KR930703302A - 피페리딘 유도체 - Google Patents
피페리딘 유도체Info
- Publication number
- KR930703302A KR930703302A KR1019930702072A KR930702072A KR930703302A KR 930703302 A KR930703302 A KR 930703302A KR 1019930702072 A KR1019930702072 A KR 1019930702072A KR 930702072 A KR930702072 A KR 930702072A KR 930703302 A KR930703302 A KR 930703302A
- Authority
- KR
- South Korea
- Prior art keywords
- group
- compound
- phenyl
- alkyl
- acid addition
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/34—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom
- A01N43/40—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom six-membered rings
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/72—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms
- A01N43/74—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms five-membered rings with one nitrogen atom and either one oxygen atom or one sulfur atom in positions 1,3
- A01N43/78—1,3-Thiazoles; Hydrogenated 1,3-thiazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/10—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms
- C07D211/14—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms with hydrocarbon or substituted hydrocarbon radicals attached to the ring nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Agronomy & Crop Science (AREA)
- Pest Control & Pesticides (AREA)
- Plant Pathology (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Dentistry (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- Hydrogenated Pyridines (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
발명은 일반식(Ⅰ)의 피페리딘 유도체 또는 그의 산부가염(이때 R은 임의로 치환된 알킬, 시클로알킬, 아릴 또는 헤테로시클로알킬을 나타내고, R1은 임의로 치횐돤 알킬, 알케닐, 알키닐, 시클로알킬, 아릴 또는 헤테로시클릴기를 나타내고, m은 0내지 3의 정수를 나타내고, R2및 R3각각은 독립적으로 수소 원자, 알킬 및 페닐기로 구성되는 군으로부터 선택되되, 단 R은 4-삼차부틸 페닐기를 나타내지 않는다.), 및 그의 제조방법, 상기 화합물을 함유하는 조성물 및 살균제로서 그들의 사용을 제공한다.
Description
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
Claims (10)
- 다음 일반식의 화합물 또는 그의 산부가염:식에서 R은 임으로 치환된 알킬, 시클로알킬, 아릴 또는 헤테로시클기를 나타내고;R1은 임의로 치환된 알킬, 알케닐, 알키닐, 시클로알킬, 아릴 또는 헤테로시클릴기를 나타내고 m은 1내지 3의 정수를 나타내고 R2및 R3각각은 독립적으로 수소원자, 알킬 및 페닐기로 구성되는 군으로부터 선택되되, 단R은 4-삼차부틸 페닐기를 나타내지 않는다.
- 제1항에 있어서, R은 할로겐원자, 니트로, 시아노, 히드록실, C1-4알킬, C1-4할로알킬, C1-4알콕시, C1-4할로알콕시, 아미노, C1-4알킬아미노, 디-C1-4알킬아미노, 포르밀, C1-4알콕시카르보닐, 카르복실 및 페닐기로부터 선택된 하나 이상의 치환체로 임의로 치환된 나프틸기 또는 페닐기를 나타내는 화합물.
- 제1항 또는 제2항에 있어서, R1은 C1-12알킬, C2-12알케닐, C2-12알키닐, C3-8시클로알킬, 나프틸, 페닐, 피리딜 또는 티아졸릴기를 나타내고, 각각의 기는 할로겐 원자, 니트로, 시아노, 히드록실, C1-4알킬, C1-4할로알킬, C1-4알콕시, C1-4할로알콕시, 아미노, C1-4알킬아미노, 디-C1-4알킬아미노, 포르밀, C1-4알콕시카르보닐, 카르복실, 페닐, 할로페닐 및 페녹시기로부터 선택된 하나 이상의 치환체로 임의로 화합물.
- 제1-3항중 암의의 한항에 있어서, R은 나프틸, 페닐, 플루오르페닐, 클로로페닐, 브로모페닐, 니트로페닐, 메틸페닐, 메톡시페닐, 아미노페닐 또는 비페닐릴기를 나타내고, R1은 에틸, 프로필, 부틸, 펜틸, 헥실, 헵틸, 옥틸, 페녹시에틸, 프로페닐, 부페닐, 펜테닐, 헥세닐, 페닐프로페닐, 프로피닐, 부티닐, 펜티닐, 헥시닐, 시클로헥실, 히드록시시클로헥실, 나프틸, 페닐, 플루오로페닐, 클로로페닐, 티클로로페닐, 브로모페닐, 니트로페닐, 시아노페닐, 메틸페닐, 부틸페닐, 트리플루오로메틸페닐, 메톡시페닐, 메톡시카르보닐페닐, 비페닐릴, 피리딜 또는 클로로페닐-티아졸릴기를 나타낸고, R2는 수소 원자 또는 메틸 또는 페닐기를 나타내고 R3는 수소원자를 나타내는 화합물.
- 일반식(이때 R은 상기 항들중 임의의 한 항에서 정의한 바와 같다)의 화합물을, 일반식X-(CR1R2)m-R1(Ⅲ)(이때 m, R1, R2,및 R3는 상기 항들중 임의의 한 항에서 정의한 바와 같고 X는 이탈기를 나타낸다)의 화합물과 반응시키고, 원하면, 이렇게 얻은 일반식 Ⅰ화합물을 적당한 산과 반응시켜 그의 산부가염을 형성함으로 구성되는, 제1항 내지 제4항중 임의의 한 항에서 정의한 일반 Ⅰ화합물 또는 그의 산부가염의 제조방법.
- 부형체 및, 활성성분으로서, 제1항 내지 제4항중 임의의 한 항에서 정의된 일반 Ⅰ 화합물 또는 그의 산부가염으로 구성되는 살균조성물.
- 제6항에 있어서, 적어도 2가지의 부형제를 포함하며, 그중 적어도 하나의 계면활성제인 조성물.
- 한 장소를 제1항 내지 제4항중 임의의 한 항에서 정의된 일반식 Ⅰ 화합물, 또는 그의 산부가염으로, 또는 제6항 또는 제7항에서 정의된 조성물로 처리함으로 구성되는 , 한 장소에서 진균을 방제하는 방법.
- 제8항에 있어서, 장소는 진균 공격을 받기 쉽거나 받은 식물, 상기 식물의 종자 또는 식물이 성장하고 있거나 성장할 매질을 포함하는 방법.
- 살균제로서 제1항 내지 제4항중 임의의 한 항에서 정의된 일반식 Ⅰ화합물 또는 그의 산부가염 또는 제6항 또는 제 7항에서 정의된 조성물의 사용.※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB919100505A GB9100505D0 (en) | 1991-01-10 | 1991-01-10 | Piperidine derivatives |
GB9100505.8 | 1991-01-10 | ||
PCT/EP1992/000040 WO1992012130A1 (en) | 1991-01-10 | 1992-01-08 | Piperidine derivatives |
Publications (1)
Publication Number | Publication Date |
---|---|
KR930703302A true KR930703302A (ko) | 1993-11-29 |
Family
ID=10688228
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR1019930702072A KR930703302A (ko) | 1991-01-10 | 1992-01-08 | 피페리딘 유도체 |
Country Status (12)
Country | Link |
---|---|
US (1) | US5489599A (ko) |
EP (1) | EP0494717A1 (ko) |
JP (1) | JPH06506441A (ko) |
KR (1) | KR930703302A (ko) |
CN (1) | CN1063101A (ko) |
CS (1) | CS4492A3 (ko) |
GB (1) | GB9100505D0 (ko) |
HU (1) | HUT65119A (ko) |
RU (1) | RU2097375C1 (ko) |
TR (1) | TR28066A (ko) |
WO (1) | WO1992012130A1 (ko) |
ZA (1) | ZA92149B (ko) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU4566093A (en) * | 1992-07-08 | 1994-01-31 | Shell Internationale Research Maatschappij B.V. | Piperidine derivatives |
DE4335718A1 (de) * | 1993-10-20 | 1995-04-27 | Merck Patent Gmbh | Cyclische Aminderivate |
ZA9610738B (en) * | 1995-12-22 | 1997-06-24 | Warner Lambert Co | Subtype selective nmda receptor ligands and the use thereof |
KR100537843B1 (ko) * | 1996-07-22 | 2006-04-28 | 다이이치 아스비오파마 가부시키가이샤 | 아릴피페리디놀및아릴피페리딘유도체및이들을함유하는약제 |
US5849802A (en) * | 1996-09-27 | 1998-12-15 | American Cyanamid Company | Fungicidal spirocyclic amines |
GB9710004D0 (en) * | 1997-05-17 | 1997-07-09 | Knoll Ag | Chemical process |
US6136827A (en) * | 1997-07-25 | 2000-10-24 | Merck & Co., Inc. | Cyclic amine modulations of chemokine receptor activity |
WO1999004794A1 (en) * | 1997-07-25 | 1999-02-04 | Merck & Co., Inc. | Cyclic amine modulators of chemokine receptor activity |
US6262066B1 (en) | 1998-07-27 | 2001-07-17 | Schering Corporation | High affinity ligands for nociceptin receptor ORL-1 |
CO5150201A1 (es) * | 1998-09-07 | 2002-04-29 | Hoffmann La Roche | Derivados de piperidina |
IT1303737B1 (it) * | 1998-11-11 | 2001-02-23 | Smithkline Beecham Spa | Derivati fenilpiperidinici procedimento per la loro preparazione eloro uso come ligandi del recettore orl-1. |
US7217714B1 (en) * | 1998-12-23 | 2007-05-15 | Agouron Pharmaceuticals, Inc. | CCR5 modulators |
GB9912417D0 (en) | 1999-05-28 | 1999-07-28 | Pfizer Ltd | Compounds useful in therapy |
GB9912411D0 (en) * | 1999-05-28 | 1999-07-28 | Pfizer Ltd | Compounds useful in therapy |
CA2414198A1 (en) * | 2000-07-06 | 2002-01-17 | Neurogen Corporation | Melanin concentrating hormone receptor ligands |
AU2002360561A1 (en) | 2001-12-11 | 2003-06-23 | Sepracor, Inc. | 4-substituted piperidines, and methods of use thereof |
GB0414438D0 (en) * | 2004-06-28 | 2004-07-28 | Syngenta Participations Ag | Chemical compounds |
EP1923394A1 (en) * | 2006-11-16 | 2008-05-21 | Sandoz A/S | Reagent and use thereof for the production of bisphosphonates |
US7748454B2 (en) * | 2008-04-28 | 2010-07-06 | Halliburton Energy Services, Inc. | Gelation inhibiting retarders for highly reactive calcium silicate based binder compositions and methods of making and using same |
Family Cites Families (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB801792A (en) * | 1955-08-18 | 1958-09-24 | Smith & Nephew | Improvements in or relating to heterocyclic nitrogen-containing compounds |
US2956058A (en) * | 1957-08-19 | 1960-10-11 | Lilly Co Eli | Novel substituted piperidines and pyrrolidines |
GB948071A (en) | 1959-05-01 | 1964-01-29 | May & Baker Ltd | New heterocyclic compounds |
FR1421210A (fr) * | 1960-02-02 | 1965-12-17 | May & Baker Ltd | Nouveaux dérivés de la pipérazine |
GB1044309A (en) * | 1964-05-07 | 1966-09-28 | Koninklijke Pharma Fab Nv | Substituted 1-aralklyl-piperidines |
GB1060160A (en) * | 1964-08-05 | 1967-03-01 | Allen & Hanburys Ltd | 4-phenylpiperidine derivatives |
FR2096916A1 (en) * | 1970-07-16 | 1972-03-03 | Synthelabo | 1-(3,3-diphenylpropyl)-4-phenyl piperidine - analgesic and antiinflammatory |
DE2727482A1 (de) * | 1977-06-18 | 1979-01-11 | Basf Ag | Derivate cyclischer amine |
FI792076A (fi) * | 1978-07-05 | 1980-01-06 | Ciba Geigy Ag | Foerfarande foer framstaellning av nya fenylpiperidinderivat |
GB2083476B (en) * | 1980-09-12 | 1984-02-08 | Wyeth John & Brother Ltd | Heterocyclic compounds |
DE3441929A1 (de) * | 1984-11-16 | 1986-05-28 | Basf Ag, 6700 Ludwigshafen | Verfahren zur herstellung von substituierten piperidinen |
GB2177085A (en) * | 1985-06-18 | 1987-01-14 | Ici Plc | Fungicidal compounds and compositions |
DE3614907A1 (de) * | 1986-05-02 | 1987-11-05 | Basf Ag | N-substituierte pyrrolidon- und piperidinderivate und deren salze |
GB8710494D0 (en) * | 1987-05-02 | 1987-06-03 | Pfizer Ltd | Antiarrhythmic agents |
KR900701774A (ko) * | 1988-08-16 | 1990-12-04 | 제임스 제이. 플린 | 살진균성 벤조디옥산 아민 유도체 |
DE3838631A1 (de) * | 1988-11-15 | 1990-05-23 | Basf Ag | Neue 2-aminodekalin-derivate und deren verwendung |
WO1990006303A1 (en) * | 1988-12-02 | 1990-06-14 | Pfizer Inc. | Arylpiperidine derivatives |
DE3901244A1 (de) * | 1989-01-18 | 1990-07-19 | Basf Ag | Phenylalkylamine und diese enthaltende fungizide |
-
1991
- 1991-01-10 GB GB919100505A patent/GB9100505D0/en active Pending
-
1992
- 1992-01-08 WO PCT/EP1992/000040 patent/WO1992012130A1/en active Application Filing
- 1992-01-08 KR KR1019930702072A patent/KR930703302A/ko not_active Application Discontinuation
- 1992-01-08 HU HU9301987A patent/HUT65119A/hu unknown
- 1992-01-08 US US08/081,298 patent/US5489599A/en not_active Expired - Fee Related
- 1992-01-08 CS CS9244A patent/CS4492A3/cs unknown
- 1992-01-08 JP JP4501676A patent/JPH06506441A/ja active Pending
- 1992-01-08 EP EP92200037A patent/EP0494717A1/en not_active Withdrawn
- 1992-01-08 RU RU9293051789A patent/RU2097375C1/ru active
- 1992-01-09 ZA ZA92149A patent/ZA92149B/xx unknown
- 1992-01-10 TR TR00032/92A patent/TR28066A/xx unknown
- 1992-01-10 CN CN92100196A patent/CN1063101A/zh active Pending
Also Published As
Publication number | Publication date |
---|---|
US5489599A (en) | 1996-02-06 |
WO1992012130A1 (en) | 1992-07-23 |
JPH06506441A (ja) | 1994-07-21 |
CN1063101A (zh) | 1992-07-29 |
TR28066A (tr) | 1995-12-11 |
HU9301987D0 (en) | 1993-11-29 |
ZA92149B (en) | 1992-09-30 |
HUT65119A (en) | 1994-04-28 |
RU2097375C1 (ru) | 1997-11-27 |
GB9100505D0 (en) | 1991-02-20 |
EP0494717A1 (en) | 1992-07-15 |
CS4492A3 (en) | 1992-07-15 |
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