WO2008038302A3 - Therapeutic formulation comprising a sulfonylurea, metformin and a nitric oxide scavenger. - Google Patents
Therapeutic formulation comprising a sulfonylurea, metformin and a nitric oxide scavenger. Download PDFInfo
- Publication number
- WO2008038302A3 WO2008038302A3 PCT/IN2007/000434 IN2007000434W WO2008038302A3 WO 2008038302 A3 WO2008038302 A3 WO 2008038302A3 IN 2007000434 W IN2007000434 W IN 2007000434W WO 2008038302 A3 WO2008038302 A3 WO 2008038302A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- metformin
- therapeutic formulation
- sulfonylurea
- nitric oxide
- oxide scavenger
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/34—Copper; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/38—Silver; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Inorganic Chemistry (AREA)
- Diabetes (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
A therapeutic formulation comprising of Sulfonylureas as active agents namely, Glibenclamide, Gliclazide, Glimepiride, Glipizide and Gliquidone, characterized in that said Sulfonylureas are combined with Metformin and combined or complexated with NO Scavenger to prevent Diabetic Complications arising out of Nitrosative stress.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IN1759/CHE/2006 | 2006-09-26 | ||
IN1759CH2006 | 2006-09-26 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2008038302A2 WO2008038302A2 (en) | 2008-04-03 |
WO2008038302A3 true WO2008038302A3 (en) | 2008-05-29 |
Family
ID=39230686
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/IN2007/000434 WO2008038302A2 (en) | 2006-09-26 | 2007-09-26 | Therapeutic formulation comprising a sulfonylurea, metformin and a nitric oxide scavenger. |
Country Status (1)
Country | Link |
---|---|
WO (1) | WO2008038302A2 (en) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2975573C (en) | 2015-02-03 | 2023-08-01 | University Court Of The University Of St Andrews | No containing compositions |
Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1997032585A1 (en) * | 1996-03-05 | 1997-09-12 | Medinox, Inc. | Combinational therapeutic methods employing nitric oxide scavengers and compositions useful therefor |
WO1998011066A1 (en) * | 1996-09-10 | 1998-03-19 | Medinox, Inc. | Polydithiocarbamate-containing macromolecules and the use thereof for therapeutic and diagnostic applications |
WO1999066924A1 (en) * | 1998-06-23 | 1999-12-29 | Medinox, Inc. | Use of nitric oxide scavengers to treat side effects caused by therapeutic administration of sources of nitric oxide |
US20020151540A1 (en) * | 2000-05-05 | 2002-10-17 | Medinox, Inc. | Therapeutic methods employing disulfide derivatives of dithiocarbamates and compositions useful therefor |
WO2005027981A1 (en) * | 2003-09-17 | 2005-03-31 | Board Of Regents, The University Of Texas System | Mechanism-based targeted pancreatic beta cell imaging and therapy |
-
2007
- 2007-09-26 WO PCT/IN2007/000434 patent/WO2008038302A2/en active Application Filing
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1997032585A1 (en) * | 1996-03-05 | 1997-09-12 | Medinox, Inc. | Combinational therapeutic methods employing nitric oxide scavengers and compositions useful therefor |
WO1998011066A1 (en) * | 1996-09-10 | 1998-03-19 | Medinox, Inc. | Polydithiocarbamate-containing macromolecules and the use thereof for therapeutic and diagnostic applications |
WO1999066924A1 (en) * | 1998-06-23 | 1999-12-29 | Medinox, Inc. | Use of nitric oxide scavengers to treat side effects caused by therapeutic administration of sources of nitric oxide |
US20020151540A1 (en) * | 2000-05-05 | 2002-10-17 | Medinox, Inc. | Therapeutic methods employing disulfide derivatives of dithiocarbamates and compositions useful therefor |
WO2005027981A1 (en) * | 2003-09-17 | 2005-03-31 | Board Of Regents, The University Of Texas System | Mechanism-based targeted pancreatic beta cell imaging and therapy |
Also Published As
Publication number | Publication date |
---|---|
WO2008038302A2 (en) | 2008-04-03 |
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