NO976061L - Human glandulær kallikrein-1 (hK2) - Google Patents

Human glandulær kallikrein-1 (hK2)

Info

Publication number
NO976061L
NO976061L NO976061A NO976061A NO976061L NO 976061 L NO976061 L NO 976061L NO 976061 A NO976061 A NO 976061A NO 976061 A NO976061 A NO 976061A NO 976061 L NO976061 L NO 976061L
Authority
NO
Norway
Prior art keywords
human
glandular kallikrein
arg226
human glandular
new form
Prior art date
Application number
NO976061A
Other languages
English (en)
Other versions
NO976061D0 (no
Inventor
Pirkko Vihko
Original Assignee
Orion Yhtymae Oyj
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Orion Yhtymae Oyj filed Critical Orion Yhtymae Oyj
Publication of NO976061D0 publication Critical patent/NO976061D0/no
Publication of NO976061L publication Critical patent/NO976061L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6445—Kallikreins (3.4.21.34; 3.4.21.35)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Optical Communication System (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Management, Administration, Business Operations System, And Electronic Commerce (AREA)
  • Telephonic Communication Services (AREA)
  • Mobile Radio Communication Systems (AREA)

Abstract

En ny form for human glandulær kallikrein-1 (hK2) er blitt oppdaget ved kloning av et prepro-hK2 cDNA fra et humant prostatacancervev cDNA bibliotek. Denne formen for hK2 er forskjellig i sekvens fra tidligere avledet sekvens for hK2 ved at Arger erstattet med Trp. Anvendelse av en baculovirus ekspresjonsvektor er beskrevet for oppnåelse av hK2 proteiner, inkludert ArghK2 som et aktivt modent protein direkte fra et kulturmedium.
NO976061A 1995-06-29 1997-12-23 Human glandulær kallikrein-1 (hK2) NO976061L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB9513281A GB2302874B (en) 1995-06-29 1995-06-29 Novel proteins
PCT/FI1996/000382 WO1997001630A1 (en) 1995-06-29 1996-06-28 HUMAN GLANDULAR KALLIKREIN-1 (hK2)

Publications (2)

Publication Number Publication Date
NO976061D0 NO976061D0 (no) 1997-12-23
NO976061L true NO976061L (no) 1998-02-11

Family

ID=10776879

Family Applications (1)

Application Number Title Priority Date Filing Date
NO976061A NO976061L (no) 1995-06-29 1997-12-23 Human glandulær kallikrein-1 (hK2)

Country Status (12)

Country Link
US (1) US6303361B1 (no)
EP (1) EP0837930B1 (no)
JP (1) JPH11508442A (no)
AT (1) ATE286533T1 (no)
AU (1) AU712917B2 (no)
CA (1) CA2224319A1 (no)
CZ (1) CZ417897A3 (no)
DE (1) DE69634153D1 (no)
GB (1) GB2302874B (no)
NO (1) NO976061L (no)
PL (1) PL184557B1 (no)
WO (1) WO1997001630A1 (no)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6103237A (en) * 1993-07-22 2000-08-15 Hybritech Incorporated Stable variant hK2 polypeptide
WO1998002748A1 (en) * 1996-07-15 1998-01-22 Mayo Foundation For Medical Education And Research Methods to detect hk2 polypeptides
US6479263B1 (en) 1996-11-14 2002-11-12 Baylor College Of Medicine Method for detection of micrometastatic prostate cancer
AU8259798A (en) 1997-06-20 1999-01-04 George G Klee Method for detection of breast cancer
FI980488A (fi) * 1998-03-04 1999-09-05 Arctic Partners Oy Ab Uusi diagnostinen menetelmä
CA2360073C (en) 1999-01-28 2011-01-18 Gen-Probe Incorporated Probes and primers for detecting prostate specific antigen (psa) in a biological sample
US20030207808A1 (en) * 1999-02-18 2003-11-06 Kinneret Savitzky Novel nucleic acid and amino acid sequences
WO2000049158A2 (en) * 1999-02-18 2000-08-24 Compugen Ltd. Psa and klk-2 splicing variants
US20020151029A1 (en) * 1999-11-23 2002-10-17 Holloway James L. Human serine protease
CN101868241A (zh) 2007-09-28 2010-10-20 英特瑞克斯顿股份有限公司 表达生物治疗分子的治疗基因开关构建物和生物反应器以及它们的应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5516639A (en) * 1993-07-22 1996-05-14 Mayo Foundation For Medical Education And Research Antibodies specific for human prostate glandular kallkrein
AU699748B2 (en) * 1994-05-10 1998-12-10 Hybritech Incorporated Recombinant HK2 polypeptide

Also Published As

Publication number Publication date
JPH11508442A (ja) 1999-07-27
WO1997001630A1 (en) 1997-01-16
PL324179A1 (en) 1998-05-11
DE69634153D1 (de) 2005-02-10
EP0837930A1 (en) 1998-04-29
US6303361B1 (en) 2001-10-16
CA2224319A1 (en) 1997-01-16
GB2302874B (en) 1999-11-10
AU6227396A (en) 1997-01-30
AU712917B2 (en) 1999-11-18
PL184557B1 (pl) 2002-11-29
GB9513281D0 (en) 1995-09-06
CZ417897A3 (cs) 1998-06-17
EP0837930B1 (en) 2005-01-05
ATE286533T1 (de) 2005-01-15
GB2302874A (en) 1997-02-05
NO976061D0 (no) 1997-12-23

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