WO2002034315A1 - A medication delivery device with telescopic piston rod - Google Patents
A medication delivery device with telescopic piston rod Download PDFInfo
- Publication number
- WO2002034315A1 WO2002034315A1 PCT/DK2001/000697 DK0100697W WO0234315A1 WO 2002034315 A1 WO2002034315 A1 WO 2002034315A1 DK 0100697 W DK0100697 W DK 0100697W WO 0234315 A1 WO0234315 A1 WO 0234315A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- piston rod
- telescopic piston
- telescopic
- cartridge
- delivery device
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/145—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
- A61M5/1452—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons
- A61M5/14566—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons with a replaceable reservoir for receiving a piston rod of the pump
Definitions
- the invention relates to a medication delivery device for delivering medicine or other fluent material into a mammal body.
- Medication delivery devices are widely used in the health sector for delivering fluent medicine into mammal bodies through a conduit inserted in the body.
- the first type being an injection device, which injects a selected dose of fluent medicine into a mammal body whenever the injection device is activated.
- the other type being an infusion device, which delivers a constant rate of medicine into a mam- al body either by gravity or by pressure, which pressure are usually generated by an electrical motor.
- a medication delivery device for injecting pte-selected doses of fluent medicine into the body is known from WO 90.09202.
- the medication delivery device shown in this publication comprises a piston rod made up from an outer part and an inner part.
- the inner part has an exterior thread and is rotated by a drive mechanism.
- the outer part has an interior thread mating the thread of the inner part and is locked against rotation, such that the outer part moves forward whenever the inner part is being rotated. Since the outer part at its distal end abuts the elastomeric piston of the cartridge, this elastomeric piston is moved forward when the inner part is rotated hence expelling an amount of the medicine contained in the cartridge.
- the length of the outer part of the piston rod has to be at least equal to the length of the cartridge.
- the total length of the injection device must therefore be at least twice the length of the cartridge.
- a telescopic piston rod In order to produce medication delivery devices shorter than twice the length of the cartridge, a telescopic piston rod has been developed.
- a telescopic piston rod is shown, utilized in an infusion device, in WO 97.00091 ,
- This known piston rod comprises of a plurality of pieces or parts, which are connected to each other by mating threads.
- the distal part of the telescopic piston rod is connected to the elastomeric piston of the cartridge, and is prevented form rotating by a number of bushings surrounding the telescopic piston rod and being stiffly connected to the housing of the medication delivery device.
- the drive rotates the proximal part of the telescopic piston rod, the distal part moves forward hence expelling the medicine contained in the cartridge.
- the bushing having the smallest diameter must surround the part of the telescopic piston rod having the largest diameter, as shown in WO 97.00091.
- the bushing having the smallest diameter then has to fit into at least one other bushing having a greater diameter, and finally the interior diameter of the cartridge has to be larger than the diameter of the largest bushing.
- the diameter of the cartridge must be of a considerable size, especially if a long cartridge having a telescopic piston rod made up from a large number of parts is called for.
- a medication delivery device for delivering medicine or other fluent material to a mammal body having a housing accommodating a cartridge containing an amount of said medicine, comprising:
- an elastomeric piston movable mounted in said cartridge which elastomeric piston is moved from a proximal end of said cartridge to a distal end of said cartridge by rotating at least a part of a first telescopic piston rod, which first telescopic piston rod has a distal part abutting said elastomeric piston and a proximal part rotatably mounted in said housing and a plurality of parts there between, said parts being connected to each other by mating threads, drive means for rotating said first telescopic piston rod, such that said elastomeric piston moves forward inside said cartridge and expels an amount of said medicine, and
- said means preventing said elastomeric piston from rotating when at least a part of said first telescopic piston rod is rotated comprises an additional telescopic piston rod having a proximal end mounted in said housing and a distal end abutting said elastomeric piston.
- both piston rods can be made with a very little diameter, such that they both at the same time can fit into the interior of a standard cartridge. Since they are both fitted into the same cartridge, the addition of the diameter of both the telescopic piston rods is substantially smaller than the interior diameter of the cartridge, thereby leaving some non-occupied space both in the cartridge and in the housing of the medication delivery device.
- 'piston rod' is in the present context taken to be the element which are used to ap- ply pressure to a surface of the elastomeric piston, such that the elastomeric piston is being displaced and the contents of the cartridge is being expelled,
- the term 'telescopic piston rod' is taken to mean a piston rod made up from a number of individual parts or pieces, which parts or pieces preferably has a circular cross-section, but the parts could if wanted be of any desired form. All the pieces, although the most distal part or piece could be solid is preferably hollow thereby creating an interior compartment in each part or piece, which compartment has a diameter or a width large enough to fit the neighbouring piece into the compartment such that the telescopic piston rod can be transformed from a position where all the pieces are contained in the compartment of the neighbouring piece to a position where all the pieces are extracted out of the compartments or almost of the compartments In the first position the overall length of the telescopic piston rod is somewhat equal to the length of the longest part or piece, and in the extracted position the length of the telescopic piston rod almost equals the total sum of the length of each individual piece
- the first telescopic piston rod and said additional telescopic piston rod is connected to each other through a synchronisation gear such that both telescopic pistons rods rotates with the same rotational speed, and that one of said telescopic piston rods is rotated by an electrical motor which drives one of said telescopic piston rod through a driving gear, it is ensured that although the electrical motor only drives one of the two telescopic piston rods they are both rotated with the same rotational speed If the pitch of the threads connecting the pieces of each telescopic piston rod is the same for both telescopic piston rods it is ensured that the distal end of each telescopic piston rod moves at the same speed If the synchronization utilizes only two gear wheels, as shown, the first tele- scopic piston rod and the additional telescopic piston rod will rotate in different directions When the two telescopic piston rods are moving in different directions, the momentum deliv ⁇ ered to the elastomeric piston from the one telescopic piston
- the first telescopic piston rod and said additional telescopic piston rod each comprises of three parts, a first part having an interior thread, a third part having an exterior thread and an intermediate second part having an exterior thread mating said interior thread of said first part and an interior thread mating said exterior thread of said third part Having a telescopic piston rod made up from three parts have been found to provide a length and a stability suitable for a medication delivery device
- the first part of said first telescopic piston rod and said first part of said additional telescopic piston rod is located at said proximal end of said cartridge, and that said third part of said first telescopic piston rod and said third part of said additional telescopic piston rod is moving towards said distal end of said cartridge, it is ensured that the piece of each telescopic piston rod having the largest diameter and containing the other pieces of the telescopic piston rod is the piece located at the most proximal end of the medication delivery device
- the direction of the pith of the threads provided on the pieces making up each telescopic piston rod determines in which direction each telescopic piston rod moves when the first piece is being rotated
- the direction of said threads of said first telescopic piston rod and said additional tele- scopic piston rod is such that said distal end of each telescopic piston rod travels in the same direction inside said cartridge when one of said telescopic piston rods is rotated
- the first telescopic piston rod at said distal end is connected to said distal end of said additional telescopic piston rod preferably through a circular plate abutting said elastomeric piston inside said cartridge, it is ensured that the two telescopic piston rods are locked to each other and that the momentum is adequate balanced between the two telescopic piston rods
- Figure 1 Shows a perspective view of the medication delivery device according to the invention
- Figure 3 Shows a sectional view along line A-A in figure 2
- Figure 4 Shows a cross-sectional view of the prior art medication delivery device
- Figure 5 Shows a cross-sectional iew of the medication delivery device according to the present invention
- FIG. 1 to 3 shows a medical injection device comprising a housing 1 accommodating a cartridge 2 containing the fluent medicine to be injected An elastomeric piston 3 is movable mounted inside the cartridge 2 The fluent medicine will be expelled when the movable elas- tomenc piston 3 is moved towards the distal end of the medical injection device
- the elastomeric piston 3 is moved forward by a first telescopic piston rod 4 made up from three parts 5, 6 7
- the first part 5 has an interior thread mating the exterior thread of the second intermediate part 6
- the second intermediate part 6 is in addition provided with an interior thread mating the exterior thread of the third part 7
- the second intermediate part 6 and the third part 7 will be moved in the distal direction due to the mating threads This will cause the elastomeric piston 3 to move in the distal direction and expel the medicine contained in the cartridge 2
- Rotating the first part 5 of the first telescopic piston rod 4 is done by an electrical motor 8 which is coupled to the first part 5 of the first telescopic piston rod 4 through a number of gearing wheels 9, 10, 1 1
- the first part 5 of the telescopic piston rod is rotatably mounted in the housing 1 through a number of ball bearings 12 Other types of bearings can off cause be used if so wanted
- Locking the elastomeric piston 3 and the first part 5 of the telescopic piston rod 4 against rotation can be done in many different ways
- the locking is realized by providing an additional telescopic piston rod 14
- This additional telescopic piston rod 14 is made up in the same manner as the first telescopic piston rod 4 and comprises three parts 15, 16, 17, which is connected together by mating threads
- the third part 17 of the additional telescopic piston rod 14 is at the distal end connected to the first telescopic piston rod 4 through a circular plate 18 having a distal side abutting the elastomenc piston 3, and the first part 15 of the additional telescopic piston rod 14 is rotatably mounted in the housing 1 by a number of ball bear ⁇ ngs19
- the additional telescopic piston rod 14, which sole purpose is to prevent the elastomeric piston 3 and the third part 7 of the first telescopic piston rod 4 from rotating when the first part 5 of the first telescopic piston rod 4 is rotated, can either be made as a dummy slave following the longitudinal movement of the first telescopic piston rod 4, or it can be fully synchronized with the first telescopic piston rod 4
- the additional telescopic piston rod 14 When the additional telescopic piston rod 14 is made as a dummy slave it is preferably made without any threads and connected to the first telescopic piston rod only through the circular plate 18, or by other means only transmitting the longitudinal movement from the first telescopic piston rod 4 to the additional telescopic piston rod 14 Since only longitudinal movement is transmitted, the first part 15 of the additional telescopic piston 14 rod need not be rotational mounted in the housing 1
- the synchronisation can be done by providing the first telescopic piston rod 4 and the additional telescopic piston rod 14 with a synchronization gear made up from a first gear wheel 20 connected to the first telescopic piston rod 4 and a second gear wheel 21 con- nected to the additional telescopic piston rod 14, which two gear wheels 20,21 interconnects with each other
- the first telescopic piston rod 4 and the additional piston rod 14 will rotate in different directions, which will cause the momentum delivered from the first telescopic piston rod 4 to be equalized by the momentum delivered from the additional telescopic piston rod 14, such that the resulting momentum working on the circular plate 18 will be zero
- the mating threads connecting the three parts 5, 6, 7 of the first telescopic piston rod 4 and the mating threads connecting the three parts 15, 16, 7 of the additional telescopic piston rod 14 has to be in a direction which will cause the distal end of both the first telescopic piston rod 4 and the distal end of the additional telescopic piston rod 14 to move in the distal direction inside the cartridge when the first part 5 of the first telescopic piston rod 4 is rotated
- Figure 4 shows a cross-sectional view of the prior art medication delivery device shown in figure 3B in WO 97 00091
- the outside diameter of the outer bushing 23 is somewhat equal to the interior diameter of the cartridge 24
- the outside diameter of the outer bushing protrudes into the housingl of the medication delivery device, leaving no space for the remaining parts of the medication delivery device
- Figure 5 shows a cross-sectional view of the medication delivery device of the present invention Since both telescopic piston rods 4J4 are fitted into the same cartridge 2, the largest outside diameter of each telescopic piston rod 4,14 has to be substantially smaller than the interior diameter of the cartridge 2 Since the largest outside diameter of each telescopic piston rod 4,14 protrudes into the housing 1 a large amount of non-occupied space is available inside the housing 1 in comparison with the prior art medication delivery device
Landscapes
- Health & Medical Sciences (AREA)
- Vascular Medicine (AREA)
- Engineering & Computer Science (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
Abstract
A medication delivery device comprising a container containing a fluid medicament. The medicament is expelled from the container by moving forward an elastomeric piston inside the cartridge. The piston is moved forward by a telescopic piston rod, which can either be centrally located in the container or eccentric located. One end of the telescopic piston rod abuts the elastomeric piston either by itself or through an additional plate. The abutment having a friction large enough to prevent a lower part of the telescopic rod from rotating. In order to prevent the elastomeric piston from rotating inside the container a second telescopic piston rod is provided parallel with the first telescopic piston rod.
Description
A medication delivery device with telescopic piston rod
The Technical field of the invention:
The invention relates to a medication delivery device for delivering medicine or other fluent material into a mammal body.
Description of related art: Medication delivery devices are widely used in the health sector for delivering fluent medicine into mammal bodies through a conduit inserted in the body. In general two types of medication delivery devices exist. The first type being an injection device, which injects a selected dose of fluent medicine into a mammal body whenever the injection device is activated. The other type being an infusion device, which delivers a constant rate of medicine into a mam- al body either by gravity or by pressure, which pressure are usually generated by an electrical motor.
People suffering from diabetes will require insulin to be delivered into the body either through several injections every day or through a constant infusion,
A medication delivery device for injecting pte-selected doses of fluent medicine into the body is known from WO 90.09202. The medication delivery device shown in this publication comprises a piston rod made up from an outer part and an inner part. The inner part has an exterior thread and is rotated by a drive mechanism. The outer part has an interior thread mating the thread of the inner part and is locked against rotation, such that the outer part moves forward whenever the inner part is being rotated. Since the outer part at its distal end abuts the elastomeric piston of the cartridge, this elastomeric piston is moved forward when the inner part is rotated hence expelling an amount of the medicine contained in the cartridge. In order to fully empty a cartridge the length of the outer part of the piston rod has to be at least equal to the length of the cartridge. The total length of the injection device must therefore be at least twice the length of the cartridge.
In order to produce medication delivery devices shorter than twice the length of the cartridge, a telescopic piston rod has been developed. Such a telescopic piston rod is shown, utilized in an infusion device, in WO 97.00091 , This known piston rod comprises of a plurality of pieces
or parts, which are connected to each other by mating threads. The distal part of the telescopic piston rod is connected to the elastomeric piston of the cartridge, and is prevented form rotating by a number of bushings surrounding the telescopic piston rod and being stiffly connected to the housing of the medication delivery device. When the drive rotates the proximal part of the telescopic piston rod, the distal part moves forward hence expelling the medicine contained in the cartridge.
Disclosure of the invention:
If the shown telescopic piston rod has to fold and unfold correctly the bushing having the smallest diameter must surround the part of the telescopic piston rod having the largest diameter, as shown in WO 97.00091. The bushing having the smallest diameter then has to fit into at least one other bushing having a greater diameter, and finally the interior diameter of the cartridge has to be larger than the diameter of the largest bushing. As a result of this the diameter of the cartridge must be of a considerable size, especially if a long cartridge having a telescopic piston rod made up from a large number of parts is called for.
Another deficiency of the prior art medication delivery device is that the part of the largest bushing protruding out from the cartridge has to have an overall diameter equaling the interior diameter of the cartridge, leaving only a limited space in the housing for the remaining parts of the medication delivery device.
It is an object of the present invention to provide a medication delivery device, which does not posses the drawbacks of the prior art medication delivery devices, where the diameter of the cartridge is minimized, and where the non-occupied space available inside the housing is maximized.
This is obtained by a medication delivery device for delivering medicine or other fluent material to a mammal body, having a housing accommodating a cartridge containing an amount of said medicine, comprising:
an elastomeric piston movable mounted in said cartridge, which elastomeric piston is moved from a proximal end of said cartridge to a distal end of said cartridge by rotating at least a part of a first telescopic piston rod, which first telescopic piston rod has a distal part abutting said elastomeric piston and a proximal part rotatably mounted in said housing and a plurality of parts there between, said parts being connected to each other by mating threads,
drive means for rotating said first telescopic piston rod, such that said elastomeric piston moves forward inside said cartridge and expels an amount of said medicine, and
means preventing said elastomeric piston from rotating when said part of said first telescopic piston rod is rotated,
which medication delivery device according to the invention is characterized in that
said means preventing said elastomeric piston from rotating when at least a part of said first telescopic piston rod is rotated comprises an additional telescopic piston rod having a proximal end mounted in said housing and a distal end abutting said elastomeric piston.
When a telescopic piston rod is used, the elastomeric piston most be prevented from rotating in order to be advanced inside the cartridge. If an additional piston rod abutting the elastomeric piston is located in the cartridge this will effectively hinder the elastomeric piston from rotating when the first piston rod is expanded. Both piston rods can be made with a very little diameter, such that they both at the same time can fit into the interior of a standard cartridge. Since they are both fitted into the same cartridge, the addition of the diameter of both the telescopic piston rods is substantially smaller than the interior diameter of the cartridge, thereby leaving some non-occupied space both in the cartridge and in the housing of the medication delivery device.
In the present context the term 'elastomeric piston' is taken to mean a displaceable plate or cylinder that fits tightly to the inner walls of a cartridge. One surface of the elastomeric piston is in contact with the contents of the cartridge while the opposite surface is in contact with a piston rod.
The term 'piston rod' is in the present context taken to be the element which are used to ap- ply pressure to a surface of the elastomeric piston, such that the elastomeric piston is being displaced and the contents of the cartridge is being expelled,
The term 'telescopic piston rod' is taken to mean a piston rod made up from a number of individual parts or pieces, which parts or pieces preferably has a circular cross-section, but the parts could if wanted be of any desired form. All the pieces, although the most distal part or
piece could be solid is preferably hollow thereby creating an interior compartment in each part or piece, which compartment has a diameter or a width large enough to fit the neighbouring piece into the compartment such that the telescopic piston rod can be transformed from a position where all the pieces are contained in the compartment of the neighbouring piece to a position where all the pieces are extracted out of the compartments or almost of the compartments In the first position the overall length of the telescopic piston rod is somewhat equal to the length of the longest part or piece, and in the extracted position the length of the telescopic piston rod almost equals the total sum of the length of each individual piece
In the present context, the term 'abutting the elastomeric piston' or 'elastomeric piston in contact with a piston rod' is taken to mean that the piston rod may or may not be fixed to the movable elastomeric piston In both cases the piston rod has the ability to displace the elastomeric piston at least in a direction towards the outlet of the cartridge When, as disclosed in claim 2, the additional telescopic piston rod is rotatably mounted in the housing, it is ensured that a telescopic piston rod equal to the first telescopic piston rod can be utilized as the additional telescopic piston rod
When, as disclosed in claim 3, the additional telescopic piston rod extends parallel with the first piston rod inside said cartridge, it is ensured that the construction of the bearings can be kept simple The bearings carrying the rotating parts of the telescopic piston rods can e g be ball bearings as shown or a combination of a ball bearing and a needle bearing located at the proximal end of the telescopic piston rod If the two telescopic piston rods crosses each other inside the cartridge, or if they in any other way are kept non-parallel, the design of the bear- ings will be much more complicated
When, as disclosed in claim 4 the first telescopic piston rod and said additional telescopic piston rod is connected to each other through a synchronisation gear such that both telescopic pistons rods rotates with the same rotational speed, and that one of said telescopic piston rods is rotated by an electrical motor which drives one of said telescopic piston rod through a driving gear, it is ensured that although the electrical motor only drives one of the two telescopic piston rods they are both rotated with the same rotational speed If the pitch of the threads connecting the pieces of each telescopic piston rod is the same for both telescopic piston rods it is ensured that the distal end of each telescopic piston rod moves at the same speed If the synchronization utilizes only two gear wheels, as shown, the first tele-
scopic piston rod and the additional telescopic piston rod will rotate in different directions When the two telescopic piston rods are moving in different directions, the momentum deliv¬ ered to the elastomeric piston from the one telescopic piston rod being driven by the electrical motor will be equalized by the momentum delivered from the other telescopic piston rod and the resulting momentum working on the elastomeric piston will be zero If an uneven number of gearing wheels are utilized, the two telescopic piston rods will rotate in the same direction which will build up a momentum at the point where the telescopic piston rods is secured in the housing
In an embodiment of the medication delivery device according to the invention, the first telescopic piston rod and said additional telescopic piston rod each comprises of three parts, a first part having an interior thread, a third part having an exterior thread and an intermediate second part having an exterior thread mating said interior thread of said first part and an interior thread mating said exterior thread of said third part Having a telescopic piston rod made up from three parts have been found to provide a length and a stability suitable for a medication delivery device
When, as disclosed in claim 6, the first part of said first telescopic piston rod and said first part of said additional telescopic piston rod is located at said proximal end of said cartridge, and that said third part of said first telescopic piston rod and said third part of said additional telescopic piston rod is moving towards said distal end of said cartridge, it is ensured that the piece of each telescopic piston rod having the largest diameter and containing the other pieces of the telescopic piston rod is the piece located at the most proximal end of the medication delivery device
The direction of the pith of the threads provided on the pieces making up each telescopic piston rod determines in which direction each telescopic piston rod moves when the first piece is being rotated In an embodiment of the medication delivery device according to the invention, the direction of said threads of said first telescopic piston rod and said additional tele- scopic piston rod is such that said distal end of each telescopic piston rod travels in the same direction inside said cartridge when one of said telescopic piston rods is rotated If as mentioned in claim 8 the first telescopic piston rod and said additional telescopic piston rod rotates in the same direction, the threads of each telescopic piston rod most be in the same direction whereas if the first telescopic piston rod and said additional telescopic piston rod
rotates in opposite directions, as mentioned in claim 9, the thread of each telescopic piston rod most be in opposite directions
When, as disclosed in claim 10, the first telescopic piston rod at said distal end is connected to said distal end of said additional telescopic piston rod preferably through a circular plate abutting said elastomeric piston inside said cartridge, it is ensured that the two telescopic piston rods are locked to each other and that the momentum is adequate balanced between the two telescopic piston rods
Brief Description of the Drawings:
The invention will be explained more fully below in connection with a preferred embodiment and with reference to the drawings in which
Figure 1 Shows a perspective view of the medication delivery device according to the invention
Figure 2 Shows a sectional view along line B-B in figure 3
Figure 3 Shows a sectional view along line A-A in figure 2
Figure 4 Shows a cross-sectional view of the prior art medication delivery device
Figure 5 Shows a cross-sectional iew of the medication delivery device according to the present invention
The figures are schematic and simplified for clarity, and they just show details, which are essential to the understanding of the invention, while other details are left out Throughout, the same reference numerals are used for identical or corresponding parts
Detailed Description of Embodiments:
Initially it may be convenient to define that, the term "distal end" of the housing 1 and of the cartridge 2 is meant to refer to the end carrying the conduit through which the medicine is expelled, whereas the term "proximal end" is meant to refer to the opposite end carrying the drive mechanism
Figure 1 to 3 shows a medical injection device comprising a housing 1 accommodating a cartridge 2 containing the fluent medicine to be injected An elastomeric piston 3 is movable mounted inside the cartridge 2 The fluent medicine will be expelled when the movable elas- tomenc piston 3 is moved towards the distal end of the medical injection device
The elastomeric piston 3 is moved forward by a first telescopic piston rod 4 made up from three parts 5, 6 7 The first part 5 has an interior thread mating the exterior thread of the second intermediate part 6 The second intermediate part 6 is in addition provided with an interior thread mating the exterior thread of the third part 7 When the first part 5 is rotated, and the elastomeric piston 3 as well as the third part 7 of the first telescopic piston rod 4 is locked against rotation, the second intermediate part 6 and the third part 7 will be moved in the distal direction due to the mating threads This will cause the elastomeric piston 3 to move in the distal direction and expel the medicine contained in the cartridge 2
Rotating the first part 5 of the first telescopic piston rod 4 is done by an electrical motor 8 which is coupled to the first part 5 of the first telescopic piston rod 4 through a number of gearing wheels 9, 10, 1 1 The first part 5 of the telescopic piston rod is rotatably mounted in the housing 1 through a number of ball bearings 12 Other types of bearings can off cause be used if so wanted
Locking the elastomeric piston 3 and the first part 5 of the telescopic piston rod 4 against rotation can be done in many different ways In the embodiment shown in the figures the locking is realized by providing an additional telescopic piston rod 14 This additional telescopic piston rod 14 is made up in the same manner as the first telescopic piston rod 4 and comprises three parts 15, 16, 17, which is connected together by mating threads
The third part 17 of the additional telescopic piston rod 14 is at the distal end connected to the first telescopic piston rod 4 through a circular plate 18 having a distal side abutting the elastomenc piston 3, and the first part 15 of the additional telescopic piston rod 14 is rotatably mounted in the housing 1 by a number of ball bearιngs19
The additional telescopic piston rod 14, which sole purpose is to prevent the elastomeric piston 3 and the third part 7 of the first telescopic piston rod 4 from rotating when the first part 5 of the first telescopic piston rod 4 is rotated, can either be made as a dummy slave following
the longitudinal movement of the first telescopic piston rod 4, or it can be fully synchronized with the first telescopic piston rod 4
When the additional telescopic piston rod 14 is made as a dummy slave it is preferably made without any threads and connected to the first telescopic piston rod only through the circular plate 18, or by other means only transmitting the longitudinal movement from the first telescopic piston rod 4 to the additional telescopic piston rod 14 Since only longitudinal movement is transmitted, the first part 15 of the additional telescopic piston 14 rod need not be rotational mounted in the housing 1
When the additional telescopic piston rod 14 is synchronized with the first telescopic piston rod 4, the synchronisation can be done by providing the first telescopic piston rod 4 and the additional telescopic piston rod 14 with a synchronization gear made up from a first gear wheel 20 connected to the first telescopic piston rod 4 and a second gear wheel 21 con- nected to the additional telescopic piston rod 14, which two gear wheels 20,21 interconnects with each other
If the synchronisation utilizes only two gear wheels 20, 21 interconnecting each other, the first telescopic piston rod 4 and the additional piston rod 14 will rotate in different directions, which will cause the momentum delivered from the first telescopic piston rod 4 to be equalized by the momentum delivered from the additional telescopic piston rod 14, such that the resulting momentum working on the circular plate 18 will be zero
If the additional telescopic piston rod 14 is made as a dummy slave following the longitudinal movement of the first telescopic piston rod 4, or if an additional gear wheel is provided between the two gear wheels 20, 21 such that the first telescopic piston rod 4 and the additional telescopic piston rod 14 rotates in the same direction stress will build up in the additional telescopic piston rod 14, and a momentum will occur at the point where the additional telescopic piston rod 14 is secured in the housing 1 This unwanted momentum is however sim- ply prevented by rotating the first telescopic piston rod 4 and the additional telescopic piston rod 14 in opposite directions
The mating threads connecting the three parts 5, 6, 7 of the first telescopic piston rod 4 and the mating threads connecting the three parts 15, 16, 7 of the additional telescopic piston rod 14 has to be in a direction which will cause the distal end of both the first telescopic piston
rod 4 and the distal end of the additional telescopic piston rod 14 to move in the distal direction inside the cartridge when the first part 5 of the first telescopic piston rod 4 is rotated
Figure 4 shows a cross-sectional view of the prior art medication delivery device shown in figure 3B in WO 97 00091 As can be seen the outside diameter of the outer bushing 23 is somewhat equal to the interior diameter of the cartridge 24 The outside diameter of the outer bushing protrudes into the housingl of the medication delivery device, leaving no space for the remaining parts of the medication delivery device
Figure 5 shows a cross-sectional view of the medication delivery device of the present invention Since both telescopic piston rods 4J4 are fitted into the same cartridge 2, the largest outside diameter of each telescopic piston rod 4,14 has to be substantially smaller than the interior diameter of the cartridge 2 Since the largest outside diameter of each telescopic piston rod 4,14 protrudes into the housing 1 a large amount of non-occupied space is available inside the housing 1 in comparison with the prior art medication delivery device
Some preferred embodiments have been shown in the foregoing, but it should be stressed that the invention is not limited to these, but may be embodied in other ways within the subject-matter defined in the following claims
All though the present invention has been described in relation to an injector type device the scope of the claims are not in any way limited to such an injector type device, but may e g also include a medication pump for continuous delivery of a liquid medication
Claims
Claims:
1 A medication delivery device for delivering medicine or other fluent material to a mammal body, having a housing (1 ) accommodating a cartridge (2) containing an amount of said medicine, comprising
an elastomenc piston (3) movable mounted in said cartridge (2), which elastomeric piston (3) is moved from a proximal end of said cartridge (2) towards a distal end of said cartridge (2) by rotating at least a part (5) of a first telescopic piston rod (4), which first telescopic piston rod (4) has a distal part (7) abutting said elastomeric piston (3) and a proximal part (5) rotatably mounted in said housing (1 ) and a plurality of parts (6) there between, said parts (5,6,7) being connected to each other by mating threads,
drive means (8,9,10, 1 1 ) for rotating said first telescopic piston rod (4), such that said elas- tomenc piston (3) moves forward inside said cartridge (2) and expels an amount of said medicine, and
means preventing said elastomeric piston (3) from rotating when said part (5) of said first telescopic piston rod (4) is rotated,
characterized in that
said means preventing said elastomeric piston (3) from rotating when at least a part (5) of said first telescopic piston rod (4) is rotated comprises an additional telescopic piston rod (14) having a proximal end mounted in said housing (1 ) and a distal end abutting said elastome c piston (3)
2 A medication delivery device according to claim 1 , characterized in that said additional telescopic piston rod (14) is rotatably mounted in said housing (1 )
3 A medication delivery device according to claim 1 or 2, characterized in that said additional telescopic piston rod (14) extends parallel with said first piston rod (4) inside said cartridge (2)
4 A medication delivery device according to anyone of the claims 1-3, characterized in that said first telescopic piston rod (4) and said additional telescopic piston rod (14) is connected to each other through a synchronisation gear (20,21), such that both telescopic pistons rods (4,14) rotates with the same rotational speed, and that one of said telescopic piston rods (4,14) is rotated by an electrical motor (8) which drives one of said telescopic piston rod (4,14) through a driving gear (9, 10,1 1 )
5 A medication delivery device according to anyone of the claims 1-4, characterized in that said first telescopic piston rod 4 and said additional telescopic piston rod (14) each com- prises of three parts (5,6 7,15,16, 17), a first part (5, 15) having an interior thread, a third part (7,17) having an exterior thread and an intermediate second part (6, 16) having an exterior thread mating said interior thread of said first part (5,15) and an interior thread mating said exterior thread of said third part (7,17)
6 A medication delivery device according to claim 5, characterized in that said first part (5) of said first telescopic piston rod (4) and said first part (15) of said additional telescopic piston rod (14) is located at said proximal end of said cartridge (2), and that said third part (7) of said first telescopic piston rod (4) and said third part (17) of said additional telescopic piston rod (14) is moving towards said distal end of said cartridge (2)
7 A medication delivery device according to claim 5 or 6, characterized in that the direction of said threads of said first telescopic piston rod (4) and said additional telescopic piston rod (14) is such that said distal end of each telescopic piston rod (4,14) travels in the same direction inside said cartridge (2) when one of said telescopic piston rods (4, 14) is rotated
8 A medication delivery device according to claim 7, characterized in that said first telescopic piston (4) and said additional telescopic piston rod (14) rotates in the same direction
9 A medication delivery device according to claim 7, characterized in that said first tele- scopic piston (4) and said additional telescopic piston rod (14) rotates in opposite directions
10 A medication delivery device according to anyone of the preceding claims, characterized in that said first telescopic piston rod (4) at said distal end is connected to said distal end of said additional telescopic piston rod (14) preferably through a circular plate (18) abutting said elastomenc piston (3) inside said cartridge (2)
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2002537366A JP2004512100A (en) | 2000-10-27 | 2001-10-23 | Drug ejection device with nested piston rod |
EP01980189A EP1333872A1 (en) | 2000-10-27 | 2001-10-23 | A medication delivery device with telescopic piston rod |
AU2002212090A AU2002212090A1 (en) | 2000-10-27 | 2001-10-23 | A medication delivery device with telescopic piston rod |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DKPA200001608 | 2000-10-27 | ||
DKPA200001608 | 2000-10-27 |
Publications (1)
Publication Number | Publication Date |
---|---|
WO2002034315A1 true WO2002034315A1 (en) | 2002-05-02 |
Family
ID=8159808
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/DK2001/000697 WO2002034315A1 (en) | 2000-10-27 | 2001-10-23 | A medication delivery device with telescopic piston rod |
Country Status (4)
Country | Link |
---|---|
EP (1) | EP1333872A1 (en) |
JP (1) | JP2004512100A (en) |
AU (1) | AU2002212090A1 (en) |
WO (1) | WO2002034315A1 (en) |
Cited By (32)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
USD702834S1 (en) | 2011-03-22 | 2014-04-15 | Medimop Medical Projects Ltd. | Cartridge for use in injection device |
US8915882B2 (en) | 2010-01-19 | 2014-12-23 | Medimop Medical Projects Ltd. | Needle assembly for drug pump |
US9011164B2 (en) | 2013-04-30 | 2015-04-21 | Medimop Medical Projects Ltd. | Clip contact for easy installation of printed circuit board PCB |
US9072827B2 (en) | 2012-03-26 | 2015-07-07 | Medimop Medical Projects Ltd. | Fail safe point protector for needle safety flap |
US9173997B2 (en) | 2007-10-02 | 2015-11-03 | Medimop Medical Projects Ltd. | External drug pump |
US9259532B2 (en) | 2010-01-19 | 2016-02-16 | Medimop Medical Projects Ltd. | Cartridge interface assembly |
US9345836B2 (en) | 2007-10-02 | 2016-05-24 | Medimop Medical Projects Ltd. | Disengagement resistant telescoping assembly and unidirectional method of assembly for such |
US9421323B2 (en) | 2013-01-03 | 2016-08-23 | Medimop Medical Projects Ltd. | Door and doorstop for portable one use drug delivery apparatus |
US9452261B2 (en) | 2010-05-10 | 2016-09-27 | Medimop Medical Projects Ltd. | Low volume accurate injector |
US9572926B2 (en) | 2009-09-15 | 2017-02-21 | Medimop Medical Projects Ltd. | Cartridge insertion assembly |
US9656019B2 (en) | 2007-10-02 | 2017-05-23 | Medimop Medical Projects Ltd. | Apparatuses for securing components of a drug delivery system during transport and methods of using same |
US9987432B2 (en) | 2015-09-22 | 2018-06-05 | West Pharma. Services IL, Ltd. | Rotation resistant friction adapter for plunger driver of drug delivery device |
US10071196B2 (en) | 2012-05-15 | 2018-09-11 | West Pharma. Services IL, Ltd. | Method for selectively powering a battery-operated drug-delivery device and device therefor |
US10071198B2 (en) | 2012-11-02 | 2018-09-11 | West Pharma. Servicees IL, Ltd. | Adhesive structure for medical device |
US10137254B2 (en) | 2014-05-02 | 2018-11-27 | Novo Nordisk A/S | Telescopic drive arrangement for drug delivery device |
US10149943B2 (en) | 2015-05-29 | 2018-12-11 | West Pharma. Services IL, Ltd. | Linear rotation stabilizer for a telescoping syringe stopper driverdriving assembly |
US10293120B2 (en) | 2015-04-10 | 2019-05-21 | West Pharma. Services IL, Ltd. | Redundant injection device status indication |
US10420880B2 (en) | 2007-10-02 | 2019-09-24 | West Pharma. Services IL, Ltd. | Key for securing components of a drug delivery system during assembly and/or transport and methods of using same |
CN113414115A (en) * | 2021-07-14 | 2021-09-21 | 辛桂鑫 | Intelligent logistics sorting machine |
US11167086B2 (en) | 2008-09-15 | 2021-11-09 | West Pharma. Services IL, Ltd. | Stabilized pen injector |
US11311674B2 (en) | 2016-01-21 | 2022-04-26 | West Pharma. Services IL, Ltd. | Medicament delivery device comprising a visual indicator |
US11318254B2 (en) | 2015-10-09 | 2022-05-03 | West Pharma. Services IL, Ltd. | Injector needle cap remover |
US11338090B2 (en) | 2016-08-01 | 2022-05-24 | West Pharma. Services IL, Ltd. | Anti-rotation cartridge pin |
US11364337B2 (en) | 2016-01-21 | 2022-06-21 | West Pharma. Services IL, Ltd. | Force containment in an automatic injector |
US11389597B2 (en) | 2016-03-16 | 2022-07-19 | West Pharma. Services IL, Ltd. | Staged telescopic screw assembly having different visual indicators |
US11547802B2 (en) | 2015-10-09 | 2023-01-10 | West Pharma. Services IL, Ltd. | Angled syringe patch injector |
US11672904B2 (en) | 2016-01-21 | 2023-06-13 | West Pharma. Services IL, Ltd. | Needle insertion and retraction mechanism |
US11730892B2 (en) | 2016-08-01 | 2023-08-22 | West Pharma. Services IL, Ltd. | Partial door closure prevention spring |
US11819666B2 (en) | 2017-05-30 | 2023-11-21 | West Pharma. Services IL, Ltd. | Modular drive train for wearable injector |
US11819673B2 (en) | 2016-06-02 | 2023-11-21 | West Pharma. Services, IL, Ltd. | Three position needle retraction |
US11857767B2 (en) | 2017-12-22 | 2024-01-02 | West Pharma. Services IL, Ltd. | Injector usable with different dimension cartridges |
US11931552B2 (en) | 2015-06-04 | 2024-03-19 | West Pharma Services Il, Ltd. | Cartridge insertion for drug delivery device |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102966625A (en) * | 2012-06-20 | 2013-03-13 | 苏州世力源科技有限公司 | Anti-rotation structure and method for hydraulic cylinder |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1992010425A1 (en) * | 1990-12-14 | 1992-06-25 | Habley Medical Technology Corporation | Variable proportion dispenser |
WO1994015660A1 (en) * | 1993-01-05 | 1994-07-21 | Berney Jean Claude | Powered-plunger infusion device |
WO1997000091A1 (en) * | 1995-06-14 | 1997-01-03 | Berney Jean Claude | Linear-transmission syringe plunger |
WO2000015280A1 (en) * | 1998-09-15 | 2000-03-23 | Njc Innovations | Devices with power-driven syringe for administering therapeutic substances |
-
2001
- 2001-10-23 EP EP01980189A patent/EP1333872A1/en not_active Withdrawn
- 2001-10-23 WO PCT/DK2001/000697 patent/WO2002034315A1/en not_active Application Discontinuation
- 2001-10-23 AU AU2002212090A patent/AU2002212090A1/en not_active Abandoned
- 2001-10-23 JP JP2002537366A patent/JP2004512100A/en active Pending
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1992010425A1 (en) * | 1990-12-14 | 1992-06-25 | Habley Medical Technology Corporation | Variable proportion dispenser |
WO1994015660A1 (en) * | 1993-01-05 | 1994-07-21 | Berney Jean Claude | Powered-plunger infusion device |
WO1997000091A1 (en) * | 1995-06-14 | 1997-01-03 | Berney Jean Claude | Linear-transmission syringe plunger |
WO2000015280A1 (en) * | 1998-09-15 | 2000-03-23 | Njc Innovations | Devices with power-driven syringe for administering therapeutic substances |
Cited By (50)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9861759B2 (en) | 2007-10-02 | 2018-01-09 | Medimop Medical Projects Ltd. | External drug pump |
US9656019B2 (en) | 2007-10-02 | 2017-05-23 | Medimop Medical Projects Ltd. | Apparatuses for securing components of a drug delivery system during transport and methods of using same |
US10413679B2 (en) | 2007-10-02 | 2019-09-17 | West Pharma. Services IL, Ltd. | External drug pump |
US10384017B2 (en) | 2007-10-02 | 2019-08-20 | West Pharma. Services IL, Ltd. | Anti-rotation feature for infusion pump cartridge |
US9173997B2 (en) | 2007-10-02 | 2015-11-03 | Medimop Medical Projects Ltd. | External drug pump |
US10420880B2 (en) | 2007-10-02 | 2019-09-24 | West Pharma. Services IL, Ltd. | Key for securing components of a drug delivery system during assembly and/or transport and methods of using same |
US9782545B2 (en) | 2007-10-02 | 2017-10-10 | Medimop Medical Projects Ltd. | External drug pump |
US9345836B2 (en) | 2007-10-02 | 2016-05-24 | Medimop Medical Projects Ltd. | Disengagement resistant telescoping assembly and unidirectional method of assembly for such |
US11504481B2 (en) | 2007-10-02 | 2022-11-22 | West Pharma. Services IL, Ltd. | Anti-rotation feature for infusion pump cartridge |
US11590291B2 (en) | 2007-10-02 | 2023-02-28 | West Pharma. Services IL, Ltd. | External drug pump |
US11167086B2 (en) | 2008-09-15 | 2021-11-09 | West Pharma. Services IL, Ltd. | Stabilized pen injector |
US9572926B2 (en) | 2009-09-15 | 2017-02-21 | Medimop Medical Projects Ltd. | Cartridge insertion assembly |
US9259532B2 (en) | 2010-01-19 | 2016-02-16 | Medimop Medical Projects Ltd. | Cartridge interface assembly |
US9492610B2 (en) | 2010-01-19 | 2016-11-15 | MEDIMOP Projects Ltd. | Needle assembly for drug pump |
US9522234B2 (en) | 2010-01-19 | 2016-12-20 | Medimop Medical Projects Ltd. | Needle assembly for drug pump |
US9149575B2 (en) | 2010-01-19 | 2015-10-06 | Medimop Medical Projects Ltd. | Needle assembly for drug pump |
US8915882B2 (en) | 2010-01-19 | 2014-12-23 | Medimop Medical Projects Ltd. | Needle assembly for drug pump |
US9764092B2 (en) | 2010-01-19 | 2017-09-19 | Medimop Medical Projects Ltd. | Needle assembly for drug pump |
US9452261B2 (en) | 2010-05-10 | 2016-09-27 | Medimop Medical Projects Ltd. | Low volume accurate injector |
USD747799S1 (en) | 2011-03-22 | 2016-01-19 | Medimop Medical Projects Ltd. | Cartridge |
USD702834S1 (en) | 2011-03-22 | 2014-04-15 | Medimop Medical Projects Ltd. | Cartridge for use in injection device |
US9511190B2 (en) | 2012-03-26 | 2016-12-06 | Medimop Medical Projects Ltd. | Fail safe point protector for needle safety flap |
US9393365B2 (en) | 2012-03-26 | 2016-07-19 | Medimop Medical Projects Ltd. | Fail safe point protector for needle safety flap |
US9072827B2 (en) | 2012-03-26 | 2015-07-07 | Medimop Medical Projects Ltd. | Fail safe point protector for needle safety flap |
US10071196B2 (en) | 2012-05-15 | 2018-09-11 | West Pharma. Services IL, Ltd. | Method for selectively powering a battery-operated drug-delivery device and device therefor |
US10071198B2 (en) | 2012-11-02 | 2018-09-11 | West Pharma. Servicees IL, Ltd. | Adhesive structure for medical device |
US9421323B2 (en) | 2013-01-03 | 2016-08-23 | Medimop Medical Projects Ltd. | Door and doorstop for portable one use drug delivery apparatus |
US9166313B2 (en) | 2013-04-30 | 2015-10-20 | Medimop Medical Projects | Power supply contact for installation of printed circuit board |
US9011164B2 (en) | 2013-04-30 | 2015-04-21 | Medimop Medical Projects Ltd. | Clip contact for easy installation of printed circuit board PCB |
US10137254B2 (en) | 2014-05-02 | 2018-11-27 | Novo Nordisk A/S | Telescopic drive arrangement for drug delivery device |
US10293120B2 (en) | 2015-04-10 | 2019-05-21 | West Pharma. Services IL, Ltd. | Redundant injection device status indication |
US10149943B2 (en) | 2015-05-29 | 2018-12-11 | West Pharma. Services IL, Ltd. | Linear rotation stabilizer for a telescoping syringe stopper driverdriving assembly |
US11931552B2 (en) | 2015-06-04 | 2024-03-19 | West Pharma Services Il, Ltd. | Cartridge insertion for drug delivery device |
US9987432B2 (en) | 2015-09-22 | 2018-06-05 | West Pharma. Services IL, Ltd. | Rotation resistant friction adapter for plunger driver of drug delivery device |
US12036394B2 (en) | 2015-10-09 | 2024-07-16 | West Pharma. Services IL, Ltd. | Injector needle cap and/or liner remover |
US11318254B2 (en) | 2015-10-09 | 2022-05-03 | West Pharma. Services IL, Ltd. | Injector needle cap remover |
US11759573B2 (en) | 2015-10-09 | 2023-09-19 | West Pharma. Services, IL, Ltd. | Bent fluid path add on to a prefilled reservoir |
US11724034B2 (en) | 2015-10-09 | 2023-08-15 | West Pharma. Services, IL, Ltd. | Injector system |
US11547802B2 (en) | 2015-10-09 | 2023-01-10 | West Pharma. Services IL, Ltd. | Angled syringe patch injector |
US11672904B2 (en) | 2016-01-21 | 2023-06-13 | West Pharma. Services IL, Ltd. | Needle insertion and retraction mechanism |
US11364337B2 (en) | 2016-01-21 | 2022-06-21 | West Pharma. Services IL, Ltd. | Force containment in an automatic injector |
US12005237B2 (en) | 2016-01-21 | 2024-06-11 | West Pharma. Services IL, Ltd. | Medicament delivery device comprising a visual indicator |
US11311674B2 (en) | 2016-01-21 | 2022-04-26 | West Pharma. Services IL, Ltd. | Medicament delivery device comprising a visual indicator |
US11389597B2 (en) | 2016-03-16 | 2022-07-19 | West Pharma. Services IL, Ltd. | Staged telescopic screw assembly having different visual indicators |
US11819673B2 (en) | 2016-06-02 | 2023-11-21 | West Pharma. Services, IL, Ltd. | Three position needle retraction |
US11730892B2 (en) | 2016-08-01 | 2023-08-22 | West Pharma. Services IL, Ltd. | Partial door closure prevention spring |
US11338090B2 (en) | 2016-08-01 | 2022-05-24 | West Pharma. Services IL, Ltd. | Anti-rotation cartridge pin |
US11819666B2 (en) | 2017-05-30 | 2023-11-21 | West Pharma. Services IL, Ltd. | Modular drive train for wearable injector |
US11857767B2 (en) | 2017-12-22 | 2024-01-02 | West Pharma. Services IL, Ltd. | Injector usable with different dimension cartridges |
CN113414115A (en) * | 2021-07-14 | 2021-09-21 | 辛桂鑫 | Intelligent logistics sorting machine |
Also Published As
Publication number | Publication date |
---|---|
JP2004512100A (en) | 2004-04-22 |
AU2002212090A1 (en) | 2002-05-06 |
EP1333872A1 (en) | 2003-08-13 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
US6508788B2 (en) | Medication delivery device with telescopic piston rod | |
WO2002034315A1 (en) | A medication delivery device with telescopic piston rod | |
US9220835B2 (en) | Device for drug infusion | |
CN100563738C (en) | Has credit card sized injection device | |
EP1996260B1 (en) | An injection device having a gearing arrangement | |
CN102652024B (en) | Pad device and the method for container is filled with liquid drug | |
CN1255192C (en) | Medical arrangement | |
US8202256B2 (en) | Injection device | |
CN101912649B (en) | Device for injecting apportioned doses of liquid drug | |
DK2391408T3 (en) | PORTABLE MEDICAL FLUID ADMINISTRATION WITH DRIVE SCREW LED CONNECTOR WITH CONTAINER STAMP | |
CN103228307B (en) | The drug delivery device of wheel operation | |
JP2003534062A (en) | Medical equipment | |
JP2017502809A (en) | Transmission mechanism for a motor-driven drug delivery device | |
EP2579917B1 (en) | A device for simultaneous infusion of drugs into multiple infusion sites | |
RU2750676C1 (en) | Method and devices for injection of insulin | |
US6610029B1 (en) | Needle-less injecting device | |
US20180028752A1 (en) | Compact medical pump device | |
KR101615745B1 (en) | Drug infusion pump including stackable curved syringe |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
DFPE | Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101) | ||
121 | Ep: the epo has been informed by wipo that ep was designated in this application | ||
WWE | Wipo information: entry into national phase |
Ref document number: 2001980189 Country of ref document: EP |
|
WWE | Wipo information: entry into national phase |
Ref document number: 2002537366 Country of ref document: JP |
|
WWP | Wipo information: published in national office |
Ref document number: 2001980189 Country of ref document: EP |
|
REG | Reference to national code |
Ref country code: DE Ref legal event code: 8642 |
|
WWW | Wipo information: withdrawn in national office |
Ref document number: 2001980189 Country of ref document: EP |