AR026105A1 - HETEROARILO, HETEROCICLICO AND ILO COMPUTERS THAT - Google Patents

HETEROARILO, HETEROCICLICO AND ILO COMPUTERS THAT

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Publication number
AR026105A1
AR026105A1 ARP000100287A ARP000100287A AR026105A1 AR 026105 A1 AR026105 A1 AR 026105A1 AR P000100287 A ARP000100287 A AR P000100287A AR P000100287 A ARP000100287 A AR P000100287A AR 026105 A1 AR026105 A1 AR 026105A1
Authority
AR
Argentina
Prior art keywords
compounds
disease
heterociclico
heteroarilo
ilo
Prior art date
Application number
ARP000100287A
Other languages
Spanish (es)
Original Assignee
Wyeth Corp
Elan Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth Corp, Elan Pharm Inc filed Critical Wyeth Corp
Publication of AR026105A1 publication Critical patent/AR026105A1/en

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Se describen compuestos que se adhieren a VLA-4. Algunos de estos compuestos inhiben también la adhesion de leucocitos, y un particular, la adhesion deleucocitos intermedia por VLA-4 de los compuestos utiles para el tratamiento de enfermedades inflam atorias en un paciente mamífero, por ejemplo en un serhumano, tales como asma, enfermedad de Alzheimer, ateroes-clerosis, demencia causada por SIDA, diabetes, enfermedad inflamatoria del intestino, artritisreumatoide, transplante de tejidos, metástas is de tumores e isquemia de miocardio. Los compuestos pueden suministrarse también para el tratamiento deenfermedades cerebrales inflamatorias tales como esclerosis multiple.Compounds that adhere to VLA-4 are described. Some of these compounds also inhibit the adhesion of leukocytes, and in particular, the adhesion deleucocytes intermediate by VLA-4 of the compounds useful for the treatment of inflammatory diseases in a mammalian patient, for example in a human being, such as asthma, disease Alzheimer's disease, atherosclerosis, dementia caused by AIDS, diabetes, inflammatory bowel disease, rheumatoid arthritis, tissue transplantation, tumor metastases and myocardial ischemia. The compounds can also be supplied for the treatment of inflammatory brain diseases such as multiple sclerosis.

ARP000100287A 1996-04-09 2000-01-24 HETEROARILO, HETEROCICLICO AND ILO COMPUTERS THAT AR026105A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US1199996A 1996-04-09 1996-04-09
US11692399P 1999-01-22 1999-01-22
US16099999P 1999-10-21 1999-10-21

Publications (1)

Publication Number Publication Date
AR026105A1 true AR026105A1 (en) 2003-01-29

Family

ID=37515090

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP000100287A AR026105A1 (en) 1996-04-09 2000-01-24 HETEROARILO, HETEROCICLICO AND ILO COMPUTERS THAT

Country Status (1)

Country Link
AR (1) AR026105A1 (en)

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