WO2012018860A3 - Methods and devices for preparing microscopy samples - Google Patents

Methods and devices for preparing microscopy samples Download PDF

Info

Publication number
WO2012018860A3
WO2012018860A3 PCT/US2011/046328 US2011046328W WO2012018860A3 WO 2012018860 A3 WO2012018860 A3 WO 2012018860A3 US 2011046328 W US2011046328 W US 2011046328W WO 2012018860 A3 WO2012018860 A3 WO 2012018860A3
Authority
WO
WIPO (PCT)
Prior art keywords
insert
reservoir
insertion tool
methods
devices
Prior art date
Application number
PCT/US2011/046328
Other languages
French (fr)
Other versions
WO2012018860A2 (en
Inventor
Steven L. Goodman
Mark T. Nelson
Jack C. Lasee
Original Assignee
Microscopy Innovations, Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Microscopy Innovations, Llc filed Critical Microscopy Innovations, Llc
Priority to JP2013523290A priority Critical patent/JP5947794B2/en
Priority to EP11815227.1A priority patent/EP2601505B1/en
Publication of WO2012018860A2 publication Critical patent/WO2012018860A2/en
Publication of WO2012018860A3 publication Critical patent/WO2012018860A3/en

Links

Classifications

    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/24—Base structure
    • G02B21/26—Stages; Adjusting means therefor
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J37/00—Discharge tubes with provision for introducing objects or material to be exposed to the discharge, e.g. for the purpose of examination or processing thereof
    • H01J37/02—Details
    • H01J37/20—Means for supporting or positioning the object or the material; Means for adjusting diaphragms or lenses associated with the support
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N2035/1027—General features of the devices
    • G01N2035/1048—General features of the devices using the transfer device for another function
    • G01N2035/1053—General features of the devices using the transfer device for another function for separating part of the liquid, e.g. filters, extraction phase

Landscapes

  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Sampling And Sample Adjustment (AREA)

Abstract

A system for preparing and holding specimens for microscopic analysis including a capsule having an open end, an opposite end including at least one aperture and a reservoir. The system also includes an insert with a base including at least one aperture. The insert fits within and engages an inner wall of the reservoir to secure the insert within the reservoir. The system also includes an insertion tool configured to engage the insert. The insertion tool is sized to position the insert within the reservoir at a variety of positions within the reservoir. The insertion tool will disengage the insert once the insert is positioned within the reservoir. A method of positioning a specimen within a capsule for processing the specimen in preparation for microscopic analysis. A tray for holding a plurality of pipette tips in such a way that a lower end of each pipette tip is sealed.
PCT/US2011/046328 2010-08-02 2011-08-02 Methods and devices for preparing microscopy samples WO2012018860A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP2013523290A JP5947794B2 (en) 2010-08-02 2011-08-02 Method and apparatus for specimen preparation for microscope
EP11815227.1A EP2601505B1 (en) 2010-08-02 2011-08-02 A system and method for preparing and holding specimens for microscopic analysis

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US36993110P 2010-08-02 2010-08-02
US61/369,931 2010-08-02

Publications (2)

Publication Number Publication Date
WO2012018860A2 WO2012018860A2 (en) 2012-02-09
WO2012018860A3 true WO2012018860A3 (en) 2012-05-31

Family

ID=45526948

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2011/046328 WO2012018860A2 (en) 2010-08-02 2011-08-02 Methods and devices for preparing microscopy samples

Country Status (4)

Country Link
US (1) US8999273B2 (en)
EP (1) EP2601505B1 (en)
JP (1) JP5947794B2 (en)
WO (1) WO2012018860A2 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2932230B1 (en) * 2012-12-17 2020-02-05 UC-Care Ltd. Molding apparatus for embedding biological specimen in a block and related method
JP2016130673A (en) * 2015-01-14 2016-07-21 オリンパス株式会社 Sample holding container for microscopic observation
EP3290114B1 (en) * 2016-09-02 2020-02-12 Bio-Rad Europe GmbH Pipette tip container
DE102018210556A1 (en) * 2017-07-11 2019-01-17 Carl Zeiss Microscopy Gmbh Adapter for use with a sample holder and method for placing a sample in a detection beam path of a microscope
DE102019130236A1 (en) 2018-12-20 2020-06-25 Endress+Hauser Conducta Gmbh+Co. Kg Method and system for making a solution
CN115394620B (en) * 2022-10-27 2023-01-24 中铝材料应用研究院有限公司 Scanning electron microscope sample stage

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4363783A (en) * 1980-11-12 1982-12-14 C. Reichert Optische Werke, Ag Apparatus for specimen treatment
US5686313A (en) * 1992-09-08 1997-11-11 Leica Ag Method for preparation of microscopic, especially electron-microscopic, slides for the preparation of sections
US7122155B2 (en) * 2002-07-16 2006-10-17 Mcgill University Electron microscopy cell fraction sample preparation robot
US7663101B2 (en) * 2006-05-22 2010-02-16 Microscopy Innovations System and methods for preparing microscopy samples

Family Cites Families (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2783180A (en) 1954-04-14 1957-02-26 Technicon International Ltd Tissue-holder receptacles and method of preparing tissue for microscopic examination
US5139031A (en) 1989-09-18 1992-08-18 La Mina Ltd. Method and device for cytology and microbiological testing
US5080869A (en) 1990-08-14 1992-01-14 Mccormick James B Apparatus and method for preparing tissue samples for histological examination
CA2105962A1 (en) * 1992-09-18 1994-03-19 Margaret Patricia Raybuck Device and method for affinity separation
DE4333118A1 (en) 1993-09-29 1995-03-30 Leica Instr Gmbh Cassette for the treatment of samples for histological examinations, in particular for cutting preparation
DK13394A (en) 1994-01-31 1995-08-01 Peter Pavl Dudek Box with lid
US5710043A (en) * 1995-09-25 1998-01-20 Becton Dickinson And Company In vitro cell culture assembly
JP3201965B2 (en) 1995-12-28 2001-08-27 アロカ株式会社 Sample container for reagent processing and biological tissue processing device
US5817032A (en) * 1996-05-14 1998-10-06 Biopath Automation Llc. Means and method for harvesting and handling tissue samples for biopsy analysis
US6017476A (en) 1996-09-19 2000-01-25 Renshaw; Anthony A. Method for embedding and sectioning specimen
US5859699A (en) 1997-02-07 1999-01-12 Arcturus Engineering, Inc. Laser capture microdissection analysis vessel
JP3432173B2 (en) * 1999-05-12 2003-08-04 アロカ株式会社 Biological tissue processing equipment
US6395234B1 (en) 2000-02-08 2002-05-28 Triangle Biomedical Sciences, Inc. Sample cassette having utility for histological processing of tissue samples
EP1262758A1 (en) 2001-05-25 2002-12-04 Leica Mikrosysteme GmbH Container and device for tissue preparation for tissue embedding
US6458598B1 (en) 2001-08-13 2002-10-01 Dako A/S Process for preparing and presenting a tissue sample for histological study
GB0120612D0 (en) 2001-08-24 2001-10-17 Imp College Innovations Ltd Method and device
US7005110B2 (en) 2001-12-20 2006-02-28 Ventana Medical Systems, Inc. Method and apparatus for preparing tissue samples for sectioning
US7179424B2 (en) 2002-09-26 2007-02-20 Biopath Automation, L.L.C. Cassette for handling and holding tissue samples during processing, embedding and microtome procedures, and methods therefor
WO2004028693A1 (en) * 2002-09-26 2004-04-08 Biopath Automation, L.L.C. Cassette and embedding assembly, staging devices, and methods for handling tissue samples
EP1563055B1 (en) 2002-10-31 2011-07-27 University of Massachusetts Rapid cell block embedding method and apparatus
JPWO2004075740A1 (en) * 2003-02-25 2006-06-01 日本ゼオン株式会社 Tissue excision collection tool
AU2005216692B2 (en) * 2004-02-23 2010-04-22 Systagenix Wound Management Ip Co. B.V. Diagnostic swab and biopsy punch systems, and diagnostic caps for use in such systems
ATE473442T1 (en) 2004-07-23 2010-07-15 Biosystem Dev Llc DEVICE FOR AN IMMUNOASSAY AND METHOD FOR USE THEREOF
JP4153496B2 (en) * 2005-02-04 2008-09-24 セイコーインスツル株式会社 Section sample processing container, section sample processing method, and section sample processing apparatus
DK1893738T3 (en) * 2005-06-10 2019-01-28 Nunc As CULTURAL ACTION CARRIER, CULTURE ACTION AND CULTURAL ACTION SYSTEM
WO2007074769A1 (en) * 2005-12-27 2007-07-05 Kyoto University Cassette for fixing, embedding and slicing biological tissue and method of handling the same
JP3143450U (en) * 2008-05-12 2008-07-24 株式会社ファインテック Tool for preparing histopathological specimens
ES2746196T3 (en) * 2009-01-22 2020-03-05 Biopath Automation Llc Sectional microtome biopsy holder to guide tissue samples

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4363783A (en) * 1980-11-12 1982-12-14 C. Reichert Optische Werke, Ag Apparatus for specimen treatment
US5686313A (en) * 1992-09-08 1997-11-11 Leica Ag Method for preparation of microscopic, especially electron-microscopic, slides for the preparation of sections
US7122155B2 (en) * 2002-07-16 2006-10-17 Mcgill University Electron microscopy cell fraction sample preparation robot
US7663101B2 (en) * 2006-05-22 2010-02-16 Microscopy Innovations System and methods for preparing microscopy samples

Also Published As

Publication number Publication date
US8999273B2 (en) 2015-04-07
EP2601505A4 (en) 2017-12-06
EP2601505A2 (en) 2013-06-12
EP2601505B1 (en) 2019-03-27
JP2013532842A (en) 2013-08-19
JP5947794B2 (en) 2016-07-06
US20120027650A1 (en) 2012-02-02
WO2012018860A2 (en) 2012-02-09

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