AR005308A1 - Composiciones farmaceuticas parenterales que constan de sales de alquilamonio de acidos -2- arilpropionicos y procedimiento de preparacion de las mismas - Google Patents

Composiciones farmaceuticas parenterales que constan de sales de alquilamonio de acidos -2- arilpropionicos y procedimiento de preparacion de las mismas

Info

Publication number
AR005308A1
AR005308A1 ARP960105932A ARP960105932A AR005308A1 AR 005308 A1 AR005308 A1 AR 005308A1 AR P960105932 A ARP960105932 A AR P960105932A AR P960105932 A ARP960105932 A AR P960105932A AR 005308 A1 AR005308 A1 AR 005308A1
Authority
AR
Argentina
Prior art keywords
preparation
pharmaceutical compositions
arilpropionicos
procedure
same
Prior art date
Application number
ARP960105932A
Other languages
English (en)
Original Assignee
Dompe Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dompe Spa filed Critical Dompe Spa
Publication of AR005308A1 publication Critical patent/AR005308A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

Composiciones farmacéuticas con actividades antiinflamatorias aptas para el suministro parenteral, las cuales comprenden una sal de alquilamonio de unácido 2-arilpropiónico seleccionado en el grupo formado por cetoprofeno, ibuprofeno,napro xeno, ácido tiaprofénico, tanto en forma racémica como enforma enantiomérica, en una solución acuosa con una osmolaridad incluída entre 270 y 310 mOs/kg y un pH incluido en el intervalo entre 7,0 y 7,5, siendodicha solución carente desustancias con servantes y de sustancias de soporte y siendo preparada y conservada en un ambiente de gas inerte. El procedimientopara la preparación de dichas composiciones incluye disolver oportunamente en agua para preparados inyectables depH incluido entr e 7,0 y 7,5 en atmósfera degas inerte y al amparo de la luz, una sal alquilamónica de un ácido 2-arilpropiónico seleccionado en el grupo formado por cetoprofeno, ibuprofeno,naproxeno y ácido tiaprofénico.
ARP960105932A 1995-12-28 1996-12-27 Composiciones farmaceuticas parenterales que constan de sales de alquilamonio de acidos -2- arilpropionicos y procedimiento de preparacion de las mismas AR005308A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT95MI002777A IT1277741B1 (it) 1995-12-28 1995-12-28 Composizioni farmaceutiche parenterali contenenti sali di alchilammonio di acidi 2-arilpropionici

Publications (1)

Publication Number Publication Date
AR005308A1 true AR005308A1 (es) 1999-04-28

Family

ID=11372830

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP960105932A AR005308A1 (es) 1995-12-28 1996-12-27 Composiciones farmaceuticas parenterales que constan de sales de alquilamonio de acidos -2- arilpropionicos y procedimiento de preparacion de las mismas

Country Status (24)

Country Link
US (1) US5895789A (es)
EP (1) EP0814797B1 (es)
KR (1) KR19980702301A (es)
CN (1) CN1082812C (es)
AR (1) AR005308A1 (es)
AT (1) ATE232096T1 (es)
AU (1) AU1069897A (es)
BR (1) BR9607422A (es)
CA (1) CA2213232A1 (es)
CZ (1) CZ290646B6 (es)
DE (1) DE69626103T2 (es)
DK (1) DK0814797T3 (es)
EA (1) EA000599B1 (es)
ES (1) ES2192234T3 (es)
HK (1) HK1008777A1 (es)
HU (1) HU224685B1 (es)
IT (1) IT1277741B1 (es)
NO (1) NO973921L (es)
PL (1) PL187170B1 (es)
PT (1) PT814797E (es)
SI (1) SI9620023A (es)
SK (1) SK282579B6 (es)
TR (1) TR199700869T1 (es)
WO (1) WO1997024114A1 (es)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1298214B1 (it) * 1998-01-28 1999-12-20 Dompe Spa Sali dell'acido (r) 2-(3-benzoilfenil) propionico e loro composizioni farmaceutiche.
EP1284729A4 (en) * 2000-04-13 2007-12-19 Mayo Foundation REDUCTION AGENTS OF A (BETA) 42
US6342530B1 (en) 2000-11-14 2002-01-29 Farmacon-Il, Llc Composition and method for parenteral administration of ibuprofen d,l- or l-lysine salt
US6344479B1 (en) 2001-03-20 2002-02-05 Farmacon-Il, Llc Method of preventing retinopathy of prematurity in a neonate
US20040132823A1 (en) * 2001-11-02 2004-07-08 Leo Pavliv Pharmaceutical composition of 2-(4-isobutylphenyl) propionic acid
ES2189682B1 (es) * 2001-12-11 2004-04-01 Laboratorios Del Dr. Esteve, S.A. Preparacion bebible que comprende ketoprofeno y su empleo en el tratamiento de procesos que cursan con fiebre, inflamacion y/o dolor, en un colectivo de animales, de forma simultanea.
ES2287519T3 (es) * 2002-10-25 2007-12-16 Dompe S.P.A. Composiciones inyectables indoloras que contienen sal de acidos 2-arilpropionicos.
US7090859B2 (en) * 2002-12-13 2006-08-15 Ronald Thomas Haas Ketoprofen compositions and methods of making them
WO2004071431A2 (en) * 2003-02-05 2004-08-26 Myriad Genetics, Inc. Method and composition for treating neurodegenerative disorders
KR20060040676A (ko) * 2003-07-11 2006-05-10 미리어드 제네틱스, 인크. 알츠하이머병을 치료하기 위한 약제학적 방법, 투약 방법및 제형
US20070293538A1 (en) * 2004-04-13 2007-12-20 Myriad Genetics, Incorporated Pharmaceutical Composition And Methods For Treating Neurodegenerative Disorders
US20050252144A1 (en) * 2004-04-29 2005-11-17 Macdonald Robert A Veneers for walls, retaining walls and the like
BRPI0514303A (pt) * 2004-08-11 2008-06-10 Myriad Genetics Inc composição farmacêutica e método para tratar distúrbios neurodegenerativos
WO2006020850A2 (en) * 2004-08-11 2006-02-23 Myriad Genetics, Inc. Pharmaceutical composition and method for treating neurodegenerative disorders
WO2006020852A2 (en) * 2004-08-11 2006-02-23 Myriad Genetics, Inc. Pharmaceutical composition and method for treating neurodegenerative disorders
EP1893190A4 (en) * 2005-04-28 2010-07-28 Theraquest Biosciences Llc METHODS AND COMPOSITIONS FOR TREATING PAIN
AU2006272760A1 (en) * 2005-07-22 2007-02-01 Myriad Genetics, Inc. High drug load formulations and dosage forms
MX2008010101A (es) * 2006-02-06 2009-02-27 Pharmaceutical Solutions Inc Preparaciones antiinflamatorias no esteroides orales líquidas y en polvo para administración en animales.
ATE486593T1 (de) * 2006-03-16 2010-11-15 Novartis Ag Feste dosierungsform mit einem wirkstoff mit unterdrücktem geschmack
WO2008006099A2 (en) * 2006-07-07 2008-01-10 Myriad Genetics, Inc. Treatment of psychiatric disorders
FR2950533B1 (fr) 2009-09-28 2012-01-13 Maco Pharma Sa Formulation liquide, stable, prete a l'emploi de ketoprofene
FR2971712B1 (fr) * 2011-02-22 2016-06-10 Map France Solution stable de ketoprofene pour injection intraveineuse
US8415337B1 (en) 2011-03-06 2013-04-09 Recordati Rare Diseases Inc. Ibuprofen compositions and methods of making same
CN102381986A (zh) * 2011-07-25 2012-03-21 南京特丰药业股份有限公司 一种右旋布洛芬氨丁三醇盐及其口服溶液的制备方法
EP2739266B1 (en) * 2011-08-04 2016-07-27 Omeros Corporation Stable anti-inflammatory solutions for injection
CN102362857A (zh) * 2011-11-22 2012-02-29 陆荣政 一种右旋布洛芬注射液及其制备方法
GR1008942B (el) * 2015-10-14 2017-02-06 ΙΟΥΛΙΑ ΚΑΙ ΕΙΡΗΝΗ ΤΣΕΤΗ ΦΑΡΜΑΚΕΥΤΙΚΑ ΕΡΓΑΣΤΗΡΙΑ ΑΒΕΕ με δ.τ. "INTERMED ΑΒΕΕ" Μεθοδος παραγωγης σταθερου υδατικου διαλυματος λυσινικης ιμπουπροφαινης για ενδοκολπικη χρηση
EA202091229A1 (ru) 2017-11-30 2020-08-19 Ацьенде Кимике Рьюните Анджелини Франческо А.К.Р.А.Ф. С.П.А. Стабильная жидкая композиция кетопрофена, его солей и энантиомеров

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1497044A (en) * 1974-03-07 1978-01-05 Prodotti Antibiotici Spa Salts of phenyl-alkanoic acids
DE2830921A1 (de) * 1978-07-14 1980-01-31 Bbc Brown Boveri & Cie Verfahren zum verhindern von sintererscheinungen an schmiedebloeckchen
HU185926B (en) * 1979-09-27 1985-04-28 Agostne Kahan Process for preparing water soluble derivatives of non-steroid antiinflammatory compositions and pharmaceutical compositins containing such derivatives
EP0070714B1 (en) * 1981-07-20 1986-05-07 The Upjohn Company Use of ibuprofen or flurbiprofen for the manufacture of a medicament for treating respiratory disorders
DE3328401A1 (de) * 1983-08-05 1985-02-21 Merckle GmbH, 7902 Blaubeuren Injizierbare loesung zur behandlung von entzuendungen
EP0267321B1 (de) * 1986-11-14 1990-02-28 MEDICEChem.-Pharm. Fabrik Pütter GmbH & Co. KG Ibuprofen enthaltendes Arzneimittel
US4868214A (en) * 1987-11-17 1989-09-19 Analgesic Associates Onset-hastened/enhanced analgesia
US4887620A (en) * 1988-04-26 1989-12-19 Better Life International, Inc. Composition and method to provide organoleptic bite in a composition for human consumption
IT1255007B (it) * 1991-07-01 1995-10-11 Altergon Sa Sale solubile dell'ibuprofen c0n n-(2-idrossietil) pirrolidina e composizioni farmaceutiche che li contengono.
FR2687915B1 (fr) * 1992-02-28 1995-05-05 Rhone Poulenc Rorer Sa Composition pharmaceutique utilisable comme analgesique contenant l'acide (benzoyl-3 phenyl)-2 propionique-(r).
US5331000A (en) * 1992-03-09 1994-07-19 Sepracor Inc. Antipyretic and analgesic methods and compositions containing optically pure R(-) ketoprofen
AU6290594A (en) * 1993-03-09 1994-09-26 Dompe Farmaceutici S.P.A. Salts of 2-(3-benzoylphenyl)propionic acid with achiral and chiral organic bases and pharmaceutical compositions thereof

Also Published As

Publication number Publication date
SI9620023A (sl) 1998-02-28
ITMI952777A1 (it) 1997-06-28
TR199700869T1 (xx) 1997-12-21
US5895789A (en) 1999-04-20
CN1176596A (zh) 1998-03-18
CA2213232A1 (en) 1997-07-10
CZ290646B6 (cs) 2002-09-11
EA000599B1 (ru) 1999-12-29
DE69626103D1 (de) 2003-03-13
ES2192234T3 (es) 2003-10-01
ITMI952777A0 (es) 1995-12-28
EP0814797B1 (en) 2003-02-05
HUP9801048A3 (en) 2000-07-28
BR9607422A (pt) 1998-06-23
HUP9801048A1 (hu) 1998-10-28
PL187170B1 (pl) 2004-05-31
CZ264397A3 (en) 1997-11-12
SK113097A3 (en) 1998-02-04
IT1277741B1 (it) 1997-11-12
HU224685B1 (hu) 2005-12-28
HK1008777A1 (en) 1999-07-16
PT814797E (pt) 2003-06-30
NO973921D0 (no) 1997-08-26
NO973921L (no) 1997-08-26
KR19980702301A (ko) 1998-07-15
DE69626103T2 (de) 2003-12-04
DK0814797T3 (da) 2003-05-26
PL322165A1 (en) 1998-01-19
ATE232096T1 (de) 2003-02-15
EP0814797A1 (en) 1998-01-07
SK282579B6 (sk) 2002-10-08
WO1997024114A1 (en) 1997-07-10
AU1069897A (en) 1997-07-28
EA199700201A1 (ru) 1998-02-26
CN1082812C (zh) 2002-04-17
MX9706237A (es) 1997-11-29

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