WO2015006895A1 - 一种生发中药制剂的配方及制备方法 - Google Patents
一种生发中药制剂的配方及制备方法 Download PDFInfo
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- WO2015006895A1 WO2015006895A1 PCT/CN2013/079356 CN2013079356W WO2015006895A1 WO 2015006895 A1 WO2015006895 A1 WO 2015006895A1 CN 2013079356 W CN2013079356 W CN 2013079356W WO 2015006895 A1 WO2015006895 A1 WO 2015006895A1
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- Prior art keywords
- preparation
- hair
- seed oil
- turmeric
- tea seed
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/58—Reptiles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/63—Arthropods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/282—Artemisia, e.g. wormwood or sagebrush
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/60—Moraceae (Mulberry family), e.g. breadfruit or fig
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/752—Citrus, e.g. lime, orange or lemon
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/906—Zingiberaceae (Ginger family)
- A61K36/9068—Zingiber, e.g. garden ginger
Definitions
- the invention relates to a traditional Chinese medicine preparation for germinating action, in particular to a traditional Chinese medicine preparation and a preparation method relating to the hair growth effect.
- the object of the present invention is to provide a traditional Chinese medicine preparation for germinating effect on the basis of the above-mentioned deficiencies, combined with modern Chinese and Western medicine technology, and in particular to provide such a preparation for promoting hair growth and a preparation method thereof.
- the preparation can be applied to the scalp of various characteristics. After washing the hair, there is no allergic reaction, no toxic and side effects, so that the drug can It quickly penetrates into the skin to achieve the purpose of hair growth, and the cost is low, and the preparation process is simple and easy.
- the technical solution of the present invention is as follows:
- the preparation of the invention is made up of tea seed oil, ginger juice, black pig bile, capillaris, earthworm, koji, safflower, smashed, orange nucleus, medlar, medlar, mulberry leaf, Equisetum, viper a paste preparation prepared from Eucommia, Eucommia, Basil, Spatholobus, and turmeric,
- the mass ratio of each component is:
- the preferred raw material quality ratio of the present invention is: Tea seed oil Ginger juice Black pig bile Yin Chen Earthworm Kochia scoparia
- the present invention may also preferably optimize the quality of the raw materials with tea seed oil, ginger juice, black pig bile Earthworm 30g Kochia scoparia 20g Ramen 15g smashed 25g orange nucleus 20g ⁇ 3 scorpion 30g mulberry 40g sage 40g snake scorpion 30g eucommia 40g scorpion 40g spatholobus 40g turmeric 18g t above raw hair Chinese medicine preparation
- the preparation method comprises the following steps:
- tea seed oil in a wok and heat it to 90-120 degrees Celsius, then put the powder of capillaris, earthworm, Kochia scoparia, safflower, smashed, orange kernel, and simmer into the pan. Deep-fried with tea seed oil, take out the oil after 15 minutes;
- the paste preparation in the above step 3) is added to the remaining hazelnut, mulberry leaf, Equisetum, Viper, Eucommia, Basil, Spatholobus, turmeric mixture, and then stirred evenly; The bell, finally installed in a porcelain jar, is ready.
- tea seed oil also known as camellia oil, wild camellia oil, camellia seed oil
- tea seed oil is a unique woody oil in China, its fatty acid composition and the world's best recognized vegetable oil olive oil Similarly, there is the name of "Oriental Olive Oil”.
- Tea oil contains a variety of functional ingredients, with obvious effects of preventing cardiovascular cirrhosis, promoting metabolism, lowering blood pressure, lowering blood fat, and the special effects of anti-cancer and anti-cancer. Ginger juice is washed by the Zingiber officinale Rose. It is smashed and the juice is taken.
- Black pig bile is a very good Chinese herbal medicine, Chinese medicine to treat a variety of diseases, the main components of juice are bile acids, bile pigments, mucin, lipids and inorganic substances. It tastes bitter, cold and salty; it can relieve phlegm and relieve cough and relieve asthma, and benefit the lungs, tonifying the spleen and moistening dryness.
- Yinchen also known as Yinchenhao, Yinchen English name Capi llary Wormwood Herb, Chun was born because of Chen Gen, hence the name is Chen or Yinchen.
- Lamb also known as yellow azalea, yellow azalea, is a member of the genus Rhododendron of the family Ericaceae. It is one of the famous poisonous plants. It is a common Chinese herbal medicine and is often used as an anesthetic and analgesic in medicine. It can treat rheumatoid arthritis and bruises. Drynaria, minced meat, stone rock ginger, monkey ginger, hair ginger, Shen Jiang, climbing rock ginger, rock and ginger, English name Rhizoma Drynariae, bitter, warm. Return to the kidney, liver. It can strengthen the kidney and strengthen the bones.
- Orange nucleus also known as orange nucleus, orange kernel, orange rice, is the seed of the plant ripe fruit of Citrus tangerina Hort. et Tanaka or C. erythrosa Tanaka, which is prolific in Fujian, Zhejiang. In Guangdong, Guangxi, Jiangxi, Hunan, Guizhou, Yunnan, Sichuan and other places, collect the seeds after eating, wash, dry, and use.
- Mulberry leaves are the dry leaves of the mulberry plant, also known as mulberry, mulberry, mulberry, and yellow mulberry. They are produced in most parts of the country and have the functions of lowering blood pressure, blood fat, anti-inflammatory, etc., and can evacuate wind and heat. Qingfei Runzao, calming liver and yang, clearing liver and eyesight, cooling blood to stop bleeding.
- Equisetum perennial erect herb, high 0.5 to 2 meters. Stems hollow and knotted, internodes 2 to 6 cm long, with longitudinal ribs on the surface, rough, degenerated leaves and stalks, sporangium stalks oblong, yellow, stalk apex, densely lanceolate. Like to be born in the river beach, the riverside and other wet places. Cut in summer and autumn, remove impurities, dry or dry. Equisetum is sweet; bitter; flat; non-toxic; slightly cold.
- Eucommia ulmoides the dry bark of Eucommia ulmoides Oliver, is a valuable nourishing herb in China. It is listed as the top grade by the ancient Chinese medical book Shennong Bencao. It is said that it is "indications of waist and knee pain, supplementing the middle, benefiting the essence, strengthening the bones and muscles, except for the itch under the yin and urinating the rest. Long clothes, light and old.” Eucommia ulmoides is a unique Chinese medicinal material with a long history of medicinal use. Clinically, it has a wide range of applications.
- Eucommia ulmoides has liver and kidney, strong bones and muscles, removes body waste, strengthens human body cell metabolism, prevents musculoskeletal aging, balances blood pressure, decomposes body cholesterol, lowers body fat, restores blood vessel elasticity, diuretic heat, broad-spectrum antibacterial, excites central nervous system , to improve the number of white blood cells, enhance the body's immunity and other significant effects. It is used in the present invention to nourish head nutrition and promote hair regeneration.
- Bashu also known as chicken intestine, Ba Shutian, root for medicinal purposes, as a strong agent, has the effect of tonifying kidney and strengthening yang, strengthening bones and muscles, and rheumatism.
- the spatholobus (scientific name: Mi llettia dielsiana) is a plant of the genus Leguminosae, which is bitter, sweet and warm. Going to the liver, kidney, attending to promote blood circulation, nourishing blood and regulating menstruation, the main hand and foot numbness, in the medicinal value, there is the effect of Qi, Fufeng, Huoxue. Yujin, Weixin, bitter, cold.
- Chinese medicine believes that: it is blood.
- the cause of hair loss caused by traditional Chinese medicine is mostly due to weak heart and blood, lack of liver blood, resulting in blood deficiency and wind, wind and dryness can not nourish skin and hair; or liver qi stagnation, poor air, resulting in qi stagnation, hair Lost or raised; or liver and kidney yin deficiency, blood loss, dryness and loss; or overeating spicy, greasy, resulting in moisture accumulation, loss of support, hair roots are not solid; or because of excessive thinking, troubles, As a result, blood is hot and windy, and the wind is moving.
- the combination of the above compositions can enhance the conditioning effect, and with the mineral oil and various kinds of vitamin E, vitamin B1, linoleic acid, protein, sesame, polypentose, calcium, pity, iron and the like in tea seed oil
- the combination of rich nutrients further regulates the body's functions, promotes hair growth, enhances the elasticity and luster of the hair, and makes the hair loose and easy to comb.
- Clinical trial 1 :
- observation object 40 cases were selected in the Chinese Medicine Hospital of Shenzhen, Guangdong province: 20 males, 20 females; Age: 18-25 years old, 18 cases, 25-35 years old 22 cases; Occupation: 10 students, 10 workers, 5 farmers, 10 teachers, 5 other.
- Course of disease From the onset to the time of treatment, 20 cases in 2 years, 10 cases in 2-4 years, and 10 cases in 4 years.
- the effect criteria are: significant, hair loss is not obvious, giving birth to small hair more than 10%; effective, giving birth to small hair more than 5%, hair loss is controlled; invalid, hair loss is basically no improvement and reduction.
- the effect criteria are divided into: significant, hair loss is not obvious, giving birth to small hair more than 10%; effective, Hair loss of more than 5%, hair loss is controlled; invalid, hair loss is basically no improvement and relief.
- the preparation prepared by the invention can be applied to hair and scalp of various characteristics, and has no allergic reaction after washing the hair, has no toxic and side effects, and makes the drug It can quickly penetrate into the skin to achieve the purpose of hair growth, and it has quick effect, good hair growth and hair-raising effect, low cost and easy preparation process.
- the preparation of the invention is made up of tea seed oil, ginger juice, black pig bile, capillaris, earthworm, koji, safflower, smashed, orange nucleus, medlar, medlar, mulberry leaf, Equisetum, viper a paste preparation prepared from Eucommia, Eucommia, Basil, Spatholobus, and turmeric,
- the preparation method of the above-mentioned raw Chinese medicine preparation comprises the following steps:
- tea seed oil in a wok and heat it to 90-120 degrees Celsius, then put the powder of capillaris, earthworm, Kochia scoparia, safflower, smashed, orange kernel, and simmer into the pan. Deep-fried with tea seed oil, take out the oil after 15 minutes;
- the paste preparation in the above step 3) is added to the remaining hazelnut, mulberry leaf, Equisetum, Viper, Eucommia, Basil, Spatholobus, turmeric mixture, and then stirred evenly;
- the above paste preparations are stirred once a day, morning and evening, 10 minutes each time, after three days, slightly fry for half an hour, and then allowed to stand at room temperature, then add ginger juice, and stir for 10 minutes, and finally in porcelain Serve after the can.
- the prepared cream preparation is used to wipe the scalp alone or to clean the hair. If it is mixed into a common shampoo, the effect will be better.
- Example 2 The preferred raw material quality of the present invention is (g):
- the preparation method is as in Example 1.
- the mass of each component is (g):
- Tea seed oil 1400g ginger juice 160g black pig bile 40g Yinchen 30g soil glutinous rice 30g Kochia scoparia 20g ramming flower 15g bone smashing 25g orange nucleus 15g ⁇ 3 scorpion 25g mulberry 35g sage 35g snake scorpion 25g eucommia 35g ⁇ 35g spatholobus 38g turmeric 16g.
- the mass of each component is (g):
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Abstract
本发明公开了一种生发中药制剂的配方及制备方法,本发明制剂是由茶籽油、生姜汁、黑猪胆汁、茵陈、土茯苓、地肤子、闹羊花、骨碎补、橘子核、蜈蚣、榧子、桑叶、木贼草、蛇蜕、杜仲、巴戟、鸡血藤、郁金经过混合、粉粹、煎煮、搅拌等工序制备成的组合物膏状制剂,本发明可以适用于各种特点的毛发和头皮,用其清洗头发后无过敏反应,无毒副作用,使药物能迅速渗入使皮肤吸收,达到生发的目的,而且见效快,生发养发效果好,成本低廉、制取工艺简便易行。
Description
一种生发中药制剂的配方及制备方法 技术领域
本发明涉及一种生发作用的中药制剂,具体的说是涉及这种生发 作用的中药制剂及制备方法。 背景技术
在现代都市高效率、快节奏的工作生活中, 人们的脱发现象日渐 增多,也越来越严重,尤其是年轻人经常为很早就脱落的黑发所苦恼, 目前市场上治疗脱发的药物制剂不少, 但是对于西药来说, 一是价格 比较昂贵, 持续几个疗程的治疗, 给患者增加了不小的经济负担, 二 是长时间的用药容易给身体机能带来一定的副作用;对于市场上的纯 中药, 药效慢, 不稳定, 对头部毛囊的刺激作用虽然暂时有一部分毛 发生出, 如果一旦停止用药, 新生的小毛发容易脱落, 这主要和毛囊 的病变和毛发生长环境缺乏营养有关, 患者需要有一种疗效好, 使生 发持久, 并且价格相对比较低廉的药物来解决上述问题。
本发明的目的即在于针对上述不足, 在祖传秘方的基础上, 结合 现代中西医技术, 提供一种生发作用的中药制剂, 具体的说提供这种 促进生发作用的制剂及制备方法, 本发明制成的制剂, 可以适用于各 种特点的头皮, 用其清洗头发后无过敏反应, 无毒副作用, 使药物能
迅速渗入皮肤,达到生发的目的,而且成本低廉、制取工艺简便易行。 本发明的技术方案如下所述:
本发明制剂是由茶籽油、 生姜汁、 黑猪胆汁、 茵陈、 土茯苓、 地 肤子、 闹羊花、骨碎补、橘子核、蜈蚣、榧子、桑叶、木贼草、蛇蜕、 杜仲、 巴戟、 鸡血藤、 郁金制备成的组合物膏状制剂,
其中各组分的质量配比为:
茶籽油 生姜汁 黑猪胆汁 茵陈 土茯苓 地肤子
闹羊花 骨碎补 橘子核
蜈蚣 条 榧子 桑叶
木贼草 蛇蜕 杜仲
巴戟 鸡血藤 郁金
为了获得更好的效果, 本发明可优选的原料质量配比为: 茶籽油 生姜汁 黑猪胆汁 茵陈 土茯苓 地肤子
闹羊花 骨碎补 橘子核
蜈蚣 条 榧子 桑叶
木贼草 蛇蜕 杜仲
巴戟 鸡血藤 郁金
当然, 为了获得进一步好的效果, 本发明还可优选的原料质量配 茶籽油 生姜汁 黑猪胆汁
土茯苓 30g 地肤子 20g 闹羊花 15g 骨碎补 25g 橘子核 20g 蜈蚣 3条 榧子 30g 桑叶 40g 木贼草 40g 蛇蜕 30g 杜仲 40g 巴戟 40g 鸡血藤 40g 郁金 18gt 上述生发中药制剂的制备方法, 包括如下步骤:
土茯苓、 地肤子、 闹羊花、 骨碎补、 橘子核、 蜈蚣 按比例配好, 经过粉碎机粉碎并过 80目筛, 然后在 50— 70°C的高温 下烘干, 然后自然晾到室温备用;
2 )、 将茶籽油放到铁锅内加热至 90-120摄氏度, 然后将茵陈、 土茯苓、 地肤子、 闹羊花、 骨碎补、 橘子核、 蜈蚣的粉末, 下入油锅 内与茶籽油同煎, 十五分钟后取出清油备用;
3 )、 将上述清油放入陶瓷罐子内盛放, 然后加入黑猪胆汁, 一直 搅拌五分钟后, 静置经过至少一夜, 形成膏状制剂;
4)、 将榧子、 桑叶、 木贼草、 蛇蜕、 杜仲、 巴戟、 鸡血藤、 郁金 按比例配好, 经过粉碎机粉碎并过 80目筛, 然后在 50— 70°C的高温 下烘干, 然后自然晾到室温备用;
5 )、 在室温状态下, 将上述步骤 3 ) 中的膏状制剂加入剩余的榧 子、 桑叶、 木贼草、 蛇蜕、 杜仲、 巴戟、 鸡血藤、 郁金混合物, 再搅 拌均匀;
钟, 最后装于瓷罐后即成。
制取的膏状制剂单独使用擦拭头皮或清洗头发,如果将其混入到 普通的洗发液中使用, 效果会更好。 本发明的理论依据在于: 茶籽油, 又名山茶油, 野山茶油, 油茶籽油, 茶籽油是我国特有 的木本油脂,其脂肪酸组成与世界上公认的最好的植物油脂橄榄油相 似, 有 "东方橄榄油"之美称, 茶油中含有多种功能性成分, 具有明 显的预防心血管硬化、 促进新陈代谢、 降血压、 降血脂等功效, 和防 癌抗癌的特殊功效。 生姜汁, 是将姜科植物姜 Zingiber officinale Rose.洗净后打 烂, 绞取其汁入药。 其味辛, 微温。 与其他中药材配伍, 擦拭头皮或 清洗头发,可以刺激皮肤充血,改善局部血液循环,以促进毛发生长。 黑猪胆汁, 是一种很好的中药材, 中医用来治疗多种疾病, 汁中 主要成分为胆汁酸类、胆色素、粘蛋白、脂类及无机物等。味苦、寒、 咸; 可以化痰止咳平喘, 并益肺, 补脾, 润燥。 茵陈, 又名茵陈蒿, 茵陈英文名 Capi llary Wormwood Herb , 春 则因陈根而生,故名因陈或茵陈。至夏其苗则变为蒿,故亦称茵陈蒿。 味苦、辛, 微寒。 归脾、 胃、肝、胆经。茵陈清热利湿; 退黄。主治: 黄疸、小便不利、湿疮瘙痒、传染性黄疸型肝炎。药理学研究有利胆、 保护肝功能, 解热、 抗炎、 降血脂、 降压、 扩冠等作用。
土茯苓, 为百合科多年生常绿攀缘状灌木, 多生于山坡或林下, 英文名: Glabrous Greenbrier Rhizome , 性味: 甘淡, 平。 归经: 肝经; 胃经; 脾经。 功能: 解毒, 抗肿瘤, 除湿, 利关节。 主治: 治 梅毒, 淋浊, 筋骨挛痛, 脚气, 疗疔疮, 痈肿, 瘰疬, 梅毒及汞中毒 所致的肢体拘挛, 筋骨疼痛。 地肤子, 别名扫帚子、 千条子, 英文名 Fructus Kochiae, 为藜 科植物地肤 Kochia scoparia (L. ) Schrad. 的果实,性寒, 味辛、苦。 可以清热利湿, 祛风止痒。 闹羊花, 又名黄杜鹃、 黄色映山红, 隶属杜鹃花科(Ericaceae) 杜鹃花属, 为著名的有毒植物之一, 是一种常见的中草药, 在医学上 常作为麻醉、 镇痛剂使用, 可治疗风湿性关节炎、 跌打损伤。 骨碎补, 肉碎补、石岩姜、猴姜、毛姜、 申姜、爬岩姜、岩连姜, 英文名 Rhizoma Drynariae , 味苦, 温。归肾、肝经。可以补肾强骨, 续伤止痛。 用于肾虚腰痛, 耳鸣耳聋, 牙齿松动, 跌扑闪挫, 筋骨折 伤;外治斑秃、少发等,与其他药材配伍,可以有效的促进头发生长。 橘子核, 又称橘核、 橘仁、 橘米, 为植物芸香科福橘 Citrus tangerina Hort. et Tanaka或朱橘 C. erythrosa Tanaka等多禾中橘类 成熟果实的种子, 多产于福建、 浙江、 广东、 广西、 江西、 湖南、 贵 州、 云南、 四川等地, 收集食后的种子, 洗净, 晒干, 生用。 内含黄
柏内酯、 脑米林、 蛋白质及脂肪油。 味苦、 辛, 平, 归肝、 肾、 肺、 膀胱经, 可以败毒抗癌、 散结消肿, 具有显著的抗肿瘤作用。 蜈蚣, 为大蜈蚣科动物少棘巨蜈蚣或其近缘动物的干燥全虫, 是 一种常见的中药材, 具有祛风, 定惊, 攻毒, 散结作用。 可以用来治 中风, 惊痫, 破伤风, 百日咳, 风癣, 白秃, 痔漏, 烫伤等, 用于本 发明中, 具有促进生发效果。 榧子, 为红豆杉科植物榧的种子。 别名彼子、 榧实、 被子、 玉山 果、 赤果、 玉榧、 香榧、 野杉子, 位甘; 涩; 性平, 入肺、 胃、 大肠 经, 杀虫, 消积, 润燥。 桑叶, 是桑科植物量的干燥叶, 又名家桑、 荆桑、 桑椹树、 黄桑 等, 全国大部分地区多有生产, 具有降血压、 血脂、 抗炎等作用, 可 以疏散风热, 清肺润燥, 平抑肝阳, 清肝明目, 凉血止血。 我国 古代医学名录 《保生要录》 中曾有记载, 桑叶可以 "驻容颜, 乌 须发, 补髓填精, 祛疾延年" 。 木贼草, 多年生直立草本, 高 0. 5至 2米。 茎中空有节, 节间长 2至 6厘米, 表面有纵棱、 粗糙、 叶退化而抱茎, 孢子囊穗长圆形, 黄色, 轮生茎顶, 呈密穗状。 喜生于河滩, 溪边等潮湿处。 夏、 秋二 季采割, 除去杂质, 晒干或阴干。木贼草性甘; 苦; 平; 无毒; 微寒。 可以清肝明目、 止血、 利尿通淋。
蛇蜕, 英文名 PERIOSTRACUMSERPENTIS, 别名蛇皮、 蛇退、 长虫 皮、 龙衣、 蛇壳, 为游蛇科动物黑眉锦蛇 ElaphetaeniuraCopa、 锦 蛇 ElaphecarinataCGuenther )或乌梢蛇 Zaocysdhumnades ( Cantor ) 等蜕下的干燥表皮膜。 春末夏初或冬初采集, 除去泥沙, 干燥。 蛇蜕 味咸、 甘, 平。 归肝经, 可以祛风, 定惊, 解毒。 杜仲, 为杜仲禾斗植物杜仲 (Eucommia ulmoides Oliver ) 的干燥 树皮,是中国名贵滋补药材。被我国古医书《神农本草经》列为上品。 谓其 "主治腰膝痛,补中,益精气,坚筋骨,除阴下痒湿,小便余沥。 久服, 轻身耐老。 "杜仲是中国特有药材, 其药用历史悠久, 在临床 有着广泛的应用。 杜仲具有补肝肾, 强筋骨, 清除体内垃圾, 加强人 体细胞物质代谢, 防止肌肉骨骼老化, 平衡人体血压, 分解体内胆固 醇, 降低体内脂肪, 恢复血管弹性, 利尿清热, 广谱抗菌, 兴奋中枢 神经,提高白血球数量,增强人体免疫力等显著功效。用于本发明中, 可以滋补头部营养, 促进毛发再生。 巴戟, 又名鸡肠风, 巴戟天, 以根供药用, 为强壮剂, 有补肾壮 阳, 强筋骨, 祛风湿的功效。 它性微温, 味甘、 辛, 可以补肾阳, 强 筋骨, 祛风湿。 鸡血藤(学名: Mi llettia dielsiana)是豆科崖豆藤属的植物, 味苦、甘,温。归肝、 肾经, 主治活血舒筋、养血调经, 主手足麻木, 在药用价值上, 有行气、 扶风、 活血的效用。
郁金, 味辛、 苦, 性寒。 归肝、 心、 肺经, 具有行气化瘀、 清心 解郁、 利胆退黄、 活血止痛、 行气解郁、 清心凉血之用, 和本发明中 其他中药配伍, 可以促进新陈代谢, 利于头部毛囊分泌。 脱发现象, 我国中医称之为"油风"、 "蛀发癣", 属于现代医学斑 秃、 男性型脱发(脂溢性脱发)范畴等。 脱发的病因在医学上还没有 完全搞清楚, 大多认为与遗传因素、 真菌感染、 自身免疫、 内分泌功 能失调、 应激能力低下、 辐射、 慢性中毒、 微量元素缺乏、 精神过度 紧张等因素有关。 中医认为: 发为血之余。 中医对脱发的所致病因, 多认为由心血虚弱, 肝血不足, 以致血虚生风, 风胜生燥不能营养肌 肤、 毛发; 或肝气郁结, 气机不畅, 以致气滞血瘀, 发失所养而成; 或肝肾阴虚, 精血耗伤, 发枯脱落; 或过食辛辣、 油腻, 导致蕴湿积 热, 发失所养, 发根不固; 或由于思虑过度, 心绪烦扰, 以致血热生 风, 风动发落。
上述组合物的配伍组合, 可以增强调理作用, 并与茶籽油中的维 生素 E、 维生素 Bl、 亚油酸、 蛋白质、 麻糖、 多缩戊糖、 钙、 憐、 铁 等矿物质和各种丰富的营养成分相结合进一步调理人体机能,促进头 发生长, 增进头发的弹性和光泽, 使头发疏松易梳。 临床实验 1:
1 )、观察时间: 在本发明技术方案未曾披露的情况下, 选择 2013 年 1月到 2013年 7月的 6个月时间。
2 )、观察对象:在广东省深圳市中医院选择 40例病例:男 20例,
女 20例; 年龄: 16— 25岁 18例, 25— 35岁 22例; 职业: 学生 10 例, 工人 10例, 农民 5例, 教师 10例, 其他 5例。 病程: 从发病到 就诊时间, 2年内 20例, 2— 4年 10例, 4年以上 10例。
3 )、 使用方法: 将本发明制剂洗发液清洗头发, 每日 3次, 每次 饭后 1小时清洗, 1个月为 1疗程, 6个疗程作为疗效观察。
4)、 观察效果:
效果标准分为:显著,脱发不明显,生出小毛发 10%以上;有效, 生出小毛发 5%以上, 脱发得到控制; 无效, 脱发基本没有改善和减 轻。
结果 40例中, 显著 20例, 有效 13例, 无效 7例, 总有效率为 82. 5%。
临床实验 2:
1 )、观察时间: 在本发明技术方案未曾披露的情况下, 选择 2012 年 12月到 2013年 5月的 6个月时间。
2 )、观察对象:在广东省深圳市中医院选择 20例病例:男 10例, 女 10例;年龄: 16—25岁 8例, 25—35岁 12例;职业:学生 10例, 工人 2例, 农民 2例, 教师 2例, 其他 4例。 病程: 从发病到就诊时 间, 2年内 10例, 2— 4年 5例, 4年以上 5例。
3 )、 使用方法: 将本发明制剂清洗头发, 每日 3次, 每次饭前 1 小时清洗, 1个月为 1疗程, 6个疗程作为疗效观察。
4)、 观察效果:
效果标准分为:显著,脱发不明显,生出小毛发 10%以上;有效,
生出小毛发 5%以上, 脱发得到控制; 无效, 脱发基本没有改善和减 轻。
结果 20例中, 显著 14例, 有效 2例, 无效 4例, 总有效率为
80%。
结合以上临床数据及本发明的理论依据, 可见其有益效果在于, 本发明制成的制剂, 可以适用于各种特点的毛发和头皮, 用其清洗头 发后无过敏反应, 无毒副作用, 使药物能迅速渗入使皮肤吸收, 达到 生发的目的, 而且见效快, 生发养发效果好, 成本低廉、 制取工艺简 便易行。 具体实鮮式
下面结合实施例对本发明详细加以说明
实施例 1:
本发明制剂是由茶籽油、 生姜汁、 黑猪胆汁、 茵陈、 土茯苓、 地 肤子、 闹羊花、骨碎补、橘子核、蜈蚣、榧子、桑叶、木贼草、蛇蜕、 杜仲、 巴戟、 鸡血藤、 郁金制备成的组合物膏状制剂,
其中各组分的质量配比为
茶籽油 1200g 生姜汁 100g 黑猪胆汁 40g
茵陈 20g 土茯苓 20g 地肤子 20g
闹羊花 10g 骨碎补 20g 橘子核 15g
蜈蚣 3条 榧子 20g 桑叶 30g
木贼草 30g 蛇蜕 20g 杜仲 30g
巴戟 30g 鸡血藤 30g 郁金 15g。
上述生发中药制剂的制备方法, 包括如下步骤:
1 )、 将茵陈、 土茯苓、 地肤子、 闹羊花、 骨碎补、 橘子核、 蜈蚣 按比例配好, 经过粉碎机粉碎并过 80目筛, 然后在 50— 70°C的高温 下烘干, 然后自然晾到室温备用;
2 )、 将茶籽油放到铁锅内加热至 90-120摄氏度, 然后将茵陈、 土茯苓、 地肤子、 闹羊花、 骨碎补、 橘子核、 蜈蚣的粉末, 下入油锅 内与茶籽油同煎, 十五分钟后取出清油备用;
3 )、 将上述清油放入陶瓷罐子内盛放, 然后加入黑猪胆汁, 一直 搅拌五分钟后, 静置经过至少一夜, 形成膏状制剂;
4)、 将榧子、 桑叶、 木贼草、 蛇蜕、 杜仲、 巴戟、 鸡血藤、 郁金 按比例配好, 经过粉碎机粉碎并过 80目筛, 然后在 50— 70°C的高温 下烘干, 然后自然晾到室温备用;
5 )、 在室温状态下, 将上述步骤 3 ) 中的膏状制剂加入剩余的榧 子、 桑叶、 木贼草、 蛇蜕、 杜仲、 巴戟、 鸡血藤、 郁金混合物, 再搅 拌均匀;
6 )、 将上述膏状制剂每日早、 晚各搅拌一次, 每次 10分钟, 三 日后微火煎半小时, 并静置到室温, 然后加入生姜汁, 并搅拌 10分 钟, 最后装于瓷罐后即成。
制取的膏状制剂单独使用擦拭头皮或清洗头发,如果将其混入到 普通的洗发液中使用, 效果会更好。
实施例 2:
本发明还可优选的原料质量为 (克):
茶籽油 1600g 生姜汁 180g 黑猪胆汁 60g 茵陈 40g 土茯苓 40g 地肤子 30g 闹羊花 20g 骨碎补 30g 橘子核 25g 蜈蚣 3条 榧子 30g 桑叶 40g 木贼草 40g 蛇蜕 30g 杜仲 40g 巴戟 40g 鸡血藤 40g 郁金 20g。 制备方法如实施例 1。
实施例 3:
其中各组分的质量为 (克):
茶籽油 1400g 生姜汁 160g 黑猪胆汁 40g 茵陈 30g 土茯苓 30g 地肤子 20g 闹羊花 15g 骨碎补 25g 橘子核 15g 蜈蚣 3条 榧子 25g 桑叶 35g 木贼草 35g 蛇蜕 25g 杜仲 35g 巴戟 35g 鸡血藤 38g 郁金 16g。
黑猪胆汁 60g 地肤子 30g 橘子核 20g
蜈蚣 3条 榧子 30g 桑叶 40g 木贼草 40g 蛇蜕 30g 杜仲 40g
巴戟 36g 鸡血藤 36g 郁金 17g。
实施例 5:
其中各组分的质量为 (克):
茶籽油 1600g 生姜汁 180g 黑猪胆汁 60g 茵陈 30g 土茯苓 30g 地肤子 20g 闹羊花 15g 骨碎补 25g 橘子核 20g 蜈蚣 3条 榧子 30g 桑叶 40g 木贼草 40g 蛇蜕 30g 杜仲 40g 巴戟 40g 鸡血藤 40g 郁金 18g。
上述实施例仅是本发明众多实施方式的几种,如将各配方按技术方案 中的比例加大或减小药量, 制得的这种生发制剂疗效并不受影响, 也 将落在本发明的权利保护范围之内
Claims
1、 一种生发中药制剂的配方, 其特征在于, 本发明制剂是由茶 籽油、生姜汁、黑猪胆汁、茵陈、土茯苓、地肤子、 闹羊花、骨碎补、 橘子核、 蜈蚣、 榧子、 桑叶、 木贼草、 蛇蜕、 杜仲、 巴戟、 鸡血藤、 郁金制备成的组合物膏状制剂,
其中各组分的质量配比为:
茶籽油 1200-1600g 生姜汁 100-180g 黑猪胆汁 40_60g 茵陈 20-40g 土茯苓 20-40g 地肤子 20-30g 闹羊花 10- 20g 骨碎补 20-30g 橘子核 15-25g 蜈蚣 3条 榧子 20-30g 桑叶 30-40g 木贼早 30- 40g 蛇蜕 20-30g 杜仲 30-40g 巴戟 30-40g 鸡血藤 30-40g 郁金 15-20g。
2、 根据权利要求 1所述的一种生发中药制剂的配方, 其特征还 在于, 其中各组分的质量配比为:
茶籽油 1400-1600g 生姜汁 160-180g 黑猪胆汁 40_60g 茵陈 30-40g 土茯苓 30-40g 地肤子 20-30g 闹羊花 15- 20g 骨碎补 25-30g 橘子核 15-20g 蜈蚣 3条 榧子 25-30g 桑叶 35-40g 木贼早 35- 40g 蛇蜕 25-30g 杜仲 35-40g 巴戟 35-40g 鸡血藤 35-40g 郁金 15_18g。
3、 根据权利要求 1或 2所述的一种生发中药制剂的配方, 其特
茶籽油 1600g 生姜汁 180g 黑猪胆汁 60g 茵陈 30g 土茯苓 30g 地肤子 20g 闹羊花 15g 骨碎补 25g 橘子核 20g 蜈蚣 3条 榧子 30g 桑叶 40g 木贼早 40g 蛇蜕 30g 杜仲 40g 巴戟 40g 鸡血藤 40g 郁金 18g。
4、 一种生发中药制剂的制备方法, 其特征在于, 其包括如下; 土茯苓、 地肤子、 闹羊花、 骨碎补、 橘子核、 蜈蚣 按比例配好, 经过粉碎机粉碎并过 80目筛, 然后在 50— 70°C的高温 下烘干, 然后自然晾到室温备用;
2 )、 将茶籽油放到铁锅内加热至 90-120摄氏度, 然后将茵陈、 土茯苓、 地肤子、 闹羊花、 骨碎补、 橘子核、 蜈蚣的粉末, 下入油锅 内与茶籽油同煎, 十五分钟后取出清油备用;
3 )、 将上述清油放入陶瓷罐子内盛放, 然后加入黑猪胆汁, 一直 搅拌五分钟后, 静置经过至少一夜, 形成膏状制剂;
4)、 将榧子、 桑叶、 木贼草、 蛇蜕、 杜仲、 巴戟、 鸡血藤、 郁金 按比例配好, 经过粉碎机粉碎并过 80目筛, 然后在 50— 70°C的高温 下烘干, 然后自然晾到室温备用;
5 )、 在室温状态下, 将上述步骤 3 ) 中的膏状制剂加入剩余的榧 子、 桑叶、 木贼草、 蛇蜕、 杜仲、 巴戟、 鸡血藤、 郁金混合物, 再搅 拌均匀;
6 )、 将上述膏状制剂每日早、 晚各搅拌一次, 每次 10分钟, 三日后 微火煎半小时, 并静置到室温, 然后加入生姜汁, 并搅拌 10分钟, 最后装于瓷罐后即成。
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EP3434329A1 (fr) * | 2017-07-26 | 2019-01-30 | Caster | Utilisation cosmétique d'un extrait de tulipe sur les cheveux |
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CN102671095A (zh) * | 2012-05-22 | 2012-09-19 | 还童一号(福建)健康科技有限公司 | 一种健康养发、护发、黑发的纯中药组合物及其使用方法 |
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CN103054776A (zh) * | 2013-01-08 | 2013-04-24 | 李鹏 | 一种功能性中药原汁洗发液及其制备方法 |
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EP3434329A1 (fr) * | 2017-07-26 | 2019-01-30 | Caster | Utilisation cosmétique d'un extrait de tulipe sur les cheveux |
FR3069441A1 (fr) * | 2017-07-26 | 2019-02-01 | Caster | Utilisation cosmetique d'un extrait de tulipe en capillaire |
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