NO991688L - Administrerbare sammensetninger og fremgangsmÕter til magnetisk resonansavbildning - Google Patents
Administrerbare sammensetninger og fremgangsmÕter til magnetisk resonansavbildningInfo
- Publication number
- NO991688L NO991688L NO991688A NO991688A NO991688L NO 991688 L NO991688 L NO 991688L NO 991688 A NO991688 A NO 991688A NO 991688 A NO991688 A NO 991688A NO 991688 L NO991688 L NO 991688L
- Authority
- NO
- Norway
- Prior art keywords
- compositions
- methods
- magnetic resonance
- resonance imaging
- manageable
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 5
- 238000002595 magnetic resonance imaging Methods 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 2
- 238000009472 formulation Methods 0.000 abstract 2
- 239000007789 gas Substances 0.000 abstract 2
- 239000002872 contrast media Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
- A61K49/18—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes
- A61K49/1806—Suspensions, emulsions, colloids, dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/22—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations
- A61K49/222—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
- A61K49/223—Microbubbles, hollow microspheres, free gas bubbles, gas microspheres
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Radiology & Medical Imaging (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Dispersion Chemistry (AREA)
- Physics & Mathematics (AREA)
- Acoustics & Sound (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Magnetic Resonance Imaging Apparatus (AREA)
- Medicinal Preparation (AREA)
- Soft Magnetic Materials (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP97810563 | 1997-08-12 | ||
PCT/IB1998/001227 WO1999007415A1 (en) | 1997-08-12 | 1998-08-11 | Administrable compositions and methods for magnetic resonance imaging |
Publications (3)
Publication Number | Publication Date |
---|---|
NO991688D0 NO991688D0 (no) | 1999-04-09 |
NO991688L true NO991688L (no) | 1999-06-09 |
NO313865B1 NO313865B1 (no) | 2002-12-16 |
Family
ID=8230338
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO19991688A NO313865B1 (no) | 1997-08-12 | 1999-04-09 | Mikrovesikler, vandig dispersjon inneholdende disse, fremgangsmÕte for fremstilling av et kontrastmiddel,kontrastmidler samt et sett av reagenser |
Country Status (12)
Country | Link |
---|---|
US (1) | US6042809A (no) |
EP (1) | EP0968000B1 (no) |
JP (1) | JP4317270B2 (no) |
CN (1) | CN1103605C (no) |
AT (1) | ATE252916T1 (no) |
AU (1) | AU726115C (no) |
CA (1) | CA2268324C (no) |
DE (1) | DE69819309T2 (no) |
ES (1) | ES2209167T3 (no) |
IL (1) | IL129173A (no) |
NO (1) | NO313865B1 (no) |
WO (1) | WO1999007415A1 (no) |
Families Citing this family (41)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5922304A (en) * | 1989-12-22 | 1999-07-13 | Imarx Pharmaceutical Corp. | Gaseous precursor filled microspheres as magnetic resonance imaging contrast agents |
BR9711082A (pt) * | 1996-03-29 | 2000-01-11 | Lawrence Berkeley National Lab | Realce de rmn emri na presença de gases mopbres hiperpolarizados. |
WO1999047940A1 (en) | 1998-03-18 | 1999-09-23 | Magnetic Imaging Technologies Incorporated | MR METHODS FOR IMAGING PULMONARY AND CARDIAC VASCULATURE AND EVALUATING BLOOD FLOW USING DISSOLVED POLARIZED 129Xe |
US6423387B1 (en) | 1998-06-17 | 2002-07-23 | Medi-Physics, Inc. | Resilient containers for hyperpolarized gases and associated methods |
CA2336191C (en) | 1998-06-17 | 2008-12-16 | Medi-Physics, Inc. | Hyperpolarized gas transport devices and associated transport method |
US6128918A (en) * | 1998-07-30 | 2000-10-10 | Medi-Physics, Inc. | Containers for hyperpolarized gases and associated methods |
US6159444A (en) * | 1998-09-11 | 2000-12-12 | The Regents Of The University Of California | NMR/MRI with hyperpolarized gas and high Tc SQUID |
EP1118009A1 (en) * | 1998-09-28 | 2001-07-25 | Nycomed Imaging As | Method of magnetic resonance imaging |
US6286319B1 (en) | 1998-09-30 | 2001-09-11 | Medi-Physics, Inc. | Meted hyperpolarized noble gas dispensing methods and associated devices |
US6523356B2 (en) | 1998-09-30 | 2003-02-25 | Medi-Physics, Inc. | Meted hyperpolarized noble gas dispensing methods and associated devices |
US6237363B1 (en) | 1998-09-30 | 2001-05-29 | Medi-Physics, Inc. | Hyperpolarized noble gas extraction methods masking methods and associated transport containers |
US6284222B1 (en) | 1998-11-03 | 2001-09-04 | Medi--Physics, Inc. | Hyperpolarized helium-3 microbubble gas entrapment methods |
WO2000050914A1 (en) | 1999-02-23 | 2000-08-31 | Medi-Physics, Inc. | Portable system for monitoring the polarization level of a hyperpolarized gas during transport |
US6295834B1 (en) | 1999-06-30 | 2001-10-02 | Medi-Physics, Inc. | NMR polarization monitoring coils, hyperpolarizers with same, and methods for determining the polarization level of accumulated hyperpolarized noble gases during production |
US6308705B1 (en) * | 1999-12-21 | 2001-10-30 | Siemens Aktiengesellschaft | Integrated lung therapy method |
JP2003526437A (ja) | 2000-03-13 | 2003-09-09 | メディ−フィジックス・インコーポレイテッド | ガス状過分極129Xeの直接注射を使用する診断処置並びに関連するシステムおよび生成物 |
US20030165431A1 (en) * | 2000-07-13 | 2003-09-04 | The Regents Of The University Of California | Method for detecting macromolecular conformational change and binding information |
US7061237B2 (en) * | 2000-07-13 | 2006-06-13 | The Regents Of The University Of California | Remote NMR/MRI detection of laser polarized gases |
EP1324690A1 (en) | 2000-07-13 | 2003-07-09 | Medi-Physics, Inc. | DIAGNOSTIC PROCEDURES USING ?129 XE SPECTROSCOPY CHARACTERISTIC CHEMICAL SHIFT TO DETECT PATHOLOGY i IN VIVO /i |
US6652833B2 (en) * | 2000-07-13 | 2003-11-25 | The Regents Of The University Of California | Functionalized active-nucleus complex sensor |
US7179450B2 (en) | 2001-09-20 | 2007-02-20 | Medi-Physics, Inc. | Methods for in vivo evaluation of pulmonary physiology and/or function using NMR signals of polarized Xe |
CA2418229A1 (en) * | 2002-05-16 | 2003-11-16 | Rohan Dharmakumar | Microbubble construct for sensitivity enhanced mr manometry |
NO20022960D0 (no) | 2002-06-19 | 2002-06-19 | Medinnova Sf | Apparat og metode for intubasjonsovervåkning |
GB0218868D0 (en) | 2002-08-14 | 2002-09-25 | Nasir Muhammed A | Improved airway management device |
US20040167400A1 (en) * | 2002-11-27 | 2004-08-26 | Accuimage Diagnostics Corp. | Method and apparatus for improving a virtual colonoscopy and A CT angiography |
US20050025710A1 (en) * | 2003-07-29 | 2005-02-03 | Michel Schneider | Reconstitutable formulation and aqueous suspension of gas-filled microvesicles for diagnostic imaging |
DE102005026604A1 (de) * | 2005-06-09 | 2006-12-14 | Membrana Gmbh | Verfahren zum Lösen von Gasen mit kurzlebigen physikalischen Eigenschaften in einer Flüssigkeit |
US8377419B2 (en) * | 2005-09-28 | 2013-02-19 | The President And Fellows Of Harvard College | Hyperpolarized solid materials with long spin relaxation times for use as imaging agents in magnetic resonance imaging |
AU2006326596A1 (en) * | 2005-12-10 | 2007-06-21 | The President And Fellows Of Harvard College | In situ hyperpolarization of imaging agents |
US20090252686A1 (en) * | 2006-01-11 | 2009-10-08 | President And Fellows Of Harvard College | Ex Vivo Hyperpolarization of Imaging Agents |
US8703102B2 (en) | 2008-04-04 | 2014-04-22 | Millikelvin Technologies Llc | Systems and methods for producing hyperpolarized materials and mixtures thereof |
WO2007136439A2 (en) | 2006-02-21 | 2007-11-29 | Avrum Belzer | Hyperpolarization methods, systems and compositions |
GB0811856D0 (en) * | 2008-06-27 | 2008-07-30 | Ucl Business Plc | Magnetic microbubbles, methods of preparing them and their uses |
US20100092390A1 (en) * | 2008-10-09 | 2010-04-15 | President And Fellows Of Harvard College | Methods for Making Particles Having Long Spin-Lattice Relaxation Times |
JP2013180956A (ja) * | 2012-02-29 | 2013-09-12 | Sunstar Engineering Inc | 殺菌剤組成物 |
US20140288411A1 (en) * | 2013-03-12 | 2014-09-25 | The Regents Of The University Of California | Gas vesicle magnetic resonance imaging contrast agents and methods of using the same |
CN103815907B (zh) * | 2014-03-04 | 2016-04-06 | 合肥工业大学 | 用于人体呼吸***检测成像的成像气体及其储气装置 |
CN103807598B (zh) * | 2014-03-04 | 2016-06-01 | 合肥工业大学 | 一种储存成像气体的储气装置 |
US11350909B2 (en) | 2018-04-17 | 2022-06-07 | California Institute Of Technology | Cross amplitude modulation ultrasound pulse sequence |
JP7313856B2 (ja) * | 2019-03-27 | 2023-07-25 | 日本液炭株式会社 | キセノンウルトラファインバブル発生剤 |
CN111110657A (zh) * | 2020-02-14 | 2020-05-08 | 徐州医科大学 | 可双模成像及靶向治疗乳腺癌的纳米微球及其制备方法 |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5922304A (en) * | 1989-12-22 | 1999-07-13 | Imarx Pharmaceutical Corp. | Gaseous precursor filled microspheres as magnetic resonance imaging contrast agents |
US5585112A (en) * | 1989-12-22 | 1996-12-17 | Imarx Pharmaceutical Corp. | Method of preparing gas and gaseous precursor-filled microspheres |
IN172208B (no) * | 1990-04-02 | 1993-05-01 | Sint Sa | |
AU636481B2 (en) * | 1990-05-18 | 1993-04-29 | Bracco International B.V. | Polymeric gas or air filled microballoons usable as suspensions in liquid carriers for ultrasonic echography |
US5785983A (en) * | 1991-05-23 | 1998-07-28 | Euroresearch Srl | Non-porous collagen sheet for therapeutic use, and the method and apparatus for preparing it |
IL104084A (en) * | 1992-01-24 | 1996-09-12 | Bracco Int Bv | Sustainable aqueous suspensions of pressure-resistant and gas-filled blisters, their preparation, and contrast agents containing them |
US5545396A (en) * | 1994-04-08 | 1996-08-13 | The Research Foundation Of State University Of New York | Magnetic resonance imaging using hyperpolarized noble gases |
US5617860A (en) * | 1995-06-07 | 1997-04-08 | Smithsonian Astrophysical Observatory | Method and system for producing polarized 129 Xe gas |
NZ331509A (en) * | 1996-02-19 | 2000-04-28 | Nycomed Imaging As | Aqueous dispersions of stabilised gas microbubbles and their use as contrast agents |
BR9711082A (pt) * | 1996-03-29 | 2000-01-11 | Lawrence Berkeley National Lab | Realce de rmn emri na presença de gases mopbres hiperpolarizados. |
US5694934A (en) * | 1996-04-17 | 1997-12-09 | Beth Israel Hospital | MR studies in which a paramagnetic gas is administered to a living patient |
-
1998
- 1998-08-11 ES ES98935248T patent/ES2209167T3/es not_active Expired - Lifetime
- 1998-08-11 WO PCT/IB1998/001227 patent/WO1999007415A1/en active IP Right Grant
- 1998-08-11 DE DE69819309T patent/DE69819309T2/de not_active Expired - Lifetime
- 1998-08-11 AU AU84587/98A patent/AU726115C/en not_active Ceased
- 1998-08-11 JP JP51191899A patent/JP4317270B2/ja not_active Expired - Fee Related
- 1998-08-11 EP EP98935248A patent/EP0968000B1/en not_active Expired - Lifetime
- 1998-08-11 IL IL12917398A patent/IL129173A/en not_active IP Right Cessation
- 1998-08-11 AT AT98935248T patent/ATE252916T1/de not_active IP Right Cessation
- 1998-08-11 CN CN98801143A patent/CN1103605C/zh not_active Expired - Fee Related
- 1998-08-11 CA CA002268324A patent/CA2268324C/en not_active Expired - Fee Related
- 1998-08-12 US US09/132,763 patent/US6042809A/en not_active Expired - Lifetime
-
1999
- 1999-04-09 NO NO19991688A patent/NO313865B1/no not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
NO313865B1 (no) | 2002-12-16 |
IL129173A0 (en) | 2000-02-17 |
NO991688D0 (no) | 1999-04-09 |
AU726115B2 (en) | 2000-11-02 |
CA2268324A1 (en) | 1999-02-18 |
IL129173A (en) | 2002-03-10 |
DE69819309D1 (de) | 2003-12-04 |
DE69819309T2 (de) | 2004-07-15 |
EP0968000B1 (en) | 2003-10-29 |
EP0968000A1 (en) | 2000-01-05 |
ATE252916T1 (de) | 2003-11-15 |
CN1236323A (zh) | 1999-11-24 |
CN1103605C (zh) | 2003-03-26 |
WO1999007415A1 (en) | 1999-02-18 |
AU8458798A (en) | 1999-03-01 |
JP2001501977A (ja) | 2001-02-13 |
ES2209167T3 (es) | 2004-06-16 |
CA2268324C (en) | 2007-06-12 |
JP4317270B2 (ja) | 2009-08-19 |
US6042809A (en) | 2000-03-28 |
AU726115C (en) | 2001-12-20 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
NO991688L (no) | Administrerbare sammensetninger og fremgangsmÕter til magnetisk resonansavbildning | |
DK0836485T3 (da) | Kaskade-polymer-komplekser, fremgangsmåde til deres fremstilling og farmaceutiske midler indeholdende disse | |
ATE268187T1 (de) | Bioaktivierte diagnostische bilderzeugungskontrastmittel | |
ES2085617T3 (es) | Ion paramagnetico incluido en tamiz molecular para diagnostico. | |
WO2002046222A3 (en) | Compositions and methods for diagnosing alzheimer's disease | |
NO970273D0 (no) | Peptid-avledete radionuklid-chelatorer | |
YU61701A (sh) | Postupak i kit za efikasno radioobeležavanje proteina sa terapeutskim radioizotopom | |
ATE377381T1 (de) | Diffusionsbildgebung von gewebe | |
WO2001082793A3 (en) | Method and device for testing a sample of fresh whole blood | |
ATE376428T1 (de) | Metallkomplexverbindungen | |
WO2000015790A3 (en) | Leptin induced genes | |
ATE450800T1 (de) | Magnetstruktur für eine mri-vorrichtung und mri- vorrichtung | |
IS4172A (is) | Joðuð meðseglandi chelates, aðferð til framleiðslu þeirra, notkun efnanna og aðferðir til að auka virkni efnanna | |
ES2117670T3 (es) | Derivado de hidroxamato e hidrazida de poliaminas y su uso medico como agentes quelantes. | |
DK0786004T3 (da) | Kloning, ekspression og karakterisering af en hidtil ukendt form af phosphatidylinositol-3-kinase | |
ATE310736T1 (de) | Verbindungen zur bilddarstellung der alzheimer- krankenheit | |
SE9402880D0 (sv) | New peptide derivatives | |
DK1411992T3 (da) | Ioniske og ikke-ioniske, radiografiske kontrastmidler til anvendelse ved kombineret röntgenstråle- og kernemagnetisk resonansdiagnostik | |
HUP0202009A2 (hu) | Keratintartalmú rostok oxidációs festésére való készítmény és festési eljárás a készítmény alkalmazásával | |
ATE215367T1 (de) | Nimesulid enthaltende pharmazeutische zubereitung zur topischen anwendung | |
DE69732370D1 (de) | Spinresonanz kontrastmittel für das blut | |
DE60024891D1 (de) | Makrocyclische Chelatbildner für Metallopharmazeutika | |
UA28113C2 (uk) | Спосіб експрес-тестування ефективності реабілітації здоров'я людини | |
UA33330A (uk) | Спосіб діагностики ендогенної інтоксикації |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
MM1K | Lapsed by not paying the annual fees |