AR014847A1 - 4-AMINO- (ETILAMINO) -OOPINDIN OXINDOLS OF THE DOPAMINE SELF-RECEPTOR AND A PHARMACEUTICAL COMPOSITION THAT UNDERSTANDS - Google Patents
4-AMINO- (ETILAMINO) -OOPINDIN OXINDOLS OF THE DOPAMINE SELF-RECEPTOR AND A PHARMACEUTICAL COMPOSITION THAT UNDERSTANDSInfo
- Publication number
- AR014847A1 AR014847A1 ARP990101678A ARP990101678A AR014847A1 AR 014847 A1 AR014847 A1 AR 014847A1 AR P990101678 A ARP990101678 A AR P990101678A AR P990101678 A ARP990101678 A AR P990101678A AR 014847 A1 AR014847 A1 AR 014847A1
- Authority
- AR
- Argentina
- Prior art keywords
- amino
- pharmaceutical composition
- oxindols
- oopindin
- etilamino
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/32—Oxygen atoms
- C07D209/34—Oxygen atoms in position 2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Psychiatry (AREA)
- Psychology (AREA)
- Addiction (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
Abstract
4-Amino-(etilamino)-oxindoles agonistas del autoreceptor de dopamina, que comprende un compuesto de formula (I), donde R1 y R2 son cada uno,independientemente, hidrogeno, alquilo C1-10, o (CH2)mR4, donde R4 es fenilo o naftilo que puede sustituirse por uno o dos sustituyentes seleccionados delgrupo formado por alquilo C1-6, halogeno, alcoxido C1-6 y trifluormetilo y m es de 1 a 5; y R3 es hidrogeno o alquilo C1-6; o sales farmacéuticamente aceptablede los mismos y una composicion farmacéuticaque los comprende.4-Amino- (ethylamino) -oxyindole agonists of the dopamine autoreceptor, comprising a compound of formula (I), where R1 and R2 are each, independently, hydrogen, C1-10 alkyl, or (CH2) mR4, where R4 it is phenyl or naphthyl which can be substituted by one or two substituents selected from the group consisting of C1-6 alkyl, halogen, C1-6 alkoxy and trifluoromethyl and m is from 1 to 5; and R3 is hydrogen or C1-6 alkyl; or pharmaceutically acceptable salts thereof and a pharmaceutical composition comprising them.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US5883498A | 1998-04-13 | 1998-04-13 |
Publications (1)
Publication Number | Publication Date |
---|---|
AR014847A1 true AR014847A1 (en) | 2001-03-28 |
Family
ID=22019205
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP990101678A AR014847A1 (en) | 1998-04-13 | 1999-04-12 | 4-AMINO- (ETILAMINO) -OOPINDIN OXINDOLS OF THE DOPAMINE SELF-RECEPTOR AND A PHARMACEUTICAL COMPOSITION THAT UNDERSTANDS |
Country Status (8)
Country | Link |
---|---|
EP (1) | EP1073636A1 (en) |
JP (1) | JP2002511450A (en) |
CN (1) | CN1297439A (en) |
AR (1) | AR014847A1 (en) |
AU (1) | AU3555099A (en) |
CA (1) | CA2327477A1 (en) |
WO (1) | WO1999052870A1 (en) |
ZA (1) | ZA992670B (en) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AR032641A1 (en) * | 2001-01-29 | 2003-11-19 | Otsuka Pharma Co Ltd | RECEIVER SUBTIPE AGONIST 5-HT 1A. |
US7053092B2 (en) | 2001-01-29 | 2006-05-30 | Otsuka Pharmaceutical Co., Ltd. | 5-HT1a receptor subtype agonist |
US8703772B2 (en) | 2001-09-25 | 2014-04-22 | Otsuka Pharmaceutical Co., Ltd. | Low hygroscopic aripiprazole drug substance and processes for the preparation thereof |
AR033485A1 (en) | 2001-09-25 | 2003-12-26 | Otsuka Pharma Co Ltd | MEDICINAL SUBSTANCE OF ARIPIPRAZOL OF LOW HYGROSCOPICITY AND PROCESS FOR THE PREPARATION OF THE SAME |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4452808A (en) * | 1982-12-07 | 1984-06-05 | Smithkline Beckman Corporation | 4-Aminoalkyl-2(3H)-indolones |
GB8712073D0 (en) * | 1987-05-21 | 1987-06-24 | Smith Kline French Lab | Medicament |
AU4312593A (en) * | 1992-05-18 | 1993-12-13 | Smithkline Beecham Plc | Use of indolone derivatives for the treatment of memory disorders, sexual dysfunction and Parkinson's disease |
AU4088897A (en) * | 1996-08-27 | 1998-03-19 | American Home Products Corporation | 4-aminoethoxy indolone derivatives |
-
1999
- 1999-04-12 CA CA002327477A patent/CA2327477A1/en not_active Abandoned
- 1999-04-12 JP JP2000543433A patent/JP2002511450A/en active Pending
- 1999-04-12 CN CN99805030A patent/CN1297439A/en active Pending
- 1999-04-12 WO PCT/US1999/007967 patent/WO1999052870A1/en not_active Application Discontinuation
- 1999-04-12 ZA ZA9902670A patent/ZA992670B/en unknown
- 1999-04-12 EP EP99917423A patent/EP1073636A1/en not_active Withdrawn
- 1999-04-12 AU AU35550/99A patent/AU3555099A/en not_active Abandoned
- 1999-04-12 AR ARP990101678A patent/AR014847A1/en unknown
Also Published As
Publication number | Publication date |
---|---|
ZA992670B (en) | 2000-10-12 |
EP1073636A1 (en) | 2001-02-07 |
CN1297439A (en) | 2001-05-30 |
AU3555099A (en) | 1999-11-01 |
WO1999052870A1 (en) | 1999-10-21 |
JP2002511450A (en) | 2002-04-16 |
CA2327477A1 (en) | 1999-10-21 |
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