WO2000057907A3 - Multivalent dengue virus vaccine - Google Patents
Multivalent dengue virus vaccine Download PDFInfo
- Publication number
- WO2000057907A3 WO2000057907A3 PCT/US2000/008199 US0008199W WO0057907A3 WO 2000057907 A3 WO2000057907 A3 WO 2000057907A3 US 0008199 W US0008199 W US 0008199W WO 0057907 A3 WO0057907 A3 WO 0057907A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- dengue
- virus
- dengue virus
- virus vaccine
- attenuated
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5254—Virus avirulent or attenuated
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/70—Multivalent vaccine
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/24011—Flaviviridae
- C12N2770/24111—Flavivirus, e.g. yellow fever virus, dengue, JEV
- C12N2770/24134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/24011—Flaviviridae
- C12N2770/24111—Flavivirus, e.g. yellow fever virus, dengue, JEV
- C12N2770/24161—Methods of inactivation or attenuation
- C12N2770/24164—Methods of inactivation or attenuation by serial passage
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Virology (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Priority Applications (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CA 2368674 CA2368674A1 (en) | 1999-03-26 | 2000-03-24 | Multivalent dengue virus vaccine |
JP2000607657A JP2002540168A (en) | 1999-03-26 | 2000-03-24 | Multivalent dengue virus vaccine |
DE60041250T DE60041250D1 (en) | 1999-03-26 | 2000-03-24 | MULTIVALENT DENGUE VIRUS VACCINE |
MXPA01009683A MXPA01009683A (en) | 1999-03-26 | 2000-03-24 | Multivalent dengue virus vaccine. |
AU40382/00A AU779280B2 (en) | 1999-03-26 | 2000-03-24 | Multivalent dengue virus vaccine |
BR0010969-0A BR0010969A (en) | 2000-03-24 | 2000-03-24 | Multipurpose Dengue Virus Vaccine |
EP00919748A EP1165127B1 (en) | 1999-03-26 | 2000-03-24 | Multivalent dengue virus vaccine |
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US12631399P | 1999-03-26 | 1999-03-26 | |
US60/126,313 | 1999-03-26 | ||
US18172400P | 2000-02-11 | 2000-02-11 | |
US60/181,724 | 2000-02-11 |
Publications (3)
Publication Number | Publication Date |
---|---|
WO2000057907A2 WO2000057907A2 (en) | 2000-10-05 |
WO2000057907A3 true WO2000057907A3 (en) | 2001-04-12 |
WO2000057907A9 WO2000057907A9 (en) | 2002-04-11 |
Family
ID=26824502
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2000/008199 WO2000057907A2 (en) | 1999-03-26 | 2000-03-24 | Multivalent dengue virus vaccine |
Country Status (12)
Country | Link |
---|---|
US (2) | US6638514B1 (en) |
EP (1) | EP1165127B1 (en) |
JP (1) | JP2002540168A (en) |
KR (1) | KR100721745B1 (en) |
CN (1) | CN1191092C (en) |
AT (1) | ATE419006T1 (en) |
AU (1) | AU779280B2 (en) |
CA (1) | CA2368674A1 (en) |
DE (1) | DE60041250D1 (en) |
ES (1) | ES2322327T3 (en) |
MX (1) | MXPA01009683A (en) |
WO (1) | WO2000057907A2 (en) |
Families Citing this family (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1165127B1 (en) * | 1999-03-26 | 2008-12-31 | Walter Reed Army Institute of Research | Multivalent dengue virus vaccine |
CA3060687C (en) * | 2001-05-22 | 2021-05-04 | The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Development of mutations useful for attenuating dengue viruses and chimeric dengue viruses |
EP1893637B1 (en) * | 2005-06-17 | 2016-01-06 | Sanofi Pasteur | Dengue serotype 1 attenuated strain |
WO2006134443A1 (en) | 2005-06-17 | 2006-12-21 | Sanofi Pasteur | Dengue serotype 2 attenuated strain |
FR2903605A1 (en) * | 2006-07-12 | 2008-01-18 | Sanofi Pasteur Sa | IMMUNIZATION METHOD AGAINST THE FOUR SEROTYPES OF DENGUE |
FR2906724B1 (en) * | 2006-10-04 | 2009-03-20 | Sanofi Pasteur Sa | METHOD OF IMMUNIZATION AGAINST THE 4 SEROTYPES OF DENGUE. |
FR2909286B1 (en) * | 2006-12-01 | 2012-06-08 | Sanofi Pasteur | IMMUNIZATION METHOD AGAINST THE 4 SEROTYPES OF DENGUE |
UY31437A1 (en) * | 2007-10-29 | 2009-05-29 | MYCOPLASMA BOVIS VACCINE AND SAME USE METHODS | |
WO2010075360A2 (en) * | 2008-12-22 | 2010-07-01 | The Children's Research Institute | Methods for detection of sepsis |
WO2010094663A1 (en) | 2009-02-17 | 2010-08-26 | Glaxosmithkline Biologicals S.A. | Inactivated dengue virus vaccine with aluminium-free adjuvant |
MY184428A (en) * | 2009-06-01 | 2021-04-01 | Inviragen Inc | Compositions and methods for administration of vaccines against dengue virus |
US8968996B2 (en) | 2009-06-01 | 2015-03-03 | Takeda Vaccines, Inc. | Compositions and methods for rapid immunization against dengue virus |
ES2436317T3 (en) | 2010-05-07 | 2013-12-30 | Deutsches Krebsforschungszentrum | Modified rodent parvovirus capable of spreading and spreading in human gliomas |
WO2014204892A1 (en) * | 2013-06-21 | 2014-12-24 | Merck Sharp & Dohme Corp. | Dengue virus vaccine compositions and methods of use thereof |
MY192543A (en) | 2014-12-22 | 2022-08-26 | Merck Sharp & Dohme | Dengue virus vaccine compositions and methods of use thereof |
EP3316897A4 (en) | 2015-07-02 | 2019-03-13 | Primevax Immuno-Oncology, Inc. | Compositions and methods for combination therapy with dengue virus and dendritic cells |
MX2018003757A (en) | 2015-09-26 | 2018-09-21 | Primevax Immuno Oncology Inc | Compositions and methods for producing dendritic cells. |
BE1024160B9 (en) | 2015-12-22 | 2017-12-06 | Glaxosmithkline Biologicals Sa | IMMUNOGENIC FORMULATION |
CN105777877B (en) * | 2016-04-05 | 2019-03-12 | 首都医科大学 | Dengue virus E protein blocking peptide P4 and its application |
CN105801674B (en) * | 2016-04-05 | 2019-03-12 | 首都医科大学 | Dengue virus E protein blocking peptide P7 and its application |
CA3082779A1 (en) | 2016-11-16 | 2018-05-24 | PrimeVax Immuno-Oncology, Inc. | Combination immunotherapies for treatment of cancer |
EP3598865A4 (en) | 2017-03-08 | 2021-04-07 | University of Georgia Research Foundation, Inc. | Methods and compositions related to increased viral production |
MX2019015194A (en) * | 2017-06-15 | 2020-08-03 | Primevax Immuno Oncology Inc | Compositions and methods for cancer therapy with dengue virus and dendritic cells. |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1996040933A1 (en) * | 1995-06-07 | 1996-12-19 | The Government Of The United States Of America, Represented By The Secretary Department Of Health And Human Services | Infectious dengue 2 virus pdk-53 as quadravalent vaccine |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH06181792A (en) * | 1992-06-05 | 1994-07-05 | Nippon Zeon Co Ltd | Production of noninfectious structural particle containing surface antigen protein of virus belonging to flavivirus family and recombinant virus using therefor |
US5723130A (en) * | 1993-05-25 | 1998-03-03 | Hancock; Gerald E. | Adjuvants for vaccines against respiratory syncytial virus |
JP2001525797A (en) * | 1996-10-28 | 2001-12-11 | ザ ユニバーシティ オブ ワシントン | Induction of viral mutation by incorporation of a miscoding ribonucleoside analog into viral RNA |
EP1165127B1 (en) * | 1999-03-26 | 2008-12-31 | Walter Reed Army Institute of Research | Multivalent dengue virus vaccine |
-
2000
- 2000-03-24 EP EP00919748A patent/EP1165127B1/en not_active Expired - Lifetime
- 2000-03-24 JP JP2000607657A patent/JP2002540168A/en active Pending
- 2000-03-24 CN CNB008079951A patent/CN1191092C/en not_active Expired - Fee Related
- 2000-03-24 KR KR1020017012302A patent/KR100721745B1/en not_active IP Right Cessation
- 2000-03-24 DE DE60041250T patent/DE60041250D1/en not_active Expired - Fee Related
- 2000-03-24 AT AT00919748T patent/ATE419006T1/en not_active IP Right Cessation
- 2000-03-24 US US09/535,117 patent/US6638514B1/en not_active Expired - Lifetime
- 2000-03-24 CA CA 2368674 patent/CA2368674A1/en not_active Abandoned
- 2000-03-24 WO PCT/US2000/008199 patent/WO2000057907A2/en active IP Right Grant
- 2000-03-24 MX MXPA01009683A patent/MXPA01009683A/en active IP Right Grant
- 2000-03-24 ES ES00919748T patent/ES2322327T3/en not_active Expired - Lifetime
- 2000-03-24 AU AU40382/00A patent/AU779280B2/en not_active Ceased
-
2003
- 2003-07-24 US US10/626,315 patent/US7217418B2/en not_active Expired - Fee Related
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1996040933A1 (en) * | 1995-06-07 | 1996-12-19 | The Government Of The United States Of America, Represented By The Secretary Department Of Health And Human Services | Infectious dengue 2 virus pdk-53 as quadravalent vaccine |
Non-Patent Citations (7)
Title |
---|
BHAMARAPRAVATI N ET AL: "Live attenuated tetravalent dengue vaccine", VACCINE,GB,BUTTERWORTH SCIENTIFIC. GUILDFORD, vol. 18, March 2000 (2000-03-01), pages 44 - 47, XP004203589, ISSN: 0264-410X * |
GUBLER D J: "The global pandemic of dengue/dengue haemorrhagic fever: Curent status and prospects for the future.", ANNALS ACADEMY OF MEDICINE SINGAPORE, vol. 27, no. 2, March 1998 (1998-03-01), pages 227 - 234, XP000952639, ISSN: 0304-4602 * |
HOKE C H ET AL: "PREPARATION OF AN ATTENUATED DENGUE 4 (341750 CARIB) VIRUS VACCINE.II. SAFETY AND IMMUNOGENICITY IN HUMANS", AMERICAN JOURNAL OF TROPICAL MEDICINE & HYGIENE,LAWRENCE, KS,US, vol. 43, no. 2, August 1990 (1990-08-01), pages 219 - 226, XP000929757, ISSN: 0002-9637 * |
JIRAKANJANAKIT N ET AL: "The use of Toxorhynchites splendens for identification and quantitation of serotypes contained in the tetravalent live attenuated dengue vaccine", VACCINE,GB,BUTTERWORTH SCIENTIFIC. GUILDFORD, vol. 17, no. 6, February 1999 (1999-02-01), pages 597 - 601, XP004153818, ISSN: 0264-410X * |
MARCHETTE N J ET AL: "PREPARATION OF AN ATTENUATED DENGUE 4 (341750 CARIB) VIRUS VACCINE.I. PRE-CLINICAL STUDIES", AMERICAN JOURNAL OF TROPICAL MEDICINE & HYGIENE,LAWRENCE, KS,US, vol. 43, no. 2, August 1990 (1990-08-01), pages 212 - 218, XP000929758, ISSN: 0002-9637 * |
PURI BEENA ET AL: "Molecular analysis of dengue virus attenuation after serial passage in primary dog kidney cells.", JOURNAL OF GENERAL VIROLOGY, vol. 78, no. 9, 1997, pages 2287 - 2291, XP002149600, ISSN: 0022-1317 * |
PUTNAK ROBERT ET AL: "Development of a purified, inactivated, dengue-2 virus vaccine prototype in vero cells: Immunogenicity and protection in mice and rhesus monkeys.", JOURNAL OF INFECTIOUS DISEASES, vol. 174, no. 6, 1996, pages 1176 - 1184, XP000952637, ISSN: 0022-1899 * |
Also Published As
Publication number | Publication date |
---|---|
ES2322327T3 (en) | 2009-06-19 |
US7217418B2 (en) | 2007-05-15 |
KR100721745B1 (en) | 2007-05-25 |
DE60041250D1 (en) | 2009-02-12 |
EP1165127B1 (en) | 2008-12-31 |
MXPA01009683A (en) | 2003-06-24 |
JP2002540168A (en) | 2002-11-26 |
CN1191092C (en) | 2005-03-02 |
WO2000057907A2 (en) | 2000-10-05 |
CN1351502A (en) | 2002-05-29 |
ATE419006T1 (en) | 2009-01-15 |
KR20020008136A (en) | 2002-01-29 |
US6638514B1 (en) | 2003-10-28 |
WO2000057907A9 (en) | 2002-04-11 |
AU4038200A (en) | 2000-10-16 |
US20070087015A1 (en) | 2007-04-19 |
CA2368674A1 (en) | 2000-10-05 |
EP1165127A2 (en) | 2002-01-02 |
AU779280B2 (en) | 2005-01-13 |
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