ZA894913B - Heterocyclic compounds - Google Patents

Heterocyclic compounds

Info

Publication number
ZA894913B
ZA894913B ZA894913A ZA894913A ZA894913B ZA 894913 B ZA894913 B ZA 894913B ZA 894913 A ZA894913 A ZA 894913A ZA 894913 A ZA894913 A ZA 894913A ZA 894913 B ZA894913 B ZA 894913B
Authority
ZA
South Africa
Prior art keywords
alkyl
thiazole
optionally substituted
alkynyl
alkylene
Prior art date
Application number
ZA894913A
Other languages
English (en)
Inventor
Thomas Geoffrey Colerick Bird
Geoffrey Colerick Bird Thomas
Graham Charles Crawley
Charles Crawley Graham
Martin Paul Edwards
Paul Edwards Martin
Philip Neil Ekwards
Neil Ekwards Philip
Jean-Marck Marie Maur Girodeau
Marie Maurice Girod Jean-Marck
John Francis Kingston
Francis Kingston John
Original Assignee
Ici Pharma
Ici Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ici Pharma, Ici Plc filed Critical Ici Pharma
Publication of ZA894913B publication Critical patent/ZA894913B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D277/24—Radicals substituted by oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • Detergent Compositions (AREA)
  • Air Bags (AREA)
ZA894913A 1988-07-12 1989-06-28 Heterocyclic compounds ZA894913B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP88401816 1988-07-12

Publications (1)

Publication Number Publication Date
ZA894913B true ZA894913B (en) 1990-03-28

Family

ID=8200404

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA894913A ZA894913B (en) 1988-07-12 1989-06-28 Heterocyclic compounds

Country Status (14)

Country Link
US (1) US5089513A (xx)
EP (1) EP0351194B1 (xx)
JP (1) JPH0276864A (xx)
AT (1) ATE107294T1 (xx)
AU (1) AU618610B2 (xx)
DE (1) DE68916119T2 (xx)
DK (1) DK346089A (xx)
ES (1) ES2055791T3 (xx)
FI (1) FI893381A (xx)
IE (1) IE63681B1 (xx)
NO (1) NO892823L (xx)
NZ (1) NZ229761A (xx)
PT (1) PT91123B (xx)
ZA (1) ZA894913B (xx)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5236919A (en) * 1989-02-28 1993-08-17 Imperial Chemical Industries Plc Quinoxalinyl derivatives suitable for use in leukotriene mediated disease
JPH03173874A (ja) * 1989-09-29 1991-07-29 Mitsubishi Kasei Corp 新規複素環化合物
US5254581A (en) * 1990-06-21 1993-10-19 Imperial Chemical Industries Plc Pyran derivatives and their use as inhibitors of 5-lipoxygenase
IE914005A1 (en) * 1990-12-14 1992-06-17 Zeneca Ltd Novel intermediates
DE4139751A1 (de) * 1991-12-03 1993-06-09 Bayer Ag, 5090 Leverkusen, De Thiazolyl substituierte chinolylmethoxyphenylessigsaeurederivate
US5281720A (en) * 1991-02-28 1994-01-25 Merck Frosst Canada, Inc. Pyranylphenyl hydroxyalkylnaphthoic acids as inhibitors of leukotriene biosynthesis
NZ249286A (en) * 1992-02-13 1996-02-27 Merrell Dow Pharma Piperidine-4-ylmethyl thiophene and thiazole derivatives and pharmaceutical compositions
US5308852A (en) * 1992-06-29 1994-05-03 Merck Frosst Canada, Inc. Heteroarylnaphthalenes as inhibitors of leukotriene biosynthesis
US5428060A (en) * 1992-08-27 1995-06-27 Merck Frosst Canada, Inc. Heteroarylnaphthalene lactones as inhibitors of leukotriene biosynthesis
US5350744A (en) * 1992-08-27 1994-09-27 Merck Frosst Canada, Inc. Phenylnaphthalene lactones as inhibitors of leukotriene biosynthesis
US5426109A (en) * 1992-08-27 1995-06-20 Merck Frosst Canada, Inc. Phenylnaphthalene hydroxy acids
US5252599A (en) * 1992-08-27 1993-10-12 Merck Frosst Canada, Inc. Heteroarylnaphthalene hydroxy acids as inhibitors of leukotriene biosynthesis
US5458793A (en) * 1993-05-13 1995-10-17 The Lubrizol Corporation Compositions useful as additives for lubricants and liquid fuels
CN1107059C (zh) * 1994-10-14 2003-04-30 山之内制药株式会社 吡咯衍生物
US5527827A (en) * 1994-10-27 1996-06-18 Merck Frosst Canada, Inc. Bisarylcarbinol cinnamic acids as inhibitors of leukotriene biosynthesis
SE9804212D0 (sv) * 1998-12-04 1998-12-04 Astra Pharma Prod Compounds
AR031722A1 (es) * 2000-10-03 2003-10-01 Syngenta Participations Ag Fenilalquinos herbicidamente activos, proceso para su preparacion, composicion herbicida e inhibidora del crecimiento de las plantas, procedimiento para el control del crecimiento indeseado de las plantas, y procedimiento para inhibir el crecimiento de las plantas
US6825221B2 (en) 2001-10-18 2004-11-30 Allergan, Inc. Arylsulfanyl and heteroarylsulfanyl derivatives for treating pain
WO2010128388A2 (en) * 2009-05-08 2010-11-11 Aurobindo Pharma Limited An improved process for the preparation of intermediate compounds useful for the preparation of cinacalcet
EP3431084A1 (en) 2009-10-02 2019-01-23 Avexxin AS Antiinflammatory 2-oxothiazoles
EP2530078A1 (en) 2010-01-27 2012-12-05 Takeda Pharmaceutical Company Limited Thiazole derivative
EP2951164B1 (en) 2013-01-29 2019-06-05 Avexxin AS Antiinflammatory and antitumor 2-oxothiazoles compounds
CA2945674A1 (en) * 2014-04-15 2015-10-22 Dow Agrosciences Llc Metalloenzyme inhibitor compounds as fungicides
GB201413695D0 (en) 2014-08-01 2014-09-17 Avexxin As Compound
GB201604318D0 (en) 2016-03-14 2016-04-27 Avexxin As Combination therapy

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5835178A (ja) * 1981-08-26 1983-03-01 Santen Pharmaceut Co Ltd チアゾリジン環を有するカルボン酸類
JPS5841872A (ja) * 1981-09-04 1983-03-11 Santen Pharmaceut Co Ltd チアゾリジン環を有するエ−テル類
IE56702B1 (en) * 1982-12-01 1991-11-06 Usv Pharma Corp Antiinflammatory antiallergic compounds
US4567184A (en) * 1982-12-01 1986-01-28 Usv Pharmaceutical Corporation Certain aryl or hetero-aryl derivatives of 1-hydroxy-pentane or 1-hydroxy-hexane which are useful for treating inflammation and allergies
US4778931A (en) * 1982-12-01 1988-10-18 Usv Pharmaceutical Corporation Certain [3-(1-hydroxy hexyl-tetrahydro)naphthalenes], the corresponding naphthalenes having anti-inflammatory and anti-allergic activity
US4794188A (en) * 1982-12-01 1988-12-27 Usv Pharmaceutical Corporation Certain unsymmetrical quinolinyl ethers having anti-inflammatory and anti-allergic activity
US4644009A (en) * 1984-10-29 1987-02-17 Usv Pharmaceutical Corporation Aryl-alkyl heterocyclic compounds
NZ213986A (en) * 1984-10-30 1989-07-27 Usv Pharma Corp Heterocyclic or aromatic compounds, and pharmaceutical compositions containing such
US4839369A (en) * 1985-04-16 1989-06-13 Rorer Pharmaceutical Corporation Aryl and heteroaryl ethers as agents for the treatment of hypersensitive ailments
US4631287A (en) * 1985-04-16 1986-12-23 Usv Pharmaceutical Corp. Aryl and heteroaryl ethers as agents for the treatment of hypersensitive ailments
US4725619A (en) * 1985-04-16 1988-02-16 Usv Pharmaceutical Corporation Aryl and heteroaryl ethers as agents for the treatment of hypersensitive ailments
US4728668A (en) * 1985-04-16 1988-03-01 Usv Pharmaceutical Corporation Aryl and heteroaryl ethers as agents for the treatment of hypersensitive ailments
US4677210A (en) * 1985-06-19 1987-06-30 Rorer Pharmaceutical Corporation 1-arylalkoxy- and 1-arylalkylthioaryl-2-pyrazolines as anti-inflammatory or anti-allergic agents
JPS62142168A (ja) * 1985-10-16 1987-06-25 Mitsubishi Chem Ind Ltd チアゾ−ル誘導体及びそれを有効成分とするロイコトリエンきつ抗剤
US4868193A (en) * 1986-09-24 1989-09-19 Rorer Pharmaceutical Corporation Styryl tetrazoles and anti-allergic use thereof
DE3783105T2 (de) * 1986-03-13 1993-04-22 Rhone Poulenc Rorer Int Chinolinylaether tetrazole als mittel zur behandlung von hyperempfindlichen krankheiten.
US4668694A (en) * 1986-04-22 1987-05-26 Usv Pharmaceutical Corporation 1-arylalkoxyphenyl-pyrazolines, ketones or enoles as anti-inflammatory or anti-allergic agents
US4874777A (en) * 1987-04-10 1989-10-17 Eli Lilly And Company Leukotriene antagonists

Also Published As

Publication number Publication date
FI893381A (fi) 1990-01-13
DE68916119D1 (de) 1994-07-21
PT91123B (pt) 1995-01-31
PT91123A (pt) 1990-02-08
IE892232L (en) 1990-01-12
AU618610B2 (en) 1992-01-02
FI893381A0 (fi) 1989-07-12
NO892823D0 (no) 1989-07-07
NZ229761A (en) 1991-10-25
EP0351194A2 (en) 1990-01-17
DE68916119T2 (de) 1994-09-22
US5089513A (en) 1992-02-18
AU3801489A (en) 1990-01-18
EP0351194B1 (en) 1994-06-15
DK346089A (da) 1990-01-13
EP0351194A3 (en) 1990-06-27
NO892823L (no) 1990-01-15
ES2055791T3 (es) 1994-09-01
DK346089D0 (da) 1989-07-12
JPH0276864A (ja) 1990-03-16
IE63681B1 (en) 1995-05-31
ATE107294T1 (de) 1994-07-15

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