WO2006090212A3 - Method of growing bacteria to deliver bioactive compounds to the intestine of ruminants - Google Patents

Method of growing bacteria to deliver bioactive compounds to the intestine of ruminants Download PDF

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Publication number
WO2006090212A3
WO2006090212A3 PCT/IB2005/004094 IB2005004094W WO2006090212A3 WO 2006090212 A3 WO2006090212 A3 WO 2006090212A3 IB 2005004094 W IB2005004094 W IB 2005004094W WO 2006090212 A3 WO2006090212 A3 WO 2006090212A3
Authority
WO
WIPO (PCT)
Prior art keywords
rumen
ruminants
bioactive compounds
bacteria strain
intestine
Prior art date
Application number
PCT/IB2005/004094
Other languages
French (fr)
Other versions
WO2006090212A2 (en
Inventor
Lyle M Rode
James C Newbold
Original Assignee
Sage Biosciences Inc
Lyle M Rode
James C Newbold
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sage Biosciences Inc, Lyle M Rode, James C Newbold filed Critical Sage Biosciences Inc
Priority to CA002590719A priority Critical patent/CA2590719A1/en
Priority to BRPI0518845-8A priority patent/BRPI0518845A2/en
Priority to NZ555789A priority patent/NZ555789A/en
Priority to EP05857363A priority patent/EP1831349B1/en
Priority to DK05857363.5T priority patent/DK1831349T3/en
Priority to JP2007545020A priority patent/JP2008522609A/en
Priority to AT05857363T priority patent/ATE525457T1/en
Priority to AU2005328193A priority patent/AU2005328193B2/en
Publication of WO2006090212A2 publication Critical patent/WO2006090212A2/en
Publication of WO2006090212A3 publication Critical patent/WO2006090212A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/04—Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K10/00—Animal feeding-stuffs
    • A23K10/10—Animal feeding-stuffs obtained by microbiological or biochemical processes
    • A23K10/16—Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions
    • A23K10/18—Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions of live microorganisms
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/142—Amino acids; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K50/00—Feeding-stuffs specially adapted for particular animals
    • A23K50/10—Feeding-stuffs specially adapted for particular animals for ruminants
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/195—Assays involving biological materials from specific organisms or of a specific nature from bacteria
    • G01N2333/34—Assays involving biological materials from specific organisms or of a specific nature from bacteria from Corynebacterium (G)

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Polymers & Plastics (AREA)
  • Zoology (AREA)
  • Microbiology (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Food Science & Technology (AREA)
  • Animal Husbandry (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Immunology (AREA)
  • Birds (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • Physiology (AREA)
  • Biomedical Technology (AREA)
  • Toxicology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Fodder In General (AREA)
  • Feed For Specific Animals (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

Methods for increasing the resistance to rumen inactivation of a cultured Gram positive bacteria strain useful for gastrointestinal delivery of bioactive compounds to ruminants, which includes the steps of growing a culture of the bacteria strain through at least one passage in a growth medium containing an amount of lysozyme effective to induce the growth of bacterial cell walls resistant to protozoal predation; and recovering the bacteria strain from the lysozyme-containing medium. Rumen-bypass feed supplements produced by the inventive method are also disclosed, as well as methods for supplement­ing the diet of a ruminant with the rumen bypass feed supplements and an in vitro method for evaluating the resistance of Gram positive bacteria strains to rumen inactivation in vivo.
PCT/IB2005/004094 2004-12-06 2005-12-06 Method of growing bacteria to deliver bioactive compounds to the intestine of ruminants WO2006090212A2 (en)

Priority Applications (8)

Application Number Priority Date Filing Date Title
CA002590719A CA2590719A1 (en) 2004-12-06 2005-12-06 Method of growing bacteria to deliver bioactive compounds to the intestine of ruminants
BRPI0518845-8A BRPI0518845A2 (en) 2004-12-06 2005-12-06 Method for increasing resistance to ruminal inactivation of a strain of gram-positive lysine-producing bacteria, feed supplementation of protected lysine in the rumen, and methods for increasing the metabolically available lysine content of a feedstuff for ruminants, and in vitro for to evaluate the resistance of a strain of lysine-producing bacteria to in vivo rumen inactivation
NZ555789A NZ555789A (en) 2004-12-06 2005-12-06 Method of growing bacteria to deliver bioactive compounds to the intestine of ruminants
EP05857363A EP1831349B1 (en) 2004-12-06 2005-12-06 Method of growing bacteria to deliver bioactive compounds to the intestine of ruminants
DK05857363.5T DK1831349T3 (en) 2004-12-06 2005-12-06 Method of cultivating bacteria to deliver bioactive compounds to the intestine of ruminants
JP2007545020A JP2008522609A (en) 2004-12-06 2005-12-06 Bacterial culture method for supplying bioactive compounds to ruminant intestines
AT05857363T ATE525457T1 (en) 2004-12-06 2005-12-06 METHOD FOR CULTIVATION OF BACTERIA FOR DELIVERING BIOACTIVE COMPOUNDS TO THE INTESTINUM OF RUMINANTS
AU2005328193A AU2005328193B2 (en) 2004-12-06 2005-12-06 Method of growing bacteria to deliver bioactive compounds to the intestine of ruminants

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US63361104P 2004-12-06 2004-12-06
US60/633,611 2004-12-06

Publications (2)

Publication Number Publication Date
WO2006090212A2 WO2006090212A2 (en) 2006-08-31
WO2006090212A3 true WO2006090212A3 (en) 2006-11-02

Family

ID=36809505

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2005/004094 WO2006090212A2 (en) 2004-12-06 2005-12-06 Method of growing bacteria to deliver bioactive compounds to the intestine of ruminants

Country Status (12)

Country Link
US (1) US20080118472A1 (en)
EP (2) EP1831349B1 (en)
JP (1) JP2008522609A (en)
CN (1) CN101072864A (en)
AT (1) ATE525457T1 (en)
AU (1) AU2005328193B2 (en)
BR (1) BRPI0518845A2 (en)
CA (1) CA2590719A1 (en)
DK (1) DK1831349T3 (en)
NZ (1) NZ555789A (en)
RU (1) RU2416636C2 (en)
WO (1) WO2006090212A2 (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2015252095A1 (en) * 2008-12-02 2015-11-19 Dupont Nutrition Biosciences Aps Strains and methods for improving ruminant health and/or performance
WO2010065625A1 (en) 2008-12-02 2010-06-10 Danisco A/S Strains and methods for improving ruminant health and/or performance
CN107418908B (en) 2011-08-24 2021-01-08 杜邦营养生物科学有限公司 Enzyme producing bacillus strain
CN104605181A (en) * 2015-01-06 2015-05-13 铁岭新东方饲料有限公司 Environment-friendly compound feed for pig and preparation method of environment-friendly compound feed
BR102016008664A2 (en) * 2016-04-18 2018-02-20 Balieiro Neto Geraldo IGY ANTIBODY PROCESS AGAINST STREPTOCOCCUS BOVIS AND THE USE OF EVEN AS A FUNCTIONAL NATURAL FOOD ADDITIVE AS A REPLACEMENT TO THE USE OF ANTIBIOTICS IN RUMINANT DIETS
KR102265807B1 (en) * 2020-03-03 2021-06-16 나종주 Preparation method of feed additive using probiotics
CN111893070A (en) * 2020-08-12 2020-11-06 宁夏大学 Method for culturing and screening rumen bacillus licheniformis of Holstein cows
CN115956634B (en) * 2022-11-10 2023-05-12 山东健源生物科技有限公司 Biological agent for relieving heat stress of dairy cows and preparation method thereof

Citations (2)

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US5871773A (en) * 1994-02-23 1999-02-16 Ajinomoto Co., Inc. Method for supplementing amino acid levels in ruminant animals
US5928687A (en) * 1994-01-14 1999-07-27 Long Trail Enterprises, Inc. Rumen by-pass feed supplement

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US3655864A (en) 1970-09-21 1972-04-11 Smith Kline French Lab Glyceryl tristerate and higher fatty acid mixture for improving digestive absorption
US3959493A (en) * 1971-03-17 1976-05-25 Rumen Chemie, Ag Rumen bypass products comprising biologically active substances protected with aliphatic fatty acids
JPS57134500A (en) * 1981-02-12 1982-08-19 Kyowa Hakko Kogyo Co Ltd Plasmid pcg1
CA1185197A (en) * 1981-04-30 1985-04-09 Akira Furuya Lysozyme-sensitive microorganism
GB2109665B (en) * 1981-11-18 1985-07-24 Standard Telephones Cables Ltd Composite animal feed additives
JPS58126789A (en) 1981-12-29 1983-07-28 Kyowa Hakko Kogyo Co Ltd Method for developing genetic character
GB2116172B (en) * 1982-02-25 1986-07-09 Nippon Zeon Co Microbial cells containing s-adenosyl methionine in high concentrations and process for production of s adenosyl methionine
DE3311649C2 (en) * 1982-04-02 1994-08-11 Nippon Soda Co Feed additive for ruminants
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US5928687A (en) * 1994-01-14 1999-07-27 Long Trail Enterprises, Inc. Rumen by-pass feed supplement
US5871773A (en) * 1994-02-23 1999-02-16 Ajinomoto Co., Inc. Method for supplementing amino acid levels in ruminant animals

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Also Published As

Publication number Publication date
EP1831349B1 (en) 2011-09-21
JP2008522609A (en) 2008-07-03
RU2416636C2 (en) 2011-04-20
AU2005328193A1 (en) 2006-08-31
EP2311937A1 (en) 2011-04-20
CA2590719A1 (en) 2006-08-31
EP1831349A2 (en) 2007-09-12
US20080118472A1 (en) 2008-05-22
NZ555789A (en) 2009-12-24
WO2006090212A2 (en) 2006-08-31
ATE525457T1 (en) 2011-10-15
CN101072864A (en) 2007-11-14
RU2007123606A (en) 2009-01-27
AU2005328193B2 (en) 2012-03-08
BRPI0518845A2 (en) 2008-12-09
DK1831349T3 (en) 2012-01-23

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