WO2002019962A3 - Therapeutic and cosmetic uses of heparanases - Google Patents

Therapeutic and cosmetic uses of heparanases Download PDF

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Publication number
WO2002019962A3
WO2002019962A3 PCT/IL2001/000830 IL0100830W WO0219962A3 WO 2002019962 A3 WO2002019962 A3 WO 2002019962A3 IL 0100830 W IL0100830 W IL 0100830W WO 0219962 A3 WO0219962 A3 WO 0219962A3
Authority
WO
WIPO (PCT)
Prior art keywords
heparanases
therapeutic
cosmetic uses
cosmetic
heparanase
Prior art date
Application number
PCT/IL2001/000830
Other languages
French (fr)
Other versions
WO2002019962A2 (en
Inventor
Neta Ilan
Israel Vlodavsky
Oron Yacoby-Zeevi
Iris Pecker
Original Assignee
Insight Strategy And Marketing
Hadasit Med Res Service
Neta Ilan
Israel Vlodavsky
Oron Yacoby-Zeevi
Iris Pecker
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Insight Strategy And Marketing, Hadasit Med Res Service, Neta Ilan, Israel Vlodavsky, Oron Yacoby-Zeevi, Iris Pecker filed Critical Insight Strategy And Marketing
Priority to EP01963360A priority Critical patent/EP1317271A4/en
Priority to AU2001284380A priority patent/AU2001284380A1/en
Publication of WO2002019962A2 publication Critical patent/WO2002019962A2/en
Publication of WO2002019962A3 publication Critical patent/WO2002019962A3/en
Priority to US10/341,582 priority patent/US20030161823A1/en
Priority to US10/781,758 priority patent/US20040146497A1/en
Priority to US11/106,672 priority patent/US20050260187A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/47—Hydrolases (3) acting on glycosyl compounds (3.2), e.g. cellulases, lactases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like

Abstract

Methods and compositions for inducing and/or accelerating wound healing and/or angiogenesis via the catalytic activity of heparanase are disclosed.
PCT/IL2001/000830 1997-09-02 2001-09-05 Therapeutic and cosmetic uses of heparanases WO2002019962A2 (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
EP01963360A EP1317271A4 (en) 2000-09-11 2001-09-05 Therapeutic and cosmetic uses of heparanases
AU2001284380A AU2001284380A1 (en) 2000-09-11 2001-09-05 Therapeutic and cosmetic uses of heparanases
US10/341,582 US20030161823A1 (en) 1998-08-31 2003-01-14 Therapeutic and cosmetic uses of heparanases
US10/781,758 US20040146497A1 (en) 1997-09-02 2004-02-20 Therapeutic and cosmetic uses of heparanases
US11/106,672 US20050260187A1 (en) 1998-08-31 2005-04-15 Therapeutic and cosmetic uses of heparanases

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US23155100P 2000-09-11 2000-09-11
US60/231,551 2000-09-11
US24459300P 2000-11-01 2000-11-01
US60/244,593 2000-11-01
US09/727,479 2000-12-04
US09/727,479 US20020068054A1 (en) 2000-09-11 2000-12-04 Therapeutic and cosmetic uses of heparanases

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
US09/727,479 Continuation-In-Part US20020068054A1 (en) 1998-08-31 2000-12-04 Therapeutic and cosmetic uses of heparanases

Related Child Applications (1)

Application Number Title Priority Date Filing Date
US10/341,582 Continuation-In-Part US20030161823A1 (en) 1997-09-02 2003-01-14 Therapeutic and cosmetic uses of heparanases

Publications (2)

Publication Number Publication Date
WO2002019962A2 WO2002019962A2 (en) 2002-03-14
WO2002019962A3 true WO2002019962A3 (en) 2002-07-11

Family

ID=27398198

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IL2001/000830 WO2002019962A2 (en) 1997-09-02 2001-09-05 Therapeutic and cosmetic uses of heparanases

Country Status (4)

Country Link
US (1) US20020068054A1 (en)
EP (1) EP1317271A4 (en)
AU (1) AU2001284380A1 (en)
WO (1) WO2002019962A2 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6699672B1 (en) 1997-09-02 2004-03-02 Insight Biopharmaceuticals Ltd. Heparanase specific molecular probes and their use research and medical applications
EP1157118A4 (en) * 1999-03-01 2002-07-17 Insight Strategy & Marketing Polynucleotide encoding a polypeptide having heparanase activity and expression of same in genetically modified cells
IL150721A0 (en) * 2002-07-11 2003-02-12 Hadasit Med Res Service Method and compositions for regulating mammalian hair growth
IL150829A0 (en) * 2002-07-21 2003-02-12 Yissum Res Dev Co Method and compositions for treatment of bone disorders
WO2005074655A2 (en) * 2004-01-30 2005-08-18 Emory University Materials and method for promotion of nerve regeneration
KR100560407B1 (en) * 2004-03-11 2006-03-13 주식회사 태평양 Yoghurt-like cosmetic compositions

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999021975A1 (en) * 1997-10-28 1999-05-06 The Australian National University Isolated nucleic acid molecule encoding mammalian endoglucuronidase and uses therefor
US5968822A (en) * 1997-09-02 1999-10-19 Pecker; Iris Polynucleotide encoding a polypeptide having heparanase activity and expression of same in transduced cells

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2819129A1 (en) * 1978-04-29 1979-11-15 Koehler Valentin Topical compositions e.g. ointment contg. beta-glucuronidase - for treatment of non-infectious skin disorders e.g. psoriasis
KR927003090A (en) * 1989-08-23 1992-12-17 하다사 메디칼 오르가니제이션 Wound Healing Agents Including Heparin Enzyme
US6348344B1 (en) * 1997-09-02 2002-02-19 Insight Strategy & Marketing Ltd. Genetically modified cells and methods for expressing recombinant heparanase and methods of purifying same
GB9802725D0 (en) * 1998-02-09 1998-04-08 Ciba Geigy Ag Organic compounds

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5968822A (en) * 1997-09-02 1999-10-19 Pecker; Iris Polynucleotide encoding a polypeptide having heparanase activity and expression of same in transduced cells
WO1999021975A1 (en) * 1997-10-28 1999-05-06 The Australian National University Isolated nucleic acid molecule encoding mammalian endoglucuronidase and uses therefor

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
See also references of EP1317271A4 *
TOYOSHIMA ET AL.: "Human heparanase (purification characterization cloning and expression)", J. BIOL. CHEM., vol. 274, no. 34, 1999, pages 24153 - 24160, XP002909911 *

Also Published As

Publication number Publication date
AU2001284380A1 (en) 2002-03-22
WO2002019962A2 (en) 2002-03-14
EP1317271A4 (en) 2005-06-29
EP1317271A2 (en) 2003-06-11
US20020068054A1 (en) 2002-06-06

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