SG11201906632WA - Bioprocess vessels with integrated pump - Google Patents
Bioprocess vessels with integrated pumpInfo
- Publication number
- SG11201906632WA SG11201906632WA SG11201906632WA SG11201906632WA SG11201906632WA SG 11201906632W A SG11201906632W A SG 11201906632WA SG 11201906632W A SG11201906632W A SG 11201906632WA SG 11201906632W A SG11201906632W A SG 11201906632WA SG 11201906632W A SG11201906632W A SG 11201906632WA
- Authority
- SG
- Singapore
- Prior art keywords
- international
- pump
- substantially rigid
- flexible bag
- secured
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/05—Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
- A61J1/10—Bag-type containers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F27/00—Mixers with rotary stirring devices in fixed receptacles; Kneaders
- B01F27/60—Mixers with rotary stirring devices in fixed receptacles; Kneaders with stirrers rotating about a horizontal or inclined axis
- B01F27/61—Mixers with rotary stirring devices in fixed receptacles; Kneaders with stirrers rotating about a horizontal or inclined axis about an inclined axis
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F27/00—Mixers with rotary stirring devices in fixed receptacles; Kneaders
- B01F27/60—Mixers with rotary stirring devices in fixed receptacles; Kneaders with stirrers rotating about a horizontal or inclined axis
- B01F27/71—Mixers with rotary stirring devices in fixed receptacles; Kneaders with stirrers rotating about a horizontal or inclined axis with propellers
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F27/00—Mixers with rotary stirring devices in fixed receptacles; Kneaders
- B01F27/80—Mixers with rotary stirring devices in fixed receptacles; Kneaders with stirrers rotating about a substantially vertical axis
- B01F27/91—Mixers with rotary stirring devices in fixed receptacles; Kneaders with stirrers rotating about a substantially vertical axis with propellers
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
- B01F35/50—Mixing receptacles
- B01F35/513—Flexible receptacles, e.g. bags supported by rigid containers
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
- B01F35/75—Discharge mechanisms
- B01F35/754—Discharge mechanisms characterised by the means for discharging the components from the mixer
- B01F35/7544—Discharge mechanisms characterised by the means for discharging the components from the mixer using pumps
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M23/00—Constructional details, e.g. recesses, hinges
- C12M23/02—Form or structure of the vessel
- C12M23/14—Bags
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M23/00—Constructional details, e.g. recesses, hinges
- C12M23/46—Means for fastening
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M27/00—Means for mixing, agitating or circulating fluids in the vessel
- C12M27/02—Stirrer or mobile mixing elements
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
- C12M29/10—Perfusion
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
- F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
- F04B43/00—Machines, pumps, or pumping installations having flexible working members
- F04B43/02—Machines, pumps, or pumping installations having flexible working members having plate-like flexible members, e.g. diaphragms
- F04B43/06—Pumps having fluid drive
- F04B43/073—Pumps having fluid drive the actuating fluid being controlled by at least one valve
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
- F04D—NON-POSITIVE-DISPLACEMENT PUMPS
- F04D1/00—Radial-flow pumps, e.g. centrifugal pumps; Helico-centrifugal pumps
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
- F04D—NON-POSITIVE-DISPLACEMENT PUMPS
- F04D29/00—Details, component parts, or accessories
- F04D29/40—Casings; Connections of working fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/1475—Inlet or outlet ports
- A61J1/1481—Inlet or outlet ports with connection retaining means, e.g. thread or snap-fit
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F2101/00—Mixing characterised by the nature of the mixed materials or by the application field
- B01F2101/44—Mixing of ingredients for microbiology, enzymology, in vitro culture or genetic manipulation
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
- F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
- F04B43/00—Machines, pumps, or pumping installations having flexible working members
- F04B43/02—Machines, pumps, or pumping installations having flexible working members having plate-like flexible members, e.g. diaphragms
- F04B43/06—Pumps having fluid drive
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Sustainable Development (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Clinical Laboratory Science (AREA)
- Mechanical Engineering (AREA)
- Hematology (AREA)
- Reciprocating Pumps (AREA)
- External Artificial Organs (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)
- Structures Of Non-Positive Displacement Pumps (AREA)
Abstract
W O 20 18/ 14439 1 Al (12) INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (43) International Publication Date 09 August 2018 (09.08.2018) WIP0 I PCT onion °nolo Homo mil mu Imo oimIE (10) International Publication Number WO 2018/144391 Al 6 (51) International Patent Classification: A61M 5/148 (2006.01) A61M 5/142 (2006.01) A61J 1/10 (2006.01) A61M 5/145 (2006.01) A61M 5/14 (2006.01) (21) International Application Number: PCT/US2018/015777 (22) International Filing Date: 29 January 2018 (29.01.2018) (25) Filing Language: English (26) Publication Language: English (30) Priority Data: 62/452,783 31 January 2017 (31.01.2017) US (71) Applicant: ALPHINITY, LLC [US/US]; 1771 S. Sutro Terrace, Carson City, Nevada 89706 (US). (72) Inventor: GAGNE, Michael C.; 1771 S. Sutro Terrace, Carson City, Nevada 89706 (US). (74) Agent: DAVIDSON, Michael S.; VISTA IP LAW GROUP LLP, 100 Spectrum Center Drive, Suite 900, Irvine, California 92618 (US). (81) Designated States (unless otherwise indicated, for every kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (84) Designated States (unless otherwise indicated, for every kind of regional protection available): ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). Published: — with international search report (Art. 21(3)) (54) Title: BIOPROCESS VESSELS WITH INTEGRATED PUMP (57) : A bioprocess vessel includes a flexible bag or substantially rigid 52 2 container that defines an interior volume and having a bottom surface, the bot- tom surface being open or containing an aperture therein for the passage of flu- id. A pump is secured to the bottom surface of the flexible bag or substantially rigid container. In some embodiments is secured directly to the flexible bag or substantially rigid container. In other embodiments, the pump is secured indi- rectly the flexible bag or substantially rigid container using, for example, a port that extends through the aperture on the bottom surface. The port or flanged surface may also be integrated into the pump, which is secured to the vessel. An optional mixing adaptor may be provided inside the interior volume of the flexible bag or substantially rigid container and at least partially covers the inlet that leads to the pump. 46 41 46 46 50 FIG. 2A
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201762452783P | 2017-01-31 | 2017-01-31 | |
PCT/US2018/015777 WO2018144391A1 (en) | 2017-01-31 | 2018-01-29 | Bioprocess vessels with integrated pump |
Publications (1)
Publication Number | Publication Date |
---|---|
SG11201906632WA true SG11201906632WA (en) | 2019-08-27 |
Family
ID=63041010
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11201906632WA SG11201906632WA (en) | 2017-01-31 | 2018-01-29 | Bioprocess vessels with integrated pump |
Country Status (6)
Country | Link |
---|---|
US (2) | US11331248B2 (en) |
EP (1) | EP3576814A4 (en) |
KR (1) | KR102547782B1 (en) |
SG (1) | SG11201906632WA (en) |
TW (1) | TWI762566B (en) |
WO (1) | WO2018144391A1 (en) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US11708555B2 (en) * | 2019-05-30 | 2023-07-25 | Global Life Sciences Solutions Usa Llc | System, method and apparatus for draining a bioreactor vessel |
US11535421B2 (en) * | 2019-12-30 | 2022-12-27 | Global Life Sciences Solutions Usa Llc | System and method for packaging a bioprocessing bag and associated components, and packaging for a bioprocessing bag |
EP4100649A4 (en) * | 2020-02-04 | 2023-07-05 | Alphinity USA, Inc. | Pump and combination pump/mixer device |
WO2023220613A1 (en) * | 2022-05-11 | 2023-11-16 | Aquasyn, Llc | Single-use fluid container with return ports |
WO2024073408A1 (en) * | 2022-09-28 | 2024-04-04 | Aquasyn, Llc | Single-use flexible bag with sump |
Family Cites Families (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA1110137A (en) * | 1976-05-24 | 1981-10-06 | Ingemar H. Lundquist | Intravenous liquid pumping system and method |
US4983102A (en) | 1988-10-14 | 1991-01-08 | Swain Danny C | Self-enclosed filter pumping system |
US5676531A (en) * | 1996-03-21 | 1997-10-14 | Pulsafeeder, Inc. | Autoclavable pump head assembly |
US5836482A (en) * | 1997-04-04 | 1998-11-17 | Ophardt; Hermann | Automated fluid dispenser |
DE19921693A1 (en) | 1999-05-12 | 2000-11-16 | Boehringer Ingelheim Pharma | Pharmaceutical composition for treating respiratory disorders, e.g. asthma, comprises combination of anticholinergic and beta-mimetic agents having synergistic bronchospasmolytic activity and reduced side-effects |
CN1260343C (en) | 2002-01-31 | 2006-06-21 | 赛宇细胞科技股份有限公司 | Cell culture device |
US7033823B2 (en) | 2002-01-31 | 2006-04-25 | Cesco Bioengineering, Inc. | Cell-cultivating device |
US20090130704A1 (en) * | 2003-11-13 | 2009-05-21 | Gyure Dale C | Novel bioreactor |
US7972058B2 (en) * | 2005-03-16 | 2011-07-05 | Pendotech | Apparatus and method for mixing with a diaphragm pump |
WO2009122310A2 (en) * | 2008-03-19 | 2009-10-08 | Sartorius Stedim Biotech Gmbh | Disposable mixing vessel |
US20110236970A1 (en) | 2008-08-01 | 2011-09-29 | Smart Biosystems Aps | Chamber of a bioreactor platform |
US8235067B2 (en) | 2009-05-15 | 2012-08-07 | Alphabio, Inc. | Encapsulated valve system |
CN107349671A (en) | 2010-08-25 | 2017-11-17 | 瑞繁技术有限责任公司 | Fluid filter system |
US20120130341A1 (en) | 2010-11-19 | 2012-05-24 | Carefusion 303, Inc. | Combined iv bag and pump system and method |
KR20160048871A (en) | 2013-08-29 | 2016-05-04 | 알피니티, 엘엘씨 | Method and device for overmolding uv-curable material over polymer inserts |
EP3055663B1 (en) * | 2013-10-08 | 2021-12-01 | Sartorius Stedim Biotech GmbH | Extraction device, method and use for obtaining a sample of a medium to be extracted |
DE102013221706A1 (en) * | 2013-10-25 | 2015-04-30 | Robert Bosch Gmbh | Method for the metered dispensing of liquid ingredients from a tubular bag and means for carrying out the method |
WO2015066229A2 (en) | 2013-10-30 | 2015-05-07 | Alphinity, Llc | Fluid monitoring device with disposable inner liner with sensor integration |
SG11201605760PA (en) | 2014-01-17 | 2016-08-30 | Alphinity Llc | Fluid monitoring assembly with sensor functionality |
SG11201704870VA (en) | 2014-12-19 | 2017-07-28 | Alphinity Llc | Encapsulated system for pressurized fluid processes |
JP6351113B2 (en) | 2015-01-29 | 2018-07-04 | 藤森工業株式会社 | Shaking culture apparatus and culture method using the same |
TWI744230B (en) * | 2015-04-22 | 2021-11-01 | 美商伯克利之光生命科技公司 | Microfluidic device and method of culturing biological cells in the microfluidic device |
EP3298355B8 (en) | 2015-05-19 | 2021-06-30 | Repligen Corporation | Fluid monitoring assembly with flow sensor |
JP6955769B2 (en) | 2015-09-15 | 2021-10-27 | アルフィニティ, エルエルシーAlphinity, Llc | Flexible tube management system for pharmaceuticals, bioprocesses, and food / dairy products |
WO2017059370A1 (en) | 2015-10-01 | 2017-04-06 | Alphinity, Llc | Valve assembly with directional flow path |
US20190101154A1 (en) | 2016-03-23 | 2019-04-04 | Alphinity, Llc | Encapsulated ball joint system for pressurized fluid processes |
-
2018
- 2018-01-29 EP EP18747897.9A patent/EP3576814A4/en active Pending
- 2018-01-29 KR KR1020197025228A patent/KR102547782B1/en active IP Right Grant
- 2018-01-29 SG SG11201906632WA patent/SG11201906632WA/en unknown
- 2018-01-29 WO PCT/US2018/015777 patent/WO2018144391A1/en unknown
- 2018-01-29 US US16/480,070 patent/US11331248B2/en active Active
- 2018-01-31 TW TW107103443A patent/TWI762566B/en active
-
2022
- 2022-04-13 US US17/720,241 patent/US11666508B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
TWI762566B (en) | 2022-05-01 |
US11666508B2 (en) | 2023-06-06 |
KR20230096140A (en) | 2023-06-29 |
KR20190112766A (en) | 2019-10-07 |
EP3576814A1 (en) | 2019-12-11 |
US20190367859A1 (en) | 2019-12-05 |
WO2018144391A1 (en) | 2018-08-09 |
US20220233402A1 (en) | 2022-07-28 |
TW201835324A (en) | 2018-10-01 |
US20230293388A1 (en) | 2023-09-21 |
EP3576814A4 (en) | 2020-02-19 |
KR102547782B1 (en) | 2023-06-23 |
US11331248B2 (en) | 2022-05-17 |
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