AR008243A1 - Un derivado de 1-[6-(piridin-3-iloxi)-pirid(az)in-3-ilcarbamoil]indolina, un procedimiento para su preparacion, composicion farmaceutica y su uso para lafabricacion de un medicamento - Google Patents
Un derivado de 1-[6-(piridin-3-iloxi)-pirid(az)in-3-ilcarbamoil]indolina, un procedimiento para su preparacion, composicion farmaceutica y su uso para lafabricacion de un medicamentoInfo
- Publication number
- AR008243A1 AR008243A1 ARP970102673A ARP970102673A AR008243A1 AR 008243 A1 AR008243 A1 AR 008243A1 AR P970102673 A ARP970102673 A AR P970102673A AR P970102673 A ARP970102673 A AR P970102673A AR 008243 A1 AR008243 A1 AR 008243A1
- Authority
- AR
- Argentina
- Prior art keywords
- preparation
- indoline
- derivative
- ilcarbamoil
- pirid
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
Un derivado de 1-[6-(piridin-3-iloxi)-pirid(az)in-3-ilcarbamoil]indolina de fórmula (I) o una de sus sales; donde x es CH o N; R1 es hidrógeno o alquiloC1-C6; los grupos R2 y R3 son independientemente halógeno, alquilo C1-6 o trifluorometilo conactividad farmacológica, a procedimientos para supreparación, a composiciones que los contienen y a su uso para la preparación de un medicamento en el tratamiento de trastornos del sistema nervioso central,tales como ansiedad.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9612883.0A GB9612883D0 (en) | 1996-06-20 | 1996-06-20 | Novel compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR008243A1 true AR008243A1 (es) | 1999-12-29 |
Family
ID=10795575
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP970102673A AR008243A1 (es) | 1996-06-20 | 1997-06-18 | Un derivado de 1-[6-(piridin-3-iloxi)-pirid(az)in-3-ilcarbamoil]indolina, un procedimiento para su preparacion, composicion farmaceutica y su uso para lafabricacion de un medicamento |
Country Status (33)
| Country | Link |
|---|---|
| US (1) | US6369060B1 (es) |
| EP (1) | EP0912554B1 (es) |
| JP (1) | JP2000512306A (es) |
| KR (1) | KR20000022045A (es) |
| CN (1) | CN1229408A (es) |
| AP (2) | AP9801410A0 (es) |
| AR (1) | AR008243A1 (es) |
| AT (1) | ATE228514T1 (es) |
| AU (1) | AU718597B2 (es) |
| BG (1) | BG103089A (es) |
| BR (1) | BR9709911A (es) |
| CA (1) | CA2258240A1 (es) |
| CO (1) | CO4890847A1 (es) |
| CZ (1) | CZ420598A3 (es) |
| DE (1) | DE69717449T2 (es) |
| DZ (1) | DZ2250A1 (es) |
| EA (1) | EA001780B1 (es) |
| ES (1) | ES2187783T3 (es) |
| GB (1) | GB9612883D0 (es) |
| HU (1) | HUP9903439A3 (es) |
| ID (1) | ID19433A (es) |
| IL (1) | IL127417A0 (es) |
| MA (1) | MA24214A1 (es) |
| NO (1) | NO985972D0 (es) |
| NZ (1) | NZ333229A (es) |
| OA (1) | OA10944A (es) |
| PE (1) | PE86698A1 (es) |
| PL (1) | PL330796A1 (es) |
| SK (1) | SK282706B6 (es) |
| TR (1) | TR199802661T2 (es) |
| TW (1) | TW382015B (es) |
| WO (1) | WO1997048699A1 (es) |
| ZA (1) | ZA975415B (es) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU3030899A (en) * | 1998-02-25 | 1999-09-15 | Smithkline Beecham Plc | Process(es) for the preparation of 6-trifluoromethyl-indoline derivatives |
| GB0019950D0 (en) * | 2000-08-12 | 2000-09-27 | Smithkline Beecham Plc | Compounds |
| MXPA04005151A (es) | 2001-11-28 | 2004-08-11 | Upjohn Co | Compuestos terapeuticos. |
| BR0308223A (pt) * | 2002-03-04 | 2005-06-28 | Pharmacia & Upjohn Co Llc | Derivados de piridiniloxi como ligantes de receptor 5-ht |
| KR101062376B1 (ko) * | 2008-04-10 | 2011-09-06 | 한국화학연구원 | 신규 인돌 카르복실산 비스피리딜 카르복사마이드 유도체,이의 제조방법 및 이를 유효성분으로 함유하는 조성물 |
| AU2010204995A1 (en) | 2009-01-16 | 2011-08-18 | Massachusetts Institute Of Technology | Diagnosis and treatment of autism spectrum disorders |
| US20130267544A1 (en) | 2010-12-17 | 2013-10-10 | Peter Adamson | Use of LP-PLA2 Inhibitors in the Treatment and Prevention of Eye Diseases |
| WO2014046544A1 (en) | 2012-09-21 | 2014-03-27 | Aapa B.V. | Substituted 3-heteroaryloxy-3-(hetero)aryl-propylamines as serotonin transporter and serotonin ht2c receptor modulators |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1989001333A1 (en) * | 1987-08-07 | 1989-02-23 | The Australian National University | IMIDAZO[1,2-b]PYRIDAZINES |
| CA2142721A1 (en) * | 1992-08-20 | 1994-03-03 | Ian T. Forbes | Condensed indole derivatives as 5ht and 5ht antagonists |
| GB9313913D0 (en) | 1993-07-06 | 1993-08-18 | Smithkline Beecham Plc | Novel compounds |
| EA000304B1 (ru) * | 1995-02-02 | 1999-04-29 | Смитклайн Бичам Плс | Производные индола как антагонисты рецептора 5-ht |
| GB9607219D0 (en) * | 1996-04-04 | 1996-06-12 | Smithkline Beecham Plc | Novel compounds |
| GB9615767D0 (en) * | 1996-07-26 | 1996-09-04 | Smithkline Beecham Plc | Novel treatment |
-
1996
- 1996-06-20 GB GBGB9612883.0A patent/GB9612883D0/en active Pending
-
1997
- 1997-06-16 KR KR1019980710443A patent/KR20000022045A/ko not_active Application Discontinuation
- 1997-06-16 AT AT97928224T patent/ATE228514T1/de not_active IP Right Cessation
- 1997-06-16 CN CN97197311A patent/CN1229408A/zh active Pending
- 1997-06-16 EA EA199900043A patent/EA001780B1/ru not_active IP Right Cessation
- 1997-06-16 EP EP97928224A patent/EP0912554B1/en not_active Expired - Lifetime
- 1997-06-16 TR TR1998/02661T patent/TR199802661T2/xx unknown
- 1997-06-16 JP JP10502259A patent/JP2000512306A/ja active Pending
- 1997-06-16 HU HU9903439A patent/HUP9903439A3/hu unknown
- 1997-06-16 CZ CZ984205A patent/CZ420598A3/cs unknown
- 1997-06-16 WO PCT/EP1997/003156 patent/WO1997048699A1/en not_active Application Discontinuation
- 1997-06-16 AP APAP/P/1998/001410A patent/AP9801410A0/en unknown
- 1997-06-16 DE DE69717449T patent/DE69717449T2/de not_active Expired - Fee Related
- 1997-06-16 BR BR9709911A patent/BR9709911A/pt unknown
- 1997-06-16 PL PL97330796A patent/PL330796A1/xx unknown
- 1997-06-16 ES ES97928224T patent/ES2187783T3/es not_active Expired - Lifetime
- 1997-06-16 IL IL12741797A patent/IL127417A0/xx unknown
- 1997-06-16 CA CA002258240A patent/CA2258240A1/en not_active Abandoned
- 1997-06-16 NZ NZ333229A patent/NZ333229A/xx unknown
- 1997-06-16 AU AU32602/97A patent/AU718597B2/en not_active Ceased
- 1997-06-16 US US09/202,780 patent/US6369060B1/en not_active Expired - Fee Related
- 1997-06-16 SK SK1752-98A patent/SK282706B6/sk unknown
- 1997-06-18 MA MA24666A patent/MA24214A1/fr unknown
- 1997-06-18 AR ARP970102673A patent/AR008243A1/es unknown
- 1997-06-18 DZ DZ970100A patent/DZ2250A1/fr active
- 1997-06-18 AP APAP/P/1997/001037A patent/AP745A/en active
- 1997-06-18 PE PE1997000510A patent/PE86698A1/es not_active Application Discontinuation
- 1997-06-19 ZA ZA975415A patent/ZA975415B/xx unknown
- 1997-06-19 TW TW086108551A patent/TW382015B/zh not_active IP Right Cessation
- 1997-06-20 CO CO97034431A patent/CO4890847A1/es unknown
- 1997-06-20 ID IDP972126A patent/ID19433A/id unknown
-
1998
- 1998-12-18 OA OA9800245A patent/OA10944A/en unknown
- 1998-12-18 NO NO985972A patent/NO985972D0/no unknown
-
1999
- 1999-01-15 BG BG103089A patent/BG103089A/xx unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| MX9307940A (es) | Nuevos derivados de la imidazopiridina, proceso para su preparacion y formulaciones farmaceuticas que los incluyen | |
| AR004516A1 (es) | Derivados de pirimidina, su uso, procedimientos para prepararlos y medicamentos que los contienen | |
| MX9305379A (es) | Nuevos derivados de aminoacidos, procedimiento para su preparacion y preparado farmaceutico que los contiene. | |
| MX9301348A (es) | Nuevos compuestos que tienen actividad farmacologica, proceso para su preparacion y composicion farmaceutica que los comprende. | |
| AR035774A1 (es) | Derivados benzimidazol y piridilimidazol, un procedimiento para su preparacion, composiciones farmaceuticas y paquetes que los comprenden, el uso de dichos compuestos solos o en combinacion para la manufactura de medicamentos como ligandos para gabaa, y metodo de tratamiento | |
| AR022303A1 (es) | Derivados de piperidina, tetrahidropiridina y piperazina, su preparacion y utilizacion | |
| UY24560A1 (es) | Derivados arilos de la pirimidina útiles como antagonistas 5ht2b selectivos | |
| ES2171884T3 (es) | Compuestos de quinazolina. | |
| AR036114A1 (es) | Tetrahidroimidazol[1,2-a]pirazinas y tetrahidrotriazol[4,3-a]pirazinas como inhibidores de la dipeptidil peptidasa utiles para el tratamiento o la prevencion de la diabetes | |
| GT199800046A (es) | Compuestos de pirazina. | |
| AR066460A2 (es) | Compuestos derivados de fenil-piperazina, fenil-piperidina y fenil-tetrahidropiridina como inhibidores de la reabsorcion de la serotonina, una composicion farmaceutica y utilizacion de los mismos para la preparacion de medicamentos | |
| AR002705A1 (es) | Un nuevo compuesto de indolina, un proceso para su preparacion y composiciones farmaceuticas que lo contienen. | |
| DE3483629D1 (de) | 2-pyrimidinyl-l-piperazin-derivate, verfahren zu ihrer herstellung und diese enthaltende arzneimittel. | |
| AR015432A1 (es) | Compuestos derivados de oxindol sustituidos, composiciones farmaceuticas, uso de dichos compuestos para la preparacion de medicamentos | |
| AR009357A1 (es) | Compuesto de amidas de acido fosfinico y sus usos para preparar una composicion farmaceutica y en un metodo para prevenir o tratar unaenfermedad asociada a la actividad de metaloproteasa | |
| AR006119A1 (es) | Compuestos de quinoxalinadionas uso de los mismos para la fabricacion de un medicamento, compuestos de quinoxalinas para producirlos y procedimiento parala preparacion de los mismos | |
| PA8432901A1 (es) | Compuestos de piridilpirrol | |
| MX9300786A (es) | Compuestos hipolipidaemicos. | |
| FR2724384B1 (fr) | Nouveaux derives de la 3,4-dihydro beta-carboline agonistes de la melatonine, leur procede de preparation et leur utilisation a titre de medicament | |
| ES2150353A1 (es) | Tienilazolilalcoxietanaminas, su preparacion y su aplicacion como medicamentos. | |
| ES2084339T3 (es) | Tetrahidropiridinas e hidroxipiperidinas sustituidas utiles como agentes para el sistema nervioso central. | |
| AR008243A1 (es) | Un derivado de 1-[6-(piridin-3-iloxi)-pirid(az)in-3-ilcarbamoil]indolina, un procedimiento para su preparacion, composicion farmaceutica y su uso para lafabricacion de un medicamento | |
| PA8458301A1 (es) | 2-aminopiridinas con sustituyentes alcoxi ramificados | |
| ZA806399B (en) | New 2-hydroxyalkyl-3,4,5-trihydroxypiperidine compounds, their production and their medicinal use | |
| AR035818A1 (es) | Fenil-heterociclil-eteres con actividad como inhibidores selectivos de recaptacion de serotonina, composiciones farmaceuticas y su uso en la fabricacion de medicamentos |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FB | Suspension of granting procedure |