UY30468A1 - Compuestos quimicos. - Google Patents
Compuestos quimicos.Info
- Publication number
- UY30468A1 UY30468A1 UY30468A UY30468A UY30468A1 UY 30468 A1 UY30468 A1 UY 30468A1 UY 30468 A UY30468 A UY 30468A UY 30468 A UY30468 A UY 30468A UY 30468 A1 UY30468 A1 UY 30468A1
- Authority
- UY
- Uruguay
- Prior art keywords
- chemical compounds
- conditions
- compounds
- dioxoalkenes
- dioxoalkanes
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 2
- 206010027654 Allergic conditions Diseases 0.000 abstract 1
- 206010020751 Hypersensitivity Diseases 0.000 abstract 1
- 208000029578 Muscle disease Diseases 0.000 abstract 1
- 208000021642 Muscular disease Diseases 0.000 abstract 1
- 208000026935 allergic disease Diseases 0.000 abstract 1
- 230000009610 hypersensitivity Effects 0.000 abstract 1
- 230000004968 inflammatory condition Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 238000011321 prophylaxis Methods 0.000 abstract 1
- 210000002460 smooth muscle Anatomy 0.000 abstract 1
- 238000011282 treatment Methods 0.000 abstract 1
Classifications
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/12—Ketones
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- C—CHEMISTRY; METALLURGY
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- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
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- C07C217/02—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C217/04—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C217/06—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted
- C07C217/14—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to a carbon atom of a six-membered aromatic ring
- C07C217/18—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to a carbon atom of a six-membered aromatic ring the six-membered aromatic ring or condensed ring system containing that ring being further substituted
- C07C217/22—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to a carbon atom of a six-membered aromatic ring the six-membered aromatic ring or condensed ring system containing that ring being further substituted by carbon atoms having at least two bonds to oxygen atoms
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- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
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- C07C255/56—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and doubly-bound oxygen atoms bound to the carbon skeleton
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- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
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- C07C45/455—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation with carboxylic acids or their derivatives
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- C—CHEMISTRY; METALLURGY
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- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
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- C07C45/673—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by change of size of the carbon skeleton
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- C—CHEMISTRY; METALLURGY
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- C—CHEMISTRY; METALLURGY
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- C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
- C07C45/72—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction of compounds containing >C = O groups with the same or other compounds containing >C = O groups
- C07C45/74—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction of compounds containing >C = O groups with the same or other compounds containing >C = O groups combined with dehydration
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- C—CHEMISTRY; METALLURGY
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- C07C49/04—Saturated compounds containing keto groups bound to acyclic carbon atoms
- C07C49/12—Ketones containing more than one keto group
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- C07C49/577—Unsaturated compounds containing keto groups bound to rings other than six-membered aromatic rings containing ether groups, groups, groups, or groups
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- C07C69/73—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
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- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
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- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
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- Hematology (AREA)
Abstract
Dioxoalcanos y dioxoalquenos susitutídos utiles para el tratamiento o profilaxis de la hipersensibilidad, desordenes de musculo liso, condiciones espasmodicas, condiciones alérgicas, condiciones inflamatorias y/o dolor, composiciones farmacéuticas que comprenden dichos compuestos y métodos de preparacion de los mismos.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
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GBGB0613518.0A GB0613518D0 (en) | 2006-07-06 | 2006-07-06 | Chemical compounds |
Publications (1)
Publication Number | Publication Date |
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UY30468A1 true UY30468A1 (es) | 2008-05-31 |
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UY30468A UY30468A1 (es) | 2006-07-06 | 2007-07-06 | Compuestos quimicos. |
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US (1) | US7589123B2 (es) |
EP (1) | EP2046311A2 (es) |
JP (1) | JP5397903B2 (es) |
CN (1) | CN101511350A (es) |
AR (1) | AR061955A1 (es) |
AU (1) | AU2007270951B2 (es) |
CA (1) | CA2660182A1 (es) |
CL (1) | CL2007001976A1 (es) |
GB (2) | GB0613518D0 (es) |
HK (1) | HK1114600A1 (es) |
MX (1) | MX2009000283A (es) |
PE (1) | PE20080274A1 (es) |
TW (1) | TW200819122A (es) |
UY (1) | UY30468A1 (es) |
WO (1) | WO2008003978A2 (es) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
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PT2049500E (pt) | 2006-07-06 | 2011-12-23 | Array Biopharma Inc | Ciclopenta[d]pirimidinas como inibidores da proteína quinase akt |
US8063050B2 (en) | 2006-07-06 | 2011-11-22 | Array Biopharma Inc. | Hydroxylated and methoxylated pyrimidyl cyclopentanes as AKT protein kinase inhibitors |
JP5231411B2 (ja) | 2006-07-06 | 2013-07-10 | アレイ バイオファーマ、インコーポレイテッド | Aktプロテインキナーゼ阻害剤としてのジヒドロチエノピリミジン |
CA2656566C (en) | 2006-07-06 | 2014-06-17 | Array Biopharma Inc. | Dihydrofuro pyrimidines as akt protein kinase inhibitors |
US9409886B2 (en) | 2007-07-05 | 2016-08-09 | Array Biopharma Inc. | Pyrimidyl cyclopentanes as AKT protein kinase inhibitors |
CN101918373B (zh) | 2007-07-05 | 2013-06-05 | 阵列生物制药公司 | 作为akt蛋白激酶抑制剂的嘧啶基环戊烷 |
US8846683B2 (en) | 2007-07-05 | 2014-09-30 | Array Biopharma, Inc. | Pyrimidyl cyclopentanes as Akt protein kinase inhibitors |
KR20150089099A (ko) | 2007-07-05 | 2015-08-04 | 어레이 바이오파마 인크. | Akt 단백질 키나제 억제제로서의 피리미딜 시클로펜탄 |
EP2247578B1 (en) | 2008-01-09 | 2013-05-22 | Array Biopharma, Inc. | Hydroxylated pyrimidyl cyclopentanes as akt protein kinase inhibitors |
ES2401685T3 (es) | 2008-01-09 | 2013-04-23 | Array Biopharma, Inc. | Pirimidil ciclopentano hidroxilado como inhibidor de la proteína quinasa AKT |
EP2385935A4 (en) * | 2009-01-12 | 2014-11-05 | Purapharm Company Ltd | COMPOUNDS AND APPLICATIONS THEREFOR FOR TREATING INFLAMMATION AND FOR MODULATING IMMUNE REACTIONS |
EP2694072B1 (en) | 2011-04-01 | 2017-11-29 | Genentech, Inc. | Combination of akt inhibitor compound and abiraterone for use in therapeutic treatments |
JP6147246B2 (ja) | 2011-04-01 | 2017-06-14 | ジェネンテック, インコーポレイテッド | Akt及びmek阻害剤化合物の組み合わせ、及び使用方法 |
KR101369882B1 (ko) * | 2012-01-17 | 2014-03-26 | 한국화학연구원 | (4-하이드록시-3-메톡시페닐)부테논 유도체 또는 이의 약학적으로 허용가능한 염을 유효성분으로 함유하는 천식 예방 또는 치료용 약학적 조성물 |
US8754084B2 (en) | 2012-03-27 | 2014-06-17 | The Board Of Trustees Of The University Of Illinois | Therapeutic methods and agents for treating myotonic dystrophy |
WO2014087331A2 (en) * | 2012-12-06 | 2014-06-12 | Mahesh Kandula | Compositions and methods for the treatment of epilepsy and neurologic diseases |
CA2956464C (en) | 2014-08-08 | 2023-05-09 | The Board Of Trustees Of The University Of Illinois | Bisamidinium-based inhibitors for the treatment of myotonic dystrophy |
US11135318B2 (en) * | 2016-06-29 | 2021-10-05 | The General Hospital Corporation | Half-curcuminoids as amyloid-beta PET imaging agents |
US11242326B2 (en) | 2017-08-25 | 2022-02-08 | The Board Of Trustees Of The University Of Illinois | Multivalent ligand for myotonic dystrophy |
CN115894241A (zh) * | 2022-10-17 | 2023-04-04 | 深圳凯联健康生物科技有限公司 | 咖啡活性酚、组合物及其在制备具有促进肠蠕动作用和/或缓解便秘作用的产品中的应用 |
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DE1133385B (de) * | 1960-04-14 | 1962-07-19 | Zyma Blaes A G Chem Fab | Verfahren zur Herstellung von 3-Pyrazyl-pyrazolderivaten |
US4649157A (en) * | 1986-03-28 | 1987-03-10 | G. D. Searle & Co. | Pharmaceutical compositions containing 5-phenyl-1,3-dioxoalkenyl compounds |
US4810716A (en) | 1986-04-11 | 1989-03-07 | Warner-Lambert Company | Diarylalkanoids having activity as lipoxygenase inhibitors |
WO1989008093A1 (en) | 1988-03-02 | 1989-09-08 | Terumo Kabushiki Kaisha | Catechol compounds, process for their preparation and pharmaceutical preparation containing same |
ZA941088B (en) * | 1993-02-19 | 1995-09-27 | Symphar Sa | Substituted ketophosphonates the processes for their preparation and pharmaceutical compositions containing them |
JP3376016B2 (ja) | 1993-05-31 | 2003-02-10 | 塩野義製薬株式会社 | カルバペネムの合成中間体の製造方法 |
US6518315B1 (en) * | 1997-10-21 | 2003-02-11 | The University Of Sydney | Medicinal uses of phenylaikanols and derivatives |
JP2003306438A (ja) | 2002-02-18 | 2003-10-28 | Shiseido Co Ltd | ケモカイン発現阻害剤 |
PL374970A1 (en) * | 2002-08-02 | 2005-11-14 | Argenta Discovery Limited | Substituted thienyl-hydroxamic acids as histone deacetylase inhibitors |
EP2565178A1 (en) * | 2002-10-03 | 2013-03-06 | Ono Pharmaceutical Co., Ltd. | LPA Receptor Antagonists |
AU2003275637A1 (en) | 2002-10-24 | 2004-05-13 | Wakamoto Pharmaceutical Co., Ltd. | Pyrazole-4-alkanoate derivatives inhibiting cyclooxygenase and 5-lipoxygenase |
GB0308318D0 (en) | 2003-04-10 | 2003-05-14 | Merck Sharp & Dohme | Therapeutic agents |
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2006
- 2006-07-06 GB GBGB0613518.0A patent/GB0613518D0/en not_active Ceased
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2007
- 2007-07-05 WO PCT/GB2007/002527 patent/WO2008003978A2/en active Application Filing
- 2007-07-05 US US11/773,952 patent/US7589123B2/en not_active Expired - Fee Related
- 2007-07-05 AR ARP070103007A patent/AR061955A1/es unknown
- 2007-07-05 TW TW096124462A patent/TW200819122A/zh unknown
- 2007-07-05 EP EP07733478A patent/EP2046311A2/en not_active Withdrawn
- 2007-07-05 JP JP2009517431A patent/JP5397903B2/ja not_active Expired - Fee Related
- 2007-07-05 PE PE2007000872A patent/PE20080274A1/es not_active Application Discontinuation
- 2007-07-05 CN CNA2007800255371A patent/CN101511350A/zh active Pending
- 2007-07-05 MX MX2009000283A patent/MX2009000283A/es active IP Right Grant
- 2007-07-05 CA CA002660182A patent/CA2660182A1/en not_active Abandoned
- 2007-07-05 CL CL200701976A patent/CL2007001976A1/es unknown
- 2007-07-05 GB GB0713117A patent/GB2440034B/en not_active Expired - Fee Related
- 2007-07-05 AU AU2007270951A patent/AU2007270951B2/en not_active Expired - Fee Related
- 2007-07-06 UY UY30468A patent/UY30468A1/es not_active Application Discontinuation
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2008
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Also Published As
Publication number | Publication date |
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AU2007270951A1 (en) | 2008-01-10 |
JP5397903B2 (ja) | 2014-01-22 |
TW200819122A (en) | 2008-05-01 |
WO2008003978A2 (en) | 2008-01-10 |
CN101511350A (zh) | 2009-08-19 |
EP2046311A2 (en) | 2009-04-15 |
CL2007001976A1 (es) | 2008-05-16 |
CA2660182A1 (en) | 2008-01-10 |
AR061955A1 (es) | 2008-08-10 |
WO2008003978A3 (en) | 2008-12-31 |
GB0713117D0 (en) | 2007-08-15 |
GB2440034B (en) | 2011-02-16 |
US20080045591A1 (en) | 2008-02-21 |
PE20080274A1 (es) | 2008-04-10 |
GB2440034A (en) | 2008-01-16 |
MX2009000283A (es) | 2009-01-26 |
JP2009544577A (ja) | 2009-12-17 |
US7589123B2 (en) | 2009-09-15 |
HK1114600A1 (en) | 2008-11-07 |
AU2007270951B2 (en) | 2013-04-11 |
GB0613518D0 (en) | 2006-08-16 |
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