UA109412C2 - 5-метил-n2-[4-(4-метилпіперазин-1-іл)феніл]-піримідин-2,4-діамін та його застосування в способі одержання сполуки - Google Patents

5-метил-n2-[4-(4-метилпіперазин-1-іл)феніл]-піримідин-2,4-діамін та його застосування в способі одержання сполуки Download PDF

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Publication number: UA109412C2
Authority: UA; Ukraine
Prior art keywords: mmol; mixture; filtered; concentrated; solid
Prior art date: 2005-11-01

Application number

UAA201203128A

Other languages

English (en)

Ukrainian (uk)

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2005-11-01

Filing date

2006-10-26

Publication date

2015-08-25

2006-10-26 Application filed filed Critical

2015-08-25 Publication of UA109412C2 publication Critical patent/UA109412C2/uk

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238000000034 method Methods 0.000 title claims description 32
238000002360 preparation method Methods 0.000 title description 20
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150000001875 compounds Chemical class 0.000 claims abstract description 398
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UAA201203128A 2005-11-01 2006-10-26 5-метил-n2-[4-(4-метилпіперазин-1-іл)феніл]-піримідин-2,4-діамін та його застосування в способі одержання сполуки UA109412C2 (uk)

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AU2011205485B2 (en) *	2010-01-13	2014-09-25	Glaxosmithkline Llc	Compounds and methods
AU2010363329A1 (en) *	2010-11-07	2013-05-09	Targegen, Inc.	Compositions and methods for treating myelofibrosis
CN103242240B (zh) *	2012-02-10	2016-01-06	上海温康化学研发有限公司	一种磺酰胺类化合物的中间体、其盐及其制备方法
CN103655566B (zh) *	2012-09-10	2016-12-21	杨子娇	化合物在制备防治青光眼病的药物中的用途
CN103664798A (zh) *	2012-09-20	2014-03-26	杨育新	一类治疗创伤性脑损伤疾病的化合物及其用途
CN103664799A (zh) *	2012-09-25	2014-03-26	杨子娇	一类治疗房角狭窄的化合物及其用途
CN103664907A (zh) *	2012-09-25	2014-03-26	杨子娇	一类治疗房角狭窄的化合物及其用途
CN103724331A (zh) *	2012-10-11	2014-04-16	韩冰	一类治疗脑性瘫痪的化合物及其用途
KR102334260B1 (ko) *	2013-03-14	2021-12-02	스미토모 다이니폰 파마 온콜로지, 인크.	Ｊａｋ2 및 ａｌｋ2 억제제 및 이들의 사용 방법
HUE040346T2 (hu) *	2013-12-11	2019-03-28	Biogen Ma Inc	Az onkológia, neurológia és immunológia területén a humán betegségek kezelésében hasznos biaril vegyületek
CN103992262B (zh) *	2014-06-12	2015-11-11	苏州明锐医药科技有限公司	塞瑞替尼及其中间体的制备方法
CN106188063A (zh) *	2015-05-08	2016-12-07	中国科学院上海药物研究所	用作Lp-PLA2抑制剂的双环类化合物、其制备方法及医药用途
CN108689949A (zh) *	2018-07-02	2018-10-23	湖南华腾制药有限公司	一种嘧啶类衍生物及其制备方法
CN110305140B (zh)	2019-07-30	2020-08-04	上海勋和医药科技有限公司	二氢吡咯并嘧啶类选择性jak2抑制剂
WO2021057882A1 (zh) *	2019-09-26	2021-04-01	贝达药业股份有限公司	Egfr抑制剂、组合物及其制备方法
TW202241440A (zh) *	2020-12-29	2022-11-01	大陸商上海岸闊醫藥科技有限公司	預防或治療抗腫瘤劑相關疾病或病症的方法
WO2022148317A1 (zh) *	2021-01-11	2022-07-14	广州市力鑫药业有限公司	2-氨基嘧啶类化合物及其药物组合物和应用
CN112920124B (zh) *	2021-01-29	2024-03-01	安徽医科大学	一种嘧啶-2,4-二胺类化合物及其制备方法与应用

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UA109412C2 (uk)	2015-08-25	5-метил-n2-[4-(4-метилпіперазин-1-іл)феніл]-піримідин-2,4-діамін та його застосування в способі одержання сполуки
RU2597364C2 (ru)	2016-09-10	Би-арил-мета-пиримидиновые ингибиторы киназ
US8604042B2 (en)	2013-12-10	Bi-aryl meta-pyrimidine inhibitors of kinases
US8133900B2 (en)	2012-03-13	Use of bi-aryl meta-pyrimidine inhibitors of kinases
AU2002312933B2 (en)	2007-12-06	CDK inhibiting pyrimidines, production thereof and their use as medicaments
KR101488467B1 (ko)	2015-01-30	Ｍａｐｋ／ｅｒｋ 키나아제 억제제
KR20070113288A (ko)	2007-11-28	피리미딘 화합물 및 사용 방법
HUE029264T2 (en)	2017-02-28	Pyrazolo-triazine derivatives are selective cyclin-dependent kinase inhibitors
TWI334868B (en)	2010-12-21	[1,2,4] triazoro [1,5-a] pyrimidine-2-ylurea derivative and use thereof
US6566357B1 (en)	2003-05-20	Spirocyclic-6,7-dihydro-5H-pyrazolo[1,2-a]pyrazol-1-ones which control inflammatory cytokines
AU2012230091B2 (en)	2015-04-23	Bi-aryl meta-pyrimidine inhibitors of kinases
MX2008005810A (en)	2008-09-26	Bi-aryl meta-pyrimidine inhibitors of kinases
US20040038971A1 (en)	2004-02-26	6,7-dihydro-5H-pyrazolo[1,2-a]pyrazol-1-ones which control inflammatory cytokines