ZA894913B - Heterocyclic compounds - Google Patents
Heterocyclic compoundsInfo
- Publication number
- ZA894913B ZA894913B ZA894913A ZA894913A ZA894913B ZA 894913 B ZA894913 B ZA 894913B ZA 894913 A ZA894913 A ZA 894913A ZA 894913 A ZA894913 A ZA 894913A ZA 894913 B ZA894913 B ZA 894913B
- Authority
- ZA
- South Africa
- Prior art keywords
- alkyl
- thiazole
- optionally substituted
- alkynyl
- alkylene
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D277/24—Radicals substituted by oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Separation Using Semi-Permeable Membranes (AREA)
- Detergent Compositions (AREA)
- Air Bags (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP88401816 | 1988-07-12 |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA894913B true ZA894913B (en) | 1990-03-28 |
Family
ID=8200404
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA894913A ZA894913B (en) | 1988-07-12 | 1989-06-28 | Heterocyclic compounds |
Country Status (14)
Country | Link |
---|---|
US (1) | US5089513A (xx) |
EP (1) | EP0351194B1 (xx) |
JP (1) | JPH0276864A (xx) |
AT (1) | ATE107294T1 (xx) |
AU (1) | AU618610B2 (xx) |
DE (1) | DE68916119T2 (xx) |
DK (1) | DK346089A (xx) |
ES (1) | ES2055791T3 (xx) |
FI (1) | FI893381A (xx) |
IE (1) | IE63681B1 (xx) |
NO (1) | NO892823L (xx) |
NZ (1) | NZ229761A (xx) |
PT (1) | PT91123B (xx) |
ZA (1) | ZA894913B (xx) |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5236919A (en) * | 1989-02-28 | 1993-08-17 | Imperial Chemical Industries Plc | Quinoxalinyl derivatives suitable for use in leukotriene mediated disease |
JPH03173874A (ja) * | 1989-09-29 | 1991-07-29 | Mitsubishi Kasei Corp | 新規複素環化合物 |
US5254581A (en) * | 1990-06-21 | 1993-10-19 | Imperial Chemical Industries Plc | Pyran derivatives and their use as inhibitors of 5-lipoxygenase |
IE914005A1 (en) * | 1990-12-14 | 1992-06-17 | Zeneca Ltd | Novel intermediates |
DE4139751A1 (de) * | 1991-12-03 | 1993-06-09 | Bayer Ag, 5090 Leverkusen, De | Thiazolyl substituierte chinolylmethoxyphenylessigsaeurederivate |
US5281720A (en) * | 1991-02-28 | 1994-01-25 | Merck Frosst Canada, Inc. | Pyranylphenyl hydroxyalkylnaphthoic acids as inhibitors of leukotriene biosynthesis |
NZ249286A (en) * | 1992-02-13 | 1996-02-27 | Merrell Dow Pharma | Piperidine-4-ylmethyl thiophene and thiazole derivatives and pharmaceutical compositions |
US5308852A (en) * | 1992-06-29 | 1994-05-03 | Merck Frosst Canada, Inc. | Heteroarylnaphthalenes as inhibitors of leukotriene biosynthesis |
US5428060A (en) * | 1992-08-27 | 1995-06-27 | Merck Frosst Canada, Inc. | Heteroarylnaphthalene lactones as inhibitors of leukotriene biosynthesis |
US5350744A (en) * | 1992-08-27 | 1994-09-27 | Merck Frosst Canada, Inc. | Phenylnaphthalene lactones as inhibitors of leukotriene biosynthesis |
US5426109A (en) * | 1992-08-27 | 1995-06-20 | Merck Frosst Canada, Inc. | Phenylnaphthalene hydroxy acids |
US5252599A (en) * | 1992-08-27 | 1993-10-12 | Merck Frosst Canada, Inc. | Heteroarylnaphthalene hydroxy acids as inhibitors of leukotriene biosynthesis |
US5458793A (en) * | 1993-05-13 | 1995-10-17 | The Lubrizol Corporation | Compositions useful as additives for lubricants and liquid fuels |
CN1107059C (zh) * | 1994-10-14 | 2003-04-30 | 山之内制药株式会社 | 吡咯衍生物 |
US5527827A (en) * | 1994-10-27 | 1996-06-18 | Merck Frosst Canada, Inc. | Bisarylcarbinol cinnamic acids as inhibitors of leukotriene biosynthesis |
SE9804212D0 (sv) * | 1998-12-04 | 1998-12-04 | Astra Pharma Prod | Compounds |
AR031722A1 (es) * | 2000-10-03 | 2003-10-01 | Syngenta Participations Ag | Fenilalquinos herbicidamente activos, proceso para su preparacion, composicion herbicida e inhibidora del crecimiento de las plantas, procedimiento para el control del crecimiento indeseado de las plantas, y procedimiento para inhibir el crecimiento de las plantas |
US6825221B2 (en) | 2001-10-18 | 2004-11-30 | Allergan, Inc. | Arylsulfanyl and heteroarylsulfanyl derivatives for treating pain |
WO2010128388A2 (en) * | 2009-05-08 | 2010-11-11 | Aurobindo Pharma Limited | An improved process for the preparation of intermediate compounds useful for the preparation of cinacalcet |
EP3431084A1 (en) | 2009-10-02 | 2019-01-23 | Avexxin AS | Antiinflammatory 2-oxothiazoles |
EP2530078A1 (en) | 2010-01-27 | 2012-12-05 | Takeda Pharmaceutical Company Limited | Thiazole derivative |
EP2951164B1 (en) | 2013-01-29 | 2019-06-05 | Avexxin AS | Antiinflammatory and antitumor 2-oxothiazoles compounds |
CA2945674A1 (en) * | 2014-04-15 | 2015-10-22 | Dow Agrosciences Llc | Metalloenzyme inhibitor compounds as fungicides |
GB201413695D0 (en) | 2014-08-01 | 2014-09-17 | Avexxin As | Compound |
GB201604318D0 (en) | 2016-03-14 | 2016-04-27 | Avexxin As | Combination therapy |
Family Cites Families (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5835178A (ja) * | 1981-08-26 | 1983-03-01 | Santen Pharmaceut Co Ltd | チアゾリジン環を有するカルボン酸類 |
JPS5841872A (ja) * | 1981-09-04 | 1983-03-11 | Santen Pharmaceut Co Ltd | チアゾリジン環を有するエ−テル類 |
IE56702B1 (en) * | 1982-12-01 | 1991-11-06 | Usv Pharma Corp | Antiinflammatory antiallergic compounds |
US4567184A (en) * | 1982-12-01 | 1986-01-28 | Usv Pharmaceutical Corporation | Certain aryl or hetero-aryl derivatives of 1-hydroxy-pentane or 1-hydroxy-hexane which are useful for treating inflammation and allergies |
US4778931A (en) * | 1982-12-01 | 1988-10-18 | Usv Pharmaceutical Corporation | Certain [3-(1-hydroxy hexyl-tetrahydro)naphthalenes], the corresponding naphthalenes having anti-inflammatory and anti-allergic activity |
US4794188A (en) * | 1982-12-01 | 1988-12-27 | Usv Pharmaceutical Corporation | Certain unsymmetrical quinolinyl ethers having anti-inflammatory and anti-allergic activity |
US4644009A (en) * | 1984-10-29 | 1987-02-17 | Usv Pharmaceutical Corporation | Aryl-alkyl heterocyclic compounds |
NZ213986A (en) * | 1984-10-30 | 1989-07-27 | Usv Pharma Corp | Heterocyclic or aromatic compounds, and pharmaceutical compositions containing such |
US4839369A (en) * | 1985-04-16 | 1989-06-13 | Rorer Pharmaceutical Corporation | Aryl and heteroaryl ethers as agents for the treatment of hypersensitive ailments |
US4631287A (en) * | 1985-04-16 | 1986-12-23 | Usv Pharmaceutical Corp. | Aryl and heteroaryl ethers as agents for the treatment of hypersensitive ailments |
US4725619A (en) * | 1985-04-16 | 1988-02-16 | Usv Pharmaceutical Corporation | Aryl and heteroaryl ethers as agents for the treatment of hypersensitive ailments |
US4728668A (en) * | 1985-04-16 | 1988-03-01 | Usv Pharmaceutical Corporation | Aryl and heteroaryl ethers as agents for the treatment of hypersensitive ailments |
US4677210A (en) * | 1985-06-19 | 1987-06-30 | Rorer Pharmaceutical Corporation | 1-arylalkoxy- and 1-arylalkylthioaryl-2-pyrazolines as anti-inflammatory or anti-allergic agents |
JPS62142168A (ja) * | 1985-10-16 | 1987-06-25 | Mitsubishi Chem Ind Ltd | チアゾ−ル誘導体及びそれを有効成分とするロイコトリエンきつ抗剤 |
US4868193A (en) * | 1986-09-24 | 1989-09-19 | Rorer Pharmaceutical Corporation | Styryl tetrazoles and anti-allergic use thereof |
DE3783105T2 (de) * | 1986-03-13 | 1993-04-22 | Rhone Poulenc Rorer Int | Chinolinylaether tetrazole als mittel zur behandlung von hyperempfindlichen krankheiten. |
US4668694A (en) * | 1986-04-22 | 1987-05-26 | Usv Pharmaceutical Corporation | 1-arylalkoxyphenyl-pyrazolines, ketones or enoles as anti-inflammatory or anti-allergic agents |
US4874777A (en) * | 1987-04-10 | 1989-10-17 | Eli Lilly And Company | Leukotriene antagonists |
-
1989
- 1989-06-28 NZ NZ229761A patent/NZ229761A/en unknown
- 1989-06-28 ZA ZA894913A patent/ZA894913B/xx unknown
- 1989-07-07 NO NO89892823A patent/NO892823L/no unknown
- 1989-07-11 US US07/378,163 patent/US5089513A/en not_active Expired - Fee Related
- 1989-07-11 EP EP89307041A patent/EP0351194B1/en not_active Expired - Lifetime
- 1989-07-11 PT PT91123A patent/PT91123B/pt not_active IP Right Cessation
- 1989-07-11 AT AT89307041T patent/ATE107294T1/de not_active IP Right Cessation
- 1989-07-11 DE DE68916119T patent/DE68916119T2/de not_active Expired - Fee Related
- 1989-07-11 IE IE223289A patent/IE63681B1/en not_active IP Right Cessation
- 1989-07-11 ES ES89307041T patent/ES2055791T3/es not_active Expired - Lifetime
- 1989-07-11 AU AU38014/89A patent/AU618610B2/en not_active Ceased
- 1989-07-12 JP JP1178206A patent/JPH0276864A/ja active Pending
- 1989-07-12 DK DK346089A patent/DK346089A/da not_active Application Discontinuation
- 1989-07-12 FI FI893381A patent/FI893381A/fi not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
FI893381A (fi) | 1990-01-13 |
DE68916119D1 (de) | 1994-07-21 |
PT91123B (pt) | 1995-01-31 |
PT91123A (pt) | 1990-02-08 |
IE892232L (en) | 1990-01-12 |
AU618610B2 (en) | 1992-01-02 |
FI893381A0 (fi) | 1989-07-12 |
NO892823D0 (no) | 1989-07-07 |
NZ229761A (en) | 1991-10-25 |
EP0351194A2 (en) | 1990-01-17 |
DE68916119T2 (de) | 1994-09-22 |
US5089513A (en) | 1992-02-18 |
AU3801489A (en) | 1990-01-18 |
EP0351194B1 (en) | 1994-06-15 |
DK346089A (da) | 1990-01-13 |
EP0351194A3 (en) | 1990-06-27 |
NO892823L (no) | 1990-01-15 |
ES2055791T3 (es) | 1994-09-01 |
DK346089D0 (da) | 1989-07-12 |
JPH0276864A (ja) | 1990-03-16 |
IE63681B1 (en) | 1995-05-31 |
ATE107294T1 (de) | 1994-07-15 |
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