PE20000121A1 - Determinacion de anormalidad en el crecimiento celular - Google Patents

Determinacion de anormalidad en el crecimiento celular

Info

Publication number
PE20000121A1
PE20000121A1 PE1998000991A PE00099198A PE20000121A1 PE 20000121 A1 PE20000121 A1 PE 20000121A1 PE 1998000991 A PE1998000991 A PE 1998000991A PE 00099198 A PE00099198 A PE 00099198A PE 20000121 A1 PE20000121 A1 PE 20000121A1
Authority
PE
Peru
Prior art keywords
sample
mcm7
abnormality
polypeptide
cells
Prior art date
Application number
PE1998000991A
Other languages
English (en)
Inventor
Ronald Alfred Laskey
Gareth Haydn Williams
Nicholas Coleman
Original Assignee
Cancer Res Campaign Tech
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9722217.8A external-priority patent/GB9722217D0/en
Priority claimed from GBGB9724134.3A external-priority patent/GB9724134D0/en
Priority claimed from GBGB9804156.9A external-priority patent/GB9804156D0/en
Priority claimed from GBGB9810560.4A external-priority patent/GB9810560D0/en
Priority claimed from GBGB9817075.6A external-priority patent/GB9817075D0/en
Application filed by Cancer Res Campaign Tech filed Critical Cancer Res Campaign Tech
Publication of PE20000121A1 publication Critical patent/PE20000121A1/es

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407—Specifically defined cancers
    • G01N33/57411—Specifically defined cancers of cervix
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
    • G01N33/57496—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites involving intracellular compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Cell Biology (AREA)
  • Hematology (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Oncology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Hospice & Palliative Care (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)
  • Measuring And Recording Apparatus For Diagnosis (AREA)
  • Electrotherapy Devices (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Peptides Or Proteins (AREA)
  • Eye Examination Apparatus (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Liquid Crystal Substances (AREA)

Abstract

SE REFIERE A MOLECULAS DE UNION ESPECIFICAS (ANTICUERPOS) DIRIGIDAS CONTRA POLIPEPTIDOS PARTICULARES DEL COMPLEJO DE PREINICIO DE LA REPLICACION DE ADN TALES COMO Cdc6, MCM2, MCM3, MCM4, MCM5, MCM6, MCM7, QUINASA Cdc7, Dbf4, FOSFATASA Cdc14, Cdc45, MCM10, LAS QUE SON MAS EFECTIVAS PARA MARCAR LA ANORMALIDAD EN EL CRECIMIENTO CELULAR. TAMBIEN SE REFIERE A UN METODO PARA DETERMINAR, EVALUAR O DIAGNOSTICAR LA PRESENCIA O AUSENCIA DE PROLIFERACION ANORMAL DE CELULAS O ANORMALIDAD EN EL CRECIMIENTO CELULAR EN UNA MUESTRA DE TEJIDO, CELULAS O FLUIDOS DEL PULMON, MAMAS, COLON, PROSTATA, ESTOMAGO, PIEL, ESOFAGO, VEJIGA; LA MUESTRA PUEDE SER FRESCA O CONGELADA, NO ENCONTRANDOSE FIJA EN FORMALINA NI INCRUSTADA EN PARAFINA; LA MUESTRA SE PROVEE DE FLUIDO (SANGRE O ORINA) TOMADO DEL INDIVIDUO, QUE COMPRENDE DETECTAR EN LA MUESTRA UN POLIPEPTIDO O PLURALIDAD DE POLIPEPTIDOS AL PONER EN CONTACTO LA MUESTRA CON MOLECULAS DE UNION ESPECIFICO; CUANDO EL POLIPEPTIDO ES MCM7 LA MUESTRA ES SOMETIDA A RECUPERACION DE ANTIGENOS POR COCCION A PRESION O AUTOCLAVE
PE1998000991A 1997-10-21 1998-10-21 Determinacion de anormalidad en el crecimiento celular PE20000121A1 (es)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GBGB9722217.8A GB9722217D0 (en) 1997-10-21 1997-10-21 Determination of cellular growth abnormality
GBGB9724134.3A GB9724134D0 (en) 1997-11-14 1997-11-14 Determination of cellular growth abnormality
GBGB9804156.9A GB9804156D0 (en) 1998-02-26 1998-02-26 Determination of cellular growth abnormality
GBGB9810560.4A GB9810560D0 (en) 1998-05-15 1998-05-15 Determination of cellular growth abnormality
GBGB9817075.6A GB9817075D0 (en) 1998-08-05 1998-08-05 Determination of cellular growth abnormality

Publications (1)

Publication Number Publication Date
PE20000121A1 true PE20000121A1 (es) 2000-02-17

Family

ID=27517431

Family Applications (1)

Application Number Title Priority Date Filing Date
PE1998000991A PE20000121A1 (es) 1997-10-21 1998-10-21 Determinacion de anormalidad en el crecimiento celular

Country Status (23)

Country Link
EP (1) EP1025444B1 (es)
JP (2) JP2000511291A (es)
CN (1) CN1282422A (es)
AT (1) ATE290213T1 (es)
AU (1) AU751754B2 (es)
BR (1) BR9813127A (es)
CA (1) CA2305872C (es)
CO (1) CO5080817A1 (es)
DE (1) DE69829198T2 (es)
DK (1) DK1025444T3 (es)
ES (1) ES2239407T3 (es)
GB (1) GB2332515B (es)
HU (1) HUP0004134A2 (es)
IL (1) IL135602A0 (es)
IS (1) IS5456A (es)
MA (1) MA26557A1 (es)
NO (1) NO20002044L (es)
NZ (1) NZ503996A (es)
PE (1) PE20000121A1 (es)
PL (1) PL340057A1 (es)
PT (1) PT1025444E (es)
SK (1) SK5592000A3 (es)
WO (1) WO1999021014A1 (es)

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US6361954B1 (en) 1996-05-02 2002-03-26 Cold Spring Harbor Laboratory Methods of immunoassay for human CDC6
GB0018140D0 (en) * 2000-07-24 2000-09-13 Medical Res Council Screening for abnormalities
DE10063179A1 (de) * 2000-12-18 2002-06-20 Bayer Ag Verfahren zur spezifischen Detektion von Tumorzellen und ihren Vorstufen in Gebärmutterhalsabstrichen durch simultane Messung von mindestens zwei verschiedenen molekularen Markern
DE10063112A1 (de) 2000-12-18 2002-06-20 Bayer Ag Verfahren zur Erhöhung der klinischen Spezifität bei der Detektion von Tumoren und ihren Vorstufen durch simultane Messung von mindestens zwei verschiedenen molekularen Markern
EP1373896A2 (en) 2001-03-12 2004-01-02 MonoGen, Inc. Cell-based detection and differentiation of disease states
EP1369694A1 (en) 2002-04-09 2003-12-10 MTM Laboratories AG Method for discrimination of metaplasias from neoplastic or preneoplastic lesions
EP2311978A1 (en) * 2002-08-20 2011-04-20 Millennium Pharmaceuticals, Inc. Compositions, kits, and methods for identification, assessment, prevention, and therapy of cervical cancer
EP1422526A1 (en) 2002-10-28 2004-05-26 MTM Laboratories AG Method for improved diagnosis of dysplasias
US20070015154A1 (en) * 2003-02-14 2007-01-18 Smithkline Beecham Corporation Differentially expressed nucleic acids that correlate with ksp expression
US7361460B2 (en) 2003-04-11 2008-04-22 Digene Corporation Approach to molecular diagnosis of human papillomavirus-related diseases
EP1688503A4 (en) * 2003-10-20 2007-10-31 Sysmex Corp METHOD FOR THE TREATMENT OF CELLS
CN1957256B (zh) * 2004-03-24 2013-01-02 三路影像公司 用于子宫颈疾病检测的方法和组合物
US7595380B2 (en) * 2005-04-27 2009-09-29 Tripath Imaging, Inc. Monoclonal antibodies and methods for their use in the detection of cervical disease
GB0518877D0 (en) * 2005-09-15 2005-10-26 Medical Res Council Markers and methods
US7632498B2 (en) 2005-12-19 2009-12-15 Tripath Imaging, Inc. MCM6 and MCM7 monoclonal antibodies and methods for their use in the detection of cervical disease
ES2545119T3 (es) 2006-01-05 2015-09-08 The Ohio State University Research Foundation Métodos basados en microARN y composiciones para el diagnóstico y el tratamiento de cánceres sólidos
US7985584B2 (en) 2006-03-20 2011-07-26 The Ohio State University Research Foundation MicroRNA fingerprints during human megakaryocytopoiesis
DE102006020852A1 (de) 2006-05-04 2007-11-15 Robert Bosch Gmbh Gasdruckbehälter für gasbetriebene Kraftfahrzeuge
CN101835902B (zh) 2007-08-03 2014-03-26 俄亥俄州立大学研究基金会 编码ncrna的超保守区域
GB0811567D0 (en) * 2008-06-24 2008-07-30 Cytosystems Ltd Assay
AU2010321555B2 (en) 2009-11-23 2015-10-15 The Ohio State University Materials and methods useful for affecting tumor cell growth, migration and invasion
GB0921873D0 (en) * 2009-12-15 2010-01-27 Cytosystems Ltd Assay
CA2816603A1 (en) 2010-11-12 2012-05-18 The Ohio State University Research Foundation Materials and methods related to microrna-21, mismatch repair, and colorectal cancer
AU2011329066B2 (en) 2010-11-15 2017-03-09 The Ohio State University Research Foundation Controlled release mucoadhesive systems
WO2012090479A1 (en) * 2010-12-28 2012-07-05 Oncotherapy Science, Inc. Mcm7 as a target gene for cancer therapy and diagnosis
CA2852066A1 (en) 2011-10-14 2013-04-18 The Ohio State University Methods and materials related to ovarian cancer
AU2012352265B2 (en) 2011-12-13 2017-02-16 Ohio State Innovation Foundation Methods and compositions related to miR-21 and miR-29a, exosome inhibition, and cancer metastasis
EP2800821B1 (en) * 2012-01-05 2016-11-16 Centre National de la Recherche Scientifique (CNRS) Signature for the diagnosis of lung cancer aggressiveness
EP2804960A4 (en) 2012-01-20 2015-08-19 Univ Ohio State BREAST CANCER BIOMARK SIGNATURES FOR INVASIVITY AND FORECAST
US11306364B2 (en) 2012-02-18 2022-04-19 Duke University TERT promoter mutations in gliomas and a subset of tumors
KR101832948B1 (ko) * 2013-02-18 2018-02-28 듀크 유니버시티 신경교종 및 종양의 서브세트 내 tert 프로모터 돌연변이
GB201412731D0 (en) * 2014-07-17 2014-09-03 Immunocore Ltd & Adaptimmune Ltd Peptides
EP3295173A1 (en) * 2015-05-10 2018-03-21 Ventana Medical Systems, Inc. Compositions and methods for simultaneous inactivation of alkaline phosphatase and peroxidase enzymes during automated multiplex tissue staining assays
ES2911415T3 (es) 2015-06-08 2022-05-19 Arquer Diagnostics Ltd Métodos y kits
US11519916B2 (en) 2015-06-08 2022-12-06 Arquer Diagnostics Limited Methods for analysing a urine sample
GB201509907D0 (en) * 2015-06-08 2015-07-22 Urosens Ltd Antibodies
GB201511196D0 (en) 2015-06-25 2015-08-12 Cytosystems Ltd Monoclonal antibodies
JP6245299B2 (ja) * 2016-04-27 2017-12-13 バクスアルタ ゲーエムベーハー 組換え安定細胞クローン、その産生およびその使用
CN106636343B (zh) * 2016-11-04 2021-03-19 深圳大学 一种检测口腔癌的标志物及其试剂盒
GB201820867D0 (en) * 2018-12-20 2019-02-06 Arquer Diagnostics Ltd Detection method
CN115453108A (zh) * 2019-12-11 2022-12-09 广东菲鹏生物有限公司 用于免疫诊断试剂中固相载体的封闭阶段处理剂及应用和产品

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DK144485A (da) * 1984-03-30 1985-10-01 Syntex Inc Monoklonale antistoffer
US5851821A (en) * 1996-05-02 1998-12-22 Cold Spring Harbor Laboratory DNA Replication-regulating genes
EP0812594A1 (en) * 1996-06-13 1997-12-17 BOEHRINGER INGELHEIM INTERNATIONAL GmbH Compounds that interfere with DNA replication in rapidly proliferating cells for use in cancer therapy and methods for screening for such compounds
US5858683A (en) * 1996-08-30 1999-01-12 Matritech, Inc. Methods and compositions for the detection of cervical cancer

Also Published As

Publication number Publication date
AU751754B2 (en) 2002-08-29
CA2305872C (en) 2008-02-19
BR9813127A (pt) 2000-08-15
CO5080817A1 (es) 2001-09-25
MA26557A1 (fr) 2004-12-20
AU9550298A (en) 1999-05-10
GB9823069D0 (en) 1998-12-16
NO20002044D0 (no) 2000-04-18
DE69829198T2 (de) 2006-01-12
DK1025444T3 (da) 2005-06-27
WO1999021014A1 (en) 1999-04-29
JP2000511291A (ja) 2000-08-29
JP3774196B2 (ja) 2006-05-10
NZ503996A (en) 2002-04-26
PL340057A1 (en) 2001-01-15
EP1025444B1 (en) 2005-03-02
HUP0004134A2 (en) 2001-03-28
EP1025444A1 (en) 2000-08-09
DE69829198D1 (de) 2005-04-07
IS5456A (is) 2000-04-17
SK5592000A3 (en) 2000-10-09
PT1025444E (pt) 2005-07-29
CN1282422A (zh) 2001-01-31
GB2332515A (en) 1999-06-23
CA2305872A1 (en) 1999-04-29
IL135602A0 (en) 2001-05-20
GB2332515B (en) 1999-12-15
ATE290213T1 (de) 2005-03-15
ES2239407T3 (es) 2005-09-16
NO20002044L (no) 2000-06-07
JP2003240786A (ja) 2003-08-27

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