MX351578B - Circovirus porcino tipo 2 (pcv2), composicion inmunogenica que contiene el mismo, equipo de prueba y aplicacion del mismo. - Google Patents
Circovirus porcino tipo 2 (pcv2), composicion inmunogenica que contiene el mismo, equipo de prueba y aplicacion del mismo.Info
- Publication number
- MX351578B MX351578B MX2013007211A MX2013007211A MX351578B MX 351578 B MX351578 B MX 351578B MX 2013007211 A MX2013007211 A MX 2013007211A MX 2013007211 A MX2013007211 A MX 2013007211A MX 351578 B MX351578 B MX 351578B
- Authority
- MX
- Mexico
- Prior art keywords
- porcine circovirus
- composition containing
- circovirus type
- same
- assay kit
- Prior art date
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
- C07K16/081—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from DNA viruses
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
- C12Q1/701—Specific hybridization probes
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56983—Viruses
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5252—Virus inactivated (killed)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5254—Virus avirulent or attenuated
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
- A61K2039/552—Veterinary vaccine
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
- C12N2750/00011—Details
- C12N2750/00061—Methods of inactivation or attenuation
- C12N2750/00063—Methods of inactivation or attenuation by chemical treatment
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
- C12N2750/00011—Details
- C12N2750/10011—Circoviridae
- C12N2750/10021—Viruses as such, e.g. new isolates, mutants or their genomic sequences
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
- C12N2750/00011—Details
- C12N2750/10011—Circoviridae
- C12N2750/10034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
- C12N2750/00011—Details
- C12N2750/10011—Circoviridae
- C12N2750/10071—Demonstrated in vivo effect
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/005—Assays involving biological materials from specific organisms or of a specific nature from viruses
- G01N2333/01—DNA viruses
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2469/00—Immunoassays for the detection of microorganisms
- G01N2469/20—Detection of antibodies in sample from host which are directed against antigens from microorganisms
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- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
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- Hematology (AREA)
- Urology & Nephrology (AREA)
- Biophysics (AREA)
- General Engineering & Computer Science (AREA)
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Abstract
La presente invención se refiere a una composición inmunogénica, que comprende una forma inactivada del virus circovirus porcino topo 2 (PCV2), en donde el virus circovirus porcino tipo 2 (PCV2) comprende la secuencia de genoma de SEQ ID NO: 1, y es inactivado por al menos uno de un formaldehido, paraformaldehido, beta-propiolactona (BLP), y etilenimina binaria (BEI).
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201061426087P | 2010-12-22 | 2010-12-22 | |
PCT/CN2011/084277 WO2012083837A1 (zh) | 2010-12-22 | 2011-12-20 | 猪第二型环状病毒、含彼的免疫组合物、检测套组及其应用 |
Publications (2)
Publication Number | Publication Date |
---|---|
MX2013007211A MX2013007211A (es) | 2014-03-12 |
MX351578B true MX351578B (es) | 2017-10-19 |
Family
ID=46313165
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2013007211A MX351578B (es) | 2010-12-22 | 2011-12-20 | Circovirus porcino tipo 2 (pcv2), composicion inmunogenica que contiene el mismo, equipo de prueba y aplicacion del mismo. |
Country Status (14)
Country | Link |
---|---|
US (2) | US9101571B2 (es) |
EP (2) | EP2657333B1 (es) |
JP (2) | JP2014507124A (es) |
KR (1) | KR101740764B1 (es) |
CN (1) | CN103314103B (es) |
AU (1) | AU2011348702B2 (es) |
BR (1) | BR112013015675A2 (es) |
DK (1) | DK2657333T3 (es) |
EA (1) | EA028376B1 (es) |
ES (1) | ES2763327T3 (es) |
MX (1) | MX351578B (es) |
TW (2) | TWI442935B (es) |
UA (1) | UA110632C2 (es) |
WO (1) | WO2012083837A1 (es) |
Families Citing this family (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
UA113192C2 (xx) * | 2011-12-06 | 2016-12-26 | Імуногенна композиція проти цирковірусу свиней типу 2 (pcv2) | |
CN103893750B (zh) * | 2012-12-31 | 2015-11-25 | 普莱柯生物工程股份有限公司 | 一种抗猪伪狂犬病、猪流感疫苗组合物及其应用 |
WO2014182872A1 (en) | 2013-05-08 | 2014-11-13 | Protatek International, Inc. | Vaccine for pcv2 and mycoplasma |
ES2932410T3 (es) | 2013-08-23 | 2023-01-18 | Boehringer Ingelheim Animal Health Usa Inc | Vacuna de subunidad de circovirus porcino tipo 2 (PCV2) |
CN104749361B (zh) * | 2015-01-21 | 2017-04-19 | 中国农业科学院哈尔滨兽医研究所 | 猪圆环病毒2型抗原捕获elisa试剂盒 |
CN105445457B (zh) * | 2015-03-24 | 2017-08-11 | 中国农业科学院哈尔滨兽医研究所 | 检测猪圆环病毒2型Cap蛋白的单克隆抗体及试剂盒 |
US9944904B2 (en) * | 2015-05-14 | 2018-04-17 | Merial Inc. | Method for porcine circovirus production and PCV2 vaccines |
CN105606804A (zh) * | 2016-01-20 | 2016-05-25 | 福州大北农生物技术有限公司 | 一种猪圆环病毒灭活疫苗效力检验方法 |
CN107686833B (zh) * | 2016-04-18 | 2021-02-19 | 华南农业大学 | 一种猪细小病毒毒株及其应用 |
KR102669319B1 (ko) | 2016-11-03 | 2024-05-28 | 베링거잉겔하임베트메디카게엠베하 | 돼지 파보바이러스에 대한 백신 |
MX2019005136A (es) | 2016-11-03 | 2019-06-20 | Boehringer Ingelheim Vetmedica Gmbh | Vacuna contra el parvovirus porcino y el virus del sindrome respiratorio reproductivo porcino y metodos de produccion de esta. |
CN109206509B (zh) * | 2017-06-29 | 2021-07-20 | 洛阳普泰生物技术有限公司 | 与伪狂犬病病毒gD蛋白结合的单克隆抗体及其应用 |
CN107308446B (zh) * | 2017-07-14 | 2021-03-23 | 瑞普(保定)生物药业有限公司 | 一种猪圆环病毒2型灭活疫苗的生产方法 |
CN107227380A (zh) * | 2017-07-26 | 2017-10-03 | 杭州师范大学 | 一种同步检测pcv2和prv感染的引物序列及方法 |
CN110343670B (zh) * | 2018-04-04 | 2022-08-30 | 普莱柯生物工程股份有限公司 | 表达猪圆环病毒Cap蛋白基因的重组猪伪狂犬病病毒弱毒株、及其制备方法和应用 |
CN110387355B (zh) * | 2018-04-18 | 2022-08-30 | 普莱柯生物工程股份有限公司 | 表达猪圆环病毒Cap蛋白基因的重组猪伪狂犬病病毒株、疫苗及其制备方法和应用 |
MX2020013484A (es) * | 2018-06-11 | 2021-05-27 | Ceva Sante Animale | Vacunacion contra circovirus porcinos. |
CN109468413B (zh) * | 2018-12-14 | 2021-09-10 | 湖南中净生物科技有限公司 | 一种母猪繁殖障碍病原检测引物、试剂盒、病原检测方法和应用 |
RU2697849C1 (ru) * | 2019-04-26 | 2019-08-21 | Федеральное государственное бюджетное научное учреждение "Всероссийский научно-исследовательский и технологический институт биологической промышленности" (ФГБНУ ВНИТИБП) | Способ диагностики цирковируса свиней |
CN110041409B (zh) * | 2019-05-07 | 2022-09-06 | 山东省农业科学院畜牧兽医研究所 | 一种突变型猪圆环病毒2型病毒及应用 |
CN110698542B (zh) * | 2019-09-16 | 2022-03-22 | 长江大学 | 人工改造的猪圆环病毒2型Rep′蛋白、ELISA检测试剂盒及其应用 |
CN110711202B (zh) * | 2019-10-25 | 2022-08-19 | 湖南农业大学 | Phb2基因或蛋白的抑制剂在制备抗猪圆环病毒2型药物中的应用 |
FR3120944A1 (fr) | 2021-03-21 | 2022-09-23 | Virbac | Procédé de détermination de l’âge optimum de vaccination de porcelets par mesure d’une teneur en anticorps dans le colostrum de truies au sein d’un élevage |
CN114317456A (zh) * | 2021-12-15 | 2022-04-12 | 成都史纪生物制药有限公司 | 一种猪圆环病毒2型毒株的灭活方法及猪圆环病毒疫苗 |
CN115094060A (zh) * | 2022-06-23 | 2022-09-23 | 湖南农业大学 | 基于LAMP-CRISPR/Cas12a可视化检测PCV2核酸的试剂盒及方法 |
CN115947794A (zh) * | 2022-07-19 | 2023-04-11 | 沈阳农业大学 | 一种pcv2 orf3特异性多肽及应用 |
CN116813718B (zh) * | 2023-08-30 | 2023-10-27 | 北京瑞阳瑞泰生物科技有限公司 | 一种重组猪圆环病毒2型Cap蛋白三聚体及其表达体系和应用 |
Family Cites Families (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6517843B1 (en) | 1999-08-31 | 2003-02-11 | Merial | Reduction of porcine circovirus-2 viral load with inactivated PCV-2 |
US7192594B2 (en) | 1997-10-03 | 2007-03-20 | Merial Limited | Postweaning multisystemic wasting syndrome and porcine circovirus from pigs |
US6391314B1 (en) | 1997-10-03 | 2002-05-21 | Merial | Porcine circoviruses vaccines diagnostic reagents |
FR2781159B1 (fr) | 1998-07-06 | 2000-10-06 | Merial Sas | Vaccin circovirus et parvovirus porcin |
US7211379B2 (en) | 1997-10-03 | 2007-05-01 | Merial Sas | Prevention of myocarditis, abortion and intrauterine infection associated with porcine circovirus-2 |
UA78180C2 (uk) | 1997-10-03 | 2007-03-15 | Меріаль | Кільцевий вірус свині типу ii, вакцини та діагностичні реагенти |
US20040062775A1 (en) | 1997-12-05 | 2004-04-01 | Agence Francaise De Securite Sanitaire Des Aliments | Circovirus sequences associated with piglet weight loss disease (PWD) |
FR2772047B1 (fr) | 1997-12-05 | 2004-04-09 | Ct Nat D Etudes Veterinaires E | Sequence genomique et polypeptides de circovirus associe a la maladie de l'amaigrissement du porcelet (map), applications au diagnostic et a la prevention et/ou au traitement de l'infection |
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EP1941903A1 (en) * | 2007-01-03 | 2008-07-09 | Boehringer Ingelheim Vetmedica Gmbh | Prophylaxis and treatment of PRDC |
CA2712006A1 (en) * | 2008-01-23 | 2009-10-15 | Boehringer Ingelheim Vetmedica, Inc. | Pcv2 mycoplasma hyopneumoniae immunogenic compositions and methods of producing such compositions |
CN101343671A (zh) * | 2008-08-25 | 2009-01-14 | 湖南省兽医总站 | 猪2型圆环病毒pcr快速检测试剂盒 |
TWI367256B (en) * | 2008-10-07 | 2012-07-01 | Academia Sinica | Vaccine composition and kit providing protective immunity against porcine circovirus 2 |
KR20110128267A (ko) * | 2008-11-28 | 2011-11-29 | 세바 상뜨 아니말르 | 신규 돼지 시르코바이러스 2비 형 분리물 및 이의 용도 |
CN101549155B (zh) * | 2009-05-27 | 2012-05-09 | 福州大北农生物技术有限公司 | 猪圆环病毒ⅱ型灭活疫苗及其制备方法 |
UA113192C2 (xx) * | 2011-12-06 | 2016-12-26 | Імуногенна композиція проти цирковірусу свиней типу 2 (pcv2) |
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2011
- 2011-12-14 TW TW100146224A patent/TWI442935B/zh active
- 2011-12-14 TW TW103118244A patent/TWI508974B/zh active
- 2011-12-20 BR BR112013015675-9A patent/BR112013015675A2/pt not_active Application Discontinuation
- 2011-12-20 EA EA201370140A patent/EA028376B1/ru unknown
- 2011-12-20 MX MX2013007211A patent/MX351578B/es active IP Right Grant
- 2011-12-20 KR KR1020137019260A patent/KR101740764B1/ko active IP Right Grant
- 2011-12-20 DK DK11851859T patent/DK2657333T3/da active
- 2011-12-20 UA UAA201309034A patent/UA110632C2/uk unknown
- 2011-12-20 US US13/332,269 patent/US9101571B2/en active Active
- 2011-12-20 AU AU2011348702A patent/AU2011348702B2/en active Active
- 2011-12-20 EP EP11851859.6A patent/EP2657333B1/en active Active
- 2011-12-20 EP EP19196163.0A patent/EP3604504A1/en not_active Withdrawn
- 2011-12-20 JP JP2013545025A patent/JP2014507124A/ja active Pending
- 2011-12-20 CN CN201180061073.6A patent/CN103314103B/zh active Active
- 2011-12-20 WO PCT/CN2011/084277 patent/WO2012083837A1/zh active Application Filing
- 2011-12-20 ES ES11851859T patent/ES2763327T3/es active Active
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Also Published As
Publication number | Publication date |
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TW201437226A (zh) | 2014-10-01 |
EP3604504A1 (en) | 2020-02-05 |
ES2763327T3 (es) | 2020-05-28 |
KR20130098430A (ko) | 2013-09-04 |
TWI508974B (zh) | 2015-11-21 |
TW201225975A (en) | 2012-07-01 |
EP2657333B1 (en) | 2019-10-02 |
US9101571B2 (en) | 2015-08-11 |
AU2011348702A1 (en) | 2013-07-18 |
BR112013015675A2 (pt) | 2020-10-06 |
EA028376B1 (ru) | 2017-11-30 |
US20120164170A1 (en) | 2012-06-28 |
JP2014507124A (ja) | 2014-03-27 |
US9770501B2 (en) | 2017-09-26 |
JP2016052313A (ja) | 2016-04-14 |
JP6150864B2 (ja) | 2017-06-21 |
EP2657333A4 (en) | 2014-11-12 |
AU2011348702B2 (en) | 2016-06-16 |
MX2013007211A (es) | 2014-03-12 |
DK2657333T3 (da) | 2019-12-09 |
EP2657333A1 (en) | 2013-10-30 |
CN103314103B (zh) | 2015-06-24 |
US20150297709A1 (en) | 2015-10-22 |
EA201370140A1 (ru) | 2013-10-30 |
TWI442935B (zh) | 2014-07-01 |
WO2012083837A1 (zh) | 2012-06-28 |
CN103314103A (zh) | 2013-09-18 |
UA110632C2 (uk) | 2016-01-25 |
KR101740764B1 (ko) | 2017-05-26 |
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