SE431452B - Forfarande for framstellning av pyrazinkarboxamider - Google Patents

Forfarande for framstellning av pyrazinkarboxamider

Info

Publication number: SE431452B
Authority: SE; Sweden
Prior art keywords: procedure; preparation; carboxamides; pyrazine; pyrazine carboxamides
Prior art date: 1975-12-15

Application number

SE7613289A

Other languages

English (en)

Other versions

SE7613289L (sv

Inventor

Jr E J Cragoe

O W Woltersdorf

C N Habecker

Original Assignee

Merck & Co Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1975-12-15

Filing date

1976-11-26

Publication date

1984-02-06

1976-11-26 Application filed by Merck & Co Inc filed Critical Merck & Co Inc

1977-06-16 Publication of SE7613289L publication Critical patent/SE7613289L/sv

1984-02-06 Publication of SE431452B publication Critical patent/SE431452B/sv

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D241/24—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D241/26—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with nitrogen atoms directly attached to ring carbon atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Diabetes (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Hematology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

SE7613289A 1975-12-15 1976-11-26 Forfarande for framstellning av pyrazinkarboxamider SE431452B (sv)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US64080375A	1975-12-15	1975-12-15

Publications (2)

Publication Number	Publication Date
SE7613289L SE7613289L (sv)	1977-06-16
SE431452B true SE431452B (sv)	1984-02-06

Family

ID=24569755

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SE7613289A SE431452B (sv)	1975-12-15	1976-11-26	Forfarande for framstellning av pyrazinkarboxamider

Country Status (14)

Country	Link
US (1)	US4085211A (sv)
JP (1)	JPS52106877A (sv)
AU (1)	AU511429B2 (sv)
BE (1)	BE849379A (sv)
CH (1)	CH630369A5 (sv)
DE (1)	DE2656374A1 (sv)
DK (1)	DK531476A (sv)
ES (2)	ES454160A1 (sv)
FR (1)	FR2335226A1 (sv)
GB (1)	GB1527297A (sv)
HU (1)	HU175504B (sv)
NL (1)	NL7613276A (sv)
SE (1)	SE431452B (sv)
ZA (1)	ZA767431B (sv)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4208413A (en) *	1977-03-04	1980-06-17	Merck & Co., Inc.	N-Pyrazinecarbonyl-N'-alkoxycarbonyl and N',N"-bis(alkoxycarbonyl)guanidines and processes for preparing same
US4163781A (en) *	1978-04-17	1979-08-07	Merck & Co., Inc.	3-Amino-N-[(phosphonoamino)iminomethyl]-6-halopyrazinecarboxamide compounds, compositions and methods of use
EP0009054A1 (en) *	1978-09-19	1980-04-02	Merck & Co. Inc.	N-Pyrazinecarbonyl-N'-substituted-sulfamoyl-guanidine and processes for preparing same
US4272537A (en) *	1980-07-02	1981-06-09	Merck & Co., Inc.	3-Amino-5-substituted-6-halo-N-(4,4-disubstituted-6-substituted-1,3,5-triazin-2-yl)-2-pyrazinecarboxamides
US4277602A (en) *	1980-07-02	1981-07-07	Merck & Co., Inc.	3-Amino-5-substituted-6-halo-N-(3,4-dihydro-6-substituted-1,3,5-truazin-2-yl)2-pyrazinecarboxamides
FI820266L (fi) *	1981-02-02	1982-08-03	Ici Plc	Alkanolaminderivater
US4594349A (en) *	1982-01-04	1986-06-10	Beyer Jr Karl H	Hyperuretic agents
JPS62291361A (ja) *	1986-06-09	1987-12-18	株式会社ブリヂストン	床支持装置
JPS6342741U (sv) *	1986-09-04	1988-03-22
GB8810933D0 (en) *	1987-05-26	1988-06-15	Ici America Inc	Heterocyclic compounds
GB8810934D0 (en) *	1987-05-26	1988-06-15	Ici America Inc	Amides
GB8812342D0 (en) *	1988-05-25	1988-06-29	Ici America Inc	Bicyclic compounds
GB8812343D0 (en) *	1988-05-25	1988-06-29	Ici America Inc	Amino compounds
JPH02101937U (sv) *	1989-01-31	1990-08-14
AUPP646498A0 (en) *	1998-10-12	1998-11-05	Australian National University, The	A method of modulating ion channel functional activity
US6858614B2 (en) *	2002-02-19	2005-02-22	Parion Sciences, Inc.	Phenolic guanidine sodium channel blockers
US6858615B2 (en) *	2002-02-19	2005-02-22	Parion Sciences, Inc.	Phenyl guanidine sodium channel blockers
US6903105B2 (en) *	2003-02-19	2005-06-07	Parion Sciences, Inc.	Sodium channel blockers
US20050090505A1 (en) *	2003-08-18	2005-04-28	Johnson Michael R.	Methods of reducing risk of infection from pathogens
US7745442B2 (en)	2003-08-20	2010-06-29	Parion Sciences, Inc.	Methods of reducing risk of infection from pathogens
US20090253714A1 (en) *	2003-08-20	2009-10-08	Johnson Michael R	Methods of reducing risk of infection from pathogens
WO2006023617A2 (en) *	2004-08-18	2006-03-02	Johnson Michael R	Cyclic amide & ester pyrazinoylguanidine sodium channel blockers
US20070021439A1 (en) *	2005-07-25	2007-01-25	Parion Sciences, Inc.	Methods of reducing risk of infection from pathogens with soluble amide and ester pyrazinoylguanidine sodium channel blockers
GB0526244D0 (en) *	2005-12-22	2006-02-01	Novartis Ag	Organic compounds
AR069637A1 (es)	2007-12-10	2010-02-10	Novartis Ag	Derivados de pirazinas
DE102008053024B4 (de)	2008-10-24	2015-04-30	RUHR-UNIVERSITäT BOCHUM	Verwendung von Amilorid-Derivaten zur Bekämpfung von Insekten und Milben
AR086745A1 (es)	2011-06-27	2014-01-22	Parion Sciences Inc	3,5-diamino-6-cloro-n-(n-(4-(4-(2-(hexil(2,3,4,5,6-pentahidroxihexil)amino)etoxi)fenil)butil)carbamimidoil)pirazina-2-carboxamida
BR112015014178A2 (pt)	2012-12-17	2017-07-11	Parion Sciences Inc	compostos de 3,5-diamino-6-cloro-n-(n-(4-fenilbutil)carbamimidoil) pirazina-2- carboxamida
ES2619954T3 (es)	2012-12-17	2017-06-27	Parion Sciences, Inc.	Derivados de cloropiracinocarboxamida útiles para el tratamiento de enfermedades favorecidas por una hidratación mucosa insuficiente
US9102633B2 (en)	2013-12-13	2015-08-11	Parion Sciences, Inc.	Arylalkyl- and aryloxyalkyl-substituted epithelial sodium channel blocking compounds
WO2016043230A1 (ja) *	2014-09-18	2016-03-24	日産化学工業株式会社	液晶配向剤、液晶配向膜、及び液晶表示素子

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NL299931A (sv) *	1962-10-30
NL299929A (sv) *	1962-10-30

1976
- 1976-09-13 US US05/722,442 patent/US4085211A/en not_active Expired - Lifetime
- 1976-11-25 DK DK531476A patent/DK531476A/da not_active Application Discontinuation
- 1976-11-26 SE SE7613289A patent/SE431452B/sv not_active IP Right Cessation
- 1976-11-29 NL NL7613276A patent/NL7613276A/xx not_active Application Discontinuation
- 1976-12-02 AU AU20181/76A patent/AU511429B2/en not_active Expired
- 1976-12-10 ES ES454160A patent/ES454160A1/es not_active Expired
- 1976-12-13 GB GB51940/76A patent/GB1527297A/en not_active Expired
- 1976-12-13 HU HU76ME2034A patent/HU175504B/hu unknown
- 1976-12-13 FR FR7637459A patent/FR2335226A1/fr active Granted
- 1976-12-13 DE DE19762656374 patent/DE2656374A1/de active Granted
- 1976-12-13 CH CH1566076A patent/CH630369A5/de not_active IP Right Cessation
- 1976-12-14 BE BE173235A patent/BE849379A/xx not_active IP Right Cessation
- 1976-12-14 ZA ZA00767431A patent/ZA767431B/xx unknown
- 1976-12-15 JP JP14988976A patent/JPS52106877A/ja active Granted
1978
- 1978-01-03 ES ES465742A patent/ES465742A1/es not_active Expired

Also Published As

Publication number	Publication date
ES454160A1 (es)	1978-03-01
DK531476A (da)	1977-06-16
BE849379A (fr)	1977-06-14
ES465742A1 (es)	1978-10-01
FR2335226A1 (fr)	1977-07-15
GB1527297A (en)	1978-10-04
DE2656374C2 (sv)	1989-08-10
CH630369A5 (de)	1982-06-15
AU2018176A (en)	1978-06-08
NL7613276A (nl)	1977-06-17
US4085211A (en)	1978-04-18
FR2335226B1 (sv)	1979-03-09
ZA767431B (en)	1978-07-26
HU175504B (hu)	1980-08-28
JPS6238350B2 (sv)	1987-08-17
AU511429B2 (en)	1980-08-21
SE7613289L (sv)	1977-06-16
DE2656374A1 (de)	1977-06-16
JPS52106877A (en)	1977-09-07

Legal Events

Date

Code

Title

Description

1995-01-31

NUG

Patent has lapsed

Ref document number: 7613289-3

Effective date: 19900706

Format of ref document f/p: F

Publication	Publication Date	Title
SE431452B (sv)	1984-02-06	Forfarande for framstellning av pyrazinkarboxamider
SE433208B (sv)	1984-05-14	Forfarande for framstellning av fenoletrar
SE7603791L (sv)	1976-10-01	Forfarande for framstellning av 17 alfa-ester-21-halogenpregnaner
SE7605139L (sv)	1976-11-08	Forfarande for framstellning av vattenupptagande cellulosaetrar
SE430336B (sv)	1983-11-07	Forbettrat forfarande for framstellning av amoxicillinfrihydrat
SE433610B (sv)	1984-06-04	Forfarande for framstellning av aromatiska uretaner
SE433937B (sv)	1984-06-25	Forfarande for framstellning av penicillinestrar
SE426065B (sv)	1982-12-06	Forfarande for framstellning av nikotinsyraamid
SE7611280L (sv)	1977-04-24	Forfarande for framstellning av 3-hydroxi-3-cefemestersulfoxider
SE7609281L (sv)	1977-02-24	Forfarande for framstellning av finkornig fast cyanurklorid
NO146058C (no)	1982-07-28	Analogifremgangsmaate for fremstilling av substituerte benzamider
NO139555C (no)	1979-04-04	Fremgangsmaate for fremstilling av fosgen
SE7607717L (sv)	1977-01-09	Analogiforfarande for framstellning av l-pyroglutamyl-l-prolinamid
SE432763B (sv)	1984-04-16	Forfarande for framstellning av nya homoftalimider
SE7606116L (sv)	1976-12-03	Forfarande for framstellning av 3-fenoxidbensaldehyder
SE7604781L (sv)	1976-12-05	Forfarande for framstellning av diarylhydroxibutylaminer
SE435716B (sv)	1984-10-15	Forfarande for framstellning av nya penicilliner
SE7604669L (sv)	1976-10-24	Forfarande for framstellning av estrar av tiokarbamidsyror
SE404186B (sv)	1978-09-25	Forfarande for framstellning av cyklopropanolderivat
SE7600847L (sv)	1976-07-28	Nytt forfarande for framstellning av 8-bromtienotriazolo-1,4-diazepiner
SE7610637L (sv)	1977-03-27	Forfarande for framstellning av 2-alkylindaner
SE446726B (sv)	1986-10-06	Forfarande for framstellning av 16-metoxiprostaglandiner
SE7604940L (sv)	1976-10-30	Forfarande for framstellning av sulfamylbensoesyror
SE7607026L (sv)	1976-12-20	Forfarande for framstellning av 5-alkylpikolinsyra
SE7605427L (sv)	1976-11-13	Forfarande for framstellning av klorcyan