AR018861A1 - Composicion farmaceutica para el tratamiento de la impotencia masculina o la disfuncion erectil que comprende un mono- o dinitrato organico y uso dedicho mono- o dinitrato organico para fabricarla - Google Patents
Composicion farmaceutica para el tratamiento de la impotencia masculina o la disfuncion erectil que comprende un mono- o dinitrato organico y uso dedicho mono- o dinitrato organico para fabricarlaInfo
- Publication number
- AR018861A1 AR018861A1 ARP990102349A ARP990102349A AR018861A1 AR 018861 A1 AR018861 A1 AR 018861A1 AR P990102349 A ARP990102349 A AR P990102349A AR P990102349 A ARP990102349 A AR P990102349A AR 018861 A1 AR018861 A1 AR 018861A1
- Authority
- AR
- Argentina
- Prior art keywords
- dinitrate
- mono
- nitrate
- organic
- erectile dysfunction
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/04—Nitro compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Reproductive Health (AREA)
- Gynecology & Obstetrics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Urology & Nephrology (AREA)
- Endocrinology (AREA)
- Organic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Plant Substances (AREA)
- Orthopedics, Nursing, And Contraception (AREA)
Abstract
Una composicion farmacéutica para el tratamiento de la impotencia masculina o la disfuncion eréctil que comprende un mono- o dinitrato orgánicoen un portador topico o parenteral farmacéuticamente aceptable, siendo dicho mono- o dinitrato seleccionadodel grupo integrado por 1,5-pentano dinitrato,1,4-butano dinitrato, 1,6-hexano dinitrato, 1,7-heptano dinitrato, isoamil nitrato, isobutil nitrato, neopentil nitrato, ciclopentil nitrato, 2-pentanonitrato, 1-penteno-5-nitrato, 2-metil-2-buteno-4-nitrato, en donde dicho mono- o dinitrato orgánico está presente en una cantidad efectiva para tratar laimpotencia o la disfuncion erécril. Dicho portador topico puede ser seleccionado del grupo integrado por pomadas, geles, cremas, lociones, líquidos,sprays, parches y cintas. La composicion que contiene suficiente mono- o dinitrato orgánico a los efectos de proveer entre 0,1 y 40 mg de nitrato pordosis aplicada en el pene. Dicha dosis comprende entre 50 y 800 mg. de composicion topica. El uso de un mono- o dinitrato orgánico para la fabricacionde la composicion farmacéutica que comprende en un portador topico o parenteral farmacéuticamente aceptable, dicho mono- o dinitrato, el cual estápresente en una cantidad efectiva para tratar la impotencia o la disfuncion eréctil, en donde dicha composicion farmacéutica es util para tratar laimpotencia masculina o la disfuncion eréctil en humanos por medio de la administracion local en el pene.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/081,108 US6056966A (en) | 1998-05-18 | 1998-05-18 | Method and compositions for treating impotence |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR018861A1 true AR018861A1 (es) | 2001-12-12 |
Family
ID=22162141
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP990102349A AR018861A1 (es) | 1998-05-18 | 1999-05-18 | Composicion farmaceutica para el tratamiento de la impotencia masculina o la disfuncion erectil que comprende un mono- o dinitrato organico y uso dedicho mono- o dinitrato organico para fabricarla |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US6056966A (es) |
| EP (1) | EP1079823A1 (es) |
| JP (1) | JP2003511343A (es) |
| KR (1) | KR20010071283A (es) |
| CN (1) | CN1307472A (es) |
| AR (1) | AR018861A1 (es) |
| AU (1) | AU758035B2 (es) |
| BR (1) | BR9911060A (es) |
| CA (1) | CA2332328A1 (es) |
| CO (1) | CO5050298A1 (es) |
| HU (1) | HUP0101668A2 (es) |
| IL (1) | IL139751A0 (es) |
| NO (1) | NO20005793L (es) |
| PL (1) | PL344335A1 (es) |
| SK (1) | SK17452000A3 (es) |
| WO (1) | WO1999059575A1 (es) |
| ZA (1) | ZA200006733B (es) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6852323B2 (en) | 2000-07-21 | 2005-02-08 | The Regents Of The University Of California | Methods and compositions for preventing and treating male erectile dysfunction and female sexual arousal disorder |
| US7223406B2 (en) * | 2000-07-21 | 2007-05-29 | The Regents Of The University Of California | Methods and compositions for preventing and treating male erectile dysfunction and female sexual arousal disorder |
| CN1308438C (zh) * | 2002-01-11 | 2007-04-04 | 大卫·R·怀特洛克 | 含有氨氧化细菌的化合物以及使用的方法 |
| US20030219696A1 (en) * | 2002-05-23 | 2003-11-27 | Moreland Gerald W. | Method and apparatus for preventing backflow in dental saliva evacuators |
| EP1667646A4 (en) * | 2003-09-26 | 2007-07-04 | David R Whitlock | METHOD FOR USE OF AMMONIA-OXIDATING BACTERIA |
| US7507842B2 (en) | 2005-08-12 | 2009-03-24 | Radiorx, Inc. | Cyclic nitro compounds, pharmaceutical compositions thereof and uses thereof |
| US20070135380A1 (en) * | 2005-08-12 | 2007-06-14 | Radiorx, Inc. | O-nitro compounds, pharmaceutical compositions thereof and uses thereof |
| US20070175484A1 (en) * | 2006-01-30 | 2007-08-02 | Staab Robert J | Condoms for beneficial agents delivery |
| US8212735B2 (en) * | 2009-06-05 | 2012-07-03 | Nokia Corporation | Near field communication |
| WO2011057386A1 (en) * | 2009-11-13 | 2011-05-19 | Oral Delivery Technology Ltd. | Composition and prophylactic device for enhancing sexual performance or pleasure |
| US9023890B2 (en) | 2009-12-02 | 2015-05-05 | The Charlotte-Mecklenburg Hospital Authority | Nitrate esters and their use for the treatment of muscle and muscle related diseases |
| US8471041B2 (en) * | 2010-02-09 | 2013-06-25 | Alliant Techsystems Inc. | Methods of synthesizing and isolating N-(bromoacetyl)-3,3-dinitroazetidine and a composition including the same |
| US9452117B2 (en) | 2011-06-01 | 2016-09-27 | The Charlotte-Mecklenburg Hospital Authority | Nitrate esters and their use for the treatment of muscle and muscle related diseases |
| US8664247B2 (en) | 2011-08-26 | 2014-03-04 | Radiorx, Inc. | Acyclic organonitro compounds for use in treating cancer |
| AU2012319071B2 (en) | 2011-10-07 | 2017-08-03 | Epicentrx, Inc. | Organonitro thioether compounds and medical uses thereof |
| WO2013052803A2 (en) | 2011-10-07 | 2013-04-11 | Radiorx, Inc. | Methods and compositions comprising a nitrite-reductase promoter for treatment of medical disorders and preservation of blood products |
| CN104352436A (zh) * | 2014-10-09 | 2015-02-18 | 南京泽恒医药技术开发有限公司 | 一种***原位成形凝胶喷雾剂及其制备方法 |
| US10342778B1 (en) | 2015-10-20 | 2019-07-09 | Epicentrx, Inc. | Treatment of brain metastases using organonitro compound combination therapy |
| US9987270B1 (en) | 2015-10-29 | 2018-06-05 | Epicentrix, Inc. | Treatment of gliomas using organonitro compound combination therapy |
| CN109069420A (zh) | 2016-01-11 | 2018-12-21 | 埃皮辛特瑞柯斯公司 | 2-溴-1-(3，3-二硝基氮杂环丁烷-1-基)乙酮静脉施用的组合物和方法 |
| CN110352190A (zh) | 2016-10-14 | 2019-10-18 | 埃皮辛特瑞柯斯公司 | 用于医疗用途的磺氧基烷基有机硝基和相关化合物和药物组合物 |
| CA3069004A1 (en) | 2017-07-07 | 2019-01-10 | Epicentrx, Inc. | Compositions for parenteral administration of therapeutic agents |
| US11510901B2 (en) | 2018-01-08 | 2022-11-29 | Epicentrx, Inc. | Methods and compositions utilizing RRx-001 combination therapy for radioprotection |
| RU2757309C1 (ru) * | 2020-11-02 | 2021-10-13 | Ассим Абдель Гани Ахмед Сонбол | Композиция для коррекции сексуальной дисфункции у мужчин |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4112115A (en) * | 1976-11-08 | 1978-09-05 | Coghlan Charles C | Therapy of leg muscle cramps |
| US4913469A (en) * | 1988-08-08 | 1990-04-03 | Cameron Iron Works Usa, Inc. | Wellhead slip and seal assembly |
| NL8802276A (nl) * | 1988-09-15 | 1990-04-02 | Cedona Pharm Bv | Geneesmiddel met relaxerende werking, dat als aktieve stof een nitraatester bevat. |
| JPH02200633A (ja) * | 1989-01-27 | 1990-08-08 | Akamatsu Shoji Kk | 血管拡張剤 |
| US5059603A (en) * | 1989-06-12 | 1991-10-22 | Centuries Laboratories, Inc. | Method and composition for treating impotence |
| US5646181A (en) * | 1992-07-02 | 1997-07-08 | Research Foundation Of State University Of New York | Method and compositions for treating impotence |
| US5278192A (en) * | 1992-07-02 | 1994-01-11 | The Research Foundation Of State University Of New York | Method of vasodilator therapy for treating a patient with a condition |
| KR960700702A (ko) * | 1993-03-15 | 1996-02-24 | 헤르베르트 서키·울리히 볼프 | 병리적으로 상승된 안내 압력을 치료하는데 치환된 알킬니트레이트를 사용하는 방법(use of substituted alkyl nitrates for the treatment of pathologically increased intraocular pressure) |
| CA2215307A1 (en) * | 1995-03-14 | 1996-09-19 | Vivus, Incorporated | Pharmaceutical compositions and kits for preventing erectile dysfunction |
| EP0998274B1 (en) * | 1997-06-23 | 2006-01-18 | Cellegy Pharmaceuticals, Inc | Microdose therapy of vascular conditions by no donors |
-
1998
- 1998-05-18 US US09/081,108 patent/US6056966A/en not_active Expired - Fee Related
-
1999
- 1999-05-18 AR ARP990102349A patent/AR018861A1/es not_active Application Discontinuation
- 1999-05-18 AU AU40006/99A patent/AU758035B2/en not_active Ceased
- 1999-05-18 KR KR1020007012921A patent/KR20010071283A/ko not_active Application Discontinuation
- 1999-05-18 CA CA002332328A patent/CA2332328A1/en not_active Abandoned
- 1999-05-18 CN CN99807875A patent/CN1307472A/zh active Pending
- 1999-05-18 IL IL13975199A patent/IL139751A0/xx unknown
- 1999-05-18 CO CO99030405A patent/CO5050298A1/es unknown
- 1999-05-18 PL PL99344335A patent/PL344335A1/xx unknown
- 1999-05-18 SK SK1745-2000A patent/SK17452000A3/sk unknown
- 1999-05-18 BR BR9911060-1A patent/BR9911060A/pt not_active IP Right Cessation
- 1999-05-18 EP EP99923179A patent/EP1079823A1/en not_active Withdrawn
- 1999-05-18 HU HU0101668A patent/HUP0101668A2/hu unknown
- 1999-05-18 JP JP2000549240A patent/JP2003511343A/ja active Pending
- 1999-05-18 WO PCT/US1999/010933 patent/WO1999059575A1/en not_active Application Discontinuation
-
2000
- 2000-11-16 NO NO20005793A patent/NO20005793L/no not_active Application Discontinuation
- 2000-11-17 ZA ZA200006733A patent/ZA200006733B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US6056966A (en) | 2000-05-02 |
| NO20005793L (no) | 2001-01-17 |
| PL344335A1 (en) | 2001-11-05 |
| EP1079823A1 (en) | 2001-03-07 |
| CN1307472A (zh) | 2001-08-08 |
| CA2332328A1 (en) | 1999-11-25 |
| IL139751A0 (en) | 2002-02-10 |
| NO20005793D0 (no) | 2000-11-16 |
| ZA200006733B (en) | 2001-09-18 |
| KR20010071283A (ko) | 2001-07-28 |
| WO1999059575A1 (en) | 1999-11-25 |
| JP2003511343A (ja) | 2003-03-25 |
| BR9911060A (pt) | 2001-02-06 |
| CO5050298A1 (es) | 2001-06-27 |
| HUP0101668A2 (hu) | 2001-10-28 |
| AU758035B2 (en) | 2003-03-13 |
| AU4000699A (en) | 1999-12-06 |
| SK17452000A3 (sk) | 2001-08-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA | Abandonment or withdrawal |