WO2012153253A3 - Aromatic compounds and metal complexes thereof - Google Patents
Aromatic compounds and metal complexes thereof Download PDFInfo
- Publication number
- WO2012153253A3 WO2012153253A3 PCT/IB2012/052256 IB2012052256W WO2012153253A3 WO 2012153253 A3 WO2012153253 A3 WO 2012153253A3 IB 2012052256 W IB2012052256 W IB 2012052256W WO 2012153253 A3 WO2012153253 A3 WO 2012153253A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- metal complexes
- aromatic compounds
- methods
- diagnosing
- cancer
- Prior art date
Links
- 239000002184 metal Chemical class 0.000 title abstract 3
- 150000001491 aromatic compounds Chemical class 0.000 title abstract 2
- 201000010099 disease Diseases 0.000 abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 238000003384 imaging method Methods 0.000 abstract 1
- 230000002062 proliferating effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F13/00—Compounds containing elements of Groups 7 or 17 of the Periodic Table
- C07F13/005—Compounds without a metal-carbon linkage
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
- C07F15/0006—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
- C07F15/006—Palladium compounds
- C07F15/0066—Palladium compounds without a metal-carbon linkage
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
- C07F7/1804—Compounds having Si-O-C linkages
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Provided are aromatic compounds and metal complexes thereof which may be useful treating various forms of proliferative diseases, such as cancer. In some instances, the metal complexes thereof are relatively stable, and may be suitable for oral administration. Also provided are methods of treatment, as well as methods of imaging or diagnosing a disease in a subject.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201161483593P | 2011-05-06 | 2011-05-06 | |
US61/483,593 | 2011-05-06 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2012153253A2 WO2012153253A2 (en) | 2012-11-15 |
WO2012153253A3 true WO2012153253A3 (en) | 2013-01-17 |
Family
ID=47139745
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/IB2012/052256 WO2012153253A2 (en) | 2011-05-06 | 2012-05-07 | Aromatic compounds and metal complexes thereof |
Country Status (1)
Country | Link |
---|---|
WO (1) | WO2012153253A2 (en) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103709196B (en) * | 2014-01-13 | 2016-08-17 | 武汉大学 | Coordination compound and application thereof containing PA base tetradentate ligands |
SG11201705645YA (en) | 2015-01-14 | 2017-08-30 | Bristol Myers Squibb Co | Heteroarylene-bridged benzodiazepine dimers, conjugates thereof, and methods of making and using |
CN104892494B (en) * | 2015-06-01 | 2017-08-11 | 河南师范大学 | A kind of preparation method of the ' bipyridyls of 4,4 ' dimethyl 2,2 |
CN106432070A (en) * | 2016-09-20 | 2017-02-22 | 上海应用技术大学 | Preparation method of dimethyl 6,6'-bis(bromomethyl)-[2,2'-bipyridine]-4,4'-dicarboxylate |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0283751A2 (en) * | 1987-02-25 | 1988-09-28 | AQUANAUTICS CORPORATION (a Californian corporation) | Polyalkylamine complexes for ligand extraction and generation |
-
2012
- 2012-05-07 WO PCT/IB2012/052256 patent/WO2012153253A2/en active Application Filing
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0283751A2 (en) * | 1987-02-25 | 1988-09-28 | AQUANAUTICS CORPORATION (a Californian corporation) | Polyalkylamine complexes for ligand extraction and generation |
Non-Patent Citations (1)
Title |
---|
EL-GBAYOURY ET AL.: "Convienient synthetic route to polypyridine esters by palladium-promoted carbalkoxylation", TETRAHEDRON LETTERS, vol. 39, no. 25, 1998, pages 4473 - 4476 * |
Also Published As
Publication number | Publication date |
---|---|
WO2012153253A2 (en) | 2012-11-15 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
WO2012062925A3 (en) | Compounds and methods for treating pain | |
MX349004B (en) | New compounds. | |
WO2011127333A3 (en) | Compounds for treating disease, for administering, and for pharmaceutical compositions | |
JO3776B1 (en) | PHARMACEUTICAL COMBINATIONS of a CDK4/6 inhibitor and B-Raf inhibitor | |
WO2013169704A3 (en) | TETRAHYDRONAPHTHYRIDINE AND RELATED BICYCLIC COMPOUNDS FOR INHIBITION OF RORgamma ACTIVITY AND THE TREATMENT OF DISEASE | |
WO2012083017A3 (en) | Controlled release oral dosage forms of poorly soluble drugs and uses thereof | |
WO2012048099A3 (en) | Nanoparticle-loaded cells | |
WO2014178931A8 (en) | Sobetirome in the treatment of myelination diseases | |
WO2012118812A3 (en) | Substituted 6,5-fused bicyclic heteroaryl compounds | |
PL2358697T3 (en) | Isoindoline compounds for use in the treatment of cancer. | |
AP2010005508A0 (en) | Triazole derivatives useful for the treatment of diseases. | |
MX357227B (en) | Lipid-based nanoparticles. | |
ZA201401678B (en) | Novel distributed 3,4-diamino-cyclobutene-1,2-dione compounds for use in the treatment of chemokine-mediated diseases | |
WO2013059530A3 (en) | Peptidomimetic macrocycles | |
WO2012166626A8 (en) | Reagents and methods for treating dental disease | |
WO2015191934A8 (en) | Blood-brain barrier (bbb) penetrating dual specific binding proteins for treating brain and neurological diseases | |
ZA201402907B (en) | Disubstituted 3,4-diamino-3-cyclobutene-1,2-dione compounds for use in the treatment of chemokine-mediated pathologies | |
WO2013040227A3 (en) | Therapeutic compounds | |
WO2016011049A3 (en) | Compositions and methods for disease treatment using nanoparticle delivered compounds | |
WO2013071056A3 (en) | Combination drug therapy for the treatment of solid tumors | |
WO2012106427A3 (en) | Methods for treating diabetic foot ulcers | |
EP2329007A4 (en) | Methods of enhancing the immunogenicity of mycobacteria and compositions for the treatment of cancer, tuberculosis, and fibrosing lung diseases | |
WO2015081283A3 (en) | Long non-coding rna as a diagnostic and therapeutic agent | |
HK1192726A1 (en) | 1,2,4-thiadiazol-5-ylpiperazine derivatives useful in the treatment of neurodegenerative diseases 124--5- | |
WO2012100043A3 (en) | Controlled release oral pharmaceutical dosage forms comprising mgbg |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
121 | Ep: the epo has been informed by wipo that ep was designated in this application |
Ref document number: 12782436 Country of ref document: EP Kind code of ref document: A2 |
|
NENP | Non-entry into the national phase |
Ref country code: DE |
|
122 | Ep: pct application non-entry in european phase |
Ref document number: 12782436 Country of ref document: EP Kind code of ref document: A2 |