WO2004075766A1 - Osteosynthesis plate - Google Patents

Osteosynthesis plate Download PDF

Info

Publication number
WO2004075766A1
WO2004075766A1 PCT/IB2003/003412 IB0303412W WO2004075766A1 WO 2004075766 A1 WO2004075766 A1 WO 2004075766A1 IB 0303412 W IB0303412 W IB 0303412W WO 2004075766 A1 WO2004075766 A1 WO 2004075766A1
Authority
WO
WIPO (PCT)
Prior art keywords
plate
bushings
barrels
bone
bone screws
Prior art date
Application number
PCT/IB2003/003412
Other languages
French (fr)
Inventor
Silvana Vese
Original Assignee
Silvana Vese
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Silvana Vese filed Critical Silvana Vese
Priority to US10/546,894 priority Critical patent/US20060155282A1/en
Priority to EP03816043A priority patent/EP1596740A1/en
Priority to JP2004568707A priority patent/JP2006513766A/en
Priority to AU2003249456A priority patent/AU2003249456A1/en
Priority to CA002516845A priority patent/CA2516845A1/en
Publication of WO2004075766A1 publication Critical patent/WO2004075766A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws, setting implements or the like
    • A61B17/68—Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
    • A61B17/80—Cortical plates, i.e. bone plates; Instruments for holding or positioning cortical plates, or for compressing bones attached to cortical plates
    • A61B17/8033—Cortical plates, i.e. bone plates; Instruments for holding or positioning cortical plates, or for compressing bones attached to cortical plates having indirect contact with screw heads, or having contact with screw heads maintained with the aid of additional components, e.g. nuts, wedges or head covers
    • A61B17/8047—Cortical plates, i.e. bone plates; Instruments for holding or positioning cortical plates, or for compressing bones attached to cortical plates having indirect contact with screw heads, or having contact with screw heads maintained with the aid of additional components, e.g. nuts, wedges or head covers wherein the additional element surrounds the screw head in the plate hole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws, setting implements or the like
    • A61B17/68—Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
    • A61B17/74—Devices for the head or neck or trochanter of the femur
    • A61B17/742—Devices for the head or neck or trochanter of the femur having one or more longitudinal elements oriented along or parallel to the axis of the neck
    • A61B17/746—Devices for the head or neck or trochanter of the femur having one or more longitudinal elements oriented along or parallel to the axis of the neck the longitudinal elements coupled to a plate opposite the femoral head
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws, setting implements or the like
    • A61B17/68—Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
    • A61B17/84—Fasteners therefor or fasteners being internal fixation devices
    • A61B17/86—Pins or screws or threaded wires; nuts therefor
    • A61B2017/8655—Pins or screws or threaded wires; nuts therefor with special features for locking in the bone

Definitions

  • the present invention refers to an osteosynthesis plate, such as for example a femoral plate.
  • WO97/08999 discloses a first type of plate provided with bores for the passage of bone screws in which the heads of the bone screws directly abut against the plate.
  • a second type of plate provided with barrels housing threaded pins for locking - with respect to the plate - the bone screws previously inserted into the bone is disclosed for example in EP 0649635.
  • the object of the present invention is to provide an osteosynthesis plate allowing for a reliable and permanent locking of the bone screws passing through such plate, making its manufacturing easier and less expensive, also when the shape of said plate is complex for fitting to several applications .
  • a main feature of the present invention resides in that it provides removable bushings or barrels that are threaded both on the inner and the outer surface, and provided with closing plugs for locking either the head of the bone screw or the threaded pin engaging the bone screw.
  • the osteosynthesis plate is easy to be made, has a constant thickness for its whole length, thus achieving a notable saving both of working time and of material.
  • the bores in the plate can be made inclined or tilted thus allowing an inexpensive manufacturing of particularly shaped plates.
  • Another advantage resides in that although the outer diameter of the bushings is fixed for being screwed in the bore of the plate, their inner diameters can be made different in accordance with the size of the bone screw to be fitted inside it .
  • a not last advantage of the invention is that the bone plate can be used with both bone screws directly screwed into the plate, as well as with bone screws that have been screwed to the plate in advance and are later locked through threaded pins .
  • Fig. 1 is a partially cross-sectioned elevation side view of the object osteosynthesis plate
  • Fig. 2 is a side view of a partial longitudinal cross-section of said osteosynthesis plate
  • Fig. 3 is a side view of one of said bushings to be fitted to the plate;
  • Fig. 4 is a plan bottom view of the bushing of Fig. 3.
  • a plate 1 is provided with a plurality of threaded bores 3 in which are screwed as many bushings 5 for the passage of bone screws 7; said bone screws being locked in the desired position through as many threaded plugs 9 that are screwed in the bushings 5 and lock the heads of the screws 7 in said bushings and therefore in the plate 1.
  • the bushing 5 provides for an interrupted radially protruding rim so as to form sectors 11 whereby the bushing can be turned by using a suitable tool.
  • the length of the bushing 5 is about equal to the thickness of the plate 1, nevertheless it could have a different length and extend beyond the plate 1 along the bone screw.
  • the plate 1 further includes a threaded barrel 13 that can be screwed in a bore 15 of the plate 1. Said barrel 13 allows for the passage of a bone screw 17.
  • the barrel 13 is ' provided with a slightly (frusto) conical inner bore 19 the cross-section area of which increases when going from the plate towards the outside, towards the bone, and also the (non-threaded) stem of the bone screw 17 comprises a slightly (frusto) conical portion 21 for providing a contact engagement between the two conical parts, i.e. the inner surface 19 of the bore and the stem 21 of the screw.
  • a (partially) threaded pin or bolt 23 engages an axial bore 25 drilled in the head of the bone screw 17 for strengthening the contact engagement between the conical surfaces 19 and 21 when said screw 17 is turned to be pulled towards the plate 1 when screwing the bolt 23.
  • the hollow 29 housing the head 27 of said bolt 23 is closed by a threaded plug 31.
  • the threaded plug 31 allows for locking the bolt 23 and it is similar to the threaded plugs 9 that are screwed in the bushings 5 for locking the screw heads in the plate 1.

Landscapes

  • Health & Medical Sciences (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Surgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Surgical Instruments (AREA)
  • Orthopedics, Nursing, And Contraception (AREA)

Abstract

An osteosynthesis plate (1) is provided with a plurality of threaded bores (3) in which bushings or barrels (5;13) for the passage of bone screws (7) are screwed; said bone screws (7) being locked in position through threaded plugs (9) that are screwed in the bushings (5) and prevent the unscrewing of said bone screws.

Description

"OSTEOSYNTHESIS PLATE"
The present invention refers to an osteosynthesis plate, such as for example a femoral plate.
As it is currently known for the repair of bone fractures, particularly femur fractures, there are used suitably-shaped one-piece plates, provided with a plurality of holes or bores to allow the passage of screw to be inserted into the bone. There are known various types of plates and fastening screws arrangements .
For example WO97/08999 discloses a first type of plate provided with bores for the passage of bone screws in which the heads of the bone screws directly abut against the plate. A second type of plate provided with barrels housing threaded pins for locking - with respect to the plate - the bone screws previously inserted into the bone is disclosed for example in EP 0649635.
One of the problems encountered when using plates of the above discussed type is the difficulty to firmly secure the bone screw with the plate, once said screw has been fastened in the bone .
A solution to the above problem has been proposed in WO01/91660 that teaches the use of internally hollow bushings screwed in the threaded bores provided in the plate. According to the teaching of this document, there are provided locking bushings with a conical bore the surface of which co-operates with the conical surface of the bone screw passing through the bushing. Alternatively there are provided bushings that are rendered deformable thanks to radial cuts that block the head of the bone screw.
The object of the present invention is to provide an osteosynthesis plate allowing for a reliable and permanent locking of the bone screws passing through such plate, making its manufacturing easier and less expensive, also when the shape of said plate is complex for fitting to several applications .
This and other objects are accomplished through an osteosynthesis plate as claimed in the appended claims.
A main feature of the present invention resides in that it provides removable bushings or barrels that are threaded both on the inner and the outer surface, and provided with closing plugs for locking either the head of the bone screw or the threaded pin engaging the bone screw.
In such a way, the osteosynthesis plate is easy to be made, has a constant thickness for its whole length, thus achieving a notable saving both of working time and of material.
Besides, according to the invention, the bores in the plate can be made inclined or tilted thus allowing an inexpensive manufacturing of particularly shaped plates.
Another advantage resides in that that although the outer diameter of the bushings is fixed for being screwed in the bore of the plate, their inner diameters can be made different in accordance with the size of the bone screw to be fitted inside it .
A not last advantage of the invention is that the bone plate can be used with both bone screws directly screwed into the plate, as well as with bone screws that have been screwed to the plate in advance and are later locked through threaded pins .
The invention will now be disclosed in detail with particular reference to the attached drawings referring to a non limiting embodiment thereof, in which:
Fig. 1 is a partially cross-sectioned elevation side view of the object osteosynthesis plate;
Fig. 2 is a side view of a partial longitudinal cross-section of said osteosynthesis plate;
Fig. 3 is a side view of one of said bushings to be fitted to the plate;
Fig. 4 is a plan bottom view of the bushing of Fig. 3.
As clearly shown in the figures, a plate 1 is provided with a plurality of threaded bores 3 in which are screwed as many bushings 5 for the passage of bone screws 7; said bone screws being locked in the desired position through as many threaded plugs 9 that are screwed in the bushings 5 and lock the heads of the screws 7 in said bushings and therefore in the plate 1.
Advantageously, the bushing 5 provides for an interrupted radially protruding rim so as to form sectors 11 whereby the bushing can be turned by using a suitable tool.
Preferably the length of the bushing 5 is about equal to the thickness of the plate 1, nevertheless it could have a different length and extend beyond the plate 1 along the bone screw.
The plate 1 further includes a threaded barrel 13 that can be screwed in a bore 15 of the plate 1. Said barrel 13 allows for the passage of a bone screw 17.
According to the invention, the barrel 13 is ' provided with a slightly (frusto) conical inner bore 19 the cross-section area of which increases when going from the plate towards the outside, towards the bone, and also the (non-threaded) stem of the bone screw 17 comprises a slightly (frusto) conical portion 21 for providing a contact engagement between the two conical parts, i.e. the inner surface 19 of the bore and the stem 21 of the screw.
A (partially) threaded pin or bolt 23 engages an axial bore 25 drilled in the head of the bone screw 17 for strengthening the contact engagement between the conical surfaces 19 and 21 when said screw 17 is turned to be pulled towards the plate 1 when screwing the bolt 23. Also the hollow 29 housing the head 27 of said bolt 23 is closed by a threaded plug 31. The threaded plug 31 allows for locking the bolt 23 and it is similar to the threaded plugs 9 that are screwed in the bushings 5 for locking the screw heads in the plate 1.

Claims

1. An osteosynthesis plate (1) provided of a plurality of threaded bores (3; 15) in which as many bushings or barrels (5;13) are screwed for the passage of bone screws (7;17); said bone screws being locked in position through as many threaded plugs (9; 31) that are screwed in said bushings or barrels (5;13) and block said bone screws (7;17) in said plate (1).
2. A plate as claimed in claim 1, in which said plugs (9; 31) lock in said bushings (5) the heads of said bone screws (7;17) .
3. A plate as claimed in claim 1, in which said plugs (9; 31) lock in said bushings or barrels (5; 13) the heads of corresponding threaded pins or bolts (23) engaging threaded bores (25) provided in the head of said bone screws (7;17).
4. A plate as claimed in claim 2, in which said bushings or barrels (5; 13) are provided with a (frusto) conical inner surface, the cross-section area of which increases from the plate towards the outside, towards the bone, said inner
(frusto) conical surface co-operating with a complementary (frusto) conical outer surface of the bone screw to allow the locking of said screw in said barrel thanks to the Cupertino between said conical surfaces.
5. A plate as claimed in claim 1, >in which said bushings or barrels (5; 13) comprise interrupted radially protruding rims so as to form sectors (11) whereby said bushing can be turned by using a suitable tool.
6. A plate as claimed in claim 1, in which the length of said bushings or barrels (5; 13) is approximately equal to the thickness of said plate (1) .
7. A plate as claimed in claim 1, in which said bushings or barrels (5; 13) have a length greater than the thickness of the plate (1) and extend for part of the length of the bone screw that is fitted in said bushings or barrels (5; 13).
8. A plate as claimed in claim 1, in which said plate is a femoral plate.
9. A plate as claimed in claim 1, in which said threaded bores (3; 15) are inclined with respect to the plane of said plate.
PCT/IB2003/003412 2003-02-28 2003-07-31 Osteosynthesis plate WO2004075766A1 (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
US10/546,894 US20060155282A1 (en) 2003-02-28 2003-07-31 Osteosynthesis plate
EP03816043A EP1596740A1 (en) 2003-02-28 2003-07-31 Osteosynthesis plate
JP2004568707A JP2006513766A (en) 2003-02-28 2003-07-31 Osteosynthesis plate
AU2003249456A AU2003249456A1 (en) 2003-02-28 2003-07-31 Osteosynthesis plate
CA002516845A CA2516845A1 (en) 2003-02-28 2003-07-31 Osteosynthesis plate

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ITTO2003U000034 2003-02-28
IT000034U ITTO20030034U1 (en) 2003-02-28 2003-02-28 PLATE OF OSTEOSYNTHESIS

Publications (1)

Publication Number Publication Date
WO2004075766A1 true WO2004075766A1 (en) 2004-09-10

Family

ID=32923048

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2003/003412 WO2004075766A1 (en) 2003-02-28 2003-07-31 Osteosynthesis plate

Country Status (8)

Country Link
US (1) US20060155282A1 (en)
EP (1) EP1596740A1 (en)
JP (1) JP2006513766A (en)
CN (1) CN1744860A (en)
AU (1) AU2003249456A1 (en)
CA (1) CA2516845A1 (en)
IT (1) ITTO20030034U1 (en)
WO (1) WO2004075766A1 (en)

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006087159A1 (en) 2005-02-19 2006-08-24 Aesculap Ag & Co. Kg Orthopedic fixation system
WO2006124987A1 (en) * 2005-05-17 2006-11-23 Smith & Nephew, Inc. Axial compression fastener system
WO2009043827A1 (en) * 2007-09-26 2009-04-09 Zimmer Gmbh Bone anchoring device for the operative repair of fractures
EP2092904A1 (en) * 2008-02-22 2009-08-26 Prévôt, Bertrand Trochanter plate
WO2009120142A1 (en) * 2008-03-27 2009-10-01 Swemac Innovation Ab Device for fixation of bone fragments at bone fractures
US7670341B2 (en) 2005-12-16 2010-03-02 Depuy Products, Inc. Orthopaedic device with locking barrel
EP2185092A1 (en) * 2007-07-24 2010-05-19 Henrik Hansson Device for fixation of bone fragments at bone fractures
WO2010103494A2 (en) * 2009-03-12 2010-09-16 Intrauma S.R.L. Osteosynthesis plate for femur fractures
WO2018095830A1 (en) * 2016-11-24 2018-05-31 Vetsos Ltd Orthopaedic apparatus

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2300967T3 (en) * 2005-03-11 2008-06-16 Orthofix S.R.L. DEVICE FOR OSTEOSYNTHESIS OF PROXIMAL FRACTURES OF THE HUMER.
WO2007118317A1 (en) * 2006-04-13 2007-10-25 Arno Smit Hip protector implant
JP5158860B2 (en) * 2008-03-05 2013-03-06 ナカシマプロペラ株式会社 Implant for femoral fracture treatment
KR101106466B1 (en) * 2009-04-27 2012-01-20 케이시시정공 주식회사 Normal Open Solenoid Valve
US8790379B2 (en) 2010-06-23 2014-07-29 Zimmer, Inc. Flexible plate fixation of bone fractures
WO2011163387A2 (en) * 2010-06-23 2011-12-29 Apex Biomedical Company, Llc Flexible plate fixation of bone fractures
US10111696B2 (en) 2011-08-25 2018-10-30 DePuy Synthes Products, Inc. Implant
US9662156B2 (en) 2011-11-18 2017-05-30 DePuy Synthes Products, Inc. Femoral neck fracture implant
US9295508B2 (en) 2012-02-03 2016-03-29 Zimmer, Inc. Bone plate for elastic osteosynthesis
US9398928B2 (en) * 2012-09-28 2016-07-26 DePuy Synthes Products, Inc. Adjustable height arthroplasty plate
CN103445848B (en) * 2013-07-03 2015-10-14 厦门大博颖精医疗器械有限公司 Children's's osteotomy lockplate
CN107789044A (en) * 2016-09-05 2018-03-13 财团法人金属工业研究发展中心 Bone is broken fixing device
US11324538B2 (en) 2019-12-04 2022-05-10 Biomet Manufacturing, Llc Active bone plate
CN115120323A (en) * 2021-03-26 2022-09-30 健宝生技股份有限公司 Bone locking system and method

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FR782462A (en) * 1934-02-26 1935-06-05 Simal Et A Legros D Instrumentation device for osteo-synthesis with external support
US4628923A (en) * 1983-11-28 1986-12-16 Medoff Robert J Axial compression device
US5591168A (en) * 1993-10-25 1997-01-07 Tornier S.A. Device for stabilizing fractures of the upper end of the femur
WO1997008999A1 (en) * 1995-09-08 1997-03-13 Depuy Ace Medical Company Internal bone fracture fixator
US6102952A (en) * 1995-04-07 2000-08-15 Koshino; Tomihisa Medical substituting element for hard tissues and artificial joint
WO2001091660A1 (en) 2000-05-31 2001-12-06 Vese, Silvana Device for fixing a bone plate

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US5514138A (en) * 1991-02-08 1996-05-07 Pfizer Inc. Connector having a stop member
IL105183A (en) * 1993-03-28 1996-07-23 Yehiel Gotfried Surgical device for connection of fractured bones
US5976139A (en) * 1996-07-17 1999-11-02 Bramlet; Dale G. Surgical fastener assembly
US6235033B1 (en) * 2000-04-19 2001-05-22 Synthes (Usa) Bone fixation assembly

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR782462A (en) * 1934-02-26 1935-06-05 Simal Et A Legros D Instrumentation device for osteo-synthesis with external support
US4628923A (en) * 1983-11-28 1986-12-16 Medoff Robert J Axial compression device
US5591168A (en) * 1993-10-25 1997-01-07 Tornier S.A. Device for stabilizing fractures of the upper end of the femur
US6102952A (en) * 1995-04-07 2000-08-15 Koshino; Tomihisa Medical substituting element for hard tissues and artificial joint
WO1997008999A1 (en) * 1995-09-08 1997-03-13 Depuy Ace Medical Company Internal bone fracture fixator
WO2001091660A1 (en) 2000-05-31 2001-12-06 Vese, Silvana Device for fixing a bone plate

Cited By (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006087159A1 (en) 2005-02-19 2006-08-24 Aesculap Ag & Co. Kg Orthopedic fixation system
JP2008529694A (en) * 2005-02-19 2008-08-07 アエスキュラップ アーゲー Orthopedic fixation system
JP4685114B2 (en) * 2005-02-19 2011-05-18 アエスキュラップ アーゲー Orthopedic fixation system
WO2006124987A1 (en) * 2005-05-17 2006-11-23 Smith & Nephew, Inc. Axial compression fastener system
US7670341B2 (en) 2005-12-16 2010-03-02 Depuy Products, Inc. Orthopaedic device with locking barrel
US9308032B2 (en) 2007-07-24 2016-04-12 Henrik Hansson Device for fixation of bone fragments at bone fractures
EP2185092A1 (en) * 2007-07-24 2010-05-19 Henrik Hansson Device for fixation of bone fragments at bone fractures
EP2185092A4 (en) * 2007-07-24 2013-05-15 Henrik Hansson Device for fixation of bone fragments at bone fractures
EP2190369B1 (en) 2007-09-26 2016-07-20 Zimmer GmbH Bone anchoring device for the operative repair of fractures
US8641740B2 (en) 2007-09-26 2014-02-04 Zimmer, Gmbh Bone anchoring device for the operative repair of fractures
AU2008306998B2 (en) * 2007-09-26 2014-04-10 Markus Kuster Bone anchoring device for the operative repair of fractures
WO2009043827A1 (en) * 2007-09-26 2009-04-09 Zimmer Gmbh Bone anchoring device for the operative repair of fractures
CN101902977B (en) * 2007-09-26 2012-06-13 捷迈有限责任公司 Bone anchoring device for the operative repair of fractures
EP2092904A1 (en) * 2008-02-22 2009-08-26 Prévôt, Bertrand Trochanter plate
WO2009120142A1 (en) * 2008-03-27 2009-10-01 Swemac Innovation Ab Device for fixation of bone fragments at bone fractures
EP2271274A1 (en) * 2008-03-27 2011-01-12 Swemac Innovation Ab Device for fixation of bone fragments at bone fractures
EP2271274A4 (en) * 2008-03-27 2015-04-01 Swemac Innovation Ab Device for fixation of bone fragments at bone fractures
US9101420B2 (en) 2008-03-27 2015-08-11 Swemac Innovation Ab Device for fixation of bone fragments at bone fractures
WO2010103494A3 (en) * 2009-03-12 2010-12-29 Intrauma S.R.L. Osteosynthesis plate for femur fractures
WO2010103494A2 (en) * 2009-03-12 2010-09-16 Intrauma S.R.L. Osteosynthesis plate for femur fractures
WO2018095830A1 (en) * 2016-11-24 2018-05-31 Vetsos Ltd Orthopaedic apparatus
US11357553B2 (en) 2016-11-24 2022-06-14 VetSOS Ltd. Orthopaedic apparatus

Also Published As

Publication number Publication date
AU2003249456A1 (en) 2004-09-17
ITTO20030034U1 (en) 2004-09-01
EP1596740A1 (en) 2005-11-23
JP2006513766A (en) 2006-04-27
CA2516845A1 (en) 2004-09-10
CN1744860A (en) 2006-03-08
US20060155282A1 (en) 2006-07-13

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