PT89956A - Processo para a preparacao de acidos 1-ciclopropil-quinolonocarboxilicos e seus derivados - Google Patents

Processo para a preparacao de acidos 1-ciclopropil-quinolonocarboxilicos e seus derivados

Info

Publication number
PT89956A
PT89956A PT89956A PT8995689A PT89956A PT 89956 A PT89956 A PT 89956A PT 89956 A PT89956 A PT 89956A PT 8995689 A PT8995689 A PT 8995689A PT 89956 A PT89956 A PT 89956A
Authority
PT
Portugal
Prior art keywords
quinolonocarboxylic
cyclopropyl
derivatives
acids
preparation
Prior art date
Application number
PT89956A
Other languages
English (en)
Inventor
Uwe Petersen
Michael Schriewer
Klaus Grohe
Andreas Krebs
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of PT89956A publication Critical patent/PT89956A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
PT89956A 1988-03-11 1989-03-09 Processo para a preparacao de acidos 1-ciclopropil-quinolonocarboxilicos e seus derivados PT89956A (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3808118A DE3808118A1 (de) 1988-03-11 1988-03-11 Verfahren zur herstellung von 1-cyclopropyl-chinoloncarbonsaeuren und deren derivaten

Publications (1)

Publication Number Publication Date
PT89956A true PT89956A (pt) 1989-11-10

Family

ID=6349471

Family Applications (1)

Application Number Title Priority Date Filing Date
PT89956A PT89956A (pt) 1988-03-11 1989-03-09 Processo para a preparacao de acidos 1-ciclopropil-quinolonocarboxilicos e seus derivados

Country Status (8)

Country Link
EP (1) EP0332930A2 (pt)
JP (1) JPH01268679A (pt)
KR (1) KR890014489A (pt)
CN (1) CN1037335A (pt)
DE (1) DE3808118A1 (pt)
FI (1) FI891123A (pt)
IL (1) IL89535A0 (pt)
PT (1) PT89956A (pt)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUT67395A (en) * 1993-07-13 1995-04-28 Somfai Method for the n-cyclopropylation of primary and secondary aromatic amines
DE69831506T2 (de) * 1997-12-22 2006-06-29 Pharmacia & Upjohn Co. Llc, Kalamazoo 4-hydroxychinolin-3-carboxamide und hydrazide als antivirale wirkstoffe
US20100074949A1 (en) 2008-08-13 2010-03-25 William Rowe Pharmaceutical composition and administration thereof
NZ587551A (en) 2004-06-24 2012-01-12 Vertex Pharma 5-Amino-phenol derivatives such as 5-amino-2,4-di-tert-butyl-phenol
US8354427B2 (en) 2004-06-24 2013-01-15 Vertex Pharmaceutical Incorporated Modulators of ATP-binding cassette transporters
CN1305849C (zh) * 2004-12-29 2007-03-21 江苏正大天晴药业股份有限公司 3－甲氨基哌啶及其盐的制备方法
CN100457737C (zh) * 2005-04-05 2009-02-04 中国人民解放军军事医学科学院毒物药物研究所 喹啉酰胺衍生物、其制备方法和用途
SI3219705T1 (sl) 2005-12-28 2020-08-31 Vertex Pharmaceuticals Incorporated Farmacevtski sestavki amorfne oblike N-(2,4-bis(1,1-dimetiletil)-5- hidroksifenil)-1,4-dihidro-4-oksokinolin-3-karboksamid
PL2383271T3 (pl) 2006-03-13 2013-12-31 Kyorin Seiyaku Kk Aminochinolony jako inhibitory GSK-3
AU2010221990B2 (en) 2009-03-11 2015-06-04 Kyorin Pharmaceutical Co., Ltd. 7-cycloalkylaminoquinolones as GSK-3 inhibitors
RU2543714C2 (ru) 2009-03-20 2015-03-10 Вертекс Фармасьютикалз Инкорпорейтед Способ получения модуляторов регулятора трансмембранной проводимости кистозного фиброза
US8802700B2 (en) 2010-12-10 2014-08-12 Vertex Pharmaceuticals Incorporated Modulators of ATP-Binding Cassette transporters
BR112014021090B1 (pt) 2012-02-27 2023-01-24 Vertex Pharmaceuticals Incorporated Composição farmacêutica e uso de n-[2,4-bis(1,1-dimetiletil)-5-hidróxifenil]-1,4-di-hidro-4-oxoquinolina3-carboxamida na preparação da mesma
RU2749213C2 (ru) 2014-10-07 2021-06-07 Вертекс Фармасьютикалз Инкорпорейтед Сокристаллы модуляторов регулятора трансмембранной проводимости при кистозном фиброзе
CN107602465A (zh) * 2016-07-12 2018-01-19 重庆大学 一种喹诺酮类衍生物及其应用

Also Published As

Publication number Publication date
IL89535A0 (en) 1989-09-10
FI891123A0 (fi) 1989-03-09
KR890014489A (ko) 1989-10-24
EP0332930A2 (de) 1989-09-20
JPH01268679A (ja) 1989-10-26
DE3808118A1 (de) 1989-09-21
FI891123A (fi) 1989-09-12
CN1037335A (zh) 1989-11-22

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Legal Events

Date Code Title Description
FC3A Refusal

Effective date: 19940422