AR026708A1 - DERIVATIVES OF 5-HYDROXY-INDAZOL FOR THE TREATMENT OF GLAUCOMA - Google Patents

DERIVATIVES OF 5-HYDROXY-INDAZOL FOR THE TREATMENT OF GLAUCOMA

Info

Publication number
AR026708A1
AR026708A1 ARP000106395A ARP000106395A AR026708A1 AR 026708 A1 AR026708 A1 AR 026708A1 AR P000106395 A ARP000106395 A AR P000106395A AR P000106395 A ARP000106395 A AR P000106395A AR 026708 A1 AR026708 A1 AR 026708A1
Authority
AR
Argentina
Prior art keywords
indazol
glaucoma
treatment
hydroxy
derivatives
Prior art date
Application number
ARP000106395A
Other languages
Spanish (es)
Original Assignee
Alcon Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alcon Inc filed Critical Alcon Inc
Publication of AR026708A1 publication Critical patent/AR026708A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A61K31/416—1,2-Diazoles condensed with carbocyclic ring systems, e.g. indazole
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/54—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
    • C07D231/56—Benzopyrazoles; Hydrogenated benzopyrazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Ophthalmology & Optometry (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Se describen 3-(2-aminoetil)-1H-indazol-5-oles utiles para el tratamiento de la presion intraocular elevada y glaucoma.3- (2-Aminoethyl) -1H-indazol-5-oles useful for the treatment of elevated intraocular pressure and glaucoma are described.

ARP000106395A 2000-03-17 2000-12-01 DERIVATIVES OF 5-HYDROXY-INDAZOL FOR THE TREATMENT OF GLAUCOMA AR026708A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US19028300P 2000-03-17 2000-03-17

Publications (1)

Publication Number Publication Date
AR026708A1 true AR026708A1 (en) 2003-02-26

Family

ID=22700701

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP000106395A AR026708A1 (en) 2000-03-17 2000-12-01 DERIVATIVES OF 5-HYDROXY-INDAZOL FOR THE TREATMENT OF GLAUCOMA

Country Status (12)

Country Link
EP (1) EP1268439A1 (en)
JP (1) JP2003535821A (en)
KR (1) KR20030095183A (en)
CN (1) CN1450995A (en)
AR (1) AR026708A1 (en)
AU (2) AU2001219180B2 (en)
BR (1) BR0017163A (en)
CA (1) CA2401959A1 (en)
MX (1) MXPA02008825A (en)
PL (1) PL365422A1 (en)
WO (1) WO2001070701A1 (en)
ZA (1) ZA200206853B (en)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6960579B1 (en) 1998-05-19 2005-11-01 Alcon Manufacturing, Ltd. Serotonergic 5HT7 receptor compounds for treating ocular and CNS disorders
EP1392292B1 (en) 2001-06-01 2006-03-01 Alcon, Inc. Pyranoindazoles and their use for the treatment of glaucoma
TW593302B (en) 2001-12-20 2004-06-21 Alcon Inc Novel benzodifuranimidazoline and benzofuranimidazoline derivatives and their use for the treatment of glaucoma
WO2004043354A2 (en) 2002-11-08 2004-05-27 Merck & Co., Inc. Ophthalmic compositions for treating ocular hypertension
CN100384827C (en) * 2002-11-08 2008-04-30 默克公司 Ophthalmic compositions for treating ocular hypertension
US7196082B2 (en) * 2002-11-08 2007-03-27 Merck & Co. Inc. Ophthalmic compositions for treating ocular hypertension
MXPA05006277A (en) 2002-12-13 2005-09-08 Alcon Inc Novel benzopyran analogs and their use for the treatment of glaucoma.
JP2004262812A (en) * 2003-02-28 2004-09-24 Rohto Pharmaceut Co Ltd Hypotonia bulbi medicine
JP2007504236A (en) * 2003-09-04 2007-03-01 メルク　エンド　カムパニー　インコーポレーテッド Ophthalmic composition for treating ocular hypertension
US7129257B1 (en) 2003-12-15 2006-10-31 Alcon, Inc. Pyrazolo[3,4- e]benzoxazoles for the treatment of glaucoma
WO2005058911A2 (en) 2003-12-15 2005-06-30 Alcon, Inc. Substituted [1,4]oxazino[2,3-g]indazoles for the treatment of glaucoma
US7338972B1 (en) 2003-12-15 2008-03-04 Alcon, Inc. Substituted 1-alkylamino-1H-indazoles for the treatment of glaucoma
KR20070094747A (en) 2004-11-29 2007-09-21 워너-램버트 캄파니 엘엘씨 Therapeutic pyrazolo[3,4-b]pyridines and indazoles
US7425572B2 (en) 2004-12-08 2008-09-16 Alcon, Inc. Use of dioxindoindazoles and dioxoloindazoles for treating glaucoma
KR100972921B1 (en) * 2009-12-02 2010-07-28 제이케이이앤씨 주식회사 An apparatus for cleaning and deodorizing of rotation diaphragmed type vortex

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2680366B1 (en) * 1991-08-13 1995-01-20 Adir NOVEL ARYLETHYLAMINE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM.
AU3978899A (en) * 1998-05-19 1999-12-06 Alcon Laboratories, Inc. Serotonergic 5HT, receptor compounds for treating ocular and CNS disorders
GB9819020D0 (en) * 1998-09-01 1998-10-28 Cerebrus Ltd Chemical compounds III
WO2000016761A2 (en) * 1998-09-18 2000-03-30 Alcon Laboratories, Inc. Serotonergic 5ht2 agonists for treating glaucoma

Also Published As

Publication number Publication date
CN1450995A (en) 2003-10-22
BR0017163A (en) 2003-01-14
AU1918001A (en) 2001-10-03
PL365422A1 (en) 2005-01-10
AU2001219180B2 (en) 2005-04-07
EP1268439A1 (en) 2003-01-02
CA2401959A1 (en) 2001-09-27
ZA200206853B (en) 2004-11-02
KR20030095183A (en) 2003-12-18
MXPA02008825A (en) 2004-10-15
WO2001070701A1 (en) 2001-09-27
JP2003535821A (en) 2003-12-02

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