KR840005092A - 벤조페논 유도체의 제조방법 - Google Patents
벤조페논 유도체의 제조방법 Download PDFInfo
- Publication number
- KR840005092A KR840005092A KR1019830001861A KR830001861A KR840005092A KR 840005092 A KR840005092 A KR 840005092A KR 1019830001861 A KR1019830001861 A KR 1019830001861A KR 830001861 A KR830001861 A KR 830001861A KR 840005092 A KR840005092 A KR 840005092A
- Authority
- KR
- South Korea
- Prior art keywords
- formula
- phenyl
- anion
- alkyl
- sulfonamide
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
- C07C205/49—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups
- C07C205/57—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups having nitro groups and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
- C07C205/58—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups having nitro groups and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton the carbon skeleton being further substituted by halogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C201/00—Preparation of esters of nitric or nitrous acid or of compounds containing nitro or nitroso groups bound to a carbon skeleton
- C07C201/06—Preparation of nitro compounds
- C07C201/12—Preparation of nitro compounds by reactions not involving the formation of nitro groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
- C07C205/45—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by at least one doubly—bound oxygen atom, not being part of a —CHO group
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C303/00—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides
- C07C303/36—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of amides of sulfonic acids
- C07C303/40—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of amides of sulfonic acids by reactions not involving the formation of sulfonamide groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/01—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms
- C07C311/02—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
- C07C311/08—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton having the nitrogen atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D235/30—Nitrogen atoms not forming part of a nitro radical
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
Abstract
내용 없음
Description
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
Claims (5)
- 하기 일반식(Ⅲ)의 3―플루오로―4―니트로벤조페논을 일반식(Ⅳ)의 설폰아미드의 음이온과 반응시킴을 특징으로 하여 하기 일반식(I)의 화합물을 제조하는 방법.R1은 C1내지 C5알킬, C3내지 C7시클로알킬, 페닐, 푸릴, 티에닐, 티아졸―2―일, 1,3,4―티아디아졸―2―일, 2―메틸―1,3,4―티아디아졸―5―일 또는 R4R5N(여기서 R4및 R5는 각각 독립적으로 C1내지 C3의 알킬이거나, R4및 R5는 이들이 결합된 질소원자와 함께 피롤리디노, 피페리디노 또는 모폴리노를 형성한다)이고 R2는 페닐 또는 C1내지 C4알킬 C1내지 C4알콕시 클로로, 브로모, 요도 또는 트리플루오로메틸로 치환된 페닐이며 R3는 ―NO2를 표시한다.
- 제1항에 있어서, 음이온을 비―반응성용매 존재하 0내지 100°C의 온도에서 강염기와 작용시킴으로써 생성하는 방법.
- 제1항 또는 2항에 있어서, 음이온을 일반식(Ⅳ)의 설폰아미드를 수소화나트륨과 작용시킴으로써 생성하는 방법.
- 제1항에 있어서, R2가 페닐인 방법.
- 제1항에 또는 3항에 있어서, R1이 이소―프로필인 방법.※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US06/373,945 US4483986A (en) | 1982-05-03 | 1982-05-03 | 4-Nitrobenzophenone compounds |
US373,945 | 1982-05-03 |
Publications (1)
Publication Number | Publication Date |
---|---|
KR840005092A true KR840005092A (ko) | 1984-11-03 |
Family
ID=23474565
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR1019830001861A KR840005092A (ko) | 1982-05-03 | 1983-05-02 | 벤조페논 유도체의 제조방법 |
Country Status (7)
Country | Link |
---|---|
US (1) | US4483986A (ko) |
EP (1) | EP0093590A1 (ko) |
JP (1) | JPS58208264A (ko) |
KR (1) | KR840005092A (ko) |
DK (1) | DK194083A (ko) |
GB (1) | GB2119379B (ko) |
GR (1) | GR78540B (ko) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP3312629B2 (ja) * | 1991-01-23 | 2002-08-12 | 日産化学工業株式会社 | アニリン誘導体及び製法 |
DE4131844A1 (de) * | 1991-09-25 | 1993-04-01 | Basf Ag | Verfahren zur herstellung von nitrobenzophenonen sowie faerbestabile modifikation eines benzophenonazopyridonfarbstoffs |
US6284923B1 (en) | 1997-08-22 | 2001-09-04 | Tularik Inc | Substituted benzene compounds as antiproliferative and cholesterol lowering action |
WO2002039958A2 (en) | 2000-11-03 | 2002-05-23 | Tularik Inc. | Combination therapy using pentafluorobenzenesulfonamides and antineoplastic agents |
US20050250854A1 (en) * | 2000-11-03 | 2005-11-10 | Amgen Inc. | Combination therapy using pentafluorobenzenesulfonamides and antineoplastic agents |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NL124621C (ko) * | 1962-11-13 | |||
US3576866A (en) * | 1969-06-12 | 1971-04-27 | Minnesota Mining & Mfg | Benzoylhaloalkanesulfonanilides |
GB1340428A (en) * | 1971-04-13 | 1973-12-12 | Ici Ltd | Benzothiadiazine derivatives their preparation and veterinary and pharmaceutical compositions containing them |
GB1395893A (en) * | 1971-05-21 | 1975-05-29 | Wellcome Found | Cyanophenols their preparation andderivatives thereof |
FR2181790A1 (en) * | 1972-03-07 | 1973-12-07 | Janssen Pharmaceutica Nv | Salicylic acid anilides - from salicylic halides and aniline derivs, anthel-mintics, coccidiostatics |
US3846477A (en) * | 1972-09-20 | 1974-11-05 | Robins Co Inc A H | 2-alkylamino benzophenones |
US4174454A (en) * | 1975-08-28 | 1979-11-13 | Eli Lilly And Company | Alkylidenylmethyl-substituted 1-sulfonylbenzimidazoles |
NZ181789A (en) * | 1975-08-28 | 1979-01-11 | Lilly Co Eli | 5(6)-substituted-1-hydrocarbylulphanyl-2-amino-bezimidazoles |
DE2724073A1 (de) * | 1976-06-03 | 1977-12-22 | Fujisawa Pharmaceutical Co | 3,7-disubstituierte 3-cephem-4- carbonsaeuren und sie enthaltende pharmazeutische zubereitungen |
US4312996A (en) * | 1980-12-29 | 1982-01-26 | Schering Corporation | Benzodiazepine intermediates |
US4313000A (en) * | 1981-04-02 | 1982-01-26 | Ici Americas Inc. | Process for preparing 5-(2-chloro-4-trifluoromethylphenoxy)-2-nitro-N-alkanesulphonyl benzamides from a toluene derivative and intermediates |
-
1982
- 1982-05-03 US US06/373,945 patent/US4483986A/en not_active Expired - Fee Related
-
1983
- 1983-04-28 JP JP58076024A patent/JPS58208264A/ja active Pending
- 1983-04-28 GR GR71244A patent/GR78540B/el unknown
- 1983-04-29 GB GB08311823A patent/GB2119379B/en not_active Expired
- 1983-04-29 EP EP83302429A patent/EP0093590A1/en not_active Ceased
- 1983-05-02 DK DK194083A patent/DK194083A/da not_active Application Discontinuation
- 1983-05-02 KR KR1019830001861A patent/KR840005092A/ko not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
GB8311823D0 (en) | 1983-06-02 |
US4483986A (en) | 1984-11-20 |
EP0093590A1 (en) | 1983-11-09 |
JPS58208264A (ja) | 1983-12-03 |
GR78540B (ko) | 1984-09-27 |
DK194083A (da) | 1983-11-04 |
DK194083D0 (da) | 1983-05-02 |
GB2119379A (en) | 1983-11-16 |
GB2119379B (en) | 1986-01-22 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
E902 | Notification of reason for refusal | ||
E601 | Decision to refuse application |