AR006638A1 - Un polipeptido de sintasa isoprenoide quimerico, un metodo para su produccion, un adn que codifica dicho polipeptido, el adn que esta contenidodentro de una celula y un vector que contiene el adn - Google Patents
Un polipeptido de sintasa isoprenoide quimerico, un metodo para su produccion, un adn que codifica dicho polipeptido, el adn que esta contenidodentro de una celula y un vector que contiene el adnInfo
- Publication number
- AR006638A1 AR006638A1 ARP970101486A ARP970101486A AR006638A1 AR 006638 A1 AR006638 A1 AR 006638A1 AR P970101486 A ARP970101486 A AR P970101486A AR P970101486 A ARP970101486 A AR P970101486A AR 006638 A1 AR006638 A1 AR 006638A1
- Authority
- AR
- Argentina
- Prior art keywords
- isoprenoid
- polypeptide
- dna
- isoprenoid synthase
- synthase
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
- C12N15/8243—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/88—Lyases (4.)
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Medicinal Chemistry (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Nutrition Science (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
- Enzymes And Modification Thereof (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Un polipéptido de sintasa isoprenoide quimérica que está seleccionado del grupo que consiste de: (a) un polipéptido de sintasa isoprenoide quimérica queincluye un dominio de una primer sintasa isoprenoide unido a un dominio de una segunda sintasaisoprenoide diferente, con lo cual el polipéptido de sintasaisoprenoide quimérica es capaz de catalizar la producción de un producto de reacción isoprenoide que no es producido en la ausencia del dominio de lasegunda sintasa isoprenoidediferente , en donde:(i) la primer sintasa isoprenoide cataliza la producción de un producto de reacción isoprenoide de laprimer sintasa isoprenoide, pero no cataliza la producción de un producto de reacción isoprenoide de la segundasintasa isopr enoide diferente; (ii) lasegunda sintasa isoprenoide cataliza la producción de un producto de reacción isoprenoide de la segunda sintasa isoprenoide diferente, pero no cataliza laproducción de un producto de reacción isoprenoide dela sintasa isopr enoide; (iii) el dominio de la primer sintasa isoprenoide ocupa una primer posición enel polipéptido de sintasa isoprenoide quimérica, la primer posición en el polipéptido de sintasa isoprenoide quimérica corresponde a unaposición en laprim er sintasa isoprenoide ocupada por el dominio de la primer sintasa isoprenoide; y (iv) el dominio de la segunda sintasa isoprenoide diferenteocupa una segunda posición en el polipéptido de sintasa isoprenoide quimérica,la segunda posición en dicho polipéptido de sintasa isoprenoide quiméricacorresponde a una posición en la segunda sintasa isoprenoide diferente ocupada por el dominio de la segunda sintasa isoprenoide diferente; y (b) unpolipéptido de sintasaisoprenoide quimérica que incluye un dominio homólogo asimétricamente posicionado, con lo cual el polipéptido de sintasa isoprenoide
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/631,341 US5824774A (en) | 1996-04-12 | 1996-04-12 | Chimeric isoprenoid synthases and uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR006638A1 true AR006638A1 (es) | 1999-09-08 |
Family
ID=24530791
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP970101486A AR006638A1 (es) | 1996-04-12 | 1997-04-14 | Un polipeptido de sintasa isoprenoide quimerico, un metodo para su produccion, un adn que codifica dicho polipeptido, el adn que esta contenidodentro de una celula y un vector que contiene el adn |
Country Status (26)
| Country | Link |
|---|---|
| US (2) | US5824774A (es) |
| EP (2) | EP0904095B1 (es) |
| JP (4) | JP2000508899A (es) |
| KR (1) | KR20000005385A (es) |
| AP (1) | AP808A (es) |
| AR (1) | AR006638A1 (es) |
| AT (1) | ATE223225T1 (es) |
| AU (1) | AU2726497A (es) |
| BR (1) | BR9708650A (es) |
| CA (1) | CA2250712C (es) |
| CZ (1) | CZ294613B6 (es) |
| DE (2) | DE69715192T2 (es) |
| EA (1) | EA001622B1 (es) |
| ES (1) | ES2132046T3 (es) |
| GR (1) | GR990300025T1 (es) |
| HK (1) | HK1017275A1 (es) |
| ID (1) | ID19769A (es) |
| IL (2) | IL126486A0 (es) |
| IN (1) | IN186316B (es) |
| OA (1) | OA10895A (es) |
| PL (1) | PL329404A1 (es) |
| PT (1) | PT904095E (es) |
| TR (1) | TR199802043T2 (es) |
| TW (1) | TW509724B (es) |
| WO (1) | WO1997038703A1 (es) |
| ZA (1) | ZA973108B (es) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8106260B2 (en) * | 1996-04-12 | 2012-01-31 | The Board Of Trustees Of The University Of Kentucky | Chimeric isoprenoid synthases and uses thereof |
| US5824774A (en) * | 1996-04-12 | 1998-10-20 | Board Of Trustees Of The University Of Kentucky | Chimeric isoprenoid synthases and uses thereof |
| US7186891B1 (en) * | 1996-04-12 | 2007-03-06 | University Of Kentucky, Research Foundation | Plant cells and plants expressing chimeric isoprenoid synthases |
| US5945726A (en) * | 1996-12-16 | 1999-08-31 | Micron Technology, Inc. | Lateral bipolar transistor |
| AR022383A1 (es) | 1998-09-18 | 2002-09-04 | Univ Kentucky Res Found | Sintasas |
| US6358712B1 (en) | 1999-01-05 | 2002-03-19 | Trustee Of Boston University | Ordered gene assembly |
| AU774306B2 (en) * | 1999-01-05 | 2004-06-24 | Trustees Of Boston University | Improved nucleic acid cloning |
| US20040005673A1 (en) * | 2001-06-29 | 2004-01-08 | Kevin Jarrell | System for manipulating nucleic acids |
| WO2002010398A2 (en) | 2000-07-31 | 2002-02-07 | Hahn Frederick M | Manipulation of genes of the mevalonate and isoprenoid pathways to create novel traits in transgenic organisms |
| EP1373476B1 (en) | 2001-03-09 | 2011-06-15 | University Of Kentucky Research Foundation | Cytochrome p450s and uses thereof |
| AU2012202780B2 (en) * | 2001-03-09 | 2014-07-03 | University Of Kentucky Research Foundation | Cytochrome P450s and Uses Thereof |
| AU2013204829B2 (en) * | 2001-03-09 | 2013-07-04 | University Of Kentucky Research Foundation | Cytochrome P450s and uses thereof |
| US7192751B2 (en) * | 2001-12-06 | 2007-03-20 | The Regents Of The University Of California | Biosynthesis of amorpha-4,11-diene |
| US7172886B2 (en) * | 2001-12-06 | 2007-02-06 | The Regents Of The University Of California | Biosynthesis of isopentenyl pyrophosphate |
| US7442785B2 (en) | 2003-07-24 | 2008-10-28 | The University Of Kentucky Research Foundation | Sesquiterpene synthase gene and protein |
| US8124811B2 (en) | 2007-03-20 | 2012-02-28 | Allylix, Inc. | Fragrance and methods for production of 5-epi-β-vetivone, 2-isopropyl-6,10-dimethyl-spiro[4.5]deca-2,6-dien-8-one, and 2-isopropyl-6,10-dimethyl-spiro[4.5]deca-1,6-dien-8-one |
| EP2171085A4 (en) | 2007-06-01 | 2010-07-14 | Sapphire Energy | SCREENING OF GENETICALLY MODIFIED PHOTOSYNTHETIC ORGANISMS WITH HIGH THROUGHPUT |
| MX2010002721A (es) | 2007-09-11 | 2010-06-11 | Sapphire Energy Inc | Metodos para producir productos organicos con organismos fotosinteticos y productos y composiciones de los mismos. |
| CA2698801A1 (en) * | 2007-09-11 | 2009-03-19 | Sapphire Energy, Inc. | Molecule production by photosynthetic organisms |
| KR20100118973A (ko) * | 2007-12-13 | 2010-11-08 | 다니스코 유에스 인크. | 이소프렌을 생성하기 위한 조성물 및 방법 |
| US8034992B2 (en) * | 2008-06-16 | 2011-10-11 | Academia Sinica | Gibberellin 2-oxidase genes and uses thereof |
| US8481286B2 (en) * | 2008-08-12 | 2013-07-09 | Allylix, Inc. | Method for production of isoprenoid compounds |
| EP2633042A1 (en) | 2010-10-29 | 2013-09-04 | Allylix, Inc. | Modified valencene synthase polypeptides, encoding nucleic acid molecules and uses thereof |
| US9550815B2 (en) | 2012-01-23 | 2017-01-24 | University Of British Columbia | ABC terpenoid transporters and methods of using the same |
| JP5950253B2 (ja) * | 2012-02-13 | 2016-07-13 | 住友ゴム工業株式会社 | イソプレノイドの製造方法、及びイソプレノイド |
| WO2014022434A1 (en) | 2012-07-30 | 2014-02-06 | Allylix, Inc. | Sclareol and labdenediol diphosphate synthase polypeptides encoding nucleic acid molecules and uses thereof |
| ES2911701T3 (es) | 2012-11-01 | 2022-05-20 | Univ British Columbia | Polipéptidos de citocromo P450 y citocromo P450 reductasa, moléculas de ácido nucleico codificantes y usos de los mismos |
| ES2647828T3 (es) | 2013-03-14 | 2017-12-26 | Evolva, Inc. | Polipéptidos de valenceno sintasa, moléculas de ácido nucleico que los codifican y usos de los mismos |
| CN111621508B (zh) * | 2020-06-11 | 2022-07-01 | 云南中烟工业有限责任公司 | 烟草萜类合成酶NtTPS7基因及其载体与应用 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2159735A1 (en) * | 1993-04-02 | 1994-10-13 | Terry Euclaire Meyer | Southern corn rootworm control with limonene |
| CA2118071C (en) * | 1993-10-28 | 2004-09-14 | Rodney B. Croteau | Dna encoding limonene synthase from mentha spicata |
| US5824774A (en) * | 1996-04-12 | 1998-10-20 | Board Of Trustees Of The University Of Kentucky | Chimeric isoprenoid synthases and uses thereof |
-
1996
- 1996-04-12 US US08/631,341 patent/US5824774A/en not_active Expired - Lifetime
-
1997
- 1997-04-11 EP EP97921142A patent/EP0904095B1/en not_active Expired - Lifetime
- 1997-04-11 TW TW086104693A patent/TW509724B/zh not_active IP Right Cessation
- 1997-04-11 JP JP9537218A patent/JP2000508899A/ja not_active Withdrawn
- 1997-04-11 IL IL12648697A patent/IL126486A0/xx active IP Right Grant
- 1997-04-11 CA CA002250712A patent/CA2250712C/en not_active Expired - Lifetime
- 1997-04-11 PT PT97921142T patent/PT904095E/pt unknown
- 1997-04-11 TR TR1998/02043T patent/TR199802043T2/xx unknown
- 1997-04-11 EA EA199800917A patent/EA001622B1/ru not_active IP Right Cessation
- 1997-04-11 AP APAP/P/1997/000971A patent/AP808A/en active
- 1997-04-11 KR KR1019980708111A patent/KR20000005385A/ko not_active Application Discontinuation
- 1997-04-11 WO PCT/US1997/005986 patent/WO1997038703A1/en active IP Right Grant
- 1997-04-11 BR BR9708650A patent/BR9708650A/pt not_active Application Discontinuation
- 1997-04-11 ES ES97921142T patent/ES2132046T3/es not_active Expired - Lifetime
- 1997-04-11 IN IN947DE1997 patent/IN186316B/en unknown
- 1997-04-11 DE DE69715192T patent/DE69715192T2/de not_active Expired - Fee Related
- 1997-04-11 AU AU27264/97A patent/AU2726497A/en not_active Abandoned
- 1997-04-11 AT AT97921142T patent/ATE223225T1/de not_active IP Right Cessation
- 1997-04-11 PL PL97329404A patent/PL329404A1/xx unknown
- 1997-04-11 ZA ZA9703108A patent/ZA973108B/xx unknown
- 1997-04-11 CZ CZ19983179A patent/CZ294613B6/cs not_active IP Right Cessation
- 1997-04-11 DE DE0904095T patent/DE904095T1/de active Pending
- 1997-04-11 EP EP02009895A patent/EP1229122A3/en not_active Withdrawn
- 1997-04-14 ID IDP971219A patent/ID19769A/id unknown
- 1997-04-14 AR ARP970101486A patent/AR006638A1/es not_active Application Discontinuation
-
1998
- 1998-08-14 US US09/134,699 patent/US6072045A/en not_active Expired - Lifetime
- 1998-10-08 IL IL126486A patent/IL126486A/en not_active IP Right Cessation
- 1998-10-09 OA OA9800191A patent/OA10895A/en unknown
-
1999
- 1999-01-01 GR GR990300025T patent/GR990300025T1/el unknown
- 1999-06-22 HK HK99102647A patent/HK1017275A1/xx not_active IP Right Cessation
-
2011
- 2011-08-30 JP JP2011186897A patent/JP2012005499A/ja active Pending
-
2014
- 2014-12-24 JP JP2014259849A patent/JP2015057074A/ja active Pending
-
2015
- 2015-07-03 JP JP2015134197A patent/JP2015171387A/ja active Pending
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA | Abandonment or withdrawal |