NO976061L - Human glandulær kallikrein-1 (hK2) - Google Patents
Human glandulær kallikrein-1 (hK2)Info
- Publication number
- NO976061L NO976061L NO976061A NO976061A NO976061L NO 976061 L NO976061 L NO 976061L NO 976061 A NO976061 A NO 976061A NO 976061 A NO976061 A NO 976061A NO 976061 L NO976061 L NO 976061L
- Authority
- NO
- Norway
- Prior art keywords
- human
- glandular kallikrein
- arg226
- human glandular
- new form
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
- C12N9/6424—Serine endopeptidases (3.4.21)
- C12N9/6445—Kallikreins (3.4.21.34; 3.4.21.35)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Enzymes And Modification Thereof (AREA)
- Optical Communication System (AREA)
- Magnetic Resonance Imaging Apparatus (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Management, Administration, Business Operations System, And Electronic Commerce (AREA)
- Telephonic Communication Services (AREA)
- Mobile Radio Communication Systems (AREA)
Abstract
En ny form for human glandulær kallikrein-1 (hK2) er blitt oppdaget ved kloning av et prepro-hK2 cDNA fra et humant prostatacancervev cDNA bibliotek. Denne formen for hK2 er forskjellig i sekvens fra tidligere avledet sekvens for hK2 ved at Arger erstattet med Trp. Anvendelse av en baculovirus ekspresjonsvektor er beskrevet for oppnåelse av hK2 proteiner, inkludert ArghK2 som et aktivt modent protein direkte fra et kulturmedium.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB9513281A GB2302874B (en) | 1995-06-29 | 1995-06-29 | Novel proteins |
PCT/FI1996/000382 WO1997001630A1 (en) | 1995-06-29 | 1996-06-28 | HUMAN GLANDULAR KALLIKREIN-1 (hK2) |
Publications (2)
Publication Number | Publication Date |
---|---|
NO976061D0 NO976061D0 (no) | 1997-12-23 |
NO976061L true NO976061L (no) | 1998-02-11 |
Family
ID=10776879
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO976061A NO976061L (no) | 1995-06-29 | 1997-12-23 | Human glandulær kallikrein-1 (hK2) |
Country Status (12)
Country | Link |
---|---|
US (1) | US6303361B1 (no) |
EP (1) | EP0837930B1 (no) |
JP (1) | JPH11508442A (no) |
AT (1) | ATE286533T1 (no) |
AU (1) | AU712917B2 (no) |
CA (1) | CA2224319A1 (no) |
CZ (1) | CZ417897A3 (no) |
DE (1) | DE69634153D1 (no) |
GB (1) | GB2302874B (no) |
NO (1) | NO976061L (no) |
PL (1) | PL184557B1 (no) |
WO (1) | WO1997001630A1 (no) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6103237A (en) * | 1993-07-22 | 2000-08-15 | Hybritech Incorporated | Stable variant hK2 polypeptide |
WO1998002748A1 (en) * | 1996-07-15 | 1998-01-22 | Mayo Foundation For Medical Education And Research | Methods to detect hk2 polypeptides |
US6479263B1 (en) | 1996-11-14 | 2002-11-12 | Baylor College Of Medicine | Method for detection of micrometastatic prostate cancer |
AU8259798A (en) | 1997-06-20 | 1999-01-04 | George G Klee | Method for detection of breast cancer |
FI980488A (fi) * | 1998-03-04 | 1999-09-05 | Arctic Partners Oy Ab | Uusi diagnostinen menetelmä |
CA2360073C (en) | 1999-01-28 | 2011-01-18 | Gen-Probe Incorporated | Probes and primers for detecting prostate specific antigen (psa) in a biological sample |
US20030207808A1 (en) * | 1999-02-18 | 2003-11-06 | Kinneret Savitzky | Novel nucleic acid and amino acid sequences |
WO2000049158A2 (en) * | 1999-02-18 | 2000-08-24 | Compugen Ltd. | Psa and klk-2 splicing variants |
US20020151029A1 (en) * | 1999-11-23 | 2002-10-17 | Holloway James L. | Human serine protease |
CN101868241A (zh) | 2007-09-28 | 2010-10-20 | 英特瑞克斯顿股份有限公司 | 表达生物治疗分子的治疗基因开关构建物和生物反应器以及它们的应用 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5516639A (en) * | 1993-07-22 | 1996-05-14 | Mayo Foundation For Medical Education And Research | Antibodies specific for human prostate glandular kallkrein |
AU699748B2 (en) * | 1994-05-10 | 1998-12-10 | Hybritech Incorporated | Recombinant HK2 polypeptide |
-
1995
- 1995-06-29 GB GB9513281A patent/GB2302874B/en not_active Expired - Fee Related
-
1996
- 1996-06-28 JP JP9504194A patent/JPH11508442A/ja active Pending
- 1996-06-28 US US08/983,075 patent/US6303361B1/en not_active Expired - Fee Related
- 1996-06-28 CA CA002224319A patent/CA2224319A1/en not_active Abandoned
- 1996-06-28 DE DE69634153T patent/DE69634153D1/de not_active Expired - Lifetime
- 1996-06-28 AT AT96920863T patent/ATE286533T1/de not_active IP Right Cessation
- 1996-06-28 EP EP96920863A patent/EP0837930B1/en not_active Expired - Lifetime
- 1996-06-28 CZ CZ974178A patent/CZ417897A3/cs unknown
- 1996-06-28 PL PL96324179A patent/PL184557B1/pl not_active IP Right Cessation
- 1996-06-28 WO PCT/FI1996/000382 patent/WO1997001630A1/en active IP Right Grant
- 1996-06-28 AU AU62273/96A patent/AU712917B2/en not_active Ceased
-
1997
- 1997-12-23 NO NO976061A patent/NO976061L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
JPH11508442A (ja) | 1999-07-27 |
WO1997001630A1 (en) | 1997-01-16 |
PL324179A1 (en) | 1998-05-11 |
DE69634153D1 (de) | 2005-02-10 |
EP0837930A1 (en) | 1998-04-29 |
US6303361B1 (en) | 2001-10-16 |
CA2224319A1 (en) | 1997-01-16 |
GB2302874B (en) | 1999-11-10 |
AU6227396A (en) | 1997-01-30 |
AU712917B2 (en) | 1999-11-18 |
PL184557B1 (pl) | 2002-11-29 |
GB9513281D0 (en) | 1995-09-06 |
CZ417897A3 (cs) | 1998-06-17 |
EP0837930B1 (en) | 2005-01-05 |
ATE286533T1 (de) | 2005-01-15 |
GB2302874A (en) | 1997-02-05 |
NO976061D0 (no) | 1997-12-23 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FC2A | Withdrawal, rejection or dismissal of laid open patent application |