SI1179533T1 - Salt of naphthyridine carboxylic acid derivative - Google Patents

Salt of naphthyridine carboxylic acid derivative

Info

Publication number
SI1179533T1
SI1179533T1 SI9830595T SI9830595T SI1179533T1 SI 1179533 T1 SI1179533 T1 SI 1179533T1 SI 9830595 T SI9830595 T SI 9830595T SI 9830595 T SI9830595 T SI 9830595T SI 1179533 T1 SI1179533 T1 SI 1179533T1
Authority
SI
Slovenia
Prior art keywords
salt
carboxylic acid
acid derivative
naphthyridine carboxylic
naphthyridine
Prior art date
Application number
SI9830595T
Other languages
English (en)
Slovenian (sl)
Inventor
Ae Ri Kim
Jin Hwa Lee
Ki Sook Park
Jong Ryoo Choi
Tae Hee Lee
Jay Hyok Chang
Do Hyun Nam
Hoon Choi
Original Assignee
Lg Life Sciences Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lg Life Sciences Ltd. filed Critical Lg Life Sciences Ltd.
Publication of SI1179533T1 publication Critical patent/SI1179533T1/

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4375Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having nitrogen as a ring heteroatom, e.g. quinolizines, naphthyridines, berberine, vincamine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/16Central respiratory analeptics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00Sulfonic acids; Halides, esters, or anhydrides thereof
    • C07C309/01Sulfonic acids
    • C07C309/02Sulfonic acids having sulfo groups bound to acyclic carbon atoms
    • C07C309/03Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
    • C07C309/04Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton containing only one sulfo group
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13Crystalline forms, e.g. polymorphs

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pulmonology (AREA)
  • Urology & Nephrology (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
SI9830595T 1997-03-21 1998-03-20 Salt of naphthyridine carboxylic acid derivative SI1179533T1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
KR19970009840 1997-03-21
EP01203507A EP1179533B1 (en) 1997-03-21 1998-03-20 Salt of naphthyridine carboxylic acid derivative
EP98908300A EP0981527B1 (en) 1997-03-21 1998-03-20 Salt of naphthyridine carboxylic acid derivative

Publications (1)

Publication Number Publication Date
SI1179533T1 true SI1179533T1 (en) 2004-04-30

Family

ID=19500439

Family Applications (2)

Application Number Title Priority Date Filing Date
SI9830595T SI1179533T1 (en) 1997-03-21 1998-03-20 Salt of naphthyridine carboxylic acid derivative
SI9830418T SI0981527T1 (en) 1997-03-21 1998-03-20 Salt of naphthyridine carboxylic acid derivative

Family Applications After (1)

Application Number Title Priority Date Filing Date
SI9830418T SI0981527T1 (en) 1997-03-21 1998-03-20 Salt of naphthyridine carboxylic acid derivative

Country Status (39)

Country Link
US (9) US7700617B2 ( )
EP (2) EP0981527B1 ( )
JP (3) JP3759962B2 ( )
KR (1) KR100266499B1 ( )
CN (1) CN1131229C ( )
AP (1) AP1331A ( )
AR (1) AR012125A1 ( )
AT (2) ATE257836T1 ( )
AU (1) AU726634B2 ( )
BG (1) BG63972B1 ( )
BR (1) BR9808290A ( )
CA (1) CA2283671C ( )
CZ (2) CZ288673B6 ( )
DE (2) DE69821147T2 ( )
DK (2) DK0981527T3 ( )
DZ (1) DZ2448A1 ( )
EA (1) EA001674B1 ( )
ES (2) ES2213669T3 ( )
HK (1) HK1026698A1 ( )
HU (2) HU227536B1 ( )
ID (1) ID22681A ( )
IL (2) IL131812A ( )
IN (1) IN188178B ( )
IS (2) IS2093B ( )
MA (1) MA24500A1 ( )
MY (1) MY137653A ( )
NO (1) NO312515B1 ( )
NZ (1) NZ337748A ( )
OA (1) OA11161A ( )
PE (1) PE67999A1 ( )
PL (1) PL191815B1 ( )
PT (2) PT981527E ( )
SA (1) SA98181055B1 ( )
SI (2) SI1179533T1 ( )
SK (1) SK284107B6 ( )
TR (1) TR199902313T2 ( )
UA (1) UA56218C2 ( )
WO (1) WO1998042705A1 ( )
ZA (1) ZA982335B ( )

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GB9820405D0 (en) * 1998-09-18 1998-11-11 Smithkline Beecham Plc Process
TR200102699T2 (tr) * 1999-03-19 2002-03-21 Knoll Gmbh Kronik mafsal bozukluĞunun (osteoarthritis) tedavisi
US6262071B1 (en) 1999-06-29 2001-07-17 Smithkline Beecham Corporation Methods of use of antimicrobial compounds against pathogenic amycoplasma bacteria
US6331550B1 (en) 1999-06-29 2001-12-18 Smithkline Beecham Corporation Methods of use of quinolone compounds against anaerobic pathogenic bacteria
US6803376B1 (en) 1999-06-29 2004-10-12 Smithkline Beecham Corporation Method of use of quinolone compounds against pneumococcal and haemophilus bacteria
CA2282066C (en) 1999-06-29 2010-09-07 Smithkline Beecham Corporation Methods of use of quinolone compounds against atypical upper respiratory pathogenic bacteria
GB9920919D0 (en) * 1999-09-03 1999-11-10 Sb Pharmco Inc Novel compound
GB9920917D0 (en) * 1999-09-03 1999-11-10 Sb Pharmco Inc Novel process
JP2001097863A (ja) * 1999-09-24 2001-04-10 Smithkline Beecham Corp 嫌気性病原菌に対するフルオロキノロン化合物の使用法
WO2001021176A1 (en) * 1999-09-22 2001-03-29 Smithkline Beecham Corporation Methods of use of fluoroquinolone compounds against bacteria
JP2001097891A (ja) * 1999-09-24 2001-04-10 Smithkline Beecham Corp 呼吸器系病原菌に対するフルオロキノロン化合物の使用法
GR1003520B (el) * 1999-09-22 2001-01-22 Smithkline Beecham Plc Μεθοδος χρησης ενωσεων φλουοροκινολονης εναντια σε νοσοκομειακα αρνητικα κατα gramμ παθογενων βακτηριδιων
JP2001097864A (ja) * 1999-09-24 2001-04-10 Smithkline Beecham Corp 呼吸管および尿路病原性細菌に対するフルオロキノリン化合物の使用方法
GR1003521B (el) * 1999-09-23 2001-01-22 Smithkline Beecham Plc Μεθοδοι χρησεως ενωσεων φλουοροκινολονης εναντια κατα gram θετικων παθογονων βακτηριδιων
KR20010091379A (ko) * 2000-03-15 2001-10-23 성재갑 7-(4-아미노메틸-3-옥심)피롤리딘 치환체를 갖는 퀴놀린카르복실산 유도체의 신규 제조방법
SI1412078T1 (sl) 2001-08-02 2009-04-30 Lg Life Sciences Ltd Lg Twin T Postopki za pripravo amino-zaščitenih derivatov 4-aminometilen-pirolidin-3-ona, gemifloksacina ali njegove soli
MXPA04005179A (es) * 2001-11-30 2004-08-11 Lg Life Sciences Ltd Un metodo para tratar infecciones bacterianas usando gemifloxacina o una sal de la misma y una antibiotico de (-lactama.
KR100517638B1 (ko) 2002-04-08 2005-09-28 주식회사 엘지생명과학 게미플록사신 산염의 새로운 제조방법
AR043880A1 (es) * 2003-04-22 2005-08-17 Solvay Pharm Gmbh Mesilato acido de 4-(4.trans-hidroxiciclohexil) amino-2-fenil-7h-pirrolo (2,3-d) pirimidina y sus formas polimorfas
US7834027B2 (en) 2005-06-15 2010-11-16 Hetero Drugs Limited Gemifloxacin process and polymorphs
KR20130128483A (ko) * 2006-03-07 2013-11-26 욱크하트 리미티드 벤조퀴놀리진-2-카르복실산의 프로드러그
WO2010001408A2 (en) * 2008-06-06 2010-01-07 Matrix Laboratories Ltd. Novel polymorphic forms of gemifloxacin mesylate
WO2010146594A1 (en) * 2009-06-16 2010-12-23 Hetero Research Foundation Novel polymorphs of gemifloxacin mesylate
EP2491921A1 (en) 2011-02-25 2012-08-29 Deva Holding Anonim Sirketi Conservation of anhydrous form of gemifloxacin
RS56556B1 (sr) * 2012-02-27 2018-02-28 Bristol Myers Squibb Co N- (5s, 6s, 9r) - 5 -amino- 6 - (2, 3 - difluorofenil) -6, 7, 8, 9 - tetrahidro - 5h - ciklohepta [b]piridin-9 -il- 4 - (2 - okso-2, 3 - dihidro - 1h- imidazo [4, 5 -b]piridin - 1 - il) piperidin - 1 - karboksilat, hemisulfatna so
CZ2016104A3 (cs) * 2016-02-24 2017-09-06 Zentiva, K.S. Krystalické modifikace solí methyl (3Z)-3-{[(4-{methyl[(4-methylpiperazin-1-yl)acetyl]amino}fenyl)amino](fenyl)methyliden}-2-oxo-2,3-dihydro-1H-indol-6-karboxylátu a způsoby jejich přípravy

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ES512969A0 (es) 1981-06-11 1983-02-16 Warner Lambert Co "un procedimiento para preparar sales de compuestos de naftiridina y quinoleina".
IN162769B ( ) 1984-11-13 1988-07-09 Kyorin Seiyaku Kk
NZ222047A (en) 1986-10-08 1991-01-29 Bristol Myers Co Quinoline - or naphthyridine - carboxylic acid anti-bacterial agents
JPH01100165A (ja) 1987-10-13 1989-04-18 Shionogi & Co Ltd オキシムまたはヒドロキシアミン誘導体系抗菌剤
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PL166381B1 (pl) 1989-08-16 1995-05-31 Pfizer Sposób wytwarzania nowych podstawionych kwasów 7-azabicyklochinolonokarboksylowych PL PL PL PL
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GB9820405D0 (en) 1998-09-18 1998-11-11 Smithkline Beecham Plc Process

Also Published As

Publication number Publication date
NO994595D0 (no) 1999-09-21
US20140187576A1 (en) 2014-07-03
CZ328299A3 (cs) 2000-02-16
CN1251101A (zh) 2000-04-19
IS7952A (is) 2005-07-21
CA2283671A1 (en) 1998-10-01
IS2093B (is) 2006-04-12
MA24500A1 (fr) 1998-10-01
EP0981527B1 (en) 2003-05-07
ID22681A (id) 1999-12-09
IS5181A (is) 1999-09-14
US20090182006A1 (en) 2009-07-16
SA98181055B1 (ar) 2006-10-11
JP2004002413A (ja) 2004-01-08
HU0600401D0 (en) 2006-07-28
HK1026698A1 (en) 2000-12-22
CZ288715B6 (cs) 2001-08-15
KR19980080504A (ko) 1998-11-25
JP4781614B2 (ja) 2011-09-28
PT981527E (pt) 2003-09-30
UA56218C2 (uk) 2003-05-15
EA199900855A1 (ru) 2000-04-24
BG103750A (en) 2000-06-30
HUP0000728A2 (hu) 2000-09-28
EP1179533B1 (en) 2004-01-14
US20170253588A1 (en) 2017-09-07
MY137653A (en) 2009-02-27
NZ337748A (en) 2001-03-30
HU227536B1 (en) 2011-08-29
US20150291585A1 (en) 2015-10-15
DE69821147D1 (de) 2004-02-19
US20110312987A1 (en) 2011-12-22
PE67999A1 (es) 1999-09-30
DE69821147T2 (de) 2004-11-11
EP1179533A2 (en) 2002-02-13
ZA982335B (en) 1999-11-23
DE69814378D1 (de) 2003-06-12
DE69814378T2 (de) 2004-02-26
EP1179533A3 (en) 2002-03-20
HUP0000728A3 (en) 2002-12-28
SI0981527T1 (en) 2003-10-31
IS2095B (is) 2006-04-12
AR012125A1 (es) 2000-09-27
WO1998042705A1 (en) 1998-10-01
OA11161A (en) 2003-04-25
BR9808290A (pt) 2000-05-16
DK0981527T3 (da) 2003-09-01
US20160264569A1 (en) 2016-09-15
US20100240694A1 (en) 2010-09-23
ES2198697T3 (es) 2004-02-01
CA2283671C (en) 2003-09-16
NO312515B1 (no) 2002-05-21
DZ2448A1 (fr) 2003-01-11
JP2000510484A (ja) 2000-08-15
AU6636698A (en) 1998-10-20
EA001674B1 (ru) 2001-06-25
US20080039488A1 (en) 2008-02-14
US7700617B2 (en) 2010-04-20
AU726634B2 (en) 2000-11-16
CZ288673B6 (cs) 2001-08-15
IN188178B ( ) 2002-08-31
KR100266499B1 (ko) 2000-12-01
PL191815B1 (pl) 2006-07-31
US20130065917A1 (en) 2013-03-14
JP2009051851A (ja) 2009-03-12
SK123699A3 (en) 2000-08-14
JP3759962B2 (ja) 2006-03-29
EP0981527A1 (en) 2000-03-01
ATE257836T1 (de) 2004-01-15
DK1179533T3 (da) 2004-05-03
TR199902313T2 (xx) 1999-12-21
AP9901649A0 (en) 1999-09-30
BG63972B1 (bg) 2003-08-29
ATE239724T1 (de) 2003-05-15
NO994595L (no) 1999-09-21
ES2213669T3 (es) 2004-09-01
SK284107B6 (sk) 2004-09-08
IL131812A0 (en) 2001-03-19
IL131812A (en) 2006-04-10
AP1331A (en) 2004-11-26
PL335812A1 (en) 2000-05-22
CN1131229C (zh) 2003-12-17
PT1179533E (pt) 2004-05-31
HU225412B1 (en) 2006-11-28
HUP0600401A3 (en) 2010-05-28

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