AR012294A1 - Derivados de sulfonamida, un procedimiento para su preparacion, composiciones farmaceuticas que los contienen, uso de dichos derivados para lapreparacion de un medicamento. - Google Patents

Derivados de sulfonamida, un procedimiento para su preparacion, composiciones farmaceuticas que los contienen, uso de dichos derivados para lapreparacion de un medicamento.

Info

Publication number
AR012294A1
AR012294A1 ARP980101342A ARP980101342A AR012294A1 AR 012294 A1 AR012294 A1 AR 012294A1 AR P980101342 A ARP980101342 A AR P980101342A AR P980101342 A ARP980101342 A AR P980101342A AR 012294 A1 AR012294 A1 AR 012294A1
Authority
AR
Argentina
Prior art keywords
preparation
derivatives
procedure
pharmaceutical compositions
sulfonamide
Prior art date
Application number
ARP980101342A
Other languages
English (en)
Original Assignee
Smithkline Beecham Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Plc filed Critical Smithkline Beecham Plc
Publication of AR012294A1 publication Critical patent/AR012294A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/15—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings
    • C07C311/16—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom
    • C07C311/19—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom to an acyclic carbon atom of a hydrocarbon radical substituted by carboxyl groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/22—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound oxygen atoms
    • C07C311/29—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound oxygen atoms having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring

Abstract

Derivados de sulfonamida que comprenden compuestos de formula I: en la que R es hidroxi, hidrogeno, alquenilo, alquinilo o arilo, y R1 es arilo o heteroarilo, son utiles en el tratamiento y la profilaxis de estados mediados por CD23 o TNF. Además sedescribe un procedimiento para su preparacion, composicionesfarmacéuticas que los contienen, uso de dichos derivados para la preparacion de un medicamento.
ARP980101342A 1997-03-26 1998-03-24 Derivados de sulfonamida, un procedimiento para su preparacion, composiciones farmaceuticas que los contienen, uso de dichos derivados para lapreparacion de un medicamento. AR012294A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9706255.8A GB9706255D0 (en) 1997-03-26 1997-03-26 Novel compounds

Publications (1)

Publication Number Publication Date
AR012294A1 true AR012294A1 (es) 2000-10-18

Family

ID=10809882

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP980101342A AR012294A1 (es) 1997-03-26 1998-03-24 Derivados de sulfonamida, un procedimiento para su preparacion, composiciones farmaceuticas que los contienen, uso de dichos derivados para lapreparacion de un medicamento.

Country Status (18)

Country Link
US (1) US6242467B1 (es)
EP (1) EP0973732A2 (es)
JP (1) JP2001518922A (es)
KR (1) KR20010005627A (es)
CN (1) CN1251091A (es)
AR (1) AR012294A1 (es)
AU (1) AU7210598A (es)
BR (1) BR9808366A (es)
CA (1) CA2285439A1 (es)
CO (1) CO4950563A1 (es)
GB (1) GB9706255D0 (es)
HU (1) HUP0003021A3 (es)
IL (1) IL131751A0 (es)
NO (1) NO994671D0 (es)
PL (1) PL336039A1 (es)
TR (1) TR199902357T2 (es)
WO (1) WO1998042659A2 (es)
ZA (1) ZA982517B (es)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5904697A (en) * 1995-02-24 1999-05-18 Heartport, Inc. Devices and methods for performing a vascular anastomosis
IL134273A0 (en) * 1997-07-31 2001-04-30 Procter & Gamble Acyclic metalloprotease inhibitors
US6403632B1 (en) * 2000-03-01 2002-06-11 Bristol Myers Squibb Pharma Co Lactam metalloprotease inhibitors
US6340691B1 (en) 1999-01-27 2002-01-22 American Cyanamid Company Alkynyl containing hydroxamic acid compounds as matrix metalloproteinase and tace inhibitors
US6277885B1 (en) 1999-01-27 2001-08-21 American Cyanamid Company Acetylenic aryl sulfonamide and phosphinic acid amide hydroxamic acid TACE inhibitors
US6753337B2 (en) 1999-01-27 2004-06-22 Wyeth Holdings Corporation Alkynyl containing hydroxamic acid compounds as matrix metalloproteinase/tace inhibitors
US6946473B2 (en) 1999-01-27 2005-09-20 Wyeth Holdings Corporation Preparation and use of acetylenic ortho-sulfonamido and phosphinic acid amido bicyclic heteroaryl hydroxamic acids as TACE inhibitors
US6313123B1 (en) 1999-01-27 2001-11-06 American Cyanamid Company Acetylenic sulfonamide thiol tace inhibitors
US6326516B1 (en) 1999-01-27 2001-12-04 American Cyanamid Company Acetylenic β-sulfonamido and phosphinic acid amide hydroxamic acid TACE inhibitors
US6225311B1 (en) 1999-01-27 2001-05-01 American Cyanamid Company Acetylenic α-amino acid-based sulfonamide hydroxamic acid tace inhibitors
US6762178B2 (en) 1999-01-27 2004-07-13 Wyeth Holdings Corporation Acetylenic aryl sulfonamide and phosphinic acid amide hydroxamic acid TACE inhibitors
US6200996B1 (en) 1999-01-27 2001-03-13 American Cyanamid Company Heteroaryl acetylenic sulfonamide and phosphinic acid amide hydroxamic acid tace inhibitors
EP1147085B1 (en) 1999-01-27 2005-11-16 Wyeth Holdings Corporation Alkynyl containing hydroxamic acid derivatives, their preparation and their use as matrix metalloproteinase (mmp) inhibitors / tnf-alpha converting enzyme (tace) inhibitors
US6566381B1 (en) 1999-03-03 2003-05-20 The Procter & Gamble Company Hetero-substituted metalloprotease inhibitors
EP1165501A1 (en) 1999-03-03 2002-01-02 The Procter & Gamble Company Alkenyl- and alkynyl-containing metalloprotease inhibitors
GB9922825D0 (en) * 1999-09-25 1999-11-24 Smithkline Beecham Biolog Medical use
US6808902B1 (en) 1999-11-12 2004-10-26 Amgen Inc. Process for correction of a disulfide misfold in IL-1Ra Fc fusion molecules
WO2001062715A1 (en) * 2000-02-24 2001-08-30 Smithkline Beecham P.L.C. Novel cd23 inhibitors
MXPA02011553A (es) * 2000-05-25 2003-04-25 Smithkline Beecham Plc N-hidroxiformamidas sustituidas por biciclico heterobiciclilmetansulfonilamino.
SG173211A1 (en) 2001-06-26 2011-08-29 Amgen Inc Antibodies to opgl
CA2464727A1 (en) 2001-11-01 2003-05-08 Wyeth Holdings Corporation Allenic aryl sulfonamide hydroxamic acids as matrix metalloproteinase and tace inhibitors
GB0128376D0 (en) * 2001-11-27 2002-01-16 Smithkline Beecham Plc Novel compounds
DE60226489D1 (de) * 2001-12-27 2008-06-19 Lg Electronics Inc Waschmaschine
US7504425B2 (en) 2002-05-29 2009-03-17 Merck & Co., Inc. Compounds useful in the treatment of anthrax and inhibiting lethal factor
AU2003304456A1 (en) 2002-12-23 2005-03-16 Wyeth Holdings Corporation Acetylenic aryl sulfonate hydroxamic acid tace and matrix metalloproteinase inhibitors
WO2005118529A2 (en) 2004-05-11 2005-12-15 Merck & Co., Inc. Process for making n-sulfonated-amino acid derivatives
JP2011528013A (ja) * 2008-07-14 2011-11-10 ノバルティス アーゲー ヒドロキサム酸系の選択的ｍｍｐ−１２およびｍｍｐ−１３阻害剤
USD810196S1 (en) * 2015-04-14 2018-02-13 Marcia D. Fackler Sunglass book cover

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5455258A (en) 1993-01-06 1995-10-03 Ciba-Geigy Corporation Arylsulfonamido-substituted hydroxamic acids
GB2303850B (en) 1994-06-22 1998-06-10 British Biotech Pharm Metalloproteinase inhibitors
GB9414157D0 (en) * 1994-07-13 1994-08-31 Smithkline Beecham Plc Medical use
CN1198096A (zh) * 1995-08-08 1998-11-04 菲布洛根有限公司 用于治疗与胶原蛋白过量产生有关的疾病的c－蛋白酶抑制剂
ES2185750T3 (es) 1995-08-08 2003-05-01 Ono Pharmaceutical Co Derivados de acido hidroxamico utiles para la inhibicion gelatinasa.
EA001561B1 (ru) 1996-05-17 2001-04-23 Варнер-Ламберт Компани Бифенилсульфонамидные ингибиторы матричных металлопротеиназ
EP0931045A1 (en) 1996-09-04 1999-07-28 Warner-Lambert Company Matrix metalloproteinase inhibitors and their therapeutic uses

Also Published As

Publication number Publication date
HUP0003021A2 (hu) 2002-01-28
PL336039A1 (en) 2000-06-05
IL131751A0 (en) 2001-03-19
KR20010005627A (ko) 2001-01-15
WO1998042659A2 (en) 1998-10-01
GB9706255D0 (en) 1997-05-14
AU7210598A (en) 1998-10-20
JP2001518922A (ja) 2001-10-16
CA2285439A1 (en) 1998-10-01
NO994671L (no) 1999-09-24
BR9808366A (pt) 2000-05-23
US6242467B1 (en) 2001-06-05
TR199902357T2 (xx) 2000-05-22
NO994671D0 (no) 1999-09-24
ZA982517B (en) 1999-09-27
HUP0003021A3 (en) 2002-02-28
EP0973732A2 (en) 2000-01-26
CO4950563A1 (es) 2000-09-01
WO1998042659A3 (en) 1999-02-25
CN1251091A (zh) 2000-04-19

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