WO2002002602A3 - Slgp protein and nucleic acid molecules and uses therefor - Google Patents

Slgp protein and nucleic acid molecules and uses therefor Download PDF

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Publication number
WO2002002602A3
WO2002002602A3 PCT/US2001/020751 US0120751W WO0202602A3 WO 2002002602 A3 WO2002002602 A3 WO 2002002602A3 US 0120751 W US0120751 W US 0120751W WO 0202602 A3 WO0202602 A3 WO 0202602A3
Authority
WO
WIPO (PCT)
Prior art keywords
slgp
nucleic acid
acid molecules
expression vectors
uses therefor
Prior art date
Application number
PCT/US2001/020751
Other languages
French (fr)
Other versions
WO2002002602A2 (en
WO2002002602A9 (en
Inventor
Fong-Ying Tsai
Original Assignee
Millennium Pharm Inc
Fong-Ying Tsai
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Millennium Pharm Inc, Fong-Ying Tsai filed Critical Millennium Pharm Inc
Priority to AU2001273077A priority Critical patent/AU2001273077A1/en
Priority to EP01952313A priority patent/EP1309686A2/en
Publication of WO2002002602A2 publication Critical patent/WO2002002602A2/en
Publication of WO2002002602A3 publication Critical patent/WO2002002602A3/en
Publication of WO2002002602A9 publication Critical patent/WO2002002602A9/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

The invention provides isolated nucleic acids molecules, designated SLGP nucleic acid molecules, which encode novel GPCR family members. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing SLGP nucleic acid molecules, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which an SLGP gene has been introduced or disrupted. The invention still further provides isolated SLGP proteins, fusion proteins, antigenic peptides and anti-SLGP antibodies. Diagnostic methods utilizing compositions of the invention are also provided.
PCT/US2001/020751 2000-06-30 2001-06-29 Slgp protein and nucleic acid molecules and uses therefor WO2002002602A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
AU2001273077A AU2001273077A1 (en) 2000-06-30 2001-06-29 Slgp protein and nucleic acid molecules and uses therefor
EP01952313A EP1309686A2 (en) 2000-06-30 2001-06-29 Slgp protein and nucleic acid molecules and uses therefor

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US60892100A 2000-06-30 2000-06-30
US09/608,921 2000-06-30

Publications (3)

Publication Number Publication Date
WO2002002602A2 WO2002002602A2 (en) 2002-01-10
WO2002002602A3 true WO2002002602A3 (en) 2002-08-22
WO2002002602A9 WO2002002602A9 (en) 2003-03-06

Family

ID=24438633

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/020751 WO2002002602A2 (en) 2000-06-30 2001-06-29 Slgp protein and nucleic acid molecules and uses therefor

Country Status (3)

Country Link
EP (1) EP1309686A2 (en)
AU (1) AU2001273077A1 (en)
WO (1) WO2002002602A2 (en)

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999014328A2 (en) * 1997-09-17 1999-03-25 Genentech, Inc. Secreted and transmembrane polypeptides and nucleic acids encoding the same
WO2000018923A2 (en) * 1998-09-30 2000-04-06 Millennium Pharmaceuticals, Inc. Slgp protein and nucleic acid molecule and uses therefor
WO2000053753A2 (en) * 1999-03-08 2000-09-14 Genentech, Inc. Promotion or inhibition of angiogenesis and cardiovascularization
WO2001060999A1 (en) * 2000-02-14 2001-08-23 Imclone Systems Incorporated Nucleic acid sequences characteristic of hematopoietic stem cells

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999014328A2 (en) * 1997-09-17 1999-03-25 Genentech, Inc. Secreted and transmembrane polypeptides and nucleic acids encoding the same
WO2000018923A2 (en) * 1998-09-30 2000-04-06 Millennium Pharmaceuticals, Inc. Slgp protein and nucleic acid molecule and uses therefor
WO2000053753A2 (en) * 1999-03-08 2000-09-14 Genentech, Inc. Promotion or inhibition of angiogenesis and cardiovascularization
WO2001060999A1 (en) * 2000-02-14 2001-08-23 Imclone Systems Incorporated Nucleic acid sequences characteristic of hematopoietic stem cells

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
BAUD ET AL: "EMR1, an Unusual Member in the Family of Hormone Receptors with Seven Transmembrane Segments", GENOMICS, ACADEMIC PRESS, SAN DIEGO, US, vol. 26, no. 2, 20 March 1995 (1995-03-20), pages 334 - 344, XP002118914, ISSN: 0888-7543 *
DATABASE EMBL [online] 12 December 1999 (1999-12-12), NCI-CGAP: "uo01f05.y1 NCI_CGAP_Mam6 Mus musculus cDNA clone IMAGE:2582145 5' similar to TR:O35818 O35818 CALCIUM-INDEPENDENT ALPHA-LATROTOXIN RECEPTOR. [1] ;, mRNA sequence.", XP002196808, Database accession no. AW213222 *
DATABASE EMBL [online] 16 June 2001 (2001-06-16), TERSKIKH A V ET AL: "Mus musculus ETL1 mRNA, complete cds.", XP002196806, Database accession no. AF385682 *
DATABASE EMBL [online] 19 April 2000 (2000-04-19), MARRA M ET AL: "un74g10.x1 Sugano mouse kidney mkia Mus musculus cDNA clone IMAGE:2536674 3', mRNA sequence.", XP002196807, Database accession no. AW701105 *
LEE D K ET AL: "Cloning and characterization of additional members of the G protein-coupled receptor family", BIOCHIMICA ET BIOPHYSICA ACTA. GENE STRUCTURE AND EXPRESSION, ELSEVIER, AMSTERDAM, NL, vol. 1490, no. 3, 29 February 2000 (2000-02-29), pages 311 - 323, XP004275600, ISSN: 0167-4781 *
TAKADA YOSHIO ET AL: "Cloning of cDNAs encoding G protein-coupled receptor expressed in human endothelial cells exposed to fluid shear stress.", BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, vol. 240, no. 3, 26 November 1997 (1997-11-26), pages 737 - 741, XP002196805, ISSN: 0006-291X *

Also Published As

Publication number Publication date
WO2002002602A2 (en) 2002-01-10
WO2002002602A9 (en) 2003-03-06
EP1309686A2 (en) 2003-05-14
AU2001273077A1 (en) 2002-01-14

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