WO2000005386A3 - Chorismate biosynthesis enzymes - Google Patents

Chorismate biosynthesis enzymes Download PDF

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Publication number
WO2000005386A3
WO2000005386A3 PCT/US1999/016352 US9916352W WO0005386A3 WO 2000005386 A3 WO2000005386 A3 WO 2000005386A3 US 9916352 W US9916352 W US 9916352W WO 0005386 A3 WO0005386 A3 WO 0005386A3
Authority
WO
WIPO (PCT)
Prior art keywords
biosynthesis enzymes
dahp synthetase
relates
chimeric gene
chorismate biosynthesis
Prior art date
Application number
PCT/US1999/016352
Other languages
French (fr)
Other versions
WO2000005386A2 (en
Inventor
Layo O Famodu
William D Hitz
Jonathan Edward Lightner
Original Assignee
Du Pont
Layo O Famodu
William D Hitz
Jonathan Edward Lightner
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Du Pont, Layo O Famodu, William D Hitz, Jonathan Edward Lightner filed Critical Du Pont
Priority to EP99937326A priority Critical patent/EP1098984A2/en
Priority to JP2000561332A priority patent/JP2002522024A/en
Priority to AU52187/99A priority patent/AU5218799A/en
Publication of WO2000005386A2 publication Critical patent/WO2000005386A2/en
Publication of WO2000005386A3 publication Critical patent/WO2000005386A3/en
Priority to US10/105,729 priority patent/US6911331B2/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8243—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
    • C12N15/8251—Amino acid content, e.g. synthetic storage proteins, altering amino acid biosynthesis
    • C12N15/8254—Tryptophan or lysine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8243—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
    • C12N15/8251—Amino acid content, e.g. synthetic storage proteins, altering amino acid biosynthesis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Plant Pathology (AREA)
  • Nutrition Science (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

This invention relates to an isolated nucleic acid fragment encoding a DAHP synthetase. The invention also relates to the construction of a chimeric gene encoding all or a portion of the DAHP synthetase, in sense or antisense orientation, wherein expression of the chimeric gene results in production of altered levels of the DAHP synthetase in a transformed host cell.
PCT/US1999/016352 1998-07-21 1999-07-20 Chorismate biosynthesis enzymes WO2000005386A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
EP99937326A EP1098984A2 (en) 1998-07-21 1999-07-20 Chorismate biosynthesis enzymes
JP2000561332A JP2002522024A (en) 1998-07-21 1999-07-20 Chorismate biosynthetic enzyme
AU52187/99A AU5218799A (en) 1998-07-21 1999-07-20 Chorismate biosynthesis enzymes
US10/105,729 US6911331B2 (en) 1998-07-21 2002-03-22 Chorismate biosynthesis enzymes

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US9361198P 1998-07-21 1998-07-21
US60/093,611 1998-07-21

Publications (2)

Publication Number Publication Date
WO2000005386A2 WO2000005386A2 (en) 2000-02-03
WO2000005386A3 true WO2000005386A3 (en) 2000-04-27

Family

ID=22239867

Family Applications (3)

Application Number Title Priority Date Filing Date
PCT/US1999/016352 WO2000005386A2 (en) 1998-07-21 1999-07-20 Chorismate biosynthesis enzymes
PCT/US1999/016354 WO2000005387A1 (en) 1998-07-21 1999-07-20 Chorismate biosynthesis enzymes
PCT/US1999/016353 WO2000005353A2 (en) 1998-07-21 1999-07-20 Chorismate synthase from plants

Family Applications After (2)

Application Number Title Priority Date Filing Date
PCT/US1999/016354 WO2000005387A1 (en) 1998-07-21 1999-07-20 Chorismate biosynthesis enzymes
PCT/US1999/016353 WO2000005353A2 (en) 1998-07-21 1999-07-20 Chorismate synthase from plants

Country Status (5)

Country Link
US (1) US20040064848A1 (en)
EP (2) EP1098984A2 (en)
JP (2) JP2002522024A (en)
AU (3) AU5218799A (en)
WO (3) WO2000005386A2 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU5779499A (en) * 1998-08-28 2000-03-21 Pioneer Hi-Bred International, Inc. Organelle targeting sequences
US6737237B1 (en) * 1999-05-04 2004-05-18 Apicomplexan Therapeutics, Llc Antimicrobial agents, diagnostic reagents, and vaccines based on unique Apicomplexan parasite components
US6465217B1 (en) 2000-07-05 2002-10-15 Paradigm Genetics, Inc. Methods and compositions for the modulation of chorismate synthase and chorismate mutase expression or activity in plants
CA2415382A1 (en) * 2000-07-07 2002-01-17 Basf Aktiengesellschaft Dehydroquinate dehydrase/shikimate dehydrogenase as a herbicide target
GB0100290D0 (en) * 2001-01-05 2001-02-14 Pantherix Ltd Assay
AU2008300579B2 (en) * 2007-09-18 2014-11-13 Basf Plant Science Gmbh Plants with increased yield
WO2012004795A1 (en) * 2010-07-06 2012-01-12 Yeda Research And Development Co. Ltd. Transgenic plants having altered dahp synthase activity

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0608722A1 (en) * 1993-01-29 1994-08-03 American Cyanamid Company Biological screens for detection of herbicides
WO1997026366A1 (en) * 1996-01-19 1997-07-24 Dekalb Genetics Corporation Anthranilate synthase gene and use thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5187071A (en) * 1988-07-15 1993-02-16 Fischer Randy S Method for the selective control of weeds, pests, and microbes
US5776736A (en) * 1992-12-21 1998-07-07 Purdue Research Foundation Deblocking the common pathway of aromatic amino acid synthesis
WO1998003661A2 (en) * 1996-07-19 1998-01-29 Arch Development Corporation Antimicrobial agents, diagnostic reagents, and vaccines based on unique apicomplexan parasite components
US6020159A (en) * 1996-09-24 2000-02-01 Smithkline Beecham Corporation 3-dehydroquinate synthase

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0608722A1 (en) * 1993-01-29 1994-08-03 American Cyanamid Company Biological screens for detection of herbicides
WO1997026366A1 (en) * 1996-01-19 1997-07-24 Dekalb Genetics Corporation Anthranilate synthase gene and use thereof

Non-Patent Citations (10)

* Cited by examiner, † Cited by third party
Title
BATZ O. ET AL.: "AC AF012864; O22407", EMBL DATABASE, Heidelberg, pages 1997 - 1998, XP002129966 *
DYER W. ET AL.: "A cDNA encoding 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase from Solanum tuberosum L.; AC P21357", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 265, 1990, pages 1608 - 1614, XP002129967 *
GORLACH J ET AL: "Differential expression of tomato ( Lycopersicon esculentum L.) genes encoding shikimate pathway isoenzymes. I. 3 - deoxy - D - arabino - heptulosonate 7 - phosphate synthase.", PLANT MOLECULAR BIOLOGY, (1993 NOV) 23 (4) 697-706., XP002121067 *
HERRMANN K.: "The shikimate pathway as an entry to aromatic secondary metabolism", PLANT PHYSIOLOGY, vol. 107, 1995, pages 7 - 12, XP002121069 *
JONES J D ET AL: "IMPAIRED WOUND INDUCTION OF 3-DEOXY-D-ARABINO-HEPTULOSONATE-7-PHOSPHATE ( DAHP ) SYNTHASE AND ALTERED STEM DEVELOPMENT IN TRANSGENIC POTATO PLANTS EXPRESSING A DAHP SYNTHASE ANTISENSE CONSTRUCT", PLANT PHYSIOLOGY, (AUG 1995) VOL. 108, NO. 4, PP. 1413-1421. ISSN: 0032-0889., XP002121068 *
SASAKI T. ET AL.: "AC AU68686", EMBL DATABASE, 7 June 1999 (1999-06-07), Heidelberg, XP002129970 *
SHOEMAKER R. ET AL.: "AC AI443687", EMBL DATBASE, 16 March 1999 (1999-03-16), Heidelberg, XP002129969 *
WALBOT V. ET AL.: "AC AI615213", EMBL DATABASE, 26 April 1999 (1999-04-26), Heidelberg, XP002129968 *
WALBOT V.: "Maize EST AC AI677182", EMBL DATABASE, 25 May 1999 (1999-05-25), Heidelberg, XP002121070 *
WIND J. ET AL.: "AC O24051; Y14797", EMBL DATABASE, 1 January 1998 (1998-01-01), Heidelberg, XP002129965 *

Also Published As

Publication number Publication date
EP1098984A2 (en) 2001-05-16
EP1098963A2 (en) 2001-05-16
AU5218799A (en) 2000-02-14
AU5113899A (en) 2000-02-14
JP2002522024A (en) 2002-07-23
WO2000005353A3 (en) 2000-05-04
WO2000005386A2 (en) 2000-02-03
AU5113999A (en) 2000-02-14
US20040064848A1 (en) 2004-04-01
WO2000005387A1 (en) 2000-02-03
WO2000005353A2 (en) 2000-02-03
JP2002521028A (en) 2002-07-16

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