AR012702A1 - COMBINATION OF (-) - (1S, 4R) -4- [2-AMINO-6- (CICLOPROPILAMINO) -9H-PURIN-9-IL] - 2-CYCLOPENTENO-1-METHANOL AND A REVERSE NON-NUCLEOSIDUNE FORMULATION TRANSCRIPTASE INHIBITOR PHARMACEUTICAL WHICH INCLUDES THE COMBINATION, ITS MEDICAL USE IN THERAPY TO TREAT HIV INFECTION, AND A PACKAGING FOR THE PATIENT - Google Patents
COMBINATION OF (-) - (1S, 4R) -4- [2-AMINO-6- (CICLOPROPILAMINO) -9H-PURIN-9-IL] - 2-CYCLOPENTENO-1-METHANOL AND A REVERSE NON-NUCLEOSIDUNE FORMULATION TRANSCRIPTASE INHIBITOR PHARMACEUTICAL WHICH INCLUDES THE COMBINATION, ITS MEDICAL USE IN THERAPY TO TREAT HIV INFECTION, AND A PACKAGING FOR THE PATIENTInfo
- Publication number
- AR012702A1 AR012702A1 ARP980102250A ARP980102250A AR012702A1 AR 012702 A1 AR012702 A1 AR 012702A1 AR P980102250 A ARP980102250 A AR P980102250A AR P980102250 A ARP980102250 A AR P980102250A AR 012702 A1 AR012702 A1 AR 012702A1
- Authority
- AR
- Argentina
- Prior art keywords
- combination
- purin
- methanol
- amino
- patient
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/52—Purines, e.g. adenine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Virology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- AIDS & HIV (AREA)
- Tropical Medicine & Parasitology (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
Se describen combinaciones terapéuticas de (-)(1S,4R)-4-[2-amino-6- (ciclopropilamino)-9H-purin-9-il]-2-ciclopenteno-1-metanol (1592U89) einhibidores de transcriptasa reversa, no nucleosidos que tienen actividad anti- VIH. La presente invencion también está relacionada con composicionesfarmacéuticas que contienen las combinaciones, su uso en el tratamiento de infecciones VIH y un empaque para el paciente que contiene dichas combinacionesTherapeutic combinations of (-) (1S, 4R) -4- [2-amino-6- (cyclopropylamino) -9H-purin-9-yl] -2-cyclopentene-1-methanol (1592U89) and reverse transcriptase inhibitors are described , non-nucleosides that have anti-HIV activity. The present invention is also related to pharmaceutical compositions containing the combinations, their use in the treatment of HIV infections and a patient package containing such combinations.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB9709945.1A GB9709945D0 (en) | 1997-05-17 | 1997-05-17 | A novel salt |
GBGB9719883.2A GB9719883D0 (en) | 1997-09-19 | 1997-09-19 | Antiviral combinations |
Publications (1)
Publication Number | Publication Date |
---|---|
AR012702A1 true AR012702A1 (en) | 2000-11-08 |
Family
ID=26311543
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP980102250A AR012702A1 (en) | 1997-05-17 | 1998-05-14 | COMBINATION OF (-) - (1S, 4R) -4- [2-AMINO-6- (CICLOPROPILAMINO) -9H-PURIN-9-IL] - 2-CYCLOPENTENO-1-METHANOL AND A REVERSE NON-NUCLEOSIDUNE FORMULATION TRANSCRIPTASE INHIBITOR PHARMACEUTICAL WHICH INCLUDES THE COMBINATION, ITS MEDICAL USE IN THERAPY TO TREAT HIV INFECTION, AND A PACKAGING FOR THE PATIENT |
Country Status (12)
Country | Link |
---|---|
EP (1) | EP0979082A1 (en) |
JP (1) | JP2001525839A (en) |
AR (1) | AR012702A1 (en) |
AU (1) | AU7912398A (en) |
BR (1) | BR9809127A (en) |
CA (1) | CA2289655A1 (en) |
CO (1) | CO4950569A1 (en) |
HR (1) | HRP980264A2 (en) |
MA (1) | MA26496A1 (en) |
NO (1) | NO995620L (en) |
PE (1) | PE74799A1 (en) |
WO (1) | WO1998052570A1 (en) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
HRP990030A2 (en) * | 1998-02-17 | 1999-10-31 | Michael B. Maurin | Oral liquid formulations of benzoxazinones hiv reverse transcriptase inhibitors |
CO5070643A1 (en) * | 1998-05-27 | 2001-08-28 | Merck & Co Inc | FORMULATION IN COMPRESSED TABLETS |
EP1332757B1 (en) * | 1998-05-27 | 2012-06-13 | Merck Sharp & Dohme Corp. | Efavirenz compressed tablet formulation |
US20010014352A1 (en) | 1998-05-27 | 2001-08-16 | Udit Batra | Compressed tablet formulation |
WO2013111147A1 (en) * | 2011-12-19 | 2013-08-01 | Hetero Research Foundation | Extended release compositions of nevirapine |
WO2014133085A1 (en) * | 2013-02-27 | 2014-09-04 | 国立大学法人京都大学 | Pharmaceutical composition for prevention and/or treatment of cancer |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9417249D0 (en) * | 1994-08-26 | 1994-10-19 | Wellcome Found | A novel salt |
MY115461A (en) * | 1995-03-30 | 2003-06-30 | Wellcome Found | Synergistic combinations of zidovudine, 1592u89 and 3tc |
-
1998
- 1998-05-14 JP JP54991198A patent/JP2001525839A/en active Pending
- 1998-05-14 WO PCT/EP1998/002836 patent/WO1998052570A1/en not_active Application Discontinuation
- 1998-05-14 PE PE1998000375A patent/PE74799A1/en not_active Application Discontinuation
- 1998-05-14 AR ARP980102250A patent/AR012702A1/en unknown
- 1998-05-14 AU AU79123/98A patent/AU7912398A/en not_active Abandoned
- 1998-05-14 BR BR9809127-1A patent/BR9809127A/en not_active Application Discontinuation
- 1998-05-14 CA CA002289655A patent/CA2289655A1/en not_active Abandoned
- 1998-05-14 EP EP98929309A patent/EP0979082A1/en not_active Withdrawn
- 1998-05-15 CO CO98027484A patent/CO4950569A1/en unknown
- 1998-05-15 MA MA25076A patent/MA26496A1/en unknown
- 1998-05-15 HR HR9719883.2A patent/HRP980264A2/en not_active Application Discontinuation
-
1999
- 1999-11-16 NO NO995620A patent/NO995620L/en not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
HRP980264A2 (en) | 1999-02-28 |
WO1998052570A1 (en) | 1998-11-26 |
JP2001525839A (en) | 2001-12-11 |
CA2289655A1 (en) | 1998-11-26 |
PE74799A1 (en) | 1999-08-13 |
MA26496A1 (en) | 2004-12-20 |
NO995620L (en) | 2000-01-14 |
CO4950569A1 (en) | 2000-09-01 |
BR9809127A (en) | 2000-08-01 |
AU7912398A (en) | 1998-12-11 |
EP0979082A1 (en) | 2000-02-16 |
NO995620D0 (en) | 1999-11-16 |
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