymer blend for pharmaceutical applications |
| US5840329A (en) * | 1997-05-15 | 1998-11-24 | Bioadvances Llc | Pulsatile drug delivery system |
| AR035987A1 (es) * | 1999-03-01 | 2004-08-04 | Smithkline Beecham Corp | Uso de un compuesto inhibidor de la pde 4 para la manufactura de un medicamento y el medicamento para tratar asma inducida por ejercicio |
-
2000
- 2000-02-21 MY MYPI20000615A patent/MY121142A/en unknown
- 2000-02-21 AR ARP000100730A patent/AR028986A1/es not_active Application Discontinuation
- 2000-02-22 BR BR0008382-8A patent/BR0008382A/pt not_active IP Right Cessation
- 2000-02-22 PL PL00350287A patent/PL350287A1/xx not_active Application Discontinuation
- 2000-02-22 ID IDW00200101812A patent/ID29792A/id unknown
- 2000-02-22 CZ CZ20013025A patent/CZ20013025A3/cs unknown
- 2000-02-22 AU AU35015/00A patent/AU3501500A/en not_active Abandoned
- 2000-02-22 IL IL14460300A patent/IL144603A0/xx unknown
- 2000-02-22 OA OA1200100217A patent/OA11836A/en unknown
- 2000-02-22 EP EP00913600A patent/EP1154758A4/en not_active Withdrawn
- 2000-02-22 KR KR1020017010666A patent/KR20010112279A/ko not_active Application Discontinuation
- 2000-02-22 WO PCT/US2000/004713 patent/WO2000050011A1/en not_active Application Discontinuation
- 2000-02-22 CA CA002366747A patent/CA2366747A1/en not_active Abandoned
- 2000-02-22 SK SK1207-2001A patent/SK12072001A3/sk unknown
- 2000-02-22 NZ NZ527716A patent/NZ527716A/en unknown
- 2000-02-22 PE PE2000000135A patent/PE20001496A1/es not_active Application Discontinuation
- 2000-02-22 HU HU0200134A patent/HUP0200134A3/hu unknown
- 2000-02-22 TR TR2001/02448T patent/TR200102448T2/xx unknown
- 2000-02-22 CN CNB008042098A patent/CN1195496C/zh not_active Expired - Fee Related
- 2000-02-22 EA EA200100906A patent/EA200100906A1/ru unknown
- 2000-02-22 JP JP2000600623A patent/JP2002537320A/ja not_active Withdrawn
- 2000-02-23 CO CO00012706A patent/CO5150233A1/es unknown
- 2000-03-15 TW TW089103003A patent/TWI224013B/zh not_active IP Right Cessation
-
2001
- 2001-08-17 ZA ZA200106803A patent/ZA200106803B/en unknown
- 2001-08-20 NO NO20014049A patent/NO20014049L/no unknown
- 2001-08-23 MA MA26303A patent/MA25386A1/fr unknown
- 2001-09-14 BG BG105905A patent/BG105905A/bg unknown
-
2002
- 2002-04-12 HK HK02102791.5A patent/HK1043045A1/zh unknown
-
2003
- 2003-06-12 US US10/460,613 patent/US20030211152A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| KR20010112279A (ko) | 2001-12-20 |
| EP1154758A1 (en) | 2001-11-21 |
| CO5150233A1 (es) | 2002-04-29 |
| PL350287A1 (en) | 2002-12-02 |
| ZA200106803B (en) | 2002-08-19 |
| CN1195496C (zh) | 2005-04-06 |
| NO20014049D0 (no) | 2001-08-20 |
| JP2002537320A (ja) | 2002-11-05 |
| TWI224013B (en) | 2004-11-21 |
| CZ20013025A3 (cs) | 2002-07-17 |
| US20030211152A1 (en) | 2003-11-13 |
| ID29792A (id) | 2001-10-11 |
| CN1347314A (zh) | 2002-05-01 |
| IL144603A0 (en) | 2002-05-23 |
| SK12072001A3 (sk) | 2002-01-07 |
| HUP0200134A2 (hu) | 2002-05-29 |
| TR200102448T2 (tr) | 2003-03-21 |
| EA200100906A1 (ru) | 2002-02-28 |
| AU3501500A (en) | 2000-09-14 |
| NZ527716A (en) | 2005-03-24 |
| HK1043045A1 (zh) | 2002-09-06 |
| PE20001496A1 (es) | 2001-02-08 |
| NO20014049L (no) | 2001-10-22 |
| MY121142A (en) | 2005-12-30 |
| EP1154758A4 (en) | 2007-09-05 |
| BR0008382A (pt) | 2002-02-05 |
| HUP0200134A3 (en) | 2003-03-28 |
| OA11836A (en) | 2005-08-22 |
| CA2366747A1 (en) | 2000-08-31 |
| BG105905A (bg) | 2002-04-30 |
| MA25386A1 (fr) | 2002-04-01 |
| WO2000050011A1 (en) | 2000-08-31 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA | Abandonment or withdrawal |